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Gene ID: 814 | CAMK4 Antibody Resource


CAMK4 Antibody Resource
Gene Full Name: 
calcium/calmodulin-dependent protein kinase IV
Uniprot: 
Q16566
Protein Name: 
calcium/calmodulin-dependent protein kinase type IV
Nucleotide: 
NM_001744
Alias: 
IV;caMK;CaMK IV;CaMK-GR;
Ensembl: 
Location: 
5q21.3
HPRD: 
07169
NCBI Gene: 
814
MIM: 
114080

Summary: 
The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. [provided by RefSeq, Jul 2008]
Function: 
Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phosphorylation, the activity of several transcription activators, such as CREB1, MEF2D, JUN and RORA, which play pivotal roles in immune response, inflammation, and memory consolidation. In the thymus, regulates the CD4+/CD8+ double positive thymocytes selection threshold during T-cell ontogeny. In CD4 memory T-cells, is required to link T-cell antigen receptor (TCR) signaling to the production of IL2, IFNG and IL4 (through the regulation of CREB and MEF2). Regulates the differentiation and survival phases of osteoclasts and dendritic cells (DCs). Mediates DCs survival by linking TLR4 and the regulation of temporal expression of BCL2. Phosphorylates the transcription activator CREB1 on 'Ser-133' in hippocampal neuron nuclei and contribute to memory consolidation and long term potentiation (LTP) in the hippocampus. Can activate the MAP kinases MAPK1/ERK2, MAPK8/JNK1 and MAPK14/p38 and stimulate transcription through the phosphorylation of ELK1 and ATF2. Can also phosphorylate in vitro CREBBP, PRM2, MEF2A and STMN1/OP18.
Subcellular location: 
Cytoplasm. Nucleus. Note: Localized in hippocampal neuron nuclei. In spermatids, associated with chromatin and nuclear matrix .
PTM: 
Glycoprotein;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP37025_T100 CAMK4 antibody - C-terminal region (ARP37025_T100) Polyclonal Mouse WB 100ug $229 Details
Polyclonal Antibody ARP61352_P050 CAMK4 antibody - C-terminal region (ARP61352_P050) Polyclonal Horse WB 50ug $289 Details
Polyclonal Antibody ARP61351_P050 CAMK4 antibody - N-terminal region (ARP61351_P050) Dog, Horse, Human, Mouse, Pig, Rat, Zebrafish WB 50ug $289 Details
Polyclonal Antibody OAAB04185 CAMK4 antibody - center region (OAAB04185) Human WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP37026_P050 Camk4 Antibody - C-terminal region (ARP37026_P050) Mouse; Human WB 50ug $289 Details
Polyclonal Antibody OAAB11469 Mouse Camk4 antibody - C - terminal region (OAAB11469) Mouse WB 400ul $289 Details
Polyclonal Antibody OAAB16988 CAMKIV (CAMK4) antibody - C - terminal region (OAAB16988) Human; Mouse WB 400ul $289 Details
Polyclonal Antibody OAAF00976 CaMK4 Antibody (OAAF00976) Polyclonal Human, Mouse, Rat WB, IHC, IF, ELISA 100 ug $289 Details

Show all CAMK4 antibodies


Product Images
CAMK4 antibody - C-terminal region (ARP37025_T100) in Human Thymus cells using Western Blot

Sample Type: Human Thymus

Camk4 Antibody - C-terminal region (ARP37026_P050) in Mouse Testis cells using Western Blot

Sample Type: Mouse Testis

CAMK4 antibody - N-terminal region (ARP61351_P050) in Human ACHN cells using Western Blot

Sample Type: Human ACHN

CAMK4 antibody - C-terminal region (ARP61352_P050) in Human HepG2 cells using Western Blot

Sample Type: Human HepG2

Mouse Camk4 antibody - C - terminal region (OAAB11469) in Mouse Heart cells using Western Blot

