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Gene ID: 23581 | CASP14 Antibody Resource


CASP14 Antibody Resource
Gene Full Name: 
caspase 14, apoptosis-related cysteine peptidase
Uniprot: 
P31944
Protein Name: 
caspase-14
Nucleotide: 
NM_012114
Alias: 
Ensembl: 
ENSG00000105141
Location: 
19p13.1
HPRD: 
05788
NCBI Gene: 
23581
MIM: 
605848

Summary: 
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008]
Function: 
Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin .
Subcellular location: 
Cytoplasm. Nucleus .
PTM: 
Zymogen;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OASA07123 CASP14 antibody - C-terminal region (OASA07123) Human WB 0.1mg $380 Details
Polyclonal Antibody OASA07124 CASP14 antibody - C-terminal region (OASA07124) Human WB 50ug $280 Details
Polyclonal Antibody OAAB03950 CASP14 antibody - C-terminal region (OAAB03950) Human WB, ELISA 400ul $289 Details
Polyclonal Antibody ARP30491_P050 CASP14 Antibody (ARP30491_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP59073_P050 CASP14 Antibody (ARP59073_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP59074_P050 CASP14 Antibody (ARP59074_P050) Polyclonal Bovine, Dog, Horse, Human, Pig, Rabbit Not tested 50 ug $125 Details
Polyclonal Antibody OAEC01572 Caspase 14 (p10, Cleaved-Lys222) Antibody (OAEC01572) Human WB, ELISA 100ug $229 Details
Polyclonal Antibody OAGA00931 CASP14 antibody (OAGA00931) Polyclonal Human ICC/IF, WB 100 ul $340 Details
Polyclonal Antibody OAAF05337 CASP14 (p10, Cleaved-Lys222) Antibody (OAAF05337) Polyclonal Human WB, ELISA 100 ug $229 Details

Show all CASP14 antibodies


Product Images
CASP14 (p10, Cleaved-Lys222) Antibody (OAAF05337) in COLO, HepG2 cells using Western Blot

Sample Type: COLO, HepG2

Caspase 14 (p10, Cleaved-Lys222) Antibody (OAEC01572) in COLO cells using Western Blot

