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Gene ID: 80381 | CD276 Antibody Resource


CD276 Antibody Resource
Gene Full Name: 
CD276 molecule
Uniprot: 
Q5ZPR3
Protein Name: 
CD276 antigen
Nucleotide: 
XM_005254701
Alias: 
B7H3;B7-H3;B7RP-2;4Ig-B7-H3;
Ensembl: 
ENSG00000103855
Location: 
15q23-q24
HPRD: 
05756
NCBI Gene: 
80381
MIM: 
605715

Summary: 
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Function: 
May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
Subcellular location: 
Membrane; Single-pass type I membrane protein Probable.
PTM: 
Disulfide bond;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Monoclonal Antibody OASA00470 CD276 Antibody (OASA00470) Chicken FC 0.25mg $455 Details
Monoclonal Antibody OASA01752 CD276 Antibody (OASA01752) Human IHC-AFF, FC 0.2mg $465 Details
Monoclonal Antibody OASA01753 CD276 Antibody (OASA01753) Human FC 0.1mg $240 Details
Monoclonal Antibody OASA01754 CD276 Antibody (OASA01754) Human FC 0.1mg $355 Details
Monoclonal Antibody OASA01755 CD276 Antibody (OASA01755) Human FC 100 Tests $395 Details
Monoclonal Antibody OASA05124 RAT ANTI MOUSE CD276 Antibody (0.25mg) FC 0.25mg $310 Details
Polyclonal Antibody ARP63929_P050 CD276 antibody - C-terminal region (ARP63929_P050) Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat WB 50ug $289 Details
Polyclonal Antibody OAAB09063 CD276 antibody - C - terminal region (OAAB09063) Human WB 400ul $289 Details

Show all CD276 antibodies


Product Images
CD276 antibody - C-terminal region (ARP63929_P050) in Human MCF-7 cells using Western Blot

Sample Type: Human MCF-7

CD276 antibody - C - terminal region (OAAB09063) in MCF-7 cells using Western Blot

Sample Type: MCF-7

CD276 Antibody (OASA01752) in human peripheral blood monocytes cells using Flow Cytometry

Sample Type: human peripheral blood monocytes

CD276 Antibody (OASA01752) in human peripheral blood monocytes cells using Flow Cytometry

Sample Type: human peripheral blood monocytes

CD276 Antibody (OASA01752) in human peripheral blood monocytes cells using Flow Cytometry

Sample Type: human peripheral blood monocytes

CD276 Antibody (OASA01753) in human peripheral blood monocytes cells using Flow Cytometry

Sample Type: human peripheral blood monocytes

CD276 Antibody (OASA01753) in human peripheral blood monocytes cells using Flow Cytometry

Sample Type: human peripheral blood monocytes

CD276 Antibody (OASA01753) in human peripheral blood monocytes cells using Flow Cytometry

Sample Type: human peripheral blood monocytes

CD276 Antibody (OASA01754) in human peripheral blood monocytes cells using Flow Cytometry

Sample Type: human peripheral blood monocytes

CD276 Antibody (OASA01754) in human peripheral blood monocytes cells using Flow Cytometry

Sample Type: human peripheral blood monocytes

CD276 Antibody (OASA01754) in human peripheral blood monocytes cells using Flow Cytometry

Sample Type: human peripheral blood monocytes

CD276 Antibody (OASA01755) in human peripheral blood monocytes cells using Flow Cytometry

Sample Type: human peripheral blood monocytes

CD276 Antibody (OASA01755) in human peripheral blood monocytes cells using Flow Cytometry

Sample Type: human peripheral blood monocytes

CD276 Antibody (OASA01755) in human peripheral blood monocytes cells using Flow Cytometry

