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Gene ID: 729 | C6 Antibody Resource


C6 Antibody Resource
Gene Full Name: 
complement component 6
Uniprot: 
P13671
Protein Name: 
complement component C6
Nucleotide: 
NM_001115131
Alias: 
Ensembl: 
ENSG00000039537
Location: 
5p13
HPRD: 
01956
NCBI Gene: 
729
MIM: 
217050

Summary: 
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]
Function: 
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
Subcellular location: 
Secreted.
PTM: 
Disulfide bond;
Disease: 
Complement component 6 deficiency (C6D) [MIM:612446]: A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Monoclonal Antibody OASA01018 C6 Antibody (OASA01018) Human IHC-AFF, ELISA, FC 0.1mg $515 Details
Polyclonal Antibody OAAB04053 C6 antibody - N-terminal region (OAAB04053) Human WB, IHC, FC, ELISA 400ul $289 Details
Polyclonal Antibody ARP60077_P050 C6 Antibody (ARP60077_P050) Polyclonal Bovine, Dog, Horse, Human, Pig, Rabbit Not tested 50 ug $125 Details
Polyclonal Antibody ARP60078_P050 C6 Antibody (ARP60078_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details
Polyclonal Antibody OAAF03521 C6 Antibody (OAAF03521) Polyclonal Human, Rat WB, IHC, ELISA 100 ug $229 Details

Show all C6 antibodies


Product Images
C6 antibody - N-terminal region (OAAB04053) in human brain carcinoma cells using Immunohistochemistry

Sample Type: human brain carcinoma

C6 antibody - N-terminal region (OAAB04053) in MDA-231 cells using Flow Cytometry

Sample Type: MDA-231

C6 antibody - N-terminal region (OAAB04053) in MDA-MB231 cells using Western Blot

