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Gene ID: 713 | C1QB Antibody Resource


C1QB Antibody Resource
Gene Full Name: 
complement component 1, q subcomponent, B chain
Uniprot: 
P02746
Protein Name: 
complement C1q subcomponent subunit B
Nucleotide: 
NM_000491
Alias: 
Ensembl: 
ENSG00000173369
Location: 
1p36.12
HPRD: 
00394
NCBI Gene: 
713
MIM: 
120570

Summary: 
This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q [provided by RefSeq, Jul 2008]
Function: 
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Subcellular location: 
Secreted.
PTM: 
Disulfide bond;
Disease: 
Complement component C1q deficiency (C1QD) [MIM:613652]: A disorder caused by impaired activation of the complement classical pathway. It generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP44297_P050 C1QB antibody - C-terminal region (ARP44297_P050) Polyclonal Dog, Human IHC, WB 50ug $289 Details
Polyclonal Antibody ARP44296_P050 C1QB antibody - middle region (ARP44296_P050) Polyclonal Bovine, Dog, Guinea pig, Human, Mouse, Pig, Rat WB 50ug $289 Details
Polyclonal Antibody OAAB05489 C1QB antibody - N-terminal region (OAAB05489) Human WB, FC, ELISA 400ul $289 Details
Polyclonal Antibody OAAF03516 C1QB Antibody (OAAF03516) Polyclonal Human WB, IF, ELISA 100 ug $289 Details

Show all C1QB antibodies


Product Images
C1QB antibody - middle region (ARP44296_P050) in Human Stomach cells using Western Blot

Sample Type: Human Stomach

C1QB antibody - C-terminal region (ARP44297_P050) in Human Jurkat cells using Western Blot

Sample Type: Human Jurkat

C1QB antibody - C-terminal region (ARP44297_P050) in Human Muscle cells using Immunohistochