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Gene ID: 84733 | CBX2 Antibody Resource


CBX2 Antibody Resource
Gene Full Name: 
chromobox homolog 2
Uniprot: 
Q14781
Protein Name: 
chromobox protein homolog 2
Nucleotide: 
NM_005189
Alias: 
M33;CDCA6;SRXY5;
Ensembl: 
ENSG00000173894
Location: 
17q25.3
HPRD: 
14397
NCBI Gene: 
84733
MIM: 
602770

Summary: 
This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2010]
Function: 
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.
Subcellular location: 
Nucleus .
PTM: 
Disease: 
46,XY sex reversal 5 (SRXY5) [MIM:613080]: A disorder of sex development. Affected individuals have a 46,XY karyotype but present as phenotypically normal females. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP51628_P050 CBX2 antibody - N-terminal region (ARP51628_P050) Polyclonal Bovine, Guinea pig, Horse, Human, Mouse, Rabbit WB 50ug $289 Details
Polyclonal Antibody ARP58370_P050 CBX2 antibody - middle region (ARP58370_P050) Polyclonal Bovine, Horse, Human WB 50ug $289 Details
Polyclonal Antibody OAEB00994 CBX2 Antibody (OAEB00994) Dog, Human ELISA, WB 0.1mg $289 Details
Polyclonal Antibody OAAB06202 CBX2 antibody - N-terminal region (OAAB06202) Human WB, ELISA 400ul $289 Details
Polyclonal Antibody OAAB12567 CBX2 antibody - center region (OAAB12567) Human; Mouse WB 400ul $289 Details

Show all CBX2 antibodies


Product Images
CBX2 antibody - N-terminal region (ARP51628_P050) in Hum. Adult Placenta cells using Western Blot

Sample Type: Hum. Adult Placenta

CBX2 antibody - N-terminal region (ARP51628_P050) in Hum. Fetal Heart cells using Western Blot

Sample Type: Hum. Fetal Heart

CBX2 antibody - N-terminal region (ARP51628_P050) in Hum. Fetal Liver cells using Western Blot

Sample Type: Hum. Fetal Liver

CBX2 antibody - N-terminal region (ARP51628_P050) in Human Heart cells using Western Blot

Sample Type: Human Heart

CBX2 antibody - middle region (ARP58370_P050) in Human OVCAR-3 cells using Western Blot

Sample Type: Human OVCAR-3

CBX2 antibody - N-terminal region (OAAB06202) in MDA-MB231 cells using Western Blot

Sample Type: MDA-MB231

CBX2 antibody - center region (OAAB12567) in Mouse Testis cells using Western Blot

