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Gene ID: 9994 | CASP8AP2 Antibody Resource


CASP8AP2 Antibody Resource
Gene Full Name: 
caspase 8 associated protein 2
Uniprot: 
Q9UKL3
Protein Name: 
CASP8-associated protein 2
Nucleotide: 
NM_012115
Alias: 
CED-4;FLASH;RIP25;
Ensembl: 
Location: 
6q15
HPRD: 
06048
NCBI Gene: 
9994
MIM: 
606880

Summary: 
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]
Function: 
Participates in TNF-alpha-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation. Involved in TNF-alpha-induced activation of NF-kappa-B via a TRAF2-dependent pathway. Acts as a downstream mediator for CASP8-induced activation of NF-kappa-B. Required for the activation of CASP8 in FAS-mediated apoptosis. Required for histone gene transcription and progression through S phase. UniProtKB Q9WUF3
Subcellular location: 
Cytoplasm. Nucleus. Nucleus › PML body. Mitochondrion. Note: Exported from the nucleus to the mitochondria upon FAS activation.
PTM: 
Acetylation;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP50555_P050 CASP8AP2 antibody - N-terminal region (ARP50555_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Pig, Rat WB 50ug $289 Details
Polyclonal Antibody OASA07751 CASP8AP2 antibody - C-terminal region (OASA07751) Human WB 0.1mg $330 Details
Polyclonal Antibody OASA07752 CASP8AP2 antibody - C-terminal region (OASA07752) Human WB 50ug $220 Details
Polyclonal Antibody ARP50556_P050 CASP8AP2 Antibody (ARP50556_P050) Polyclonal Human Not tested 50 ug $125 Details

Show all CASP8AP2 antibodies


Product Images
CASP8AP2 antibody - N-terminal region (ARP50555_P050) in Human HeLa cells using Western Blot

Sample Type: Human HeLa

CASP8AP2 antibody - C-terminal region (OASA07751) in HeLa cells using Western Blot

Sample Type: HeLa

CASP8AP2 antibody - C-terminal region (OASA07752) in HeLa cells using Western Blot

