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Gene ID: 716 | C1S Antibody Resource


C1S Antibody Resource
Gene Full Name: 
complement component 1, s subcomponent
Uniprot: 
P09871
Protein Name: 
complement C1s subcomponent
Nucleotide: 
XM_005253761
Alias: 
Ensembl: 
ENSG00000182326
Location: 
12p13
HPRD: 
00397
NCBI Gene: 
716
MIM: 
120580

Summary: 
This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]
Function: 
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
Subcellular location: 
PTM: 
Disulfide bond;
Disease: 
Complement component C1s deficiency (C1SD) [MIM:613783]: A rare defect resulting in C1 deficiency and impaired activation of the complement classical pathway. C1 deficiency generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB00115 C1S antibody - center region (OAAB00115) Human WB, ELISA 400ul $289 Details
Polyclonal Antibody ARP60069_P050 C1S Antibody (ARP60069_P050) Polyclonal Human, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP60070_P050 C1S Antibody (ARP60070_P050) Polyclonal Dog, Human Not tested 50 ug $125 Details
Polyclonal Antibody OAEC01685 C1S (heavy chain,Cleaved-Arg437)Antibody (OAEC01685) Human WB, ELISA 100ug $229 Details
Polyclonal Antibody OAAF05368 C1S (heavy chain, Cleaved-Arg437) Antibody (OAAF05368) Polyclonal Human WB, ELISA 100 ug $229 Details
Polyclonal Antibody OAAF03519 C1S Antibody (OAAF03519) Polyclonal Human WB, IHC, ELISA 100 ug $229 Details

Show all C1S antibodies


Product Images
C1S Antibody (OAAF03519) in Human breast carcinoma cells using Immunohistochemistry

Sample Type: Human breast carcinoma

C1S Antibody (OAAF03519) in Jurkat, COLO cells using Western Blot

Sample Type: Jurkat, COLO

C1S (heavy chain, Cleaved-Arg437) Antibody (OAAF05368) in 293 cells using Western Blot

Sample Type: 293

C1S (heavy chain,Cleaved-Arg437)Antibody (OAEC01685) in 293 cells using Western Blot

