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Gene ID: 22900 | CARD8 Antibody Resource


CARD8 Antibody Resource
Gene Full Name: 
caspase recruitment domain family, member 8
Uniprot: 
Q9Y2G2
Protein Name: 
caspase recruitment domain-containing protein 8
Nucleotide: 
NM_001184902
Alias: 
NDPP;DACAR;DAKAR;NDPP1;TUCAN;CARDINAL;
Ensembl: 
ENSG00000105483
Location: 
19q13.33
HPRD: 
16425
NCBI Gene: 
22900
MIM: 
609051

Summary: 
The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
Function: 
Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases.
Subcellular location: 
Cytoplasm. Nucleus .
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB06463 CARD8 antibody - N-terminal region (OAAB06463) Human WB, FC, IHC 400ul $289 Details
Polyclonal Antibody OAPB00205 CARD8 Antibody (OAPB00205) Polyclonal Human ELISA, WB, ICC 0.1 mg $355 Details
Polyclonal Antibody ARP55119_P050 CARD8 Antibody - N-terminal region (ARP55119_P050) Polyclonal Human WB 50ug $289 Details
Polyclonal Antibody ARP55120_P050 CARD8 Antibody (ARP55120_P050) Polyclonal Human Not tested 50 ug $125 Details

Show all CARD8 antibodies


Product Images
CARD8 Antibody - N-terminal region (ARP55119_P050) in Human Fetal spleen cells using Western Blot

Sample Type: Human Fetal spleen


CARD8 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP55120 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7BPM5 100.0%
ARP55120 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody H2R317 100.0%
ARP55120 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7AMS9 93.0%
ARP55120 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7B4Y0 93.0%
ARP55120 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7BQJ8 93.0%
ARP55120 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7BVQ0 93.0%
ARP55119 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody H2R317 93.0%
ARP72828 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody H2R317 93.0%
ARP55119 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7AMS9 86.0%
ARP72828 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7AMS9 86.0%
ARP55119 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7B4Y0 86.0%
ARP72828 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7B4Y0 86.0%
ARP55119 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7BPM5 86.0%
ARP72828 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7BPM5 86.0%
ARP55119 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7BQJ8 86.0%
ARP72828 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7BQJ8 86.0%
ARP55119 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7BVQ0 86.0%
ARP72828 Chimpanzee CARD8 antibody; Pan troglodytes CARD8 antibody K7BVQ0 86.0%
ARP55120 Dog CARD8 antibody; Canis familiaris CARD8 antibody J9PB92 86.0%
ARP55120 Giant panda CARD8 antibody; Ailuropoda melanoleuca CARD8 antibody G1M975 79.0%
ARP55119 Human CARD8 antibody; Homo sapiens CARD8 antibody I6L9C6 100.0%
ARP55120 Human CARD8 antibody; Homo sapiens CARD8 antibody I6L9C6 100.0%
ARP72828 Human CARD8 antibody; Homo sapiens CARD8 antibody I6L9C6 100.0%
ARP55119 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2-2 100.0%
ARP55120 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2-2 100.0%
ARP72828 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2-2 100.0%
ARP55119 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2-3 100.0%
ARP55120 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2-3 100.0%
ARP72828 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2-3 100.0%
ARP55119 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2-4 100.0%
ARP55120 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2-4 100.0%
ARP72828 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2-4 100.0%