Sample Type: HeLa


CASP8AP2 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP50555 African elephant CASP8AP2 antibody; Loxodonta africana CASP8AP2 antibody G3T9D2 100.0%
ARP50555 Bovine CASP8AP2 antibody; Bos taurus CASP8AP2 antibody E1BLU4 93.0%
ARP50555 Cat CASP8AP2 antibody; Felis catus CASP8AP2 antibody M3WPY8 86.0%
ARP50555 Chimpanzee CASP8AP2 antibody; Pan troglodytes CASP8AP2 antibody K7C6N7 100.0%
ARP50556 Chimpanzee CASP8AP2 antibody; Pan troglodytes CASP8AP2 antibody K7C6N7 100.0%
ARP50555 Dog CASP8AP2 antibody; Canis familiaris CASP8AP2 antibody E2R4M6 86.0%
ARP70337 Dog CASP8AP2 antibody; Canis familiaris CASP8AP2 antibody E2R4M6 79.0%
ARP70337 Duckbill platypus CASP8AP2 antibody; Ornithorhynchus anatinus CASP8AP2 antibody F7D2Y4 79.0%
ARP50555 European domestic ferret CASP8AP2 antibody; Mustela putorius furo CASP8AP2 antibody M3YCI8 93.0%
ARP50555 Giant panda CASP8AP2 antibody; Ailuropoda melanoleuca CASP8AP2 antibody G1LA74 86.0%
ARP50555 Giant panda CASP8AP2 antibody; Ailuropoda melanoleuca CASP8AP2 antibody G1LA79 86.0%
ARP50555 Gray short-tailed opossum CASP8AP2 antibody; Monodelphis domestica CASP8AP2 antibody F7BU08 100.0%
ARP50555 Horse CASP8AP2 antibody; Equus caballus CASP8AP2 antibody F6UGU4 93.0%
ARP50555 Human CASP8AP2 antibody; Homo sapiens CASP8AP2 antibody Q9UKL3 100.0%
ARP50556 Human CASP8AP2 antibody; Homo sapiens CASP8AP2 antibody Q9UKL3 100.0%
ARP50555 Human CASP8AP2 antibody; Homo sapiens CASP8AP2 antibody A7E2C0 100.0%
ARP50556 Human CASP8AP2 antibody; Homo sapiens CASP8AP2 antibody A7E2C0 100.0%
ARP50555 Mouse CASP8AP2 antibody; Mus musculus CASP8AP2 antibody Q3TNP9 100.0%
ARP50555 Mouse CASP8AP2 antibody; Mus musculus CASP8AP2 antibody Q3UQU1 100.0%
ARP50555 Mouse CASP8AP2 antibody; Mus musculus CASP8AP2 antibody Q9WUF3 100.0%
ARP50555 Northern white-cheeked gibbon CASP8AP2 antibody; Nomascus leucogenys CASP8AP2 antibody G1RS99 100.0%
ARP50556 Northern white-cheeked gibbon CASP8AP2 antibody; Nomascus leucogenys CASP8AP2 antibody G1RS99 86.0%
ARP50555 Pig CASP8AP2 antibody; Sus scrofa CASP8AP2 antibody F1RY19 93.0%
ARP70337 Pig CASP8AP2 antibody; Sus scrofa CASP8AP2 antibody F1RY19 79.0%
ARP50555 Rabbit CASP8AP2 antibody; Oryctolagus cuniculus CASP8AP2 antibody G1SG17 93.0%
ARP50555 Rat CASP8AP2 antibody; Rattus norvegicus CASP8AP2 antibody D4A7V6 100.0%
ARP50555 Rhesus macaque CASP8AP2 antibody; Macaca mulatta CASP8AP2 antibody H9G2P7 100.0%
ARP50555 Rhesus macaque CASP8AP2 antibody; Macaca mulatta CASP8AP2 antibody F7HPB6 100.0%
ARP50556 Rhesus macaque CASP8AP2 antibody; Macaca mulatta CASP8AP2 antibody H9G2P7 93.0%
ARP50556 Rhesus macaque CASP8AP2 antibody; Macaca mulatta CASP8AP2 antibody F7HPB6 93.0%
ARP50555 Sumatran orangutan CASP8AP2 antibody; Pongo abelii CASP8AP2 antibody H2PJT9 100.0%
ARP50556 Sumatran orangutan CASP8AP2 antibody; Pongo abelii CASP8AP2 antibody H2PJT9 93.0%
ARP50555 White-tufted-ear marmoset CASP8AP2 antibody; Callithrix jacchus CASP8AP2 antibody U3D5L3 100.0%
ARP50555 White-tufted-ear marmoset CASP8AP2 antibody; Callithrix jacchus CASP8AP2 antibody U3FRK4 100.0%