Sample Type: Mouse Heart

CaMK4 Antibody (OAAF00976) in HepG2 cells using Immunofluorescence

Sample Type: HepG2

CaMK4 Antibody (OAAF00976) in Human brain cells using Immunohistochemistry

Sample Type: Human brain

CaMK4 Antibody (OAAF00976) in K562 cells using Western Blot

Sample Type: K562


CAMK4 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP61351 African elephant CAMK4 antibody; Loxodonta africana CAMK4 antibody G3SYI8 100.0%
ARP61352 African elephant CAMK4 antibody; Loxodonta africana CAMK4 antibody G3SYI8 86.0%
ARP61352 African elephant CAMK4 antibody; Loxodonta africana CAMK4 antibody G3UBW4 86.0%
ARP61351 Cat CAMK4 antibody; Felis catus CAMK4 antibody M3VWV3 100.0%
ARP61351 Chimpanzee CAMK4 antibody; Pan troglodytes CAMK4 antibody H2QRB1 100.0%
ARP61352 Chimpanzee CAMK4 antibody; Pan troglodytes CAMK4 antibody H2QRB1 100.0%
ARP61351 Chinese softshell turtle CAMK4 antibody; Pelodiscus sinensis CAMK4 antibody K7G0Z5 86.0%
ARP61351 Collared flycatcher CAMK4 antibody; Ficedula albicollis CAMK4 antibody U3K7Z2 86.0%
ARP61351 Dog CAMK4 antibody; Canis familiaris CAMK4 antibody E2QWL2 100.0%
ARP61351 Duckbill platypus CAMK4 antibody; Ornithorhynchus anatinus CAMK4 antibody F6W090 86.0%
ARP61351 Giant panda CAMK4 antibody; Ailuropoda melanoleuca CAMK4 antibody G1M258 100.0%
ARP61351 Giant panda CAMK4 antibody; Ailuropoda melanoleuca CAMK4 antibody G1M260 100.0%
ARP61351 Gray short-tailed opossum CAMK4 antibody; Monodelphis domestica CAMK4 antibody F7EIH3 93.0%
ARP61351 Horse CAMK4 antibody; Equus caballus CAMK4 antibody F6WUG4 100.0%
ARP61352 Horse CAMK4 antibody; Equus caballus CAMK4 antibody F6WUG4 79.0%
ARP61351 Human CAMK4 antibody; Homo sapiens CAMK4 antibody D6RCD6 100.0%
ARP61351 Human CAMK4 antibody; Homo sapiens CAMK4 antibody D6RE65 100.0%
ARP61351 Human CAMK4 antibody; Homo sapiens CAMK4 antibody D6REY7 100.0%
ARP61351 Human CAMK4 antibody; Homo sapiens CAMK4 antibody Q16566 100.0%
ARP61352 Human CAMK4 antibody; Homo sapiens CAMK4 antibody Q16566 100.0%
ARP37025 Mouse CAMK4 antibody; Mus musculus CAMK4 antibody P08414 100.0%
ARP37026 Mouse CAMK4 antibody; Mus musculus CAMK4 antibody P08414 100.0%
ARP61351 Mouse CAMK4 antibody; Mus musculus CAMK4 antibody P08414 100.0%
ARP37025 Mouse CAMK4 antibody; Mus musculus CAMK4 antibody Q8BGR3 100.0%
ARP37026 Mouse CAMK4 antibody; Mus musculus CAMK4 antibody Q8BGR3 100.0%
ARP61351 Mouse CAMK4 antibody; Mus musculus CAMK4 antibody Q8BGR3 100.0%
ARP61351 Northern white-cheeked gibbon CAMK4 antibody; Nomascus leucogenys CAMK4 antibody G1RL45 100.0%
ARP61352 Northern white-cheeked gibbon CAMK4 antibody; Nomascus leucogenys CAMK4 antibody G1RL45 93.0%
ARP61351 Rat CAMK4 antibody; Rattus norvegicus CAMK4 antibody P13234 100.0%
ARP61352 Rhesus macaque CAMK4 antibody; Macaca mulatta CAMK4 antibody H9ER84 100.0%
ARP61351 Rhesus macaque CAMK4 antibody; Macaca mulatta CAMK4 antibody H9ER84 100.0%
ARP61352 Small-eared galago CAMK4 antibody; Otolemur garnettii CAMK4 antibody H0WWM2 86.0%
ARP61351 Sumatran orangutan CAMK4 antibody; Pongo abelii CAMK4 antibody H2PG90 100.0%
ARP61352 Sumatran orangutan CAMK4 antibody; Pongo abelii CAMK4 antibody H2PG90 100.0%