ARP55119 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2-5 100.0%
ARP55120 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2-5 100.0%
ARP72828 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2-5 100.0%
ARP55119 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2 100.0%
ARP55120 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2 100.0%
ARP72828 Human CARD8 antibody; Homo sapiens CARD8 antibody Q9Y2G2 100.0%
ARP55119 Human CARD8 antibody; Homo sapiens CARD8 antibody B5KVR7 100.0%
ARP55120 Human CARD8 antibody; Homo sapiens CARD8 antibody B5KVR7 100.0%
ARP72828 Human CARD8 antibody; Homo sapiens CARD8 antibody B5KVR7 100.0%
ARP55119 Human CARD8 antibody; Homo sapiens CARD8 antibody B5KVR8 100.0%
ARP55120 Human CARD8 antibody; Homo sapiens CARD8 antibody B5KVR8 100.0%
ARP72828 Human CARD8 antibody; Homo sapiens CARD8 antibody B5KVR8 100.0%
ARP55120 Human CARD8 antibody; Homo sapiens CARD8 antibody B7Z7N9 100.0%
ARP55119 Human CARD8 antibody; Homo sapiens CARD8 antibody E5RHJ3 100.0%
ARP72828 Human CARD8 antibody; Homo sapiens CARD8 antibody E5RHJ3 100.0%
ARP55120 Rhesus macaque CARD8 antibody; Macaca mulatta CARD8 antibody F7H560 86.0%
ARP55119 Rhesus macaque CARD8 antibody; Macaca mulatta CARD8 antibody F6XJ05 79.0%
ARP55119 Rhesus macaque CARD8 antibody; Macaca mulatta CARD8 antibody F7H560 79.0%
ARP55120 Sumatran orangutan CARD8 antibody; Pongo abelii CARD8 antibody H2NZF5 100.0%
ARP55119 Sumatran orangutan CARD8 antibody; Pongo abelii CARD8 antibody Q5RAV7 93.0%
ARP55120 Sumatran orangutan CARD8 antibody; Pongo abelii CARD8 antibody Q5RAV7 93.0%
ARP72828 Sumatran orangutan CARD8 antibody; Pongo abelii CARD8 antibody Q5RAV7 93.0%
ARP55119 Sumatran orangutan CARD8 antibody; Pongo abelii CARD8 antibody H2NZF5 79.0%
ARP55120 White-tufted-ear marmoset CARD8 antibody; Callithrix jacchus CARD8 antibody F6PN09 86.0%
ARP55120 White-tufted-ear marmoset CARD8 antibody; Callithrix jacchus CARD8 antibody F6PXA2 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas204950_at721_B_lymphoblasts9.40014.130Details
BioGPS Gene Atlas204950_atAdipocyte5.35014.130Details
BioGPS Gene Atlas204950_atAdrenalCortex6.50014.130Details
BioGPS Gene Atlas204950_atAdrenalgland4.40014.130Details
BioGPS Gene Atlas204950_atAmygdala5.40014.130Details
BioGPS Gene Atlas204950_atAppendix6.65014.130Details
BioGPS Gene Atlas204950_atAtrioventricularNode5.30014.130Details
BioGPS Gene Atlas204950_atBDCA4+_DentriticCells53.25014.130Details
BioGPS Gene Atlas204950_atBonemarrow6.10014.130Details
BioGPS Gene Atlas204950_atBronchialEpithelialCells5.00014.130Details
BioGPS Gene Atlas204950_atCD105+_Endothelial35.80014.130Details
BioGPS Gene Atlas204950_atCD14+_Monocytes37.95014.130Details
BioGPS Gene Atlas204950_atCD19+_BCells(neg._sel.)18.05014.130Details
BioGPS Gene Atlas204950_atCD33+_Myeloid154.90014.130Details
BioGPS Gene Atlas204950_atCD34+83.85014.130Details
BioGPS Gene Atlas204950_atCD4+_Tcells165.75014.130Details
BioGPS Gene Atlas204950_atCD56+_NKCells41.70014.130Details
BioGPS Gene Atlas204950_atCD71+_EarlyErythroid10.15014.130Details
BioGPS Gene Atlas204950_atCD8+_Tcells120.95014.130Details
BioGPS Gene Atlas204950_atCardiacMyocytes7.50014.130Details
BioGPS Gene Atlas204950_atCaudatenucleus4.85014.130Details
BioGPS Gene Atlas204950_atCerebellum4.35014.130Details
BioGPS Gene Atlas204950_atCerebellumPeduncles6.25014.130Details
BioGPS Gene Atlas204950_atCiliaryGanglion5.45014.130Details
BioGPS Gene Atlas204950_atCingulateCortex5.45014.130Details
BioGPS Gene Atlas204950_atColorectaladenocarcinoma5.35014.130Details
BioGPS Gene Atlas204950_atDorsalRootGanglion5.25014.130Details
