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Gene ID: 714 | C1QC Antibody Resource


C1QC Antibody Resource
Gene Full Name: 
complement component 1, q subcomponent, C chain
Uniprot: 
P02747
Protein Name: 
complement C1q subcomponent subunit C
Nucleotide: 
XM_005245983
Alias: 
C1QG;C1Q-C;
Ensembl: 
ENSG00000159189
Location: 
1p36.11
HPRD: 
00395
NCBI Gene: 
714
MIM: 
120575

Summary: 
This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Function: 
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Subcellular location: 
Secreted.
PTM: 
Disulfide bond;
Disease: 
Complement component C1q deficiency (C1QD) [MIM:613652]: A disorder caused by impaired activation of the complement classical pathway. It generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Monoclonal Antibody OASA00995 C1QC Antibody (OASA00995) Human IHC-AFF, ELISA, WB 0.1mg $925 Details
Polyclonal Antibody OASA09135 C1QC Antibody (OASA09135) Human ID 1ml $415 Details
Polyclonal Antibody OASA09136 C1QC Antibody (OASA09136) Human IHC-AFF 1ml $485 Details
Polyclonal Antibody OASA09137 C1QC Antibody (OASA09137) Human ELISA 1ml $370 Details
Polyclonal Antibody ARP60065_P050 C1QC Antibody (ARP60065_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB08173 C1QC antibody - center region (OAAB08173) Human WB, IHC, FC, IF 400ul $289 Details
Polyclonal Antibody OAAF03517 C1QC Antibody (OAAF03517) Polyclonal Human, Mouse, Rat WB, IHC 100 ug $229 Details

Show all C1QC antibodies


Product Images
C1QC antibody - center region (OAAB08173) in HL-60 cells using Flow Cytometry

Sample Type: HL-60

C1QC antibody - center region (OAAB08173) in HL-60 cells using Western Blot

Sample Type: HL-60

C1QC antibody - center region (OAAB08173) in Human Rectum cells using Immunohistochemistry

Sample Type: Human Rectum

C1QC antibody - center region (OAAB08173) in WiDr cells using Immunofluorescence

Sample Type: WiDr

C1QC Antibody (OAAF03517) in Human lung carcinoma cells using Immunohistochemistry