Sample Type: 293


C1S Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP41573 Chicken C1S antibody; Gallus gallus C1S antibody F1N803 83.0%
ARP60069 Chimpanzee C1S antibody; Pan troglodytes C1S antibody H2RB03 100.0%
ARP60070 Chimpanzee C1S antibody; Pan troglodytes C1S antibody H2RB03 100.0%
ARP60069 Chimpanzee C1S antibody; Pan troglodytes C1S antibody K7AR52 100.0%
ARP60070 Chimpanzee C1S antibody; Pan troglodytes C1S antibody K7AR52 100.0%
ARP60069 Chimpanzee C1S antibody; Pan troglodytes C1S antibody K7DER1 100.0%
ARP60070 Chimpanzee C1S antibody; Pan troglodytes C1S antibody K7DER1 100.0%
ARP60069 Chimpanzee C1S antibody; Pan troglodytes C1S antibody K7DIF3 100.0%
ARP60070 Chimpanzee C1S antibody; Pan troglodytes C1S antibody K7DIF3 100.0%
ARP60070 Giant panda C1S antibody; Ailuropoda melanoleuca C1S antibody G1M541 85.0%
ARP60069 Giant panda C1S antibody; Ailuropoda melanoleuca C1S antibody G1M541 79.0%
ARP60070 Human C1S antibody; Homo sapiens C1S antibody F5H7T4 100.0%
ARP60069 Human C1S antibody; Homo sapiens C1S antibody F8WCZ6 100.0%
ARP60070 Human C1S antibody; Homo sapiens C1S antibody F8WCZ6 100.0%
ARP60070 Human C1S antibody; Homo sapiens C1S antibody H0Y5D1 100.0%
ARP60069 Human C1S antibody; Homo sapiens C1S antibody P09871 100.0%
ARP60070 Human C1S antibody; Homo sapiens C1S antibody P09871 100.0%
ARP60069 Northern white-cheeked gibbon C1S antibody; Nomascus leucogenys C1S antibody G1QZ50 100.0%
ARP60070 Northern white-cheeked gibbon C1S antibody; Nomascus leucogenys C1S antibody G1QZ50 100.0%
ARP60069 Rabbit C1S antibody; Oryctolagus cuniculus C1S antibody G1T7G7 79.0%
ARP60069 Rat C1S antibody; Rattus norvegicus C1S antibody D4A1S0 86.0%
ARP60069 Rat C1S antibody; Rattus norvegicus C1S antibody G3V7L3 86.0%
ARP60069 Rat C1S antibody; Rattus norvegicus C1S antibody Q6P6T1 86.0%
ARP60069 Rhesus macaque C1S antibody; Macaca mulatta C1S antibody H9FZ52 100.0%
ARP60070 Rhesus macaque C1S antibody; Macaca mulatta C1S antibody H9FZ52 86.0%
ARP60069 Small-eared galago C1S antibody; Otolemur garnettii C1S antibody H0WVC2 92.0%
ARP60070 Small-eared galago C1S antibody; Otolemur garnettii C1S antibody H0WVC2 92.0%
ARP60069 Sumatran orangutan C1S antibody; Pongo abelii C1S antibody H2NGB6 100.0%
ARP60070 Sumatran orangutan C1S antibody; Pongo abelii C1S antibody H2NGB6 100.0%
ARP60070 White-tufted-ear marmoset C1S antibody; Callithrix jacchus C1S antibody F6VJE5 100.0%
ARP60070 White-tufted-ear marmoset C1S antibody; Callithrix jacchus C1S antibody U3CXH6 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas208747_s_at721_B_lymphoblasts16.300356.410Details
BioGPS Gene Atlas208747_s_atAdipocyte3242.100356.410Details
BioGPS Gene Atlas208747_s_atAdrenalCortex273.100356.410Details
BioGPS Gene Atlas208747_s_atAdrenalgland311.550356.410Details
BioGPS Gene Atlas208747_s_atAmygdala16.950356.410Details
BioGPS Gene Atlas208747_s_atAppendix1032.850356.410Details
BioGPS Gene Atlas208747_s_atAtrioventricularNode749.150356.410Details
BioGPS Gene Atlas208747_s_atBDCA4+_DentriticCells7.750356.410Details
BioGPS Gene Atlas208747_s_atBonemarrow14.450356.410Details