Sample Type: Mouse Testis


CBX2 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP51628 Amami-oshima island spiny rat CBX2 antibody; Tokudaia osimensis CBX2 antibody F2Z9L0 93.0%
ARP51628 Bovine CBX2 antibody; Bos taurus CBX2 antibody F1MKU2 100.0%
ARP58370 Bovine CBX2 antibody; Bos taurus CBX2 antibody F1MKU2 86.0%
ARP51628 Cat CBX2 antibody; Felis catus CBX2 antibody M3VX32 100.0%
ARP58370 Cat CBX2 antibody; Felis catus CBX2 antibody M3VX32 79.0%
ARP51628 Chicken CBX2 antibody; Gallus gallus CBX2 antibody E1BX64 93.0%
ARP51628 Chimpanzee CBX2 antibody; Pan troglodytes CBX2 antibody H2QE05 100.0%
ARP58370 Chimpanzee CBX2 antibody; Pan troglodytes CBX2 antibody H2QE05 100.0%
ARP51628 Chinese softshell turtle CBX2 antibody; Pelodiscus sinensis CBX2 antibody K7F443 93.0%
ARP51628 Collared flycatcher CBX2 antibody; Ficedula albicollis CBX2 antibody U3KCW9 100.0%
ARP51628 Dog CBX2 antibody; Canis familiaris CBX2 antibody J9NVW3 100.0%
ARP51628 Domestic duck CBX2 antibody; Anas platyrhynchos CBX2 antibody U3IK30 93.0%
ARP51628 European domestic ferret CBX2 antibody; Mustela putorius furo CBX2 antibody M3YLH7 100.0%
ARP51628 Gray short-tailed opossum CBX2 antibody; Monodelphis domestica CBX2 antibody F6U023 100.0%
ARP51628 Horse CBX2 antibody; Equus caballus CBX2 antibody F6W7W6 93.0%
ARP58370 Horse CBX2 antibody; Equus caballus CBX2 antibody F6W7W6 93.0%
ARP51628 Human CBX2 antibody; Homo sapiens CBX2 antibody Q14781 100.0%
ARP58370 Human CBX2 antibody; Homo sapiens CBX2 antibody Q14781 100.0%
ARP51628 Mouse CBX2 antibody; Mus musculus CBX2 antibody P30658 100.0%
ARP51628 Mouse CBX2 antibody; Mus musculus CBX2 antibody Q3TZG6 100.0%
ARP51628 Northern white-cheeked gibbon CBX2 antibody; Nomascus leucogenys CBX2 antibody M3Z9F2 100.0%
ARP58370 Northern white-cheeked gibbon CBX2 antibody; Nomascus leucogenys CBX2 antibody M3Z9F2 100.0%
ARP51628 Pig CBX2 antibody; Sus scrofa CBX2 antibody I3LU16 100.0%
ARP58370 Pig CBX2 antibody; Sus scrofa CBX2 antibody I3LU16 79.0%
ARP51628 Rabbit CBX2 antibody; Oryctolagus cuniculus CBX2 antibody G1SWV5 100.0%
ARP51628 Rabbit CBX2 antibody; Oryctolagus cuniculus CBX2 antibody G1TMP5 100.0%
ARP51628 Rat CBX2 antibody; Rattus norvegicus CBX2 antibody M0RE14 93.0%
ARP58370 Rat CBX2 antibody; Rattus norvegicus CBX2 antibody M0RE14 79.0%
ARP58370 Rhesus macaque CBX2 antibody; Macaca mulatta CBX2 antibody F7FLI7 100.0%
ARP58370 Rhesus macaque CBX2 antibody; Macaca mulatta CBX2 antibody I0FVS0 100.0%
ARP51628 Rhesus macaque CBX2 antibody; Macaca mulatta CBX2 antibody F7FLI7 93.0%
ARP51628 Rhesus macaque CBX2 antibody; Macaca mulatta CBX2 antibody I0FVS0 93.0%
ARP39073 salmon louse CBX2 antibody; Lepeophtheirus salmonis CBX2 antibody D3PGN7 100.0%
ARP39421 salmon louse CBX2 antibody; Lepeophtheirus salmonis CBX2 antibody D3PGN7 93.0%
ARP51628 Small-eared galago CBX2 antibody; Otolemur garnettii CBX2 antibody H0XFF6 100.0%
ARP58370 Small-eared galago CBX2 antibody; Otolemur garnettii CBX2 antibody H0XFF6 86.0%
ARP51628 Tasmanian devil CBX2 antibody; Sarcophilus harrisii CBX2 antibody G3W934 100.0%
ARP51628 Thirteen-lined ground squirrel CBX2 antibody; Spermophilus tridecemlineatus CBX2 antibody I3MUT1 100.0%