Sample Type: Human lung carcinoma

C1QC Antibody (OAAF03517) in Rat lung cells using Western Blot

Sample Type: Rat lung


C1QC Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP60065 Bovine C1QC antibody; Bos taurus C1QC antibody Q1RMH5 92.0%
ARP60009 Bovine C1QC antibody; Bos taurus C1QC antibody Q1RMH5 83.0%
ARP60065 Cat C1QC antibody; Felis catus C1QC antibody M3VUY8 100.0%
ARP60065 Chimpanzee C1QC antibody; Pan troglodytes C1QC antibody H2PYA2 100.0%
ARP60065 Dog C1QC antibody; Canis familiaris C1QC antibody E2RJC2 100.0%
ARP60025 Dog C1QC antibody; Canis familiaris C1QC antibody E2RJC2 79.0%
ARP60065 European domestic ferret C1QC antibody; Mustela putorius furo C1QC antibody M3YWY7 100.0%
ARP60025 European domestic ferret C1QC antibody; Mustela putorius furo C1QC antibody M3YWY7 79.0%
ARP60065 Giant panda C1QC antibody; Ailuropoda melanoleuca C1QC antibody G1M895 100.0%
ARP60025 Giant panda C1QC antibody; Ailuropoda melanoleuca C1QC antibody G1M895 79.0%
ARP45674 Grass carp C1QC antibody; Ctenopharyngodon idella C1QC antibody H9CTG0 83.0%
ARP60009 Gray short-tailed opossum C1QC antibody; Monodelphis domestica C1QC antibody F7EAZ8 83.0%
ARP60065 Horse C1QC antibody; Equus caballus C1QC antibody F7DBT2 100.0%
ARP60025 Horse C1QC antibody; Equus caballus C1QC antibody F7DBT2 79.0%
ARP60065 Human C1QC antibody; Homo sapiens C1QC antibody P02747 100.0%
ARP60065 Mouse C1QC antibody; Mus musculus C1QC antibody Q02105 92.0%
ARP60025 Mouse C1QC antibody; Mus musculus C1QC antibody Q02105 79.0%
ARP60065 Pig C1QC antibody; Sus scrofa C1QC antibody F1STZ3 100.0%
ARP60009 Pig C1QC antibody; Sus scrofa C1QC antibody F1STZ3 83.0%
ARP65742 Pig C1QC antibody; Sus scrofa C1QC antibody F1STZ3 79.0%
ARP68020 Pig C1QC antibody; Sus scrofa C1QC antibody F1STZ3 79.0%
ARP60065 Rabbit C1QC antibody; Oryctolagus cuniculus C1QC antibody G1T8T3 92.0%
ARP60025 Rabbit C1QC antibody; Oryctolagus cuniculus C1QC antibody G1T8T3 79.0%
ARP60065 Rat C1QC antibody; Rattus norvegicus C1QC antibody P31722 100.0%
ARP60025 Rat C1QC antibody; Rattus norvegicus C1QC antibody P31722 79.0%
ARP44296 Rhesus macaque C1QC antibody; Macaca mulatta C1QC antibody F7HEK8 100.0%
ARP44297 Rhesus macaque C1QC antibody; Macaca mulatta C1QC antibody F7HEK8 100.0%
ARP60065 Rhesus macaque C1QC antibody; Macaca mulatta C1QC antibody F7HEL0 93.0%
ARP60025 Rhesus macaque C1QC antibody; Macaca mulatta C1QC antibody F7HEL0 79.0%
ARP60065 Small-eared galago C1QC antibody; Otolemur garnettii C1QC antibody H0X5W0 100.0%
ARP60065 Sumatran orangutan C1QC antibody; Pongo abelii C1QC antibody H2N8N6 100.0%
ARP60065 white-tailed deer C1QC antibody; Odocoileus virginianus C1QC antibody C0LXP2 92.0%
ARP60065 white-tailed deer C1QC antibody; Odocoileus virginianus C1QC antibody C0LXP4 92.0%
ARP60065 white-tailed deer C1QC antibody; Odocoileus virginianus C1QC antibody C0LXP5 92.0%
ARP60065 white-tailed deer C1QC antibody; Odocoileus virginianus C1QC antibody C0LXP6 92.0%
ARP60065 white-tailed deer C1QC antibody; Odocoileus virginianus C1QC antibody C0LXR5 85.0%
ARP60065 white-tailed deer C1QC antibody; Odocoileus virginianus C1QC antibody C0LXR7 85.0%
ARP60065 white-tailed deer C1QC antibody; Odocoileus virginianus C1QC antibody C0LXS0 85.0%
ARP60065 White-tufted-ear marmoset C1QC antibody; Callithrix jacchus C1QC antibody F7IS76 93.0%
ARP60065 White-tufted-ear marmoset C1QC antibody; Callithrix jacchus C1QC antibody F7ISA6 93.0%
ARP60025 White-tufted-ear marmoset C1QC antibody; Callithrix jacchus C1QC antibody F7IS76 79.0%
ARP60025 White-tufted-ear marmoset C1QC antibody; Callithrix jacchus C1QC antibody F7ISA6 79.0%
ARP45674 Zebrafish C1QC antibody; Danio rerio C1QC antibody D3U1E2 83.0%
ARP45674 Zebrafish C1QC antibody; Danio rerio C1QC antibody F1RAV1 83.0%
ARP45674 Zebrafish C1QC antibody; Danio rerio C1QC antibody Q5XJ71 83.0%

Tissue & Cell Line Gene Expression Data