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Gene ID: 91768 | CABLES1 Antibody Resource


CABLES1 Antibody Resource
Gene Full Name: 
Cdk5 and Abl enzyme substrate 1
Uniprot: 
Q8TDN4
Protein Name: 
CDK5 and ABL1 enzyme substrate 1
Nucleotide: 
NM_001256438
Alias: 
CABL1;IK3-1;CABLES;HsT2563;
Ensembl: 
ENSG00000134508
Location: 
18q11.2
HPRD: 
16461
NCBI Gene: 
91768
MIM: 
609194

Summary: 
This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Function: 
Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death .
Subcellular location: 
Nucleus. Cytoplasm. Note: Located in the cell body and proximal region of the developing axonal shaft of immature neurons. Located in axonal growth cone, but not in the distal part of the axon shaft or in dendritic growth cone of mature neurons .
PTM: 
Phosphoprotein;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB06428 CABLES1 antibody - C-terminal region (OAAB06428) Human; Mouse WB, IHC 400ul $289 Details
Polyclonal Antibody ARP64759_P050 CABLES1 antibody - C-terminal region (ARP64759_P050) Human WB 50ug $289 Details
Polyclonal Antibody ARP64758_P050 CABLES1 Antibody - C-terminal region (ARP64758_P050) Human WB 50ug $289 Details
Polyclonal Antibody OAAF02840 CABLES1 Antibody (OAAF02840) Polyclonal Human, Mouse WB, ELISA 100 ug $229 Details

Show all CABLES1 antibodies


Product Images
CABLES1 Antibody - C-terminal region (ARP64758_P050) in Human Fetal heart cells using Western Blot

Sample Type: Human Fetal heart

CABLES1 antibody - C-terminal region (ARP64759_P050) in Human RPMI-8226 cells using Western Blot