Sample Type: human peripheral blood monocytes


CD276 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP63929 African elephant CD276 antibody; Loxodonta africana CD276 antibody G3TE55 86.0%
ARP63929 African elephant CD276 antibody; Loxodonta africana CD276 antibody G3UHK6 86.0%
ARP63929 Bovine CD276 antibody; Bos taurus CD276 antibody Q0KIZ6 86.0%
ARP63929 Bovine CD276 antibody; Bos taurus CD276 antibody F1N2H6 86.0%
ARP63929 Cat CD276 antibody; Felis catus CD276 antibody M3W5R2 93.0%
ARP63929 Chimpanzee CD276 antibody; Pan troglodytes CD276 antibody H2Q9S0 100.0%
ARP63929 Chimpanzee CD276 antibody; Pan troglodytes CD276 antibody K7AMM0 100.0%
ARP63929 Chimpanzee CD276 antibody; Pan troglodytes CD276 antibody K7AUS5 100.0%
ARP63929 Chimpanzee CD276 antibody; Pan troglodytes CD276 antibody K7CC44 100.0%
ARP63929 Dog CD276 antibody; Canis familiaris CD276 antibody F1PDP5 93.0%
ARP63929 European domestic ferret CD276 antibody; Mustela putorius furo CD276 antibody M3Z0L4 93.0%
ARP63929 Giant panda CD276 antibody; Ailuropoda melanoleuca CD276 antibody G1LGJ7 85.0%
ARP63929 Gray short-tailed opossum CD276 antibody; Monodelphis domestica CD276 antibody K7DZ96 93.0%
ARP63929 Horse CD276 antibody; Equus caballus CD276 antibody F6SBZ3 93.0%
ARP63929 Human CD276 antibody; Homo sapiens CD276 antibody Q5ZPR3-2 100.0%
ARP63929 Human CD276 antibody; Homo sapiens CD276 antibody Q5ZPR3-4 100.0%
ARP63929 Human CD276 antibody; Homo sapiens CD276 antibody Q5ZPR3 100.0%
ARP63929 Human CD276 antibody; Homo sapiens CD276 antibody H0YL10 100.0%
ARP63929 Human CD276 antibody; Homo sapiens CD276 antibody H0YN29 100.0%
ARP63929 Mouse CD276 antibody; Mus musculus CD276 antibody A6MDC5 93.0%
ARP63929 Mouse CD276 antibody; Mus musculus CD276 antibody Q8VE98 93.0%
ARP63929 Pig CD276 antibody; Sus scrofa CD276 antibody M3VK17 93.0%
ARP63929 Pig CD276 antibody; Sus scrofa CD276 antibody F1SIC6 93.0%
ARP63929 Rabbit CD276 antibody; Oryctolagus cuniculus CD276 antibody G1TZK6 86.0%
ARP63929 Rat CD276 antibody; Rattus norvegicus CD276 antibody Q7TPB4 93.0%
ARP63929 Rhesus macaque CD276 antibody; Macaca mulatta CD276 antibody F7G5V3 100.0%
ARP63929 Rhesus macaque CD276 antibody; Macaca mulatta CD276 antibody F7GRG0 100.0%
ARP63929 Rhesus macaque CD276 antibody; Macaca mulatta CD276 antibody H9F5S6 100.0%
ARP63929 Small-eared galago CD276 antibody; Otolemur garnettii CD276 antibody H0XMF4 100.0%
ARP63929 Sumatran orangutan CD276 antibody; Pongo abelii CD276 antibody H2NNQ1 100.0%
ARP63929 Thirteen-lined ground squirrel CD276 antibody; Spermophilus tridecemlineatus CD276 antibody I3N391 92.0%
ARP63929 White-tufted-ear marmoset CD276 antibody; Callithrix jacchus CD276 antibody F6R1L0 93.0%
ARP63929 White-tufted-ear marmoset CD276 antibody; Callithrix jacchus CD276 antibody F6R1S8 93.0%
ARP63929 White-tufted-ear marmoset CD276 antibody; Callithrix jacchus CD276 antibody F6ZII2 93.0%
ARP63929 White-tufted-ear marmoset CD276 antibody; Callithrix jacchus CD276 antibody U3B2Y8 93.0%
ARP63929 White-tufted-ear marmoset CD276 antibody; Callithrix jacchus CD276 antibody F7E1E3 93.0%
ARP63929 White-tufted-ear marmoset CD276 antibody; Callithrix jacchus CD276 antibody F7F656 93.0%
ARP63929 White-tufted-ear marmoset CD276 antibody; Callithrix jacchus CD276 antibody U3BL22 93.0%
ARP63929 White-tufted-ear marmoset CD276 antibody; Callithrix jacchus CD276 antibody U3C7I0 93.0%
ARP63929 White-tufted-ear marmoset CD276 antibody; Callithrix jacchus CD276 antibody U3DLH5 93.0%
ARP63929 White-tufted-ear marmoset CD276 antibody; Callithrix jacchus CD276 antibody U3DWV2 93.0%
ARP63929 White-tufted-ear marmoset CD276 antibody; Callithrix jacchus CD276 antibody U3EAR3 93.0%
ARP63929 White-tufted-ear marmoset CD276 antibody; Callithrix jacchus CD276 antibody U3EZE8 93.0%

Tissue & Cell Line Gene Expression Data