Sample Type: COLO


CASP14 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP59074 Bovine CASP14 antibody; Bos taurus CASP14 antibody G3X7H1 86.0%
ARP30491 Bovine CASP14 antibody; Bos taurus CASP14 antibody G3X7H1 79.0%
ARP59073 Bovine CASP14 antibody; Bos taurus CASP14 antibody G3X7H1 79.0%
ARP30491 Cat CASP14 antibody; Felis catus CASP14 antibody M3W8J6 93.0%
ARP59073 Cat CASP14 antibody; Felis catus CASP14 antibody M3W8J6 93.0%
ARP59074 Cat CASP14 antibody; Felis catus CASP14 antibody M3W8J6 86.0%
ARP30491 Chimpanzee CASP14 antibody; Pan troglodytes CASP14 antibody H2RFZ4 100.0%
ARP59073 Chimpanzee CASP14 antibody; Pan troglodytes CASP14 antibody H2RFZ4 100.0%
ARP59074 Chimpanzee CASP14 antibody; Pan troglodytes CASP14 antibody H2RFZ4 100.0%
ARP59074 Dog CASP14 antibody; Canis familiaris CASP14 antibody E2R0V4 93.0%
ARP59074 Dog CASP14 antibody; Canis familiaris CASP14 antibody F1PXJ6 93.0%
ARP30491 Dog CASP14 antibody; Canis familiaris CASP14 antibody E2R0V4 86.0%
ARP59073 Dog CASP14 antibody; Canis familiaris CASP14 antibody E2R0V4 86.0%
ARP59074 European domestic ferret CASP14 antibody; Mustela putorius furo CASP14 antibody M3YXJ8 93.0%
ARP30491 European domestic ferret CASP14 antibody; Mustela putorius furo CASP14 antibody M3YXJ8 86.0%
ARP59073 European domestic ferret CASP14 antibody; Mustela putorius furo CASP14 antibody M3YXJ8 86.0%
ARP59074 Giant panda CASP14 antibody; Ailuropoda melanoleuca CASP14 antibody G1L6V2 93.0%
ARP30491 Giant panda CASP14 antibody; Ailuropoda melanoleuca CASP14 antibody G1L6V2 86.0%
ARP59073 Giant panda CASP14 antibody; Ailuropoda melanoleuca CASP14 antibody G1L6V2 86.0%
ARP30491 Gray short-tailed opossum CASP14 antibody; Monodelphis domestica CASP14 antibody A5HAU7 79.0%
ARP30491 Gray short-tailed opossum CASP14 antibody; Monodelphis domestica CASP14 antibody F7FKU5 79.0%
ARP59074 Horse CASP14 antibody; Equus caballus CASP14 antibody F6RCN7 93.0%
ARP30491 Horse CASP14 antibody; Equus caballus CASP14 antibody F6RCN7 79.0%
ARP59073 Horse CASP14 antibody; Equus caballus CASP14 antibody F6RCN7 79.0%
ARP30491 Human CASP14 antibody; Homo sapiens CASP14 antibody P31944 100.0%
ARP59073 Human CASP14 antibody; Homo sapiens CASP14 antibody P31944 100.0%
ARP59074 Human CASP14 antibody; Homo sapiens CASP14 antibody P31944 100.0%
ARP59074 Human CASP14 antibody; Homo sapiens CASP14 antibody A9UFC0 100.0%
ARP30491 Human CASP14 antibody; Homo sapiens CASP14 antibody B2CIS9 100.0%
ARP59073 Human CASP14 antibody; Homo sapiens CASP14 antibody B2CIS9 100.0%
ARP59074 Human CASP14 antibody; Homo sapiens CASP14 antibody B2CIS9 100.0%
ARP30491 Human CASP14 antibody; Homo sapiens CASP14 antibody A9UFC0 93.0%
ARP59073 Human CASP14 antibody; Homo sapiens CASP14 antibody A9UFC0 93.0%
ARP30491 Mouse CASP14 antibody; Mus musculus CASP14 antibody O89094 79.0%
ARP59073 Mouse CASP14 antibody; Mus musculus CASP14 antibody O89094 79.0%
ARP30491 Mouse CASP14 antibody; Mus musculus CASP14 antibody Q542Q1 79.0%
ARP59073 Mouse CASP14 antibody; Mus musculus CASP14 antibody Q542Q1 79.0%
ARP59073 Pig CASP14 antibody; Sus scrofa CASP14 antibody M3VK04 83.0%
ARP59073 Pig CASP14 antibody; Sus scrofa CASP14 antibody F1SAN1 83.0%
ARP59074 Pig CASP14 antibody; Sus scrofa CASP14 antibody M3VK04 79.0%
ARP59074 Pig CASP14 antibody; Sus scrofa CASP14 antibody F1SAN1 79.0%
ARP59074 Rabbit CASP14 antibody; Oryctolagus cuniculus CASP14 antibody G1TXC0 79.0%
ARP30491 Rat CASP14 antibody; Rattus norvegicus CASP14 antibody D3ZZ65 86.0%
ARP59073 Rat CASP14 antibody; Rattus norvegicus CASP14 antibody D3ZZ65 86.0%
ARP59074 Rhesus macaque CASP14 antibody; Macaca mulatta CASP14 antibody F7GZH3 93.0%
ARP59073 Rhesus macaque CASP14 antibody; Macaca mulatta CASP14 antibody F7GZH3 86.0%
ARP30491 Rhesus macaque CASP14 antibody; Macaca mulatta CASP14 antibody F7GZH3 86.0%
ARP59074 Small-eared galago CASP14 antibody; Otolemur garnettii CASP14 antibody H0XJ66 100.0%
ARP30491 Small-eared galago CASP14 antibody; Otolemur garnettii CASP14 antibody H0XJ66 86.0%
ARP59073 Small-eared galago CASP14 antibody; Otolemur garnettii CASP14 antibody H0XJ66 86.0%
ARP59074 Sumatran orangutan CASP14 antibody; Pongo abelii CASP14 antibody H2NXV6 100.0%
ARP59074 White-tufted-ear marmoset CASP14 antibody; Callithrix jacchus CASP14 antibody F7HWS2 86.0%
ARP30491 White-tufted-ear marmoset CASP14 antibody; Callithrix jacchus CASP14 antibody F7HWS2 85.0%
ARP59073 White-tufted-ear marmoset CASP14 antibody; Callithrix jacchus CASP14 antibody F7HWS2 79.0%

Tissue & Cell Line Gene Expression Data