Search Antibody, Protein, and ELISA Kit Solutions


Gene ID: 817 | CAMK2D Antibody Resource


CAMK2D Antibody Resource
Gene Full Name: 
calcium/calmodulin-dependent protein kinase II delta
Uniprot: 
Q13557
Protein Name: 
calcium/calmodulin-dependent protein kinase type II subunit delta
Nucleotide: 
NM_172128
Alias: 
CAMKD;
Ensembl: 
ENSG00000145349
Location: 
4q26
HPRD: 
09653
NCBI Gene: 
817
MIM: 
607708

Summary: 
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.[provided by RefSeq, Nov 2008]
Function: 
Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca2+ homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca2+ influx into the myocyte, Ca2+ release from the sarcoplasmic reticulum (SR), SR Ca2+ uptake and Na+ and K+ channel transport. Targets also transcription factors and signaling molecules to regulate heart function. In its activated form, is involved in the pathogenesis of dilated cardiomyopathy and heart failure. Contributes to cardiac decompensation and heart failure by regulating SR Ca2+ release via direct phosphorylation of RYR2 Ca2+ channel on 'Ser-2808'. In the nucleus, phosphorylates the MEF2 repressor HDAC4, promoting its nuclear export and binding to 14-3-3 protein, and expression of MEF2 and genes involved in the hypertrophic program. Is essential for left ventricular remodeling responses to myocardial infarction. In pathological myocardial remodeling acts downstream of the beta adrenergic receptor signaling cascade to regulate key proteins involved in ECC. Regulates Ca2+ influx to myocytes by binding and phosphorylating the L-type Ca2+ channel subunit beta-2 CACNB2. In addition to Ca2+ channels, can target and regulate the cardiac sarcolemmal Na+ channel Nav1.5/SCN5A and the K+ channel Kv4.3/KCND3, which contribute to arrhythmogenesis in heart failure. Phosphorylates phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2, contributing to the enhancement of SR Ca2+ uptake that may be important in frequency-dependent acceleration of relaxation (FDAR) and maintenance of contractile function during acidosis. May participate in the modulation of skeletal muscle function in response to exercise, by regulating SR Ca2+ transport through phosphorylation of PLN/PLB and triadin, a ryanodine receptor-coupling factor.
Subcellular location: 
Cell membrane › sarcolemma; Peripheral membrane protein; Cytoplasmic side Probable. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side Probable.
PTM: 
Acetylation;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP61459_P050 CAMK2D antibody - C-terminal region (ARP61459_P050) Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rat, Zebrafish WB 50ug $289 Details
Polyclonal Antibody OAAB10098 Mouse Camk2d antibody - center region (OAAB10098) Human; Mouse WB, IHC 400ul $289 Details
Polyclonal Antibody OAAB16986 CAMK2D (CAMK2 delta) antibody - C - terminal region (OAAB16986) Human; Monkey WB, IHC 400ul $289 Details
Polyclonal Antibody OAGA00902 CAMK2D antibody (OAGA00902) Polyclonal Human, Mouse, Rabbit ICC/IF, WB 100 ul $340 Details
Polyclonal Antibody OAAF03399 CAMK2D Antibody (OAAF03399) Polyclonal Human, Mouse, Rat WB, ELISA 100 ug $229 Details
Polyclonal Antibody OAAF00291 CAMK2D (Phospho-Thr286) Antibody (OAAF00291) Polyclonal Human, Mouse, Rat WB, IHC, IF, ELISA 100 ug $229 Details
Polyclonal Antibody OAAF01253 CAMK2D Antibody (OAAF01253) Polyclonal Human, Mouse, Rat WB, IHC, IF, ELISA 100 ug $229 Details

Show all CAMK2D antibodies


Product Images
CAMK2D antibody - C-terminal region (ARP61459_P050) in Human HT1080 cells using Western Blot

Sample Type: Human HT1080

Mouse Camk2d antibody - center region (OAAB10098) in 293 cells using Western Blot

Sample Type: 293

Mouse Camk2d antibody - center region (OAAB10098) in 293 cells using Western Blot

Sample Type: 293

Mouse Camk2d antibody - center region (OAAB10098) in Mouse Heart cells using Immunohistochemistry