ARP61351 Thirteen-lined ground squirrel CAMK4 antibody; Spermophilus tridecemlineatus CAMK4 antibody I3M4D4 100.0%
ARP61351 Three-spined stickleback CAMK4 antibody; Gasterosteus aculeatus CAMK4 antibody G3PK53 79.0%
ARP61351 Three-spined stickleback CAMK4 antibody; Gasterosteus aculeatus CAMK4 antibody G3PK58 79.0%
ARP61351 Western clawed frog CAMK4 antibody; Xenopus tropicalis CAMK4 antibody F6XL87 79.0%
ARP61351 White-tufted-ear marmoset CAMK4 antibody; Callithrix jacchus CAMK4 antibody F6WCB6 100.0%
ARP61352 White-tufted-ear marmoset CAMK4 antibody; Callithrix jacchus CAMK4 antibody F6WCB6 93.0%
ARP61351 Zebrafish CAMK4 antibody; Danio rerio CAMK4 antibody Q568I9 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas210349_at721_B_lymphoblasts7.6006.380Details
BioGPS Gene Atlas210349_atAdipocyte5.7506.380Details
BioGPS Gene Atlas210349_atAdrenalCortex6.4006.380Details
BioGPS Gene Atlas210349_atAdrenalgland5.0506.380Details
BioGPS Gene Atlas210349_atAmygdala6.9506.380Details
BioGPS Gene Atlas210349_atAppendix6.1006.380Details
BioGPS Gene Atlas210349_atAtrioventricularNode6.6006.380Details
BioGPS Gene Atlas210349_atBDCA4+_DentriticCells6.1506.380Details
BioGPS Gene Atlas210349_atBonemarrow6.1006.380Details
BioGPS Gene Atlas210349_atBronchialEpithelialCells5.6006.380Details
BioGPS Gene Atlas210349_atCD105+_Endothelial5.9506.380Details
BioGPS Gene Atlas210349_atCD14+_Monocytes6.2506.380Details
BioGPS Gene Atlas210349_atCD19+_BCells(neg._sel.)6.2006.380Details
BioGPS Gene Atlas210349_atCD33+_Myeloid7.3006.380Details
BioGPS Gene Atlas210349_atCD34+7.1506.380Details
BioGPS Gene Atlas210349_atCD4+_Tcells8.2006.380Details
BioGPS Gene Atlas210349_atCD56+_NKCells6.8006.380Details
BioGPS Gene Atlas210349_atCD71+_EarlyErythroid5.5506.380Details
BioGPS Gene Atlas210349_atCD8+_Tcells12.9506.380Details
BioGPS Gene Atlas210349_atCardiacMyocytes7.8506.380Details
BioGPS Gene Atlas210349_atCaudatenucleus5.3506.380Details
BioGPS Gene Atlas210349_atCerebellum4.8506.380Details
BioGPS Gene Atlas210349_atCerebellumPeduncles9.8006.380Details
BioGPS Gene Atlas210349_atCiliaryGanglion6.3006.380Details
BioGPS Gene Atlas210349_atCingulateCortex6.3506.380Details
BioGPS Gene Atlas210349_atColorectaladenocarcinoma5.8506.380Details
BioGPS Gene Atlas210349_atDorsalRootGanglion4.8006.380Details
BioGPS Gene Atlas210349_atFetalThyroid7.1506.380Details
BioGPS Gene Atlas210349_atFetalbrain5.8506.380Details
BioGPS Gene Atlas210349_atFetalliver5.3506.380Details
BioGPS Gene Atlas210349_atFetallung4.8006.380Details
BioGPS Gene Atlas210349_atGlobusPallidus4.5006.380Details
BioGPS Gene Atlas210349_atHeart7.9506.380Details
BioGPS Gene Atlas210349_atHypothalamus6.3006.380Details
BioGPS Gene Atlas210349_atKidney4.9506.380Details
BioGPS Gene Atlas210349_atLeukemia_chronicMyelogenousK-5625.4006.380Details
BioGPS Gene Atlas210349_atLeukemia_promyelocytic-HL-605.3006.380Details
BioGPS Gene Atlas210349_atLeukemialymphoblastic(MOLT-4)4.7506.380Details
BioGPS Gene Atlas210349_atLiver8.1006.380Details
BioGPS Gene Atlas210349_atLung6.2506.380Details
BioGPS Gene Atlas210349_atLymphnode4.8006.380Details
BioGPS Gene Atlas210349_atLymphoma_burkitts(Daudi)7.7506.380Details
BioGPS Gene Atlas210349_atLymphoma_burkitts(Raji)8.5506.380Details
