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Gene ID: 722 | C4BPA Antibody Resource


C4BPA Antibody Resource
Gene Full Name: 
complement component 4 binding protein, alpha
Uniprot: 
P04003
Protein Name: 
C4b-binding protein alpha chain
Nucleotide: 
XM_005273252
Alias: 
PRP;C4BP;
Ensembl: 
ENSG00000123838
Location: 
1q32
HPRD: 
00403
NCBI Gene: 
722
MIM: 
120830

Summary: 
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. [provided by RefSeq, Jul 2008]
Function: 
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
Subcellular location: 
Secreted.
PTM: 
Disulfide bond;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP41420_P050 C4BPA antibody - middle region (ARP41420_P050) Polyclonal Human WB 50ug $289 Details
Monoclonal Antibody OASA01011 C4BPA Antibody (OASA01011) Human ELISA 0.1mg $540 Details
Polyclonal Antibody OASA09147 C4BPA Antibody (OASA09147) Human IHC-AFF 1ml $600 Details
Polyclonal Antibody OAAB03368 C4BPA antibody - C-terminal region (OAAB03368) Human WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP41419_P050 C4BPA Antibody (ARP41419_P050) Polyclonal Human Not tested 50 ug $125 Details

Show all C4BPA antibodies


Product Images

Sample Type: HepG2 Whole Cell

C4BPA antibody - middle region (ARP41420_P050) in Human MCF-7 cells using Western Blot

Sample Type: Human MCF-7

C4BPA antibody - C-terminal region (OAAB03368) in human hepatocarcinoma cells using Immunohistochemistry