Sample Type: Mouse Heart

CAMK2D (CAMK2 delta) antibody - C - terminal region (OAAB16986) in Hela cells using Western Blot

Sample Type: Hela

CAMK2D (CAMK2 delta) antibody - C - terminal region (OAAB16986) in Human Brain cells using Immunohistochemistry

Sample Type: Human Brain

CAMK2D (CAMK2 delta) antibody - C - terminal region (OAAB16986) in Human cancer, breast carcinoma, hepatocarcinoma cells using Immunohistochemistry

Sample Type: Human cancer, breast carcinoma, hepatocarcinoma

CAMK2D (Phospho-Thr286) Antibody (OAAF00291) in COS-7 cells using Immunofluorescence

Sample Type: COS-7

CAMK2D (Phospho-Thr286) Antibody (OAAF00291) in Human brain cells using Immunohistochemistry

Sample Type: Human brain

CAMK2D (Phospho-Thr286) Antibody (OAAF00291) in K562 cells using Western Blot

Sample Type: K562

CAMK2D Antibody (OAAF01253) in Human brain cells using Immunohistochemistry

Sample Type: Human brain

CAMK2D Antibody (OAAF01253) in MCF7 cells using Immunofluorescence

Sample Type: MCF7

CAMK2D Antibody (OAAF01253) in NIH-3T3, K562 cells using Western Blot

Sample Type: NIH-3T3, K562

CAMK2D Antibody (OAAF03399) in JK, COLO, HuvEc, A549 cells using Western Blot

Sample Type: JK, COLO, HuvEc, A549


CAMK2D Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP61370 African clawed frog CAMK2D antibody; Xenopus laevis CAMK2D antibody Q9DG02 100.0%
ARP61459 African clawed frog CAMK2D antibody; Xenopus laevis CAMK2D antibody Q9DG02 100.0%
ARP61370 African clawed frog CAMK2D antibody; Xenopus laevis CAMK2D antibody B7ZPP0 100.0%
ARP61459 African clawed frog CAMK2D antibody; Xenopus laevis CAMK2D antibody B7ZPP0 100.0%
ARP61370 Bovine CAMK2D antibody; Bos taurus CAMK2D antibody Q2HJF7 100.0%
ARP61370 Bovine CAMK2D antibody; Bos taurus CAMK2D antibody A5D9F0 100.0%
ARP61459 Bovine CAMK2D antibody; Bos taurus CAMK2D antibody A5D9F0 100.0%
ARP61370 Cat CAMK2D antibody; Felis catus CAMK2D antibody M3WNF0 100.0%
ARP61459 Cat CAMK2D antibody; Felis catus CAMK2D antibody M3WNF0 100.0%
ARP61370 Chicken CAMK2D antibody; Gallus gallus CAMK2D antibody F1NG22 100.0%
ARP61370 Chicken CAMK2D antibody; Gallus gallus CAMK2D antibody Q5ZKI0 100.0%
ARP61459 Chicken CAMK2D antibody; Gallus gallus CAMK2D antibody Q5ZKI0 100.0%
ARP61370 Chicken CAMK2D antibody; Gallus gallus CAMK2D antibody E1C3I7 100.0%
ARP61459 Chicken CAMK2D antibody; Gallus gallus CAMK2D antibody E1C3I7 100.0%
ARP61459 Chicken CAMK2D antibody; Gallus gallus CAMK2D antibody F1NG22 92.0%
ARP61370 Chimpanzee CAMK2D antibody; Pan troglodytes CAMK2D antibody K7BKT6 100.0%
ARP61459 Chimpanzee CAMK2D antibody; Pan troglodytes CAMK2D antibody K7BKT6 100.0%
ARP61370 Chimpanzee CAMK2D antibody; Pan troglodytes CAMK2D antibody H2QQ24 100.0%
ARP61459 Chimpanzee CAMK2D antibody; Pan troglodytes CAMK2D antibody H2QQ24 100.0%
ARP61370 Chinese softshell turtle CAMK2D antibody; Pelodiscus sinensis CAMK2D antibody K7G522 100.0%
ARP61459 Chinese softshell turtle CAMK2D antibody; Pelodiscus sinensis CAMK2D antibody K7G522 100.0%
ARP61459 Chinese softshell turtle CAMK2D antibody; Pelodiscus sinensis CAMK2D antibody K7G550 92.0%
ARP61459 Collared flycatcher CAMK2D antibody; Ficedula albicollis CAMK2D antibody U3JE81 92.0%