ARP50555 White-tufted-ear marmoset CASP8AP2 antibody; Callithrix jacchus CASP8AP2 antibody F7BDP9 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas222201_s_at721_B_lymphoblasts24.8008.330Details
BioGPS Gene Atlas222201_s_atAdipocyte5.8008.330Details
BioGPS Gene Atlas222201_s_atAdrenalCortex6.3508.330Details
BioGPS Gene Atlas222201_s_atAdrenalgland5.4008.330Details
BioGPS Gene Atlas222201_s_atAmygdala6.4508.330Details
BioGPS Gene Atlas222201_s_atAppendix7.3008.330Details
BioGPS Gene Atlas222201_s_atAtrioventricularNode5.0008.330Details
BioGPS Gene Atlas222201_s_atBDCA4+_DentriticCells11.6008.330Details
BioGPS Gene Atlas222201_s_atBonemarrow6.2008.330Details
BioGPS Gene Atlas222201_s_atBronchialEpithelialCells5.4508.330Details
BioGPS Gene Atlas222201_s_atCD105+_Endothelial26.8508.330Details
BioGPS Gene Atlas222201_s_atCD14+_Monocytes6.2508.330Details
BioGPS Gene Atlas222201_s_atCD19+_BCells(neg._sel.)9.4508.330Details
BioGPS Gene Atlas222201_s_atCD33+_Myeloid6.7008.330Details
BioGPS Gene Atlas222201_s_atCD34+20.0508.330Details
BioGPS Gene Atlas222201_s_atCD4+_Tcells42.2008.330Details
BioGPS Gene Atlas222201_s_atCD56+_NKCells18.3508.330Details
BioGPS Gene Atlas222201_s_atCD71+_EarlyErythroid18.3508.330Details
BioGPS Gene Atlas222201_s_atCD8+_Tcells42.9508.330Details
BioGPS Gene Atlas222201_s_atCardiacMyocytes8.3508.330Details
BioGPS Gene Atlas222201_s_atCaudatenucleus6.2508.330Details
BioGPS Gene Atlas222201_s_atCerebellum4.8508.330Details
BioGPS Gene Atlas222201_s_atCerebellumPeduncles8.2008.330Details
BioGPS Gene Atlas222201_s_atCiliaryGanglion4.4008.330Details
BioGPS Gene Atlas222201_s_atCingulateCortex6.5508.330Details
BioGPS Gene Atlas222201_s_atColorectaladenocarcinoma5.9008.330Details
BioGPS Gene Atlas222201_s_atDorsalRootGanglion4.7508.330Details
BioGPS Gene Atlas222201_s_atFetalThyroid5.7508.330Details
BioGPS Gene Atlas222201_s_atFetalbrain8.0008.330Details
BioGPS Gene Atlas222201_s_atFetalliver6.2008.330Details
BioGPS Gene Atlas222201_s_atFetallung4.5008.330Details
BioGPS Gene Atlas222201_s_atGlobusPallidus5.3008.330Details
BioGPS Gene Atlas222201_s_atHeart8.0008.330Details
BioGPS Gene Atlas222201_s_atHypothalamus7.5008.330Details
BioGPS Gene Atlas222201_s_atKidney5.1008.330Details
BioGPS Gene Atlas222201_s_atLeukemia_chronicMyelogenousK-5625.5508.330Details
BioGPS Gene Atlas222201_s_atLeukemia_promyelocytic-HL-605.3508.330Details
BioGPS Gene Atlas222201_s_atLeukemialymphoblastic(MOLT-4)18.0008.330Details
BioGPS Gene Atlas222201_s_atLiver8.3508.330Details
BioGPS Gene Atlas222201_s_atLung6.1508.330Details
BioGPS Gene Atlas222201_s_atLymphnode11.4008.330Details
BioGPS Gene Atlas222201_s_atLymphoma_burkitts(Daudi)10.8508.330Details
BioGPS Gene Atlas222201_s_atLymphoma_burkitts(Raji)8.3508.330Details
BioGPS Gene Atlas222201_s_atMedullaOblongata5.4008.330Details
BioGPS Gene Atlas222201_s_atOccipitalLobe6.6008.330Details
BioGPS Gene Atlas222201_s_atOlfactoryBulb4.4508.330Details
BioGPS Gene Atlas222201_s_atOvary4.4508.330Details
BioGPS Gene Atlas222201_s_atPancreas4.7508.330Details
BioGPS Gene Atlas222201_s_atPancreaticIslet6.1508.330Details
BioGPS Gene Atlas222201_s_atParietalLobe7.2508.330Details
BioGPS Gene Atlas222201_s_atPituitary6.9008.330Details
BioGPS Gene Atlas222201_s_atPlacenta5.4508.330Details