ARP58370 Thirteen-lined ground squirrel CBX2 antibody; Spermophilus tridecemlineatus CBX2 antibody I3MUT1 79.0%
ARP51628 White-tufted-ear marmoset CBX2 antibody; Callithrix jacchus CBX2 antibody F7EQP8 100.0%
ARP51628 White-tufted-ear marmoset CBX2 antibody; Callithrix jacchus CBX2 antibody F7EQZ9 100.0%
ARP58370 White-tufted-ear marmoset CBX2 antibody; Callithrix jacchus CBX2 antibody F7EQP8 93.0%
ARP58370 White-tufted-ear marmoset CBX2 antibody; Callithrix jacchus CBX2 antibody F7EQZ9 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas215989_at721_B_lymphoblasts8.9507.190Details
BioGPS Gene Atlas215989_atAdipocyte7.0007.190Details
BioGPS Gene Atlas215989_atAdrenalCortex7.3007.190Details
BioGPS Gene Atlas215989_atAdrenalgland6.0507.190Details
BioGPS Gene Atlas215989_atAmygdala7.5007.190Details
BioGPS Gene Atlas215989_atAppendix7.0507.190Details
BioGPS Gene Atlas215989_atAtrioventricularNode5.3007.190Details
BioGPS Gene Atlas215989_atBDCA4+_DentriticCells7.6007.190Details
BioGPS Gene Atlas215989_atBonemarrow7.4507.190Details
BioGPS Gene Atlas215989_atBronchialEpithelialCells7.0007.190Details
BioGPS Gene Atlas215989_atCD105+_Endothelial6.0007.190Details
BioGPS Gene Atlas215989_atCD14+_Monocytes7.4507.190Details
BioGPS Gene Atlas215989_atCD19+_BCells(neg._sel.)6.3507.190Details
BioGPS Gene Atlas215989_atCD33+_Myeloid9.1007.190Details
BioGPS Gene Atlas215989_atCD34+7.4507.190Details
BioGPS Gene Atlas215989_atCD4+_Tcells7.7507.190Details
BioGPS Gene Atlas215989_atCD56+_NKCells6.9507.190Details
BioGPS Gene Atlas215989_atCD71+_EarlyErythroid6.5507.190Details
BioGPS Gene Atlas215989_atCD8+_Tcells6.6507.190Details
BioGPS Gene Atlas215989_atCardiacMyocytes8.9507.190Details
BioGPS Gene Atlas215989_atCaudatenucleus6.3507.190Details
BioGPS Gene Atlas215989_atCerebellum8.6507.190Details
BioGPS Gene Atlas215989_atCerebellumPeduncles7.9007.190Details
BioGPS Gene Atlas215989_atCiliaryGanglion4.9507.190Details
BioGPS Gene Atlas215989_atCingulateCortex7.7007.190Details
BioGPS Gene Atlas215989_atColorectaladenocarcinoma7.0507.190Details
BioGPS Gene Atlas215989_atDorsalRootGanglion5.3507.190Details
BioGPS Gene Atlas215989_atFetalThyroid6.8007.190Details
BioGPS Gene Atlas215989_atFetalbrain7.0507.190Details
BioGPS Gene Atlas215989_atFetalliver6.1007.190Details
BioGPS Gene Atlas215989_atFetallung5.9007.190Details
BioGPS Gene Atlas215989_atGlobusPallidus5.9507.190Details
BioGPS Gene Atlas215989_atHeart8.9007.190Details
BioGPS Gene Atlas215989_atHypothalamus7.7007.190Details
BioGPS Gene Atlas215989_atKidney5.9507.190Details
BioGPS Gene Atlas215989_atLeukemia_chronicMyelogenousK-5626.3507.190Details
BioGPS Gene Atlas215989_atLeukemia_promyelocytic-HL-606.2007.190Details
BioGPS Gene Atlas215989_atLeukemialymphoblastic(MOLT-4)5.7007.190Details
BioGPS Gene Atlas215989_atLiver11.2007.190Details
BioGPS Gene Atlas215989_atLung7.8007.190Details
BioGPS Gene Atlas215989_atLymphnode6.1007.190Details
BioGPS Gene Atlas215989_atLymphoma_burkitts(Daudi)8.9507.190Details
BioGPS Gene Atlas215989_atLymphoma_burkitts(Raji)9.9007.190Details
BioGPS Gene Atlas215989_atMedullaOblongata6.5007.190Details