BioGPS Gene Atlas208747_s_atBronchialEpithelialCells9.750356.410Details
BioGPS Gene Atlas208747_s_atCD105+_Endothelial64.950356.410Details
BioGPS Gene Atlas208747_s_atCD14+_Monocytes7.050356.410Details
BioGPS Gene Atlas208747_s_atCD19+_BCells(neg._sel.)13.650356.410Details
BioGPS Gene Atlas208747_s_atCD33+_Myeloid16.650356.410Details
BioGPS Gene Atlas208747_s_atCD34+18.500356.410Details
BioGPS Gene Atlas208747_s_atCD4+_Tcells10.600356.410Details
BioGPS Gene Atlas208747_s_atCD56+_NKCells15.500356.410Details
BioGPS Gene Atlas208747_s_atCD71+_EarlyErythroid37.750356.410Details
BioGPS Gene Atlas208747_s_atCD8+_Tcells10.500356.410Details
BioGPS Gene Atlas208747_s_atCardiacMyocytes114.050356.410Details
BioGPS Gene Atlas208747_s_atCaudatenucleus11.550356.410Details
BioGPS Gene Atlas208747_s_atCerebellum11.600356.410Details
BioGPS Gene Atlas208747_s_atCerebellumPeduncles14.500356.410Details
BioGPS Gene Atlas208747_s_atCiliaryGanglion526.400356.410Details
BioGPS Gene Atlas208747_s_atCingulateCortex13.800356.410Details
BioGPS Gene Atlas208747_s_atColorectaladenocarcinoma9.200356.410Details
BioGPS Gene Atlas208747_s_atDorsalRootGanglion358.600356.410Details
BioGPS Gene Atlas208747_s_atFetalThyroid699.700356.410Details
BioGPS Gene Atlas208747_s_atFetalbrain16.900356.410Details
BioGPS Gene Atlas208747_s_atFetalliver208.500356.410Details
BioGPS Gene Atlas208747_s_atFetallung1271.550356.410Details
BioGPS Gene Atlas208747_s_atGlobusPallidus10.450356.410Details
BioGPS Gene Atlas208747_s_atHeart25.450356.410Details
BioGPS Gene Atlas208747_s_atHypothalamus73.750356.410Details
BioGPS Gene Atlas208747_s_atKidney17.450356.410Details
BioGPS Gene Atlas208747_s_atLeukemia_chronicMyelogenousK-5629.400356.410Details
BioGPS Gene Atlas208747_s_atLeukemia_promyelocytic-HL-6011.350356.410Details
BioGPS Gene Atlas208747_s_atLeukemialymphoblastic(MOLT-4)11.400356.410Details
BioGPS Gene Atlas208747_s_atLiver1646.750356.410Details
BioGPS Gene Atlas208747_s_atLung670.800356.410Details
BioGPS Gene Atlas208747_s_atLymphnode994.100356.410Details
BioGPS Gene Atlas208747_s_atLymphoma_burkitts(Daudi)18.100356.410Details
BioGPS Gene Atlas208747_s_atLymphoma_burkitts(Raji)11.550356.410Details
BioGPS Gene Atlas208747_s_atMedullaOblongata13.400356.410Details
BioGPS Gene Atlas208747_s_atOccipitalLobe13.400356.410Details
BioGPS Gene Atlas208747_s_atOlfactoryBulb1034.400356.410Details
BioGPS Gene Atlas208747_s_atOvary2315.550356.410Details
BioGPS Gene Atlas208747_s_atPancreas251.650356.410Details
BioGPS Gene Atlas208747_s_atPancreaticIslet826.600356.410Details
BioGPS Gene Atlas208747_s_atParietalLobe13.500356.410Details
BioGPS Gene Atlas208747_s_atPituitary96.300356.410Details
BioGPS Gene Atlas208747_s_atPlacenta117.500356.410Details
BioGPS Gene Atlas208747_s_atPons30.950356.410Details
BioGPS Gene Atlas208747_s_atPrefrontalCortex49.500356.410Details
BioGPS Gene Atlas208747_s_atProstate209.450356.410Details
BioGPS Gene Atlas208747_s_atSalivarygland612.700356.410Details
BioGPS Gene Atlas208747_s_atSkeletalMuscle59.600356.410Details
BioGPS Gene Atlas208747_s_atSkin307.100356.410Details