Sample Type: MDA-MB231

C6 Antibody (OAAF03521) in A549, LOVO, HepG2 cells using Western Blot

Sample Type: A549, LOVO, HepG2

C6 Antibody (OAAF03521) in Human heart cells using Immunohistochemistry

Sample Type: Human heart


C6 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP60077 Bornean orangutan C6 antibody; Pongo pygmaeus C6 antibody P61135 100.0%
ARP60078 Bornean orangutan C6 antibody; Pongo pygmaeus C6 antibody P61135 100.0%
ARP60077 Bovine C6 antibody; Bos taurus C6 antibody F1MM86 86.0%
ARP60077 Bovine C6 antibody; Bos taurus C6 antibody Q29RU4 86.0%
ARP60078 Bovine C6 antibody; Bos taurus C6 antibody F1MM86 85.0%
ARP60078 Bovine C6 antibody; Bos taurus C6 antibody Q29RU4 85.0%
ARP60077 Cat C6 antibody; Felis catus C6 antibody M3WLH3 93.0%
ARP60078 Cat C6 antibody; Felis catus C6 antibody M3WLH3 93.0%
ARP60078 Chicken C6 antibody; Gallus gallus C6 antibody B8ZX71 85.0%
ARP60077 Chimpanzee C6 antibody; Pan troglodytes C6 antibody H2QQT6 100.0%
ARP60078 Chimpanzee C6 antibody; Pan troglodytes C6 antibody H2QQT6 100.0%
ARP60077 Chimpanzee C6 antibody; Pan troglodytes C6 antibody P61134 100.0%
ARP60078 Chimpanzee C6 antibody; Pan troglodytes C6 antibody P61134 100.0%
ARP60077 Dog C6 antibody; Canis familiaris C6 antibody E2RGT6 93.0%
ARP60078 Dog C6 antibody; Canis familiaris C6 antibody E2RGT6 86.0%
ARP60078 Domestic duck C6 antibody; Anas platyrhynchos C6 antibody U3IQV8 85.0%
ARP60077 European domestic ferret C6 antibody; Mustela putorius furo C6 antibody M3YSY9 93.0%
ARP60078 European domestic ferret C6 antibody; Mustela putorius furo C6 antibody M3YSY9 93.0%
ARP60077 Giant panda C6 antibody; Ailuropoda melanoleuca C6 antibody G1M9W0 100.0%
ARP60078 Giant panda C6 antibody; Ailuropoda melanoleuca C6 antibody G1M9W0 93.0%
ARP60077 Gray short-tailed opossum C6 antibody; Monodelphis domestica C6 antibody F7BFY4 92.0%
ARP60077 Horse C6 antibody; Equus caballus C6 antibody F6YQL3 100.0%
ARP60078 Horse C6 antibody; Equus caballus C6 antibody F6YQL3 86.0%
ARP60077 Human C6 antibody; Homo sapiens C6 antibody P13671 100.0%
ARP60078 Human C6 antibody; Homo sapiens C6 antibody P13671 100.0%
ARP60078 Mouse C6 antibody; Mus musculus C6 antibody E9Q6D8 92.0%
ARP60078 Mouse C6 antibody; Mus musculus C6 antibody Q8BRY4 92.0%
ARP60078 Mouse C6 antibody; Mus musculus C6 antibody Q91X70 92.0%
ARP60078 Mouse C6 antibody; Mus musculus C6 antibody Q9QXT7 92.0%
ARP60078 Pig C6 antibody; Sus scrofa C6 antibody F1SMI8 93.0%
ARP60077 Rabbit C6 antibody; Oryctolagus cuniculus C6 antibody G1SGF8 100.0%
ARP60078 Rabbit C6 antibody; Oryctolagus cuniculus C6 antibody G1SGF8 100.0%
ARP60078 Rat C6 antibody; Rattus norvegicus C6 antibody F1M7F7 92.0%
ARP60078 Rat C6 antibody; Rattus norvegicus C6 antibody Q811M5 92.0%
ARP60078 Rhesus macaque C6 antibody; Macaca mulatta C6 antibody F7HBE4 100.0%
ARP60077 Rhesus macaque C6 antibody; Macaca mulatta C6 antibody F7HG52 100.0%
ARP60078 Rhesus macaque C6 antibody; Macaca mulatta C6 antibody F7HG52 100.0%
ARP60077 Small-eared galago C6 antibody; Otolemur garnettii C6 antibody H0XE70 100.0%
ARP60078 Small-eared galago C6 antibody; Otolemur garnettii C6 antibody H0XE70 86.0%
ARP60077 Sumatran orangutan C6 antibody; Pongo abelii C6 antibody H2PFF7 100.0%
ARP60078 Sumatran orangutan C6 antibody; Pongo abelii C6 antibody H2PFF7 100.0%
