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Gene ID: 125972 | CALR3 Antibody Resource


CALR3 Antibody Resource
Gene Full Name: 
calreticulin 3
Uniprot: 
Q96L12
Protein Name: 
calreticulin-3
Nucleotide: 
XM_005259729
Alias: 
CRT2;CT93;CMH19;
Ensembl: 
ENSG00000269058
Location: 
19p13.11
HPRD: 
12999
NCBI Gene: 
125972
MIM: 
611414

Summary: 
The protein encoded by this gene belongs to the calreticulin family, members of which are calcium-binding chaperones localized mainly in the endoplasmic reticulum. This protein is also localized to the endoplasmic reticulum lumen, however, its capacity for calcium-binding may be absent or much lower than other family members. This gene is specifically expressed in the testis, and may be required for sperm fertility. Mutation in this gene has been associated with familial hypertrophic cardiomyopathy. [provided by RefSeq, Dec 2011]
Function: 
During spermatogenesis, may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Required for sperm fertility . CALR3 capacity for calcium-binding may be absent or much lower than that of CALR.
Subcellular location: 
Endoplasmic reticulum lumen .
PTM: 
Disulfide bond;
Disease: 
Cardiomyopathy, familial hypertrophic 19 (CMH19) [MIM:613875]: A hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP58601_P050 CALR3 antibody - N-terminal region (ARP58601_P050) Polyclonal Bovine, Dog, Guinea pig, Human, Mouse, Rat WB 50ug $289 Details

Show all CALR3 antibodies


Product Images
CALR3 antibody - N-terminal region (ARP58601_P050) in Human Jurkat cells using Western Blot