ARP61370 Dog CAMK2D antibody; Canis familiaris CAMK2D antibody E2RR97 100.0%
ARP61459 Dog CAMK2D antibody; Canis familiaris CAMK2D antibody E2RR74 92.0%
ARP61459 Dog CAMK2D antibody; Canis familiaris CAMK2D antibody E2RR97 92.0%
ARP61459 Domestic duck CAMK2D antibody; Anas platyrhynchos CAMK2D antibody U3IR08 100.0%
ARP61370 Duckbill platypus CAMK2D antibody; Ornithorhynchus anatinus CAMK2D antibody F7EII5 100.0%
ARP61459 Duckbill platypus CAMK2D antibody; Ornithorhynchus anatinus CAMK2D antibody F7EII5 92.0%
ARP61459 European domestic ferret CAMK2D antibody; Mustela putorius furo CAMK2D antibody M3YA76 92.0%
ARP61370 Giant panda CAMK2D antibody; Ailuropoda melanoleuca CAMK2D antibody G1LRM2 100.0%
ARP61459 Giant panda CAMK2D antibody; Ailuropoda melanoleuca CAMK2D antibody G1LRM2 100.0%
ARP61459 Giant panda CAMK2D antibody; Ailuropoda melanoleuca CAMK2D antibody G1LRN5 92.0%
ARP61370 Gray short-tailed opossum CAMK2D antibody; Monodelphis domestica CAMK2D antibody F7D2P3 100.0%
ARP61459 Gray short-tailed opossum CAMK2D antibody; Monodelphis domestica CAMK2D antibody F7D2P3 93.0%
ARP61459 Green anole CAMK2D antibody; Anolis carolinensis CAMK2D antibody L7MZX9 92.0%
ARP61370 Guinea pig CAMK2D antibody; Cavia porcellus CAMK2D antibody H0V2G6 100.0%
ARP61459 Guinea pig CAMK2D antibody; Cavia porcellus CAMK2D antibody H0V2G6 100.0%
ARP61370 Horse CAMK2D antibody; Equus caballus CAMK2D antibody F6PTM3 100.0%
ARP61459 Horse CAMK2D antibody; Equus caballus CAMK2D antibody F6PTM3 100.0%
ARP61370 Horse CAMK2D antibody; Equus caballus CAMK2D antibody F6XS23 100.0%
ARP61370 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q13557-3 100.0%
ARP61370 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q13557-5 100.0%
ARP61370 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q13557-6 100.0%
ARP61370 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q13557-8 100.0%
ARP61459 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q13557-8 100.0%
ARP61370 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q13557-9 100.0%
ARP61370 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q13557 100.0%
ARP61459 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q13557 100.0%
ARP61370 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q4G1A8 100.0%
ARP61370 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q13557-10 100.0%
ARP61370 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q13557-12 100.0%
ARP61459 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q13557-12 100.0%
ARP61459 Human CAMK2D antibody; Homo sapiens CAMK2D antibody H0Y9J2 100.0%
ARP61370 Human CAMK2D antibody; Homo sapiens CAMK2D antibody D6R938 100.0%
ARP61459 Human CAMK2D antibody; Homo sapiens CAMK2D antibody D6R938 100.0%
ARP61370 Human CAMK2D antibody; Homo sapiens CAMK2D antibody E9PBG7 100.0%
ARP61459 Human CAMK2D antibody; Homo sapiens CAMK2D antibody H0Y9C2 93.0%
ARP61459 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q13557-6 92.0%
ARP61459 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q13557-10 92.0%
ARP61459 Human CAMK2D antibody; Homo sapiens CAMK2D antibody Q13557-11 92.0%
ARP61459 Human CAMK2D antibody; Homo sapiens CAMK2D antibody E9PBG7 92.0%