ARP60077 Tasmanian devil C6 antibody; Sarcophilus harrisii C6 antibody G3WFL6 92.0%
ARP60078 Thirteen-lined ground squirrel C6 antibody; Spermophilus tridecemlineatus C6 antibody I3MBA4 93.0%
ARP60077 Western clawed frog C6 antibody; Xenopus tropicalis C6 antibody Q28IR4 90.0%
ARP60077 White-tufted-ear marmoset C6 antibody; Callithrix jacchus C6 antibody F6ZF35 100.0%
ARP60078 White-tufted-ear marmoset C6 antibody; Callithrix jacchus C6 antibody F6ZF35 100.0%
ARP60078 Zebra finch C6 antibody; Taeniopygia guttata C6 antibody H0YVH0 85.0%
ARP60078 Zebrafish C6 antibody; Danio rerio C6 antibody E9QB99 92.0%
ARP60078 Zebrafish C6 antibody; Danio rerio C6 antibody Q6PFT2 92.0%
ARP60078 Zebrafish C6 antibody; Danio rerio C6 antibody E9QEA1 85.0%
ARP60078 Zebrafish C6 antibody; Danio rerio C6 antibody E9QGS7 85.0%
ARP60078 Zebrafish C6 antibody; Danio rerio C6 antibody F1Q611 85.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas210168_at721_B_lymphoblasts5.40013.530Details
BioGPS Gene Atlas210168_atAdipocyte48.60013.530Details
BioGPS Gene Atlas210168_atAdrenalCortex4.45013.530Details
BioGPS Gene Atlas210168_atAdrenalgland3.70013.530Details
BioGPS Gene Atlas210168_atAmygdala4.60013.530Details
BioGPS Gene Atlas210168_atAppendix4.70013.530Details
BioGPS Gene Atlas210168_atAtrioventricularNode3.55013.530Details
BioGPS Gene Atlas210168_atBDCA4+_DentriticCells4.50013.530Details
BioGPS Gene Atlas210168_atBonemarrow7.85013.530Details
BioGPS Gene Atlas210168_atBronchialEpithelialCells4.40013.530Details
BioGPS Gene Atlas210168_atCD105+_Endothelial4.30013.530Details
BioGPS Gene Atlas210168_atCD14+_Monocytes4.55013.530Details
BioGPS Gene Atlas210168_atCD19+_BCells(neg._sel.)4.65013.530Details
BioGPS Gene Atlas210168_atCD33+_Myeloid5.50013.530Details
BioGPS Gene Atlas210168_atCD34+5.30013.530Details
BioGPS Gene Atlas210168_atCD4+_Tcells4.75013.530Details
BioGPS Gene Atlas210168_atCD56+_NKCells4.70013.530Details
BioGPS Gene Atlas210168_atCD71+_EarlyErythroid4.10013.530Details
BioGPS Gene Atlas210168_atCD8+_Tcells4.00013.530Details
BioGPS Gene Atlas210168_atCardiacMyocytes5.50013.530Details
BioGPS Gene Atlas210168_atCaudatenucleus3.90013.530Details
BioGPS Gene Atlas210168_atCerebellum3.55013.530Details
BioGPS Gene Atlas210168_atCerebellumPeduncles5.20013.530Details
BioGPS Gene Atlas210168_atCiliaryGanglion3.25013.530Details
BioGPS Gene Atlas210168_atCingulateCortex4.40013.530Details
BioGPS Gene Atlas210168_atColorectaladenocarcinoma4.40013.530Details
BioGPS Gene Atlas210168_atDorsalRootGanglion3.45013.530Details
BioGPS Gene Atlas210168_atFetalThyroid4.20013.530Details
BioGPS Gene Atlas210168_atFetalbrain4.40013.530Details
BioGPS Gene Atlas210168_atFetalliver41.10013.530Details
BioGPS Gene Atlas210168_atFetallung12.25013.530Details
BioGPS Gene Atlas210168_atGlobusPallidus3.15013.530Details
BioGPS Gene Atlas210168_atHeart6.20013.530Details
BioGPS Gene Atlas210168_atHypothalamus5.25013.530Details
BioGPS Gene Atlas210168_atKidney3.55013.530Details
BioGPS Gene Atlas210168_atLeukemia_chronicMyelogenousK-5623.90013.530Details
BioGPS Gene Atlas210168_atLeukemia_promyelocytic-HL-603.80013.530Details
BioGPS Gene Atlas210168_atLeukemialymphoblastic(MOLT-4)3.65013.530Details
BioGPS Gene Atlas210168_atLiver437.15013.530Details
BioGPS Gene Atlas210168_atLung4.85013.530Details
