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Gene ID: 114769 | CARD16 Antibody Resource


CARD16 Antibody Resource
Gene Full Name: 
caspase recruitment domain family, member 16
Uniprot: 
Q5EG05
Protein Name: 
caspase recruitment domain-containing protein 16
Nucleotide: 
NM_001017534
Alias: 
COP;COP1;PSEUDO-ICE;
Ensembl: 
ENSG00000204397
Location: 
HPRD: 
16740
NCBI Gene: 
114769
MIM: 

Summary: 
Function: 
Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
Subcellular location: 
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAEB00579 Goat Anti-COP1 / PSEUDO-ICE (Isofom 2) Antibody (OAEB00579) Human ELISA 0.1mg $229 Details
Polyclonal Antibody OAAB07574 COP1 antibody - N - terminal region (OAAB07574) Human FC, WB 400ul $289 Details

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Product Images
COP1 antibody - N - terminal region (OAAB07574) in A549 cells using Flow Cytometry

Sample Type: A549

COP1 antibody - N - terminal region (OAAB07574) in CEM, A549 cells using Western Blot

Sample Type: CEM, A549


CARD16 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP69170 Chimpanzee CARD16 antibody; Pan troglodytes CARD16 antibody H2R501 93.0%
ARP58983 Chimpanzee CARD16 antibody; Pan troglodytes CARD16 antibody H2R501 86.0%
ARP69170 Human CARD16 antibody; Homo sapiens CARD16 antibody E9PQW1 100.0%
ARP69170 Human CARD16 antibody; Homo sapiens CARD16 antibody Q5EG05-2 100.0%
ARP69170 Human CARD16 antibody; Homo sapiens CARD16 antibody Q5EG05 100.0%
ARP58983 Human CARD16 antibody; Homo sapiens CARD16 antibody E9PQW1 93.0%
ARP58983 Human CARD16 antibody; Homo sapiens CARD16 antibody Q5EG05-2 93.0%
ARP58983 Human CARD16 antibody; Homo sapiens CARD16 antibody Q5EG05 93.0%
ARP69170 Rhesus macaque CARD16 antibody; Macaca mulatta CARD16 antibody H9F298 86.0%
ARP58983 Rhesus macaque CARD16 antibody; Macaca mulatta CARD16 antibody H9F298 85.0%
ARP61219 Rhesus macaque CARD16 antibody; Macaca mulatta CARD16 antibody H9F298 85.0%

Tissue & Cell Line Gene Expression Data