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Gene ID: 203228 | C9orf72 Antibody Resource


C9orf72 Antibody Resource
Gene Full Name: 
chromosome 9 open reading frame 72
Uniprot: 
Q96LT7
Protein Name: 
protein C9orf72
Nucleotide: 
NM_001256054
Alias: 
ALSFTD;FTDALS;
Ensembl: 
ENSG00000147894
Location: 
9p21.2
HPRD: 
12975
NCBI Gene: 
203228
MIM: 
614260

Summary: 
Expansion of a hexanucleotide repeat in non-coding sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778, 21944779). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Function: 
Subcellular location: 
Cytoplasm. Nucleus. Note: Detected in the cytoplasm of neurons from post mortem brain tissue (). Detected in the nucleus in fibroblasts ().
PTM: 
Disease: 
Frontotemporal dementia and/or amyotrophic lateral sclerosis (FTDALS) [MIM:105550]: An autosomal dominant neurodegenerative disorder characterized by adult onset of frontotemporal dementia and/or amyotrophic lateral sclerosis in an affected individual. There is high intrafamilial variation. Frontotemporal dementia is characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Amyotrophic lateral sclerosis is characterized by the death of motor neurons in the brain, brainstem, and spinal cord, resulting in fatal paralysis. Note: The disease is caused by mutations affecting the gene represented in this entry. Caused by a large expansion of a GGGGCC hexanucleotide within the first C9orf72 intron located between the first and the second non-coding exons. The expansion leads to the loss of transcription of one of the two transcripts encoding isoform 1 and to the formation of nuclear RNA foci.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP55358_P050 C9orf72 Antibody (ARP55358_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details
Polyclonal Antibody ARP55359_P050 C9orf72 Antibody (ARP55359_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB09214 C9orf72 antibody - C - terminal region (OAAB09214) Human WB 400ul $289 Details

Show all C9orf72 antibodies


Product Images
C9orf72 antibody - C - terminal region (OAAB09214) in MDA-MB231 cells using Western Blot

