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Gene ID: 347732 | CATSPER3 Antibody Resource


CATSPER3 Antibody Resource
Gene Full Name: 
cation channel, sperm associated 3
Uniprot: 
Q86XQ3
Protein Name: 
cation channel sperm-associated protein 3
Nucleotide: 
NM_178019
Alias: 
CACRC;
Ensembl: 
ENSG00000152705
Location: 
5q31.1
HPRD: 
16447
NCBI Gene: 
347732
MIM: 
609120

Summary: 
Function: 
Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH.
Subcellular location: 
Cell projection › cilium › flagellum membrane; Multi-pass membrane protein. Note: Specifically located in the principal piece of sperm tail.
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP35519_P050 CATSPER3 Antibody (ARP35519_P050) Polyclonal Dog, Human Not tested 50 ug $125 Details
Polyclonal Antibody OAAB09300 CTSR3 antibody - C - terminal region (OAAB09300) Human WB, IHC 400ul $289 Details

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Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP35519 Chimpanzee CATSPER3 antibody; Pan troglodytes CATSPER3 antibody H2QRI6 100.0%
ARP35519 Dog CATSPER3 antibody; Canis familiaris CATSPER3 antibody E2RRG6 85.0%
ARP35519 Dog CATSPER3 antibody; Canis familiaris CATSPER3 antibody J9P2N7 85.0%
ARP35519 Human CATSPER3 antibody; Homo sapiens CATSPER3 antibody Q86XQ3 100.0%
ARP35519 Rhesus macaque CATSPER3 antibody; Macaca mulatta CATSPER3 antibody F7BHK8 100.0%
ARP35519 Sumatran orangutan CATSPER3 antibody; Pongo abelii CATSPER3 antibody H2PGL1 100.0%
ARP35519 White-tufted-ear marmoset CATSPER3 antibody; Callithrix jacchus CATSPER3 antibody F7H7N6 86.0%
ARP35519 White-tufted-ear marmoset CATSPER3 antibody; Callithrix jacchus CATSPER3 antibody F7HWL7 86.0%

Tissue & Cell Line Gene Expression Data