BioGPS Gene Atlas215989_atOccipitalLobe6.3507.190Details
BioGPS Gene Atlas215989_atOlfactoryBulb5.5507.190Details
BioGPS Gene Atlas215989_atOvary5.2007.190Details
BioGPS Gene Atlas215989_atPancreas4.8007.190Details
BioGPS Gene Atlas215989_atPancreaticIslet7.6507.190Details
BioGPS Gene Atlas215989_atParietalLobe9.6507.190Details
BioGPS Gene Atlas215989_atPituitary8.2507.190Details
BioGPS Gene Atlas215989_atPlacenta7.3507.190Details
BioGPS Gene Atlas215989_atPons6.6507.190Details
BioGPS Gene Atlas215989_atPrefrontalCortex8.9007.190Details
BioGPS Gene Atlas215989_atProstate8.3007.190Details
BioGPS Gene Atlas215989_atSalivarygland5.6007.190Details
BioGPS Gene Atlas215989_atSkeletalMuscle8.0507.190Details
BioGPS Gene Atlas215989_atSkin5.3007.190Details
BioGPS Gene Atlas215989_atSmoothMuscle8.0507.190Details
BioGPS Gene Atlas215989_atSpinalcord7.5507.190Details
BioGPS Gene Atlas215989_atSubthalamicNucleus6.5007.190Details
BioGPS Gene Atlas215989_atSuperiorCervicalGanglion7.8007.190Details
BioGPS Gene Atlas215989_atTemporalLobe6.4507.190Details
BioGPS Gene Atlas215989_atTestis7.0507.190Details
BioGPS Gene Atlas215989_atTestisGermCell6.0007.190Details
BioGPS Gene Atlas215989_atTestisIntersitial6.9507.190Details
BioGPS Gene Atlas215989_atTestisLeydigCell7.0507.190Details
BioGPS Gene Atlas215989_atTestisSeminiferousTubule7.5507.190Details
BioGPS Gene Atlas215989_atThalamus7.2007.190Details
BioGPS Gene Atlas215989_atThymus5.6007.190Details
BioGPS Gene Atlas215989_atThyroid8.9007.190Details
BioGPS Gene Atlas215989_atTongue6.8007.190Details
BioGPS Gene Atlas215989_atTonsil6.8507.190Details
BioGPS Gene Atlas215989_atTrachea10.0507.190Details
BioGPS Gene Atlas215989_atTrigeminalGanglion6.9007.190Details
BioGPS Gene Atlas215989_atUterus5.8507.190Details
BioGPS Gene Atlas215989_atUterusCorpus6.2507.190Details
BioGPS Gene Atlas215989_atWholeBlood7.6507.190Details
BioGPS Gene Atlas215989_atWholebrain6.5007.190Details
BioGPS Gene Atlas215989_atcolon7.1007.190Details
BioGPS Gene Atlas215989_atpineal_day8.3007.190Details
BioGPS Gene Atlas215989_atpineal_night7.3207.190Details
BioGPS Gene Atlas215989_atretina8.5257.190Details
BioGPS Gene Atlas215989_atsmall_intestine6.8507.190Details
BioGPS NCI60215989_at7865.9946.020Details
BioGPS NCI60215989_atA1725.7106.020Details
BioGPS NCI60215989_atA2045.8256.020Details
BioGPS NCI60215989_atA3615.9626.020Details
BioGPS NCI60215989_atA4985.9006.020Details
BioGPS NCI60215989_atA5495.9596.020Details
BioGPS NCI60215989_atACC36.0506.020Details
BioGPS NCI60215989_atACHN5.3806.020Details
BioGPS NCI60215989_atALVA316.0246.020Details
BioGPS NCI60215989_atCAKI16.0176.020Details
BioGPS NCI60215989_atCCRT CEM7.6956.020Details
BioGPS NCI60215989_atCOLO2055.8716.020Details
BioGPS NCI60215989_atDLD17.1256.020Details
BioGPS NCI60215989_atDU1455.7046.020Details
BioGPS NCI60215989_atEKVX5.5626.020Details
BioGPS NCI60215989_atGM1335.9936.020Details
BioGPS NCI60215989_atGM16006.0236.020Details
BioGPS NCI60215989_atGM23135.9436.020Details
BioGPS NCI60215989_atGM23455.8896.020Details
BioGPS NCI60215989_atGM24936.0576.020Details
BioGPS NCI60215989_atGM976.2366.020Details
BioGPS NCI60215989_atHCC29985.2136.020Details