BioGPS Gene Atlas210168_atLymphnode4.35013.530Details
BioGPS Gene Atlas210168_atLymphoma_burkitts(Daudi)5.60013.530Details
BioGPS Gene Atlas210168_atLymphoma_burkitts(Raji)10.05013.530Details
BioGPS Gene Atlas210168_atMedullaOblongata4.05013.530Details
BioGPS Gene Atlas210168_atOccipitalLobe3.80013.530Details
BioGPS Gene Atlas210168_atOlfactoryBulb3.45013.530Details
BioGPS Gene Atlas210168_atOvary8.60013.530Details
BioGPS Gene Atlas210168_atPancreas35.10013.530Details
BioGPS Gene Atlas210168_atPancreaticIslet198.30013.530Details
BioGPS Gene Atlas210168_atParietalLobe4.50013.530Details
BioGPS Gene Atlas210168_atPituitary5.15013.530Details
BioGPS Gene Atlas210168_atPlacenta4.65013.530Details
BioGPS Gene Atlas210168_atPons4.25013.530Details
BioGPS Gene Atlas210168_atPrefrontalCortex5.45013.530Details
BioGPS Gene Atlas210168_atProstate5.15013.530Details
BioGPS Gene Atlas210168_atSalivarygland3.95013.530Details
BioGPS Gene Atlas210168_atSkeletalMuscle5.85013.530Details
BioGPS Gene Atlas210168_atSkin4.05013.530Details
BioGPS Gene Atlas210168_atSmoothMuscle4.95013.530Details
BioGPS Gene Atlas210168_atSpinalcord4.70013.530Details
BioGPS Gene Atlas210168_atSubthalamicNucleus6.40013.530Details
BioGPS Gene Atlas210168_atSuperiorCervicalGanglion17.40013.530Details
BioGPS Gene Atlas210168_atTemporalLobe3.95013.530Details
BioGPS Gene Atlas210168_atTestis4.85013.530Details
BioGPS Gene Atlas210168_atTestisGermCell3.80013.530Details
BioGPS Gene Atlas210168_atTestisIntersitial3.70013.530Details
BioGPS Gene Atlas210168_atTestisLeydigCell7.30013.530Details
BioGPS Gene Atlas210168_atTestisSeminiferousTubule7.90013.530Details
BioGPS Gene Atlas210168_atThalamus4.35013.530Details
BioGPS Gene Atlas210168_atThymus3.45013.530Details
BioGPS Gene Atlas210168_atThyroid5.60013.530Details
BioGPS Gene Atlas210168_atTongue9.50013.530Details
BioGPS Gene Atlas210168_atTonsil4.35013.530Details
BioGPS Gene Atlas210168_atTrachea3.80013.530Details
BioGPS Gene Atlas210168_atTrigeminalGanglion11.80013.530Details
BioGPS Gene Atlas210168_atUterus3.60013.530Details
BioGPS Gene Atlas210168_atUterusCorpus6.20013.530Details
BioGPS Gene Atlas210168_atWholeBlood4.85013.530Details
BioGPS Gene Atlas210168_atWholebrain3.70013.530Details
BioGPS Gene Atlas210168_atcolon5.40013.530Details
BioGPS Gene Atlas210168_atpineal_day5.30013.530Details
BioGPS Gene Atlas210168_atpineal_night5.22013.530Details
BioGPS Gene Atlas210168_atretina5.55013.530Details
BioGPS Gene Atlas210168_atsmall_intestine4.25013.530Details
BioGPS NCI60210168_at7863.5643.650Details
BioGPS NCI60210168_atA1723.4043.650Details
BioGPS NCI60210168_atA2043.4703.650Details
BioGPS NCI60210168_atA3613.5313.650Details
BioGPS NCI60210168_atA4983.5083.650Details
BioGPS NCI60210168_atA5493.5433.650Details
BioGPS NCI60210168_atACC33.9113.650Details
BioGPS NCI60210168_atACHN3.3693.650Details
BioGPS NCI60210168_atALVA314.0263.650Details
BioGPS NCI60210168_atCAKI13.5793.650Details
BioGPS NCI60210168_atCCRT CEM5.2883.650Details
BioGPS NCI60210168_atCOLO2053.4863.650Details
BioGPS NCI60210168_atDLD13.4683.650Details
BioGPS NCI60210168_atDU1453.2853.650Details
BioGPS NCI60210168_atEKVX3.3213.650Details
BioGPS NCI60210168_atGM1333.5523.650Details
BioGPS NCI60210168_atGM16003.5913.650Details
BioGPS NCI60210168_atGM23133.5393.650Details
BioGPS NCI60210168_atGM23453.5143.650Details