ARP61459 Human CAMK2D antibody; Homo sapiens CAMK2D antibody E9PF82 92.0%
ARP61370 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody E9Q1V9 100.0%
ARP61370 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody E9Q1W0 100.0%
ARP61370 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody E9QAJ4 100.0%
ARP61370 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody Q6PHZ2-2 100.0%
ARP61459 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody Q6PHZ2-2 100.0%
ARP61370 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody Q6PHZ2-4 100.0%
ARP61370 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody Q6PHZ2-5 100.0%
ARP61370 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody Q6PHZ2 100.0%
ARP61459 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody Q6PHZ2 100.0%
ARP61459 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody Q8C8X9 100.0%
ARP61370 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody Q8CCM0 100.0%
ARP61459 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody Q8CCM0 100.0%
ARP61370 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody D6RDQ8 100.0%
ARP61370 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody E9PXV3 100.0%
ARP61370 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody E9PYZ8 100.0%
ARP61459 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody E9Q1V9 92.0%
ARP61459 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody Q6PHZ2-4 92.0%
ARP61459 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody F6ZIE1 92.0%
ARP61459 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody Q6PHZ2-5 92.0%
ARP61459 Mouse CAMK2D antibody; Mus musculus CAMK2D antibody E9Q1T1 92.0%
ARP61370 Northern white-cheeked gibbon CAMK2D antibody; Nomascus leucogenys CAMK2D antibody G1S2H9 100.0%
ARP61459 Northern white-cheeked gibbon CAMK2D antibody; Nomascus leucogenys CAMK2D antibody G1S2H9 100.0%
ARP61370 Pig CAMK2D antibody; Sus scrofa CAMK2D antibody Q95266 100.0%
ARP61459 Pig CAMK2D antibody; Sus scrofa CAMK2D antibody Q95266 100.0%
ARP61370 Rabbit CAMK2D antibody; Oryctolagus cuniculus CAMK2D antibody O77708-2 100.0%
ARP61459 Rabbit CAMK2D antibody; Oryctolagus cuniculus CAMK2D antibody O77708-2 100.0%
ARP61370 Rabbit CAMK2D antibody; Oryctolagus cuniculus CAMK2D antibody O77708-3 100.0%
ARP61370 Rabbit CAMK2D antibody; Oryctolagus cuniculus CAMK2D antibody O77708-4 100.0%
ARP61459 Rabbit CAMK2D antibody; Oryctolagus cuniculus CAMK2D antibody O77708-4 100.0%
ARP61370 Rabbit CAMK2D antibody; Oryctolagus cuniculus CAMK2D antibody O77708-6 100.0%
ARP61459 Rabbit CAMK2D antibody; Oryctolagus cuniculus CAMK2D antibody O77708-5 92.0%
ARP61459 Rabbit CAMK2D antibody; Oryctolagus cuniculus CAMK2D antibody O77708-6 92.0%
ARP61459 Rabbit CAMK2D antibody; Oryctolagus cuniculus CAMK2D antibody O77708 92.0%
ARP61459 Rabbit CAMK2D antibody; Oryctolagus cuniculus CAMK2D antibody G1TVE5 92.0%
ARP61370 Rat CAMK2D antibody; Rattus norvegicus CAMK2D antibody F1LWF6 100.0%
ARP61370 Rat CAMK2D antibody; Rattus norvegicus CAMK2D antibody P15791-2 100.0%
ARP61459 Rat CAMK2D antibody; Rattus norvegicus CAMK2D antibody P15791-2 100.0%
ARP61370 Rat CAMK2D antibody; Rattus norvegicus CAMK2D antibody P15791-3 100.0%