BioGPS NCI60215989_atHCT1165.8486.020Details
BioGPS NCI60215989_atHCT155.3086.020Details
BioGPS NCI60215989_atHEK 293 T-rex5.9596.020Details
BioGPS NCI60215989_atHEK 293T5.9046.020Details
BioGPS NCI60215989_atHEK2936.4526.020Details
BioGPS NCI60215989_atHELA5.4416.020Details
BioGPS NCI60215989_atHEPG25.8786.020Details
BioGPS NCI60215989_atHL606.1196.020Details
BioGPS NCI60215989_atHOP625.8686.020Details
BioGPS NCI60215989_atHOP925.6236.020Details
BioGPS NCI60215989_atHS578T5.8386.020Details
BioGPS NCI60215989_atHSG5.7676.020Details
BioGPS NCI60215989_atHT10805.7646.020Details
BioGPS NCI60215989_atHT296.0986.020Details
BioGPS NCI60215989_atIGROV15.8506.020Details
BioGPS NCI60215989_atIOSE805.8596.020Details
BioGPS NCI60215989_atJURKAT8.2676.020Details
BioGPS NCI60215989_atK5626.7016.020Details
BioGPS NCI60215989_atKM126.0616.020Details
BioGPS NCI60215989_atLN185.6986.020Details
BioGPS NCI60215989_atLNCAP5.8866.020Details
BioGPS NCI60215989_atLOX IMVI5.8806.020Details
BioGPS NCI60215989_atM145.8146.020Details
BioGPS NCI60215989_atMALME 3M6.3886.020Details
BioGPS NCI60215989_atMCF75.7936.020Details
BioGPS NCI60215989_atMD MB2315.9556.020Details
BioGPS NCI60215989_atMDA MB4356.4746.020Details
BioGPS NCI60215989_atMOLT46.0056.020Details
BioGPS NCI60215989_atNCI 4606.0826.020Details
BioGPS NCI60215989_atNCI H2265.9666.020Details
BioGPS NCI60215989_atNCI H235.8806.020Details
BioGPS NCI60215989_atNCI H322M5.9116.020Details
BioGPS NCI60215989_atNCVADR RES5.6966.020Details
BioGPS NCI60215989_atOVCAR36.0306.020Details
BioGPS NCI60215989_atOVCAR45.8696.020Details
BioGPS NCI60215989_atOVCAR55.6366.020Details
BioGPS NCI60215989_atOVCAR85.6606.020Details
BioGPS NCI60215989_atPANC15.9626.020Details
BioGPS NCI60215989_atRL76.0996.020Details
BioGPS NCI60215989_atRPMI 82265.9506.020Details
BioGPS NCI60215989_atRS118466.3196.020Details
BioGPS NCI60215989_atRXF3935.8686.020Details
BioGPS NCI60215989_atSAOS26.8586.020Details
BioGPS NCI60215989_atSF2685.8966.020Details
BioGPS NCI60215989_atSF2955.8276.020Details
BioGPS NCI60215989_atSF5395.6606.020Details
BioGPS NCI60215989_atSHSYSY+RA10.0556.020Details
BioGPS NCI60215989_atSHSYSY-RA7.0766.020Details
BioGPS NCI60215989_atSKMEL25.8836.020Details
BioGPS NCI60215989_atSKMEL285.8926.020Details
BioGPS NCI60215989_atSKMEL55.7676.020Details
BioGPS NCI60215989_atSKOV35.9766.020Details
BioGPS NCI60215989_atSN12C5.8076.020Details
BioGPS NCI60215989_atSNB195.6846.020Details
BioGPS NCI60215989_atSNB755.8786.020Details
BioGPS NCI60215989_atSR5.9536.020Details
BioGPS NCI60215989_atSW6206.0516.020Details
BioGPS NCI60215989_atT245.9666.020Details
BioGPS NCI60215989_atT3M46.3906.020Details
BioGPS NCI60215989_atTK105.8576.020Details
BioGPS NCI60215989_atU1185.7406.020Details
BioGPS NCI60215989_atU1385.6406.020Details
BioGPS NCI60215989_atU20S6.6986.020Details
BioGPS NCI60215989_atU2515.8416.020Details
BioGPS NCI60215989_atU875.5636.020Details
BioGPS NCI60215989_atUACC2575.8006.020Details
BioGPS NCI60215989_atUACC625.9426.020Details
BioGPS NCI60215989_atUO315.6356.020Details
BioGPS NCI60215989_atZR75_16.0126.020Details
BioGPS NCI60215989_atastrocytes5.9446.020Details
BioGPS NCI60215989_athuh-76.1096.020Details