Sample Type: human hepatocarcinoma

C4BPA antibody - C-terminal region (OAAB03368) in WiDr cells using Western Blot

Sample Type: WiDr


C4BPA Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP41419 Chimpanzee C4BPA antibody; Pan troglodytes C4BPA antibody H2Q114 100.0%
ARP41420 Chimpanzee C4BPA antibody; Pan troglodytes C4BPA antibody H2Q114 93.0%
ARP41419 Human C4BPA antibody; Homo sapiens C4BPA antibody P04003 100.0%
ARP41420 Human C4BPA antibody; Homo sapiens C4BPA antibody P04003 100.0%
ARP41419 Human C4BPA antibody; Homo sapiens C4BPA antibody Q5VVQ8 100.0%
ARP41420 Human C4BPA antibody; Homo sapiens C4BPA antibody Q5VVQ8 100.0%
ARP41419 Northern white-cheeked gibbon C4BPA antibody; Nomascus leucogenys C4BPA antibody G1QJR5 100.0%
ARP41420 Northern white-cheeked gibbon C4BPA antibody; Nomascus leucogenys C4BPA antibody G1QJR5 86.0%
ARP41419 Rhesus macaque C4BPA antibody; Macaca mulatta C4BPA antibody F6RNZ2 93.0%
ARP41420 Rhesus macaque C4BPA antibody; Macaca mulatta C4BPA antibody F6RNZ2 93.0%
ARP41419 Sumatran orangutan C4BPA antibody; Pongo abelii C4BPA antibody H2N3W0 100.0%
ARP41420 Sumatran orangutan C4BPA antibody; Pongo abelii C4BPA antibody H2N3W0 100.0%
ARP41420 White-tufted-ear marmoset C4BPA antibody; Callithrix jacchus C4BPA antibody F6SQK3 79.0%
ARP41420 White-tufted-ear marmoset C4BPA antibody; Callithrix jacchus C4BPA antibody F6SRJ4 79.0%
ARP41420 White-tufted-ear marmoset C4BPA antibody; Callithrix jacchus C4BPA antibody U3D0Y2 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas205654_at721_B_lymphoblasts5.65018.360Details
BioGPS Gene Atlas205654_atAdipocyte4.85018.360Details
BioGPS Gene Atlas205654_atAdrenalCortex5.05018.360Details
BioGPS Gene Atlas205654_atAdrenalgland4.15018.360Details
BioGPS Gene Atlas205654_atAmygdala5.20018.360Details
BioGPS Gene Atlas205654_atAppendix5.30018.360Details
BioGPS Gene Atlas205654_atAtrioventricularNode4.85018.360Details
BioGPS Gene Atlas205654_atBDCA4+_DentriticCells5.10018.360Details
BioGPS Gene Atlas205654_atBonemarrow4.85018.360Details
BioGPS Gene Atlas205654_atBronchialEpithelialCells4.70018.360Details
BioGPS Gene Atlas205654_atCD105+_Endothelial5.25018.360Details
BioGPS Gene Atlas205654_atCD14+_Monocytes5.85018.360Details
BioGPS Gene Atlas205654_atCD19+_BCells(neg._sel.)4.95018.360Details
BioGPS Gene Atlas205654_atCD33+_Myeloid6.20018.360Details
BioGPS Gene Atlas205654_atCD34+6.10018.360Details
BioGPS Gene Atlas205654_atCD4+_Tcells5.00018.360Details
BioGPS Gene Atlas205654_atCD56+_NKCells5.80018.360Details
BioGPS Gene Atlas205654_atCD71+_EarlyErythroid4.55018.360Details
BioGPS Gene Atlas205654_atCD8+_Tcells4.50018.360Details
BioGPS Gene Atlas205654_atCardiacMyocytes6.20018.360Details
BioGPS Gene Atlas205654_atCaudatenucleus4.30018.360Details
BioGPS Gene Atlas205654_atCerebellum3.90018.360Details
BioGPS Gene Atlas205654_atCerebellumPeduncles5.80018.360Details
BioGPS Gene Atlas205654_atCiliaryGanglion3.55018.360Details
BioGPS Gene Atlas205654_atCingulateCortex4.90018.360Details
BioGPS Gene Atlas205654_atColorectaladenocarcinoma4.90018.360Details
BioGPS Gene Atlas205654_atDorsalRootGanglion6.00018.360Details
BioGPS Gene Atlas205654_atFetalThyroid4.70018.360Details
BioGPS Gene Atlas205654_atFetalbrain4.90018.360Details
BioGPS Gene Atlas205654_atFetalliver9.00018.360Details
BioGPS Gene Atlas205654_atFetallung22.65018.360Details
BioGPS Gene Atlas205654_atGlobusPallidus3.55018.360Details
BioGPS Gene Atlas205654_atHeart6.10018.360Details
BioGPS Gene Atlas205654_atHypothalamus5.10018.360Details