ARP61370 Rat CAMK2D antibody; Rattus norvegicus CAMK2D antibody P15791-5 100.0%
ARP61459 Rat CAMK2D antibody; Rattus norvegicus CAMK2D antibody P15791-5 100.0%
ARP61370 Rat CAMK2D antibody; Rattus norvegicus CAMK2D antibody P15791-6 100.0%
ARP61370 Rat CAMK2D antibody; Rattus norvegicus CAMK2D antibody P15791-7 100.0%
ARP61459 Rat CAMK2D antibody; Rattus norvegicus CAMK2D antibody P15791-6 92.0%
ARP61459 Rat CAMK2D antibody; Rattus norvegicus CAMK2D antibody P15791 92.0%
ARP61459 Rhesus macaque CAMK2D antibody; Macaca mulatta CAMK2D antibody I0FVE7 100.0%
ARP61370 Rhesus macaque CAMK2D antibody; Macaca mulatta CAMK2D antibody F6UGY3 100.0%
ARP61459 Rhesus macaque CAMK2D antibody; Macaca mulatta CAMK2D antibody F6UGY3 100.0%
ARP61370 Rhesus macaque CAMK2D antibody; Macaca mulatta CAMK2D antibody F6UHD3 100.0%
ARP61459 Rhesus macaque CAMK2D antibody; Macaca mulatta CAMK2D antibody F6UHD3 100.0%
ARP61370 Rhesus macaque CAMK2D antibody; Macaca mulatta CAMK2D antibody F7H4F4 100.0%
ARP61370 Rhesus macaque CAMK2D antibody; Macaca mulatta CAMK2D antibody F7H4G9 100.0%
ARP61459 Rhesus macaque CAMK2D antibody; Macaca mulatta CAMK2D antibody F7H4G9 100.0%
ARP61370 Rhesus macaque CAMK2D antibody; Macaca mulatta CAMK2D antibody F7H4H1 100.0%
ARP61370 Rhesus macaque CAMK2D antibody; Macaca mulatta CAMK2D antibody F7H4H3 100.0%
ARP61370 Rhesus macaque CAMK2D antibody; Macaca mulatta CAMK2D antibody I0FVE6 100.0%
ARP61459 Rhesus macaque CAMK2D antibody; Macaca mulatta CAMK2D antibody I0FVE6 100.0%
ARP61370 Rhesus macaque CAMK2D antibody; Macaca mulatta CAMK2D antibody I0FVE7 100.0%
ARP61459 Rhesus macaque CAMK2D antibody; Macaca mulatta CAMK2D antibody F7H4F4 92.0%
ARP61370 Small-eared galago CAMK2D antibody; Otolemur garnettii CAMK2D antibody H0X285 100.0%
ARP61459 Small-eared galago CAMK2D antibody; Otolemur garnettii CAMK2D antibody H0X285 92.0%
ARP61459 Sumatran orangutan CAMK2D antibody; Pongo abelii CAMK2D antibody H2PE58 92.0%
ARP61459 Tasmanian devil CAMK2D antibody; Sarcophilus harrisii CAMK2D antibody G3W0V1 93.0%
ARP61459 Thirteen-lined ground squirrel CAMK2D antibody; Spermophilus tridecemlineatus CAMK2D antibody I3LZ28 100.0%
ARP61370 Western clawed frog CAMK2D antibody; Xenopus tropicalis CAMK2D antibody F6UQZ6 100.0%
ARP61370 Western clawed frog CAMK2D antibody; Xenopus tropicalis CAMK2D antibody A9ULG8 100.0%
ARP61459 Western clawed frog CAMK2D antibody; Xenopus tropicalis CAMK2D antibody A9ULG8 100.0%
ARP61459 Western clawed frog CAMK2D antibody; Xenopus tropicalis CAMK2D antibody F6UQZ6 92.0%
ARP61370 White-tufted-ear marmoset CAMK2D antibody; Callithrix jacchus CAMK2D antibody F7H163 100.0%
ARP61370 White-tufted-ear marmoset CAMK2D antibody; Callithrix jacchus CAMK2D antibody U3D4V3 100.0%
ARP61370 White-tufted-ear marmoset CAMK2D antibody; Callithrix jacchus CAMK2D antibody U3EKS9 100.0%
ARP61459 White-tufted-ear marmoset CAMK2D antibody; Callithrix jacchus CAMK2D antibody U3EKS9 100.0%
ARP61459 White-tufted-ear marmoset CAMK2D antibody; Callithrix jacchus CAMK2D antibody U3D4V3 92.0%
ARP61459 Zebra finch CAMK2D antibody; Taeniopygia guttata CAMK2D antibody H0YUC5 92.0%

Tissue & Cell Line Gene Expression Data