Sample Type: Human RPMI-8226

CABLES1 Antibody (OAAF02840) in LOVO cells using Western Blot

Sample Type: LOVO


CABLES1 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP64759 Cat CABLES1 antibody; Felis catus CABLES1 antibody M3VUX3 100.0%
ARP64758 Cat CABLES1 antibody; Felis catus CABLES1 antibody M3VUX3 93.0%
ARP64759 Chicken CABLES1 antibody; Gallus gallus CABLES1 antibody F1NSZ8 100.0%
ARP64758 Chicken CABLES1 antibody; Gallus gallus CABLES1 antibody F1NSZ8 86.0%
ARP64758 Chimpanzee CABLES1 antibody; Pan troglodytes CABLES1 antibody H2QEC2 100.0%
ARP64759 Chimpanzee CABLES1 antibody; Pan troglodytes CABLES1 antibody H2QEC2 100.0%
ARP64759 Chinese softshell turtle CABLES1 antibody; Pelodiscus sinensis CABLES1 antibody K7FFB7 100.0%
ARP64758 Chinese softshell turtle CABLES1 antibody; Pelodiscus sinensis CABLES1 antibody K7FFB7 86.0%
ARP64759 Collared flycatcher CABLES1 antibody; Ficedula albicollis CABLES1 antibody U3JUG0 100.0%
ARP64758 Collared flycatcher CABLES1 antibody; Ficedula albicollis CABLES1 antibody U3JUG0 86.0%
ARP64759 Dog CABLES1 antibody; Canis familiaris CABLES1 antibody F1P9I2 100.0%
ARP64759 Dog CABLES1 antibody; Canis familiaris CABLES1 antibody J9NS04 100.0%
ARP64758 Dog CABLES1 antibody; Canis familiaris CABLES1 antibody F1P9I2 93.0%
ARP64758 Dog CABLES1 antibody; Canis familiaris CABLES1 antibody J9NS04 93.0%
ARP64759 Domestic duck CABLES1 antibody; Anas platyrhynchos CABLES1 antibody U3IFB6 100.0%
ARP64758 Domestic duck CABLES1 antibody; Anas platyrhynchos CABLES1 antibody U3IFB6 86.0%
ARP64759 Duckbill platypus CABLES1 antibody; Ornithorhynchus anatinus CABLES1 antibody F7G1R3 100.0%
ARP64759 European domestic ferret CABLES1 antibody; Mustela putorius furo CABLES1 antibody M3Y2T4 100.0%
ARP64758 European domestic ferret CABLES1 antibody; Mustela putorius furo CABLES1 antibody M3Y2T4 93.0%
ARP64759 Giant panda CABLES1 antibody; Ailuropoda melanoleuca CABLES1 antibody G1M556 100.0%
ARP64758 Giant panda CABLES1 antibody; Ailuropoda melanoleuca CABLES1 antibody G1M556 93.0%
ARP64759 Gray short-tailed opossum CABLES1 antibody; Monodelphis domestica CABLES1 antibody F7G2S6 100.0%
ARP64758 Gray short-tailed opossum CABLES1 antibody; Monodelphis domestica CABLES1 antibody F7G2S6 79.0%
ARP64759 Green anole CABLES1 antibody; Anolis carolinensis CABLES1 antibody G1K8C3 100.0%
ARP64758 Green anole CABLES1 antibody; Anolis carolinensis CABLES1 antibody G1K8C3 86.0%
ARP64759 Horse CABLES1 antibody; Equus caballus CABLES1 antibody F6TB29 100.0%
ARP64758 Horse CABLES1 antibody; Equus caballus CABLES1 antibody F6TB29 93.0%
ARP64758 Human CABLES1 antibody; Homo sapiens CABLES1 antibody Q8TDN4 100.0%
ARP64759 Human CABLES1 antibody; Homo sapiens CABLES1 antibody Q8TDN4 100.0%
ARP64758 Human CABLES1 antibody; Homo sapiens CABLES1 antibody Q8TDN4-2 100.0%
ARP64759 Human CABLES1 antibody; Homo sapiens CABLES1 antibody Q8TDN4-2 100.0%
ARP64758 Human CABLES1 antibody; Homo sapiens CABLES1 antibody Q8TDN4-3 100.0%
ARP64758 Human CABLES1 antibody; Homo sapiens CABLES1 antibody Q8TDN4-4 100.0%
ARP64759 Human CABLES1 antibody; Homo sapiens CABLES1 antibody Q8TDN4-4 100.0%
ARP64759 Mouse CABLES1 antibody; Mus musculus CABLES1 antibody B2RWU9 100.0%
ARP64759 Mouse CABLES1 antibody; Mus musculus CABLES1 antibody Q9ESJ1 100.0%
ARP64759 Mouse CABLES1 antibody; Mus musculus CABLES1 antibody Q3TYS6 100.0%
ARP64759 Mouse CABLES1 antibody; Mus musculus CABLES1 antibody Q3U148 100.0%
ARP64758 Mouse CABLES1 antibody; Mus musculus CABLES1 antibody B2RWU9 93.0%