BioGPS Gene Atlas222201_s_atPons5.8008.330Details
BioGPS Gene Atlas222201_s_atPrefrontalCortex10.7508.330Details
BioGPS Gene Atlas222201_s_atProstate6.4508.330Details
BioGPS Gene Atlas222201_s_atSalivarygland5.4008.330Details
BioGPS Gene Atlas222201_s_atSkeletalMuscle7.3508.330Details
BioGPS Gene Atlas222201_s_atSkin5.0508.330Details
BioGPS Gene Atlas222201_s_atSmoothMuscle6.6008.330Details
BioGPS Gene Atlas222201_s_atSpinalcord6.3008.330Details
BioGPS Gene Atlas222201_s_atSubthalamicNucleus5.7008.330Details
BioGPS Gene Atlas222201_s_atSuperiorCervicalGanglion8.8008.330Details
BioGPS Gene Atlas222201_s_atTemporalLobe5.7008.330Details
BioGPS Gene Atlas222201_s_atTestis4.9508.330Details
BioGPS Gene Atlas222201_s_atTestisGermCell4.9008.330Details
BioGPS Gene Atlas222201_s_atTestisIntersitial4.8508.330Details
BioGPS Gene Atlas222201_s_atTestisLeydigCell6.7008.330Details
BioGPS Gene Atlas222201_s_atTestisSeminiferousTubule5.0508.330Details
BioGPS Gene Atlas222201_s_atThalamus6.4508.330Details
BioGPS Gene Atlas222201_s_atThymus4.6008.330Details
BioGPS Gene Atlas222201_s_atThyroid7.5008.330Details
BioGPS Gene Atlas222201_s_atTongue6.1508.330Details
BioGPS Gene Atlas222201_s_atTonsil6.1508.330Details
BioGPS Gene Atlas222201_s_atTrachea4.8508.330Details
BioGPS Gene Atlas222201_s_atTrigeminalGanglion10.5008.330Details
BioGPS Gene Atlas222201_s_atUterus6.1508.330Details
BioGPS Gene Atlas222201_s_atUterusCorpus5.4008.330Details
BioGPS Gene Atlas222201_s_atWholeBlood8.1508.330Details
BioGPS Gene Atlas222201_s_atWholebrain4.9008.330Details
BioGPS Gene Atlas222201_s_atcolon5.5508.330Details
BioGPS Gene Atlas222201_s_atpineal_day7.5608.330Details
BioGPS Gene Atlas222201_s_atpineal_night7.1208.330Details
BioGPS Gene Atlas222201_s_atretina6.8008.330Details
BioGPS Gene Atlas222201_s_atsmall_intestine5.2508.330Details
BioGPS NCI60222201_s_at78661.29582.530Details
BioGPS NCI60222201_s_atA17266.37182.530Details
BioGPS NCI60222201_s_atA204117.35182.530Details
BioGPS NCI60222201_s_atA36126.56182.530Details
BioGPS NCI60222201_s_atA49822.89982.530Details
BioGPS NCI60222201_s_atA54947.84382.530Details
BioGPS NCI60222201_s_atACC384.66482.530Details
BioGPS NCI60222201_s_atACHN18.54982.530Details
BioGPS NCI60222201_s_atALVA3119.38082.530Details
BioGPS NCI60222201_s_atCAKI123.95582.530Details
BioGPS NCI60222201_s_atCCRT CEM41.67182.530Details
BioGPS NCI60222201_s_atCOLO20528.02582.530Details
BioGPS NCI60222201_s_atDLD154.57682.530Details
BioGPS NCI60222201_s_atDU145115.07182.530Details
BioGPS NCI60222201_s_atEKVX37.15282.530Details
BioGPS NCI60222201_s_atGM133103.90882.530Details
BioGPS NCI60222201_s_atGM1600147.20782.530Details
BioGPS NCI60222201_s_atGM2313141.36982.530Details
BioGPS NCI60222201_s_atGM234599.59382.530Details
BioGPS NCI60222201_s_atGM249333.67182.530Details
BioGPS NCI60222201_s_atGM9768.92882.530Details
BioGPS NCI60222201_s_atHCC299885.25582.530Details
BioGPS NCI60222201_s_atHCT11684.84782.530Details
BioGPS NCI60222201_s_atHCT1581.47582.530Details
BioGPS NCI60222201_s_atHEK 293 T-rex113.23882.530Details
BioGPS NCI60222201_s_atHEK 293T716.83282.530Details
BioGPS NCI60222201_s_atHEK293508.13582.530Details
BioGPS NCI60222201_s_atHELA53.97482.530Details