BioGPS Gene Atlas208747_s_atSmoothMuscle1050.600356.410Details
BioGPS Gene Atlas208747_s_atSpinalcord240.750356.410Details
BioGPS Gene Atlas208747_s_atSubthalamicNucleus23.550356.410Details
BioGPS Gene Atlas208747_s_atSuperiorCervicalGanglion265.950356.410Details
BioGPS Gene Atlas208747_s_atTemporalLobe13.000356.410Details
BioGPS Gene Atlas208747_s_atTestis115.050356.410Details
BioGPS Gene Atlas208747_s_atTestisGermCell587.300356.410Details
BioGPS Gene Atlas208747_s_atTestisIntersitial212.650356.410Details
BioGPS Gene Atlas208747_s_atTestisLeydigCell273.200356.410Details
BioGPS Gene Atlas208747_s_atTestisSeminiferousTubule561.650356.410Details
BioGPS Gene Atlas208747_s_atThalamus13.100356.410Details
BioGPS Gene Atlas208747_s_atThymus470.500356.410Details
BioGPS Gene Atlas208747_s_atThyroid480.350356.410Details
BioGPS Gene Atlas208747_s_atTongue504.150356.410Details
BioGPS Gene Atlas208747_s_atTonsil521.350356.410Details
BioGPS Gene Atlas208747_s_atTrachea441.150356.410Details
BioGPS Gene Atlas208747_s_atTrigeminalGanglion591.600356.410Details
BioGPS Gene Atlas208747_s_atUterus750.500356.410Details
BioGPS Gene Atlas208747_s_atUterusCorpus519.350356.410Details
BioGPS Gene Atlas208747_s_atWholeBlood11.050356.410Details
BioGPS Gene Atlas208747_s_atWholebrain12.100356.410Details
BioGPS Gene Atlas208747_s_atcolon488.600356.410Details
BioGPS Gene Atlas208747_s_atpineal_day133.620356.410Details
BioGPS Gene Atlas208747_s_atpineal_night165.320356.410Details
BioGPS Gene Atlas208747_s_atretina1511.675356.410Details
BioGPS Gene Atlas208747_s_atsmall_intestine868.100356.410Details
BioGPS NCI60208747_s_at7864.835356.920Details
BioGPS NCI60208747_s_atA172437.995356.920Details
BioGPS NCI60208747_s_atA204622.777356.920Details
BioGPS NCI60208747_s_atA3614.794356.920Details
BioGPS NCI60208747_s_atA4981879.230356.920Details
BioGPS NCI60208747_s_atA549609.854356.920Details
BioGPS NCI60208747_s_atACC3898.637356.920Details
BioGPS NCI60208747_s_atACHN37.736356.920Details
BioGPS NCI60208747_s_atALVA314.989356.920Details
BioGPS NCI60208747_s_atCAKI1789.510356.920Details
BioGPS NCI60208747_s_atCCRT CEM5.468356.920Details
BioGPS NCI60208747_s_atCOLO2054.847356.920Details
BioGPS NCI60208747_s_atDLD14.690356.920Details
BioGPS NCI60208747_s_atDU1454.516356.920Details
BioGPS NCI60208747_s_atEKVX606.058356.920Details
BioGPS NCI60208747_s_atGM1331477.418356.920Details
BioGPS NCI60208747_s_atGM16001684.468356.920Details
BioGPS NCI60208747_s_atGM23136877.279356.920Details
BioGPS NCI60208747_s_atGM2345905.962356.920Details
BioGPS NCI60208747_s_atGM249340.159356.920Details
BioGPS NCI60208747_s_atGM971465.725356.920Details
BioGPS NCI60208747_s_atHCC29984.497356.920Details
BioGPS NCI60208747_s_atHCT1164.846356.920Details
BioGPS NCI60208747_s_atHCT154.469356.920Details
BioGPS NCI60208747_s_atHEK 293 T-rex4.867356.920Details
BioGPS NCI60208747_s_atHEK 293T4.735356.920Details
BioGPS NCI60208747_s_atHEK2934.722356.920Details
BioGPS NCI60208747_s_atHELA685.112356.920Details
BioGPS NCI60208747_s_atHEPG2160.432356.920Details
BioGPS NCI60208747_s_atHL605.000356.920Details