BioGPS Gene Atlas210349_atMedullaOblongata5.4506.380Details
BioGPS Gene Atlas210349_atOccipitalLobe5.1506.380Details
BioGPS Gene Atlas210349_atOlfactoryBulb4.7006.380Details
BioGPS Gene Atlas210349_atOvary4.0506.380Details
BioGPS Gene Atlas210349_atPancreas4.8506.380Details
BioGPS Gene Atlas210349_atPancreaticIslet6.3506.380Details
BioGPS Gene Atlas210349_atParietalLobe6.5006.380Details
BioGPS Gene Atlas210349_atPituitary6.8506.380Details
BioGPS Gene Atlas210349_atPlacenta5.8006.380Details
BioGPS Gene Atlas210349_atPons5.7506.380Details
BioGPS Gene Atlas210349_atPrefrontalCortex6.9006.380Details
BioGPS Gene Atlas210349_atProstate6.7506.380Details
BioGPS Gene Atlas210349_atSalivarygland4.7006.380Details
BioGPS Gene Atlas210349_atSkeletalMuscle7.2006.380Details
BioGPS Gene Atlas210349_atSkin4.7506.380Details
BioGPS Gene Atlas210349_atSmoothMuscle6.6506.380Details
BioGPS Gene Atlas210349_atSpinalcord6.6506.380Details
BioGPS Gene Atlas210349_atSubthalamicNucleus5.5006.380Details
BioGPS Gene Atlas210349_atSuperiorCervicalGanglion8.4506.380Details
BioGPS Gene Atlas210349_atTemporalLobe5.5006.380Details
BioGPS Gene Atlas210349_atTestis9.8506.380Details
BioGPS Gene Atlas210349_atTestisGermCell6.6006.380Details
BioGPS Gene Atlas210349_atTestisIntersitial11.9506.380Details
BioGPS Gene Atlas210349_atTestisLeydigCell7.2506.380Details
BioGPS Gene Atlas210349_atTestisSeminiferousTubule5.8006.380Details
BioGPS Gene Atlas210349_atThalamus6.0506.380Details
BioGPS Gene Atlas210349_atThymus4.9506.380Details
BioGPS Gene Atlas210349_atThyroid7.3006.380Details
BioGPS Gene Atlas210349_atTongue6.3506.380Details
BioGPS Gene Atlas210349_atTonsil5.8006.380Details
BioGPS Gene Atlas210349_atTrachea4.9006.380Details
BioGPS Gene Atlas210349_atTrigeminalGanglion6.4006.380Details
BioGPS Gene Atlas210349_atUterus4.7006.380Details
BioGPS Gene Atlas210349_atUterusCorpus5.5006.380Details
BioGPS Gene Atlas210349_atWholeBlood6.2006.380Details
BioGPS Gene Atlas210349_atWholebrain4.9006.380Details
BioGPS Gene Atlas210349_atcolon5.8006.380Details
BioGPS Gene Atlas210349_atpineal_day7.1806.380Details
BioGPS Gene Atlas210349_atpineal_night7.1006.380Details
BioGPS Gene Atlas210349_atretina7.0506.380Details
BioGPS Gene Atlas210349_atsmall_intestine5.5006.380Details
BioGPS NCI60210349_at7864.5454.410Details
BioGPS NCI60210349_atA1724.1024.410Details
BioGPS NCI60210349_atA2044.3044.410Details
BioGPS NCI60210349_atA3614.4334.410Details
BioGPS NCI60210349_atA4984.3174.410Details
BioGPS NCI60210349_atA5494.3964.410Details
BioGPS NCI60210349_atACC34.6114.410Details
BioGPS NCI60210349_atACHN4.0504.410Details
BioGPS NCI60210349_atALVA314.6924.410Details
BioGPS NCI60210349_atCAKI14.5724.410Details
BioGPS NCI60210349_atCCRT CEM5.1384.410Details
BioGPS NCI60210349_atCOLO2054.3764.410Details
BioGPS NCI60210349_atDLD14.2404.410Details
BioGPS NCI60210349_atDU1454.1454.410Details
BioGPS NCI60210349_atEKVX4.1214.410Details
BioGPS NCI60210349_atGM1334.4894.410Details
BioGPS NCI60210349_atGM16004.5854.410Details
BioGPS NCI60210349_atGM23134.4354.410Details
BioGPS NCI60210349_atGM23454.3534.410Details
BioGPS NCI60210349_atGM24934.8674.410Details
BioGPS NCI60210349_atGM975.5884.410Details