BioGPS NCI60222201_s_atHEPG235.82282.530Details
BioGPS NCI60222201_s_atHL6030.82182.530Details
BioGPS NCI60222201_s_atHOP6228.62182.530Details
BioGPS NCI60222201_s_atHOP9227.57182.530Details
BioGPS NCI60222201_s_atHS578T43.68982.530Details
BioGPS NCI60222201_s_atHSG26.83482.530Details
BioGPS NCI60222201_s_atHT108019.85582.530Details
BioGPS NCI60222201_s_atHT2974.21882.530Details
BioGPS NCI60222201_s_atIGROV127.04682.530Details
BioGPS NCI60222201_s_atIOSE8045.46582.530Details
BioGPS NCI60222201_s_atJURKAT213.70582.530Details
BioGPS NCI60222201_s_atK562120.83882.530Details
BioGPS NCI60222201_s_atKM1286.22682.530Details
BioGPS NCI60222201_s_atLN1827.97182.530Details
BioGPS NCI60222201_s_atLNCAP18.02982.530Details
BioGPS NCI60222201_s_atLOX IMVI24.77482.530Details
BioGPS NCI60222201_s_atM1430.96282.530Details
BioGPS NCI60222201_s_atMALME 3M52.14182.530Details
BioGPS NCI60222201_s_atMCF7108.75382.530Details
BioGPS NCI60222201_s_atMD MB23123.97982.530Details
BioGPS NCI60222201_s_atMDA MB43517.43582.530Details
BioGPS NCI60222201_s_atMOLT4107.08582.530Details
BioGPS NCI60222201_s_atNCI 46032.06182.530Details
BioGPS NCI60222201_s_atNCI H22634.02582.530Details
BioGPS NCI60222201_s_atNCI H2337.45382.530Details
BioGPS NCI60222201_s_atNCI H322M49.99982.530Details
BioGPS NCI60222201_s_atNCVADR RES229.83582.530Details
BioGPS NCI60222201_s_atOVCAR3119.46582.530Details
BioGPS NCI60222201_s_atOVCAR456.55782.530Details
BioGPS NCI60222201_s_atOVCAR568.26482.530Details
BioGPS NCI60222201_s_atOVCAR8181.85582.530Details
BioGPS NCI60222201_s_atPANC172.93882.530Details
BioGPS NCI60222201_s_atRL7204.84382.530Details
BioGPS NCI60222201_s_atRPMI 822629.05382.530Details
BioGPS NCI60222201_s_atRS1184696.38982.530Details
BioGPS NCI60222201_s_atRXF39318.78782.530Details
BioGPS NCI60222201_s_atSAOS261.90782.530Details
BioGPS NCI60222201_s_atSF26850.43682.530Details
BioGPS NCI60222201_s_atSF29516.88382.530Details
BioGPS NCI60222201_s_atSF539138.47582.530Details
BioGPS NCI60222201_s_atSHSYSY+RA121.33982.530Details
BioGPS NCI60222201_s_atSHSYSY-RA125.25282.530Details
BioGPS NCI60222201_s_atSKMEL242.64182.530Details
BioGPS NCI60222201_s_atSKMEL2841.22082.530Details
BioGPS NCI60222201_s_atSKMEL515.43282.530Details
BioGPS NCI60222201_s_atSKOV3160.27882.530Details
BioGPS NCI60222201_s_atSN12C23.81582.530Details
BioGPS NCI60222201_s_atSNB19147.03782.530Details
BioGPS NCI60222201_s_atSNB7545.18082.530Details
BioGPS NCI60222201_s_atSR16.30982.530Details
BioGPS NCI60222201_s_atSW620123.14582.530Details
BioGPS NCI60222201_s_atT2457.02682.530Details
BioGPS NCI60222201_s_atT3M432.93882.530Details
BioGPS NCI60222201_s_atTK1041.77482.530Details
BioGPS NCI60222201_s_atU11829.15182.530Details
BioGPS NCI60222201_s_atU13831.02582.530Details
BioGPS NCI60222201_s_atU20S21.84482.530Details
BioGPS NCI60222201_s_atU25150.38682.530Details
BioGPS NCI60222201_s_atU8731.77082.530Details
BioGPS NCI60222201_s_atUACC25716.23582.530Details
BioGPS NCI60222201_s_atUACC6216.03682.530Details
BioGPS NCI60222201_s_atUO3176.74882.530Details
BioGPS NCI60222201_s_atZR75_132.81482.530Details
BioGPS NCI60222201_s_atastrocytes28.27782.530Details
BioGPS NCI60222201_s_athuh-764.73682.530Details