ARP64758 Mouse CABLES1 antibody; Mus musculus CABLES1 antibody Q9ESJ1 93.0%
ARP64758 Mouse CABLES1 antibody; Mus musculus CABLES1 antibody Q3TYS6 93.0%
ARP64758 Mouse CABLES1 antibody; Mus musculus CABLES1 antibody Q3U148 93.0%
ARP64759 Nile tilapia CABLES1 antibody; Oreochromis niloticus CABLES1 antibody I3JSH0 100.0%
ARP64759 Nile tilapia CABLES1 antibody; Oreochromis niloticus CABLES1 antibody I3JSH1 100.0%
ARP64758 Northern white-cheeked gibbon CABLES1 antibody; Nomascus leucogenys CABLES1 antibody G1R4Y7 100.0%
ARP64759 Northern white-cheeked gibbon CABLES1 antibody; Nomascus leucogenys CABLES1 antibody G1R4Y7 100.0%
ARP64759 Pig CABLES1 antibody; Sus scrofa CABLES1 antibody F1SBB7 100.0%
ARP64758 Pig CABLES1 antibody; Sus scrofa CABLES1 antibody F1SBB7 93.0%
ARP64759 Rabbit CABLES1 antibody; Oryctolagus cuniculus CABLES1 antibody G1U9H7 100.0%
ARP64758 Rabbit CABLES1 antibody; Oryctolagus cuniculus CABLES1 antibody G1U9H7 93.0%
ARP64759 Rat CABLES1 antibody; Rattus norvegicus CABLES1 antibody F1LUR9 100.0%
ARP64758 Rat CABLES1 antibody; Rattus norvegicus CABLES1 antibody F1LUR9 93.0%
ARP64758 Rhesus macaque CABLES1 antibody; Macaca mulatta CABLES1 antibody F7BXN6 100.0%
ARP64758 Rhesus macaque CABLES1 antibody; Macaca mulatta CABLES1 antibody H9F686 100.0%
ARP64759 Rhesus macaque CABLES1 antibody; Macaca mulatta CABLES1 antibody H9F686 100.0%
ARP64758 Small-eared galago CABLES1 antibody; Otolemur garnettii CABLES1 antibody H0WXB4 100.0%
ARP64759 Small-eared galago CABLES1 antibody; Otolemur garnettii CABLES1 antibody H0WXB4 100.0%
ARP64758 Sumatran orangutan CABLES1 antibody; Pongo abelii CABLES1 antibody H2NW13 100.0%
ARP64759 Sumatran orangutan CABLES1 antibody; Pongo abelii CABLES1 antibody H2NW13 100.0%
ARP64759 Tasmanian devil CABLES1 antibody; Sarcophilus harrisii CABLES1 antibody G3WJH1 100.0%
ARP64758 Tasmanian devil CABLES1 antibody; Sarcophilus harrisii CABLES1 antibody G3WJH1 86.0%
ARP64759 Thirteen-lined ground squirrel CABLES1 antibody; Spermophilus tridecemlineatus CABLES1 antibody I3MFF3 100.0%
ARP64758 Thirteen-lined ground squirrel CABLES1 antibody; Spermophilus tridecemlineatus CABLES1 antibody I3MFF3 93.0%
ARP64759 Western clawed frog CABLES1 antibody; Xenopus tropicalis CABLES1 antibody F7CFQ7 100.0%
ARP64758 White-tufted-ear marmoset CABLES1 antibody; Callithrix jacchus CABLES1 antibody F7I052 100.0%
ARP64759 White-tufted-ear marmoset CABLES1 antibody; Callithrix jacchus CABLES1 antibody F7I052 100.0%
ARP64758 White-tufted-ear marmoset CABLES1 antibody; Callithrix jacchus CABLES1 antibody F7I2D5 100.0%
ARP64759 White-tufted-ear marmoset CABLES1 antibody; Callithrix jacchus CABLES1 antibody F7I2D5 100.0%
ARP64758 White-tufted-ear marmoset CABLES1 antibody; Callithrix jacchus CABLES1 antibody F7I2G4 100.0%
ARP64758 White-tufted-ear marmoset CABLES1 antibody; Callithrix jacchus CABLES1 antibody F7I2G5 100.0%
ARP64759 White-tufted-ear marmoset CABLES1 antibody; Callithrix jacchus CABLES1 antibody F7I2G5 100.0%
ARP64759 White-tufted-ear marmoset CABLES1 antibody; Callithrix jacchus CABLES1 antibody F7I2G6 100.0%
ARP64759 Zebra finch CABLES1 antibody; Taeniopygia guttata CABLES1 antibody H0ZJE1 100.0%
ARP64758 Zebra finch CABLES1 antibody; Taeniopygia guttata CABLES1 antibody H0ZJE1 86.0%
ARP64759 Zebrafish CABLES1 antibody; Danio rerio CABLES1 antibody A7YX81 100.0%
ARP64759 Zebrafish CABLES1 antibody; Danio rerio CABLES1 antibody H9GXL7 100.0%

Tissue & Cell Line Gene Expression Data