Sample Type: MDA-MB231


C9orf72 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP55358 Cat C9orf72 antibody; Felis catus C9orf72 antibody M3VXI7 100.0%
ARP55359 Cat C9orf72 antibody; Felis catus C9orf72 antibody M3VXI7 100.0%
ARP55358 Chimpanzee C9orf72 antibody; Pan troglodytes C9orf72 antibody H2QX41 100.0%
ARP55359 Chimpanzee C9orf72 antibody; Pan troglodytes C9orf72 antibody H2QX41 100.0%
ARP55358 Chinese softshell turtle C9orf72 antibody; Pelodiscus sinensis C9orf72 antibody K7G9S6 100.0%
ARP55359 Chinese softshell turtle C9orf72 antibody; Pelodiscus sinensis C9orf72 antibody K7G9S6 100.0%
ARP55358 Collared flycatcher C9orf72 antibody; Ficedula albicollis C9orf72 antibody U3JEU1 100.0%
ARP55359 Collared flycatcher C9orf72 antibody; Ficedula albicollis C9orf72 antibody U3JEU1 100.0%
ARP55358 Dog C9orf72 antibody; Canis familiaris C9orf72 antibody E2REB5 100.0%
ARP55359 Dog C9orf72 antibody; Canis familiaris C9orf72 antibody E2REB5 100.0%
ARP55358 Domestic duck C9orf72 antibody; Anas platyrhynchos C9orf72 antibody U3I950 100.0%
ARP55359 Domestic duck C9orf72 antibody; Anas platyrhynchos C9orf72 antibody U3I950 100.0%
ARP55359 Duckbill platypus C9orf72 antibody; Ornithorhynchus anatinus C9orf72 antibody F7E7W4 100.0%
ARP55358 Duckbill platypus C9orf72 antibody; Ornithorhynchus anatinus C9orf72 antibody F7E7W4 93.0%
ARP55358 European domestic ferret C9orf72 antibody; Mustela putorius furo C9orf72 antibody M3YWV8 100.0%
ARP55359 European domestic ferret C9orf72 antibody; Mustela putorius furo C9orf72 antibody M3YWV8 100.0%
ARP55358 Giant panda C9orf72 antibody; Ailuropoda melanoleuca C9orf72 antibody D2HTQ5 100.0%
ARP55359 Giant panda C9orf72 antibody; Ailuropoda melanoleuca C9orf72 antibody D2HTQ5 100.0%
ARP55358 Gray short-tailed opossum C9orf72 antibody; Monodelphis domestica C9orf72 antibody F6X6T6 100.0%
ARP55359 Gray short-tailed opossum C9orf72 antibody; Monodelphis domestica C9orf72 antibody F6X6T6 100.0%
ARP55358 Horse C9orf72 antibody; Equus caballus C9orf72 antibody F6Z1K1 100.0%
ARP55359 Horse C9orf72 antibody; Equus caballus C9orf72 antibody F6Z1K1 93.0%
ARP55358 Human C9orf72 antibody; Homo sapiens C9orf72 antibody Q96LT7 100.0%
ARP55359 Human C9orf72 antibody; Homo sapiens C9orf72 antibody Q96LT7 100.0%
ARP55358 Pig C9orf72 antibody; Sus scrofa C9orf72 antibody F1SE55 100.0%
ARP55359 Pig C9orf72 antibody; Sus scrofa C9orf72 antibody F1SE55 100.0%
ARP55358 Rabbit C9orf72 antibody; Oryctolagus cuniculus C9orf72 antibody G1SR57 93.0%
ARP55359 Rabbit C9orf72 antibody; Oryctolagus cuniculus C9orf72 antibody G1SR57 93.0%
ARP55358 Small-eared galago C9orf72 antibody; Otolemur garnettii C9orf72 antibody H0WK96 100.0%
ARP55359 Small-eared galago C9orf72 antibody; Otolemur garnettii C9orf72 antibody H0WK96 100.0%
ARP55359 Southern platyfish C9orf72 antibody; Xiphophorus maculatus C9orf72 antibody M3ZRX6 93.0%
ARP55358 Southern platyfish C9orf72 antibody; Xiphophorus maculatus C9orf72 antibody M3ZRX6 79.0%
ARP55359 Spotted green pufferfish C9orf72 antibody; Tetraodon nigroviridis C9orf72 antibody H3CJC0 92.0%
ARP55358 Spotted green pufferfish C9orf72 antibody; Tetraodon nigroviridis C9orf72 antibody H3CJC0 86.0%
ARP55358 Sumatran orangutan C9orf72 antibody; Pongo abelii C9orf72 antibody H2PRZ5 100.0%
ARP55359 Sumatran orangutan C9orf72 antibody; Pongo abelii C9orf72 antibody H2PRZ5 100.0%
ARP55358 Tasmanian devil C9orf72 antibody; Sarcophilus harrisii C9orf72 antibody G3VK78 100.0%
ARP55359 Tasmanian devil C9orf72 antibody; Sarcophilus harrisii C9orf72 antibody G3VK78 100.0%
ARP55358 Thirteen-lined ground squirrel C9orf72 antibody; Spermophilus tridecemlineatus C9orf72 antibody I3MFZ1 100.0%
ARP55359 Thirteen-lined ground squirrel C9orf72 antibody; Spermophilus tridecemlineatus C9orf72 antibody I3MFZ1 100.0%
ARP55358 Three-spined stickleback C9orf72 antibody; Gasterosteus aculeatus C9orf72 antibody G3NPV4 86.0%
ARP55359 Three-spined stickleback C9orf72 antibody; Gasterosteus aculeatus C9orf72 antibody G3NPV4 85.0%
ARP55358 Western clawed frog C9orf72 antibody; Xenopus tropicalis C9orf72 antibody F6S7Y3 100.0%
ARP55358 Western clawed frog C9orf72 antibody; Xenopus tropicalis C9orf72 antibody F7EC76 100.0%
ARP55358 White-tufted-ear marmoset C9orf72 antibody; Callithrix jacchus C9orf72 antibody F6UMV6 100.0%
ARP55359 White-tufted-ear marmoset C9orf72 antibody; Callithrix jacchus C9orf72 antibody F6UMV6 100.0%
ARP55358 Zebra finch C9orf72 antibody; Taeniopygia guttata C9orf72 antibody H0YT34 100.0%
ARP55359 Zebra finch C9orf72 antibody; Taeniopygia guttata C9orf72 antibody H0YT34 100.0%

Tissue & Cell Line Gene Expression Data