BioGPS NCI60210349_atHCC29983.9154.410Details
BioGPS NCI60210349_atHCT1164.3704.410Details
BioGPS NCI60210349_atHCT154.0614.410Details
BioGPS NCI60210349_atHEK 293 T-rex4.6154.410Details
BioGPS NCI60210349_atHEK 293T4.3824.410Details
BioGPS NCI60210349_atHEK2934.3564.410Details
BioGPS NCI60210349_atHELA4.0374.410Details
BioGPS NCI60210349_atHEPG24.3144.410Details
BioGPS NCI60210349_atHL604.8424.410Details
BioGPS NCI60210349_atHOP624.3684.410Details
BioGPS NCI60210349_atHOP924.1694.410Details
BioGPS NCI60210349_atHS578T4.2724.410Details
BioGPS NCI60210349_atHSG4.1374.410Details
BioGPS NCI60210349_atHT10804.2884.410Details
BioGPS NCI60210349_atHT294.7384.410Details
BioGPS NCI60210349_atIGROV14.2774.410Details
BioGPS NCI60210349_atIOSE804.3174.410Details
BioGPS NCI60210349_atJURKAT6.9684.410Details
BioGPS NCI60210349_atK5624.7204.410Details
BioGPS NCI60210349_atKM124.5944.410Details
BioGPS NCI60210349_atLN184.0584.410Details
BioGPS NCI60210349_atLNCAP4.3704.410Details
BioGPS NCI60210349_atLOX IMVI4.3254.410Details
BioGPS NCI60210349_atM144.3084.410Details
BioGPS NCI60210349_atMALME 3M4.6874.410Details
BioGPS NCI60210349_atMCF74.1724.410Details
BioGPS NCI60210349_atMD MB2314.4484.410Details
BioGPS NCI60210349_atMDA MB4354.7324.410Details
BioGPS NCI60210349_atMOLT44.7074.410Details
BioGPS NCI60210349_atNCI 4604.4884.410Details
BioGPS NCI60210349_atNCI H2264.4614.410Details
BioGPS NCI60210349_atNCI H234.3174.410Details
BioGPS NCI60210349_atNCI H322M4.3044.410Details
BioGPS NCI60210349_atNCVADR RES4.0894.410Details
BioGPS NCI60210349_atOVCAR34.6044.410Details
BioGPS NCI60210349_atOVCAR44.3334.410Details
BioGPS NCI60210349_atOVCAR54.2544.410Details
BioGPS NCI60210349_atOVCAR84.0674.410Details
BioGPS NCI60210349_atPANC14.4444.410Details
BioGPS NCI60210349_atRL74.4564.410Details
BioGPS NCI60210349_atRPMI 82264.4114.410Details
BioGPS NCI60210349_atRS118464.6354.410Details
BioGPS NCI60210349_atRXF3934.3184.410Details
BioGPS NCI60210349_atSAOS24.4144.410Details
BioGPS NCI60210349_atSF2684.3164.410Details
BioGPS NCI60210349_atSF2954.2334.410Details
BioGPS NCI60210349_atSF5394.0964.410Details
BioGPS NCI60210349_atSHSYSY+RA4.2094.410Details
BioGPS NCI60210349_atSHSYSY-RA4.2664.410Details
BioGPS NCI60210349_atSKMEL24.2974.410Details
BioGPS NCI60210349_atSKMEL284.3734.410Details
BioGPS NCI60210349_atSKMEL54.1564.410Details
BioGPS NCI60210349_atSKOV34.5594.410Details
BioGPS NCI60210349_atSN12C4.4164.410Details
BioGPS NCI60210349_atSNB194.0694.410Details
BioGPS NCI60210349_atSNB754.2974.410Details
BioGPS NCI60210349_atSR4.5274.410Details
BioGPS NCI60210349_atSW6204.9334.410Details
BioGPS NCI60210349_atT244.5094.410Details
BioGPS NCI60210349_atT3M44.5814.410Details
BioGPS NCI60210349_atTK104.3154.410Details
BioGPS NCI60210349_atU1184.2134.410Details
BioGPS NCI60210349_atU1384.0634.410Details
BioGPS NCI60210349_atU20S4.2224.410Details
BioGPS NCI60210349_atU2514.2734.410Details
BioGPS NCI60210349_atU874.2044.410Details
BioGPS NCI60210349_atUACC2574.2244.410Details
BioGPS NCI60210349_atUACC624.4584.410Details
BioGPS NCI60210349_atUO314.1924.410Details
BioGPS NCI60210349_atZR75_14.6514.410Details
BioGPS NCI60210349_atastrocytes4.3384.410Details
BioGPS NCI60210349_athuh-74.5464.410Details