BioGPS Gene Atlas205654_atKidney3.85018.360Details
BioGPS Gene Atlas205654_atLeukemia_chronicMyelogenousK-5624.40018.360Details
BioGPS Gene Atlas205654_atLeukemia_promyelocytic-HL-604.20018.360Details
BioGPS Gene Atlas205654_atLeukemialymphoblastic(MOLT-4)3.90018.360Details
BioGPS Gene Atlas205654_atLiver797.65018.360Details
BioGPS Gene Atlas205654_atLung277.55018.360Details
BioGPS Gene Atlas205654_atLymphnode5.05018.360Details
BioGPS Gene Atlas205654_atLymphoma_burkitts(Daudi)6.10018.360Details
BioGPS Gene Atlas205654_atLymphoma_burkitts(Raji)7.00018.360Details
BioGPS Gene Atlas205654_atMedullaOblongata4.45018.360Details
BioGPS Gene Atlas205654_atOccipitalLobe4.35018.360Details
BioGPS Gene Atlas205654_atOlfactoryBulb3.80018.360Details
BioGPS Gene Atlas205654_atOvary3.65018.360Details
BioGPS Gene Atlas205654_atPancreas18.05018.360Details
BioGPS Gene Atlas205654_atPancreaticIslet76.85018.360Details
BioGPS Gene Atlas205654_atParietalLobe5.15018.360Details
BioGPS Gene Atlas205654_atPituitary5.65018.360Details
BioGPS Gene Atlas205654_atPlacenta5.90018.360Details
BioGPS Gene Atlas205654_atPons4.75018.360Details
BioGPS Gene Atlas205654_atPrefrontalCortex5.90018.360Details
BioGPS Gene Atlas205654_atProstate5.95018.360Details
BioGPS Gene Atlas205654_atSalivarygland3.95018.360Details
BioGPS Gene Atlas205654_atSkeletalMuscle5.75018.360Details
BioGPS Gene Atlas205654_atSkin4.45018.360Details
BioGPS Gene Atlas205654_atSmoothMuscle5.55018.360Details
BioGPS Gene Atlas205654_atSpinalcord5.20018.360Details
BioGPS Gene Atlas205654_atSubthalamicNucleus4.40018.360Details
BioGPS Gene Atlas205654_atSuperiorCervicalGanglion6.00018.360Details
BioGPS Gene Atlas205654_atTemporalLobe4.40018.360Details
BioGPS Gene Atlas205654_atTestis4.45018.360Details
BioGPS Gene Atlas205654_atTestisGermCell4.10018.360Details
BioGPS Gene Atlas205654_atTestisIntersitial5.45018.360Details
BioGPS Gene Atlas205654_atTestisLeydigCell4.80018.360Details
BioGPS Gene Atlas205654_atTestisSeminiferousTubule4.20018.360Details
BioGPS Gene Atlas205654_atThalamus4.90018.360Details
BioGPS Gene Atlas205654_atThymus3.85018.360Details
BioGPS Gene Atlas205654_atThyroid6.20018.360Details
BioGPS Gene Atlas205654_atTongue5.90018.360Details
BioGPS Gene Atlas205654_atTonsil4.70018.360Details
BioGPS Gene Atlas205654_atTrachea4.00018.360Details
BioGPS Gene Atlas205654_atTrigeminalGanglion6.25018.360Details
BioGPS Gene Atlas205654_atUterus4.85018.360Details
BioGPS Gene Atlas205654_atUterusCorpus4.65018.360Details
BioGPS Gene Atlas205654_atWholeBlood5.45018.360Details
BioGPS Gene Atlas205654_atWholebrain4.35018.360Details
BioGPS Gene Atlas205654_atcolon4.75018.360Details
BioGPS Gene Atlas205654_atpineal_day5.90018.360Details
BioGPS Gene Atlas205654_atpineal_night5.84018.360Details
BioGPS Gene Atlas205654_atretina5.77518.360Details
BioGPS Gene Atlas205654_atsmall_intestine4.65018.360Details
BioGPS NCI60205654_at7864.1267.000Details
BioGPS NCI60205654_atA1723.9187.000Details
BioGPS NCI60205654_atA2043.9977.000Details
BioGPS NCI60205654_atA3614.0887.000Details
BioGPS NCI60205654_atA4984.0017.000Details
BioGPS NCI60205654_atA5494.1427.000Details
BioGPS NCI60205654_atACC3167.6577.000Details
BioGPS NCI60205654_atACHN3.7337.000Details
BioGPS NCI60205654_atALVA314.2657.000Details
BioGPS NCI60205654_atCAKI14.1387.000Details
BioGPS NCI60205654_atCCRT CEM4.3877.000Details
BioGPS NCI60205654_atCOLO20524.6807.000Details
BioGPS NCI60205654_atDLD13.9277.000Details
BioGPS NCI60205654_atDU1453.8987.000Details