BioGPS Gene Atlas204950_atFetalThyroid5.35014.130Details
BioGPS Gene Atlas204950_atFetalbrain5.15014.130Details
BioGPS Gene Atlas204950_atFetalliver4.75014.130Details
BioGPS Gene Atlas204950_atFetallung4.35014.130Details
BioGPS Gene Atlas204950_atGlobusPallidus3.85014.130Details
BioGPS Gene Atlas204950_atHeart7.50014.130Details
BioGPS Gene Atlas204950_atHypothalamus5.75014.130Details
BioGPS Gene Atlas204950_atKidney4.10014.130Details
BioGPS Gene Atlas204950_atLeukemia_chronicMyelogenousK-5624.75014.130Details
BioGPS Gene Atlas204950_atLeukemia_promyelocytic-HL-604.70014.130Details
BioGPS Gene Atlas204950_atLeukemialymphoblastic(MOLT-4)4.30014.130Details
BioGPS Gene Atlas204950_atLiver7.50014.130Details
BioGPS Gene Atlas204950_atLung5.85014.130Details
BioGPS Gene Atlas204950_atLymphnode21.70014.130Details
BioGPS Gene Atlas204950_atLymphoma_burkitts(Daudi)6.40014.130Details
BioGPS Gene Atlas204950_atLymphoma_burkitts(Raji)8.20014.130Details
BioGPS Gene Atlas204950_atMedullaOblongata4.80014.130Details
BioGPS Gene Atlas204950_atOccipitalLobe4.65014.130Details
BioGPS Gene Atlas204950_atOlfactoryBulb4.10014.130Details
BioGPS Gene Atlas204950_atOvary3.90014.130Details
BioGPS Gene Atlas204950_atPancreas4.30014.130Details
BioGPS Gene Atlas204950_atPancreaticIslet5.75014.130Details
BioGPS Gene Atlas204950_atParietalLobe5.90014.130Details
BioGPS Gene Atlas204950_atPituitary6.15014.130Details
BioGPS Gene Atlas204950_atPlacenta5.40014.130Details
BioGPS Gene Atlas204950_atPons5.25014.130Details
BioGPS Gene Atlas204950_atPrefrontalCortex6.30014.130Details
BioGPS Gene Atlas204950_atProstate6.25014.130Details
BioGPS Gene Atlas204950_atSalivarygland4.70014.130Details
BioGPS Gene Atlas204950_atSkeletalMuscle7.75014.130Details
BioGPS Gene Atlas204950_atSkin6.55014.130Details
BioGPS Gene Atlas204950_atSmoothMuscle5.75014.130Details
BioGPS Gene Atlas204950_atSpinalcord5.65014.130Details
BioGPS Gene Atlas204950_atSubthalamicNucleus4.85014.130Details
BioGPS Gene Atlas204950_atSuperiorCervicalGanglion8.45014.130Details
BioGPS Gene Atlas204950_atTemporalLobe5.05014.130Details
BioGPS Gene Atlas204950_atTestis4.55014.130Details
BioGPS Gene Atlas204950_atTestisGermCell6.15014.130Details
BioGPS Gene Atlas204950_atTestisIntersitial4.90014.130Details
BioGPS Gene Atlas204950_atTestisLeydigCell5.85014.130Details
BioGPS Gene Atlas204950_atTestisSeminiferousTubule4.55014.130Details
BioGPS Gene Atlas204950_atThalamus5.10014.130Details
BioGPS Gene Atlas204950_atThymus7.15014.130Details
BioGPS Gene Atlas204950_atThyroid6.40014.130Details
BioGPS Gene Atlas204950_atTongue5.60014.130Details
BioGPS Gene Atlas204950_atTonsil9.50014.130Details
BioGPS Gene Atlas204950_atTrachea4.45014.130Details
BioGPS Gene Atlas204950_atTrigeminalGanglion6.50014.130Details
BioGPS Gene Atlas204950_atUterus4.70014.130Details
BioGPS Gene Atlas204950_atUterusCorpus7.90014.130Details
BioGPS Gene Atlas204950_atWholeBlood28.80014.130Details
BioGPS Gene Atlas204950_atWholebrain4.15014.130Details
BioGPS Gene Atlas204950_atcolon5.30014.130Details
BioGPS Gene Atlas204950_atpineal_day13.92014.130Details
BioGPS Gene Atlas204950_atpineal_night11.40014.130Details
BioGPS Gene Atlas204950_atretina8.50014.130Details
BioGPS Gene Atlas204950_atsmall_intestine5.00014.130Details
BioGPS NCI60204950_at7865.4355.690Details
BioGPS NCI60204950_atA1724.9385.690Details
BioGPS NCI60204950_atA2045.7555.690Details
BioGPS NCI60204950_atA3615.2745.690Details
BioGPS NCI60204950_atA4985.1075.690Details
BioGPS NCI60204950_atA5495.3505.690Details
BioGPS NCI60204950_atACC35.3165.690Details
BioGPS NCI60204950_atACHN4.6815.690Details
BioGPS NCI60204950_atALVA316.7745.690Details
BioGPS NCI60204950_atCAKI15.5385.690Details
BioGPS NCI60204950_atCCRT CEM11.6295.690Details