Sample Type: Human Jurkat


CALR3 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP58601 Bovine CALR3 antibody; Bos taurus CALR3 antibody F1MTN0 93.0%
ARP58601 Bovine CALR3 antibody; Bos taurus CALR3 antibody Q2TBR8 93.0%
ARP58123 Bovine CALR3 antibody; Bos taurus CALR3 antibody F1MTN0 85.0%
ARP58123 Bovine CALR3 antibody; Bos taurus CALR3 antibody Q2TBR8 85.0%
ARP58879 Bovine CALR3 antibody; Bos taurus CALR3 antibody F1MTN0 82.0%
ARP58879 Bovine CALR3 antibody; Bos taurus CALR3 antibody Q2TBR8 82.0%
ARP58601 Cat CALR3 antibody; Felis catus CALR3 antibody M3X9Z5 100.0%
ARP58123 Cat CALR3 antibody; Felis catus CALR3 antibody M3X9Z5 86.0%
ARP58879 Cat CALR3 antibody; Felis catus CALR3 antibody M3X9Z5 82.0%
ARP58601 Chimpanzee CALR3 antibody; Pan troglodytes CALR3 antibody H2QFP5 100.0%
ARP58601 Dog CALR3 antibody; Canis familiaris CALR3 antibody E2RGY6 100.0%
ARP58123 Dog CALR3 antibody; Canis familiaris CALR3 antibody E2RGY6 86.0%
ARP58879 Dog CALR3 antibody; Canis familiaris CALR3 antibody E2RGY6 82.0%
ARP58601 European domestic ferret CALR3 antibody; Mustela putorius furo CALR3 antibody M3YX68 100.0%
ARP58123 European domestic ferret CALR3 antibody; Mustela putorius furo CALR3 antibody M3YX68 86.0%
ARP58879 European domestic ferret CALR3 antibody; Mustela putorius furo CALR3 antibody M3YX68 82.0%
ARP58601 Giant panda CALR3 antibody; Ailuropoda melanoleuca CALR3 antibody G1LTZ3 100.0%
ARP58123 Giant panda CALR3 antibody; Ailuropoda melanoleuca CALR3 antibody G1LTZ3 86.0%
ARP58879 Giant panda CALR3 antibody; Ailuropoda melanoleuca CALR3 antibody G1LTZ3 82.0%
ARP58123 Gray short-tailed opossum CALR3 antibody; Monodelphis domestica CALR3 antibody F7FVR7 86.0%
ARP36626 Gray short-tailed opossum CALR3 antibody; Monodelphis domestica CALR3 antibody F7FVR7 85.0%
ARP58601 Horse CALR3 antibody; Equus caballus CALR3 antibody F7A7K1 100.0%
ARP58123 Horse CALR3 antibody; Equus caballus CALR3 antibody F7A7K1 86.0%
ARP58879 Horse CALR3 antibody; Equus caballus CALR3 antibody F7A7K1 82.0%
ARP58601 Human CALR3 antibody; Homo sapiens CALR3 antibody Q96L12 100.0%
ARP58123 Human CALR3 antibody; Homo sapiens CALR3 antibody Q96L12 86.0%
ARP58879 Human CALR3 antibody; Homo sapiens CALR3 antibody Q96L12 82.0%
ARP58601 Mouse CALR3 antibody; Mus musculus CALR3 antibody B1Q2L7 92.0%
ARP58601 Mouse CALR3 antibody; Mus musculus CALR3 antibody Q9D9Q6 92.0%
ARP58123 Mouse CALR3 antibody; Mus musculus CALR3 antibody B1Q2L7 86.0%
ARP58123 Mouse CALR3 antibody; Mus musculus CALR3 antibody Q9D9Q6 86.0%
ARP58879 Mouse CALR3 antibody; Mus musculus CALR3 antibody Q9D9Q6 82.0%
ARP58879 Mouse CALR3 antibody; Mus musculus CALR3 antibody B1Q2L7 82.0%
ARP58601 Northern white-cheeked gibbon CALR3 antibody; Nomascus leucogenys CALR3 antibody G1R0F1 100.0%
ARP58123 Northern white-cheeked gibbon CALR3 antibody; Nomascus leucogenys CALR3 antibody G1R0F1 86.0%
ARP58879 Northern white-cheeked gibbon CALR3 antibody; Nomascus leucogenys CALR3 antibody G1R0F1 82.0%
ARP58601 Pig CALR3 antibody; Sus scrofa CALR3 antibody F1S9W5 93.0%
ARP58123 Pig CALR3 antibody; Sus scrofa CALR3 antibody F1S9W5 86.0%
ARP58879 Pig CALR3 antibody; Sus scrofa CALR3 antibody F1S9W5 82.0%
ARP58601 Rabbit CALR3 antibody; Oryctolagus cuniculus CALR3 antibody G1T5M9 93.0%
ARP58123 Rabbit CALR3 antibody; Oryctolagus cuniculus CALR3 antibody G1T5M9 86.0%
ARP58879 Rabbit CALR3 antibody; Oryctolagus cuniculus CALR3 antibody G1T5M9 82.0%
ARP58601 Rat CALR3 antibody; Rattus norvegicus CALR3 antibody Q6AYG8 92.0%
ARP58123 Rat CALR3 antibody; Rattus norvegicus CALR3 antibody Q6AYG8 86.0%
ARP58879 Rat CALR3 antibody; Rattus norvegicus CALR3 antibody Q6AYG8 82.0%
ARP58601 Small-eared galago CALR3 antibody; Otolemur garnettii CALR3 antibody H0WSX7 100.0%
ARP58123 Small-eared galago CALR3 antibody; Otolemur garnettii CALR3 antibody H0WSX7 86.0%
ARP58879 Small-eared galago CALR3 antibody; Otolemur garnettii CALR3 antibody H0WSX7 82.0%
ARP58601 Sumatran orangutan CALR3 antibody; Pongo abelii CALR3 antibody H2NXY3 100.0%
ARP36626 Tasmanian devil CALR3 antibody; Sarcophilus harrisii CALR3 antibody G3WA24 86.0%
ARP58123 Tasmanian devil CALR3 antibody; Sarcophilus harrisii CALR3 antibody G3WA24 86.0%
ARP58601 Thirteen-lined ground squirrel CALR3 antibody; Spermophilus tridecemlineatus CALR3 antibody I3MII4 100.0%
ARP58123 Thirteen-lined ground squirrel CALR3 antibody; Spermophilus tridecemlineatus CALR3 antibody I3MII4 86.0%
ARP58879 Thirteen-lined ground squirrel CALR3 antibody; Spermophilus tridecemlineatus CALR3 antibody I3MII4 82.0%
ARP58879 Western clawed frog CALR3 antibody; Xenopus tropicalis CALR3 antibody F7E4B5 93.0%
ARP58601 White-tufted-ear marmoset CALR3 antibody; Callithrix jacchus CALR3 antibody U3CRS1 100.0%
ARP58123 White-tufted-ear marmoset CALR3 antibody; Callithrix jacchus CALR3 antibody U3CRS1 85.0%
ARP58879 White-tufted-ear marmoset CALR3 antibody; Callithrix jacchus CALR3 antibody U3CRS1 82.0%

Tissue & Cell Line Gene Expression Data