BioGPS NCI60205654_atEKVX8.9357.000Details
BioGPS NCI60205654_atGM1334.1417.000Details
BioGPS NCI60205654_atGM16004.4557.000Details
BioGPS NCI60205654_atGM23134.2457.000Details
BioGPS NCI60205654_atGM23454.0427.000Details
BioGPS NCI60205654_atGM24934.3847.000Details
BioGPS NCI60205654_atGM974.7797.000Details
BioGPS NCI60205654_atHCC29983.6377.000Details
BioGPS NCI60205654_atHCT1164.0117.000Details
BioGPS NCI60205654_atHCT153.8127.000Details
BioGPS NCI60205654_atHEK 293 T-rex4.2617.000Details
BioGPS NCI60205654_atHEK 293T4.0777.000Details
BioGPS NCI60205654_atHEK2934.4477.000Details
BioGPS NCI60205654_atHELA3.9347.000Details
BioGPS NCI60205654_atHEPG2109.8987.000Details
BioGPS NCI60205654_atHL604.1557.000Details
BioGPS NCI60205654_atHOP624.0107.000Details
BioGPS NCI60205654_atHOP923.8717.000Details
BioGPS NCI60205654_atHS578T3.9487.000Details
BioGPS NCI60205654_atHSG4.9107.000Details
BioGPS NCI60205654_atHT10803.9407.000Details
BioGPS NCI60205654_atHT294.4777.000Details
BioGPS NCI60205654_atIGROV13.9467.000Details
BioGPS NCI60205654_atIOSE803.9767.000Details
BioGPS NCI60205654_atJURKAT4.0177.000Details
BioGPS NCI60205654_atK5624.4417.000Details
BioGPS NCI60205654_atKM124.1577.000Details
BioGPS NCI60205654_atLN1814.3577.000Details
BioGPS NCI60205654_atLNCAP4.0037.000Details
BioGPS NCI60205654_atLOX IMVI3.9877.000Details
BioGPS NCI60205654_atM143.9877.000Details
BioGPS NCI60205654_atMALME 3M4.2027.000Details
BioGPS NCI60205654_atMCF73.8927.000Details
BioGPS NCI60205654_atMD MB2314.0627.000Details
BioGPS NCI60205654_atMDA MB4354.2227.000Details
BioGPS NCI60205654_atMOLT44.2457.000Details
BioGPS NCI60205654_atNCI 4604.1177.000Details
BioGPS NCI60205654_atNCI H2264.1047.000Details
BioGPS NCI60205654_atNCI H233.9797.000Details
BioGPS NCI60205654_atNCI H322M4.0007.000Details
BioGPS NCI60205654_atNCVADR RES3.7627.000Details
BioGPS NCI60205654_atOVCAR34.1767.000Details
BioGPS NCI60205654_atOVCAR43.9817.000Details
BioGPS NCI60205654_atOVCAR53.9027.000Details
BioGPS NCI60205654_atOVCAR83.7987.000Details
BioGPS NCI60205654_atPANC14.0737.000Details
BioGPS NCI60205654_atRL74.1457.000Details
BioGPS NCI60205654_atRPMI 82264.0817.000Details
BioGPS NCI60205654_atRS118464.3507.000Details
BioGPS NCI60205654_atRXF3933.9827.000Details
BioGPS NCI60205654_atSAOS24.0637.000Details
BioGPS NCI60205654_atSF2684.0067.000Details
BioGPS NCI60205654_atSF2953.9567.000Details
BioGPS NCI60205654_atSF5393.8047.000Details
BioGPS NCI60205654_atSHSYSY+RA3.8547.000Details
BioGPS NCI60205654_atSHSYSY-RA3.9657.000Details
BioGPS NCI60205654_atSKMEL23.9987.000Details
BioGPS NCI60205654_atSKMEL284.0177.000Details
BioGPS NCI60205654_atSKMEL53.8967.000Details
BioGPS NCI60205654_atSKOV34.1237.000Details
BioGPS NCI60205654_atSN12C3.9857.000Details
BioGPS NCI60205654_atSNB193.7837.000Details
BioGPS NCI60205654_atSNB753.9727.000Details
BioGPS NCI60205654_atSR4.1797.000Details
BioGPS NCI60205654_atSW6204.1167.000Details
BioGPS NCI60205654_atT244.1477.000Details
BioGPS NCI60205654_atT3M44.1597.000Details
BioGPS NCI60205654_atTK103.9637.000Details
BioGPS NCI60205654_atU1183.9227.000Details
BioGPS NCI60205654_atU1383.9387.000Details
BioGPS NCI60205654_atU20S4.6367.000Details
BioGPS NCI60205654_atU2513.9527.000Details
BioGPS NCI60205654_atU873.9077.000Details
BioGPS NCI60205654_atUACC2573.9387.000Details
BioGPS NCI60205654_atUACC624.0877.000Details
BioGPS NCI60205654_atUO313.8537.000Details
BioGPS NCI60205654_atZR75_14.1187.000Details
BioGPS NCI60205654_atastrocytes4.0967.000Details
BioGPS NCI60205654_athuh-74.2657.000Details