BioGPS NCI60204950_atCOLO2055.0635.690Details
BioGPS NCI60204950_atDLD15.0485.690Details
BioGPS NCI60204950_atDU1454.6905.690Details
BioGPS NCI60204950_atEKVX4.8675.690Details
BioGPS NCI60204950_atGM1335.6585.690Details
BioGPS NCI60204950_atGM16006.4005.690Details
BioGPS NCI60204950_atGM23135.7035.690Details
BioGPS NCI60204950_atGM23455.6115.690Details
BioGPS NCI60204950_atGM24936.3705.690Details
BioGPS NCI60204950_atGM979.0955.690Details
BioGPS NCI60204950_atHCC29984.9655.690Details
BioGPS NCI60204950_atHCT1165.1915.690Details
BioGPS NCI60204950_atHCT154.7825.690Details
BioGPS NCI60204950_atHEK 293 T-rex5.7055.690Details
BioGPS NCI60204950_atHEK 293T5.2735.690Details
BioGPS NCI60204950_atHEK2937.0665.690Details
BioGPS NCI60204950_atHELA4.7585.690Details
BioGPS NCI60204950_atHEPG25.2405.690Details
BioGPS NCI60204950_atHL605.5295.690Details
BioGPS NCI60204950_atHOP626.9775.690Details
BioGPS NCI60204950_atHOP925.0125.690Details
BioGPS NCI60204950_atHS578T5.0675.690Details
BioGPS NCI60204950_atHSG4.9935.690Details
BioGPS NCI60204950_atHT10805.0705.690Details
BioGPS NCI60204950_atHT295.8465.690Details
BioGPS NCI60204950_atIGROV16.0965.690Details
BioGPS NCI60204950_atIOSE805.1695.690Details
BioGPS NCI60204950_atJURKAT8.5315.690Details
BioGPS NCI60204950_atK5625.9815.690Details
BioGPS NCI60204950_atKM126.0235.690Details
BioGPS NCI60204950_atLN185.8235.690Details
BioGPS NCI60204950_atLNCAP5.2455.690Details
BioGPS NCI60204950_atLOX IMVI5.2425.690Details
BioGPS NCI60204950_atM1410.9715.690Details
BioGPS NCI60204950_atMALME 3M5.6975.690Details
BioGPS NCI60204950_atMCF74.8735.690Details
BioGPS NCI60204950_atMD MB2316.0075.690Details
BioGPS NCI60204950_atMDA MB4355.7745.690Details
BioGPS NCI60204950_atMOLT45.5145.690Details
BioGPS NCI60204950_atNCI 4605.5865.690Details
BioGPS NCI60204950_atNCI H2265.6525.690Details
BioGPS NCI60204950_atNCI H235.1685.690Details
BioGPS NCI60204950_atNCI H322M5.1465.690Details
BioGPS NCI60204950_atNCVADR RES4.7615.690Details
BioGPS NCI60204950_atOVCAR35.3045.690Details
BioGPS NCI60204950_atOVCAR45.1015.690Details
BioGPS NCI60204950_atOVCAR54.9065.690Details
BioGPS NCI60204950_atOVCAR85.1175.690Details
BioGPS NCI60204950_atPANC15.2045.690Details
BioGPS NCI60204950_atRL76.4285.690Details
BioGPS NCI60204950_atRPMI 82265.3745.690Details
BioGPS NCI60204950_atRS118465.6445.690Details
BioGPS NCI60204950_atRXF3935.1795.690Details
BioGPS NCI60204950_atSAOS25.2475.690Details
BioGPS NCI60204950_atSF2685.1715.690Details
BioGPS NCI60204950_atSF2955.0275.690Details
BioGPS NCI60204950_atSF5395.6565.690Details
BioGPS NCI60204950_atSHSYSY+RA5.0025.690Details
BioGPS NCI60204950_atSHSYSY-RA5.0495.690Details
BioGPS NCI60204950_atSKMEL25.1725.690Details
BioGPS NCI60204950_atSKMEL287.7085.690Details
BioGPS NCI60204950_atSKMEL55.1335.690Details
BioGPS NCI60204950_atSKOV35.3235.690Details
BioGPS NCI60204950_atSN12C5.1385.690Details
BioGPS NCI60204950_atSNB194.5765.690Details
BioGPS NCI60204950_atSNB755.0265.690Details
BioGPS NCI60204950_atSR5.9835.690Details
BioGPS NCI60204950_atSW6205.3465.690Details
BioGPS NCI60204950_atT245.2585.690Details
BioGPS NCI60204950_atT3M45.5245.690Details
BioGPS NCI60204950_atTK105.1085.690Details
BioGPS NCI60204950_atU1185.0595.690Details
BioGPS NCI60204950_atU1384.7905.690Details
BioGPS NCI60204950_atU20S10.7265.690Details
BioGPS NCI60204950_atU2515.0195.690Details
BioGPS NCI60204950_atU875.0325.690Details
BioGPS NCI60204950_atUACC2575.0905.690Details
BioGPS NCI60204950_atUACC625.4345.690Details
BioGPS NCI60204950_atUO314.9565.690Details
BioGPS NCI60204950_atZR75_15.4625.690Details
BioGPS NCI60204950_atastrocytes5.4185.690Details
BioGPS NCI60204950_athuh-76.0585.690Details