BioGPS NCI60208747_s_atHOP626.096356.920Details
BioGPS NCI60208747_s_atHOP921541.421356.920Details
BioGPS NCI60208747_s_atHS578T417.322356.920Details
BioGPS NCI60208747_s_atHSG537.043356.920Details
BioGPS NCI60208747_s_atHT10804.614356.920Details
BioGPS NCI60208747_s_atHT295.042356.920Details
BioGPS NCI60208747_s_atIGROV14.829356.920Details
BioGPS NCI60208747_s_atIOSE80381.189356.920Details
BioGPS NCI60208747_s_atJURKAT4.855356.920Details
BioGPS NCI60208747_s_atK5625.018356.920Details
BioGPS NCI60208747_s_atKM124.923356.920Details
BioGPS NCI60208747_s_atLN18540.787356.920Details
BioGPS NCI60208747_s_atLNCAP4.735356.920Details
BioGPS NCI60208747_s_atLOX IMVI4.720356.920Details
BioGPS NCI60208747_s_atM144.691356.920Details
BioGPS NCI60208747_s_atMALME 3M5.040356.920Details
BioGPS NCI60208747_s_atMCF74.526356.920Details
BioGPS NCI60208747_s_atMD MB2314.811356.920Details
BioGPS NCI60208747_s_atMDA MB4355.107356.920Details
BioGPS NCI60208747_s_atMOLT44.930356.920Details
BioGPS NCI60208747_s_atNCI 460491.695356.920Details
BioGPS NCI60208747_s_atNCI H2262200.641356.920Details
BioGPS NCI60208747_s_atNCI H23908.670356.920Details
BioGPS NCI60208747_s_atNCI H322M4.757356.920Details
BioGPS NCI60208747_s_atNCVADR RES54.419356.920Details
BioGPS NCI60208747_s_atOVCAR34.988356.920Details
BioGPS NCI60208747_s_atOVCAR44.719356.920Details
BioGPS NCI60208747_s_atOVCAR54.594356.920Details
BioGPS NCI60208747_s_atOVCAR856.139356.920Details
BioGPS NCI60208747_s_atPANC14.800356.920Details
BioGPS NCI60208747_s_atRL74.867356.920Details
BioGPS NCI60208747_s_atRPMI 82264.860356.920Details
BioGPS NCI60208747_s_atRS118465.108356.920Details
BioGPS NCI60208747_s_atRXF3931277.590356.920Details
BioGPS NCI60208747_s_atSAOS24.772356.920Details
BioGPS NCI60208747_s_atSF26845.152356.920Details
BioGPS NCI60208747_s_atSF295484.219356.920Details
BioGPS NCI60208747_s_atSF539371.413356.920Details
BioGPS NCI60208747_s_atSHSYSY+RA4.643356.920Details
BioGPS NCI60208747_s_atSHSYSY-RA4.603356.920Details
BioGPS NCI60208747_s_atSKMEL24.697356.920Details
BioGPS NCI60208747_s_atSKMEL284.815356.920Details
BioGPS NCI60208747_s_atSKMEL510.042356.920Details
BioGPS NCI60208747_s_atSKOV35.098356.920Details
BioGPS NCI60208747_s_atSN12C5.016356.920Details
BioGPS NCI60208747_s_atSNB194.566356.920Details
BioGPS NCI60208747_s_atSNB751993.978356.920Details
BioGPS NCI60208747_s_atSR4.800356.920Details
BioGPS NCI60208747_s_atSW6204.833356.920Details
BioGPS NCI60208747_s_atT244.826356.920Details
BioGPS NCI60208747_s_atT3M469.975356.920Details
BioGPS NCI60208747_s_atTK104.839356.920Details
BioGPS NCI60208747_s_atU118906.362356.920Details
BioGPS NCI60208747_s_atU138123.027356.920Details
BioGPS NCI60208747_s_atU20S4.660356.920Details
BioGPS NCI60208747_s_atU2514.830356.920Details
BioGPS NCI60208747_s_atU87396.510356.920Details
BioGPS NCI60208747_s_atUACC257676.865356.920Details
BioGPS NCI60208747_s_atUACC6230.040356.920Details
BioGPS NCI60208747_s_atUO314.760356.920Details
BioGPS NCI60208747_s_atZR75_14.928356.920Details
BioGPS NCI60208747_s_atastrocytes4.684356.920Details
BioGPS NCI60208747_s_athuh-722.732356.920Details