BioGPS NCI60210168_atGM24933.5753.650Details
BioGPS NCI60210168_atGM974.5663.650Details
BioGPS NCI60210168_atHCC29983.3603.650Details
BioGPS NCI60210168_atHCT1163.4903.650Details
BioGPS NCI60210168_atHCT153.3773.650Details
BioGPS NCI60210168_atHEK 293 T-rex3.7303.650Details
BioGPS NCI60210168_atHEK 293T3.5303.650Details
BioGPS NCI60210168_atHEK2933.5863.650Details
BioGPS NCI60210168_atHELA3.2693.650Details
BioGPS NCI60210168_atHEPG23.4923.650Details
BioGPS NCI60210168_atHL603.8773.650Details
BioGPS NCI60210168_atHOP623.5093.650Details
BioGPS NCI60210168_atHOP923.3543.650Details
BioGPS NCI60210168_atHS578T3.4713.650Details
BioGPS NCI60210168_atHSG3.4403.650Details
BioGPS NCI60210168_atHT10803.4373.650Details
BioGPS NCI60210168_atHT293.6233.650Details
BioGPS NCI60210168_atIGROV13.4793.650Details
BioGPS NCI60210168_atIOSE803.4963.650Details
BioGPS NCI60210168_atJURKAT3.4893.650Details
BioGPS NCI60210168_atK5623.6083.650Details
BioGPS NCI60210168_atKM123.5673.650Details
BioGPS NCI60210168_atLN183.4163.650Details
BioGPS NCI60210168_atLNCAP3.4983.650Details
BioGPS NCI60210168_atLOX IMVI3.5033.650Details
BioGPS NCI60210168_atM143.4703.650Details
BioGPS NCI60210168_atMALME 3M3.6103.650Details
BioGPS NCI60210168_atMCF73.4293.650Details
BioGPS NCI60210168_atMD MB2313.5223.650Details
BioGPS NCI60210168_atMDA MB4353.5853.650Details
BioGPS NCI60210168_atMOLT43.5593.650Details
BioGPS NCI60210168_atNCI 4603.5633.650Details
BioGPS NCI60210168_atNCI H2263.6833.650Details
BioGPS NCI60210168_atNCI H233.4973.650Details
BioGPS NCI60210168_atNCI H322M3.5163.650Details
BioGPS NCI60210168_atNCVADR RES3.2843.650Details
BioGPS NCI60210168_atOVCAR33.5843.650Details
BioGPS NCI60210168_atOVCAR43.4893.650Details
BioGPS NCI60210168_atOVCAR53.4643.650Details
BioGPS NCI60210168_atOVCAR83.3773.650Details
BioGPS NCI60210168_atPANC13.5063.650Details
BioGPS NCI60210168_atRL73.5473.650Details
BioGPS NCI60210168_atRPMI 82263.5333.650Details
BioGPS NCI60210168_atRS118463.6013.650Details
BioGPS NCI60210168_atRXF3933.4983.650Details
BioGPS NCI60210168_atSAOS23.5333.650Details
BioGPS NCI60210168_atSF2683.4823.650Details
BioGPS NCI60210168_atSF2953.4533.650Details
BioGPS NCI60210168_atSF5393.3743.650Details
BioGPS NCI60210168_atSHSYSY+RA3.4553.650Details
BioGPS NCI60210168_atSHSYSY-RA3.4893.650Details
BioGPS NCI60210168_atSKMEL23.4893.650Details
BioGPS NCI60210168_atSKMEL283.5053.650Details
BioGPS NCI60210168_atSKMEL53.4223.650Details
BioGPS NCI60210168_atSKOV33.5403.650Details
BioGPS NCI60210168_atSN12C3.4963.650Details
BioGPS NCI60210168_atSNB193.3863.650Details
BioGPS NCI60210168_atSNB753.3863.650Details
BioGPS NCI60210168_atSR3.5493.650Details
BioGPS NCI60210168_atSW6203.4953.650Details
BioGPS NCI60210168_atT243.5613.650Details
BioGPS NCI60210168_atT3M43.5693.650Details
BioGPS NCI60210168_atTK103.4563.650Details
BioGPS NCI60210168_atU1183.4013.650Details
BioGPS NCI60210168_atU1383.4013.650Details
BioGPS NCI60210168_atU20S8.4513.650Details
BioGPS NCI60210168_atU2513.4713.650Details
BioGPS NCI60210168_atU873.4503.650Details
BioGPS NCI60210168_atUACC2573.4633.650Details
BioGPS NCI60210168_atUACC623.5383.650Details
BioGPS NCI60210168_atUO313.4383.650Details
BioGPS NCI60210168_atZR75_13.5613.650Details
BioGPS NCI60210168_atastrocytes4.4153.650Details
BioGPS NCI60210168_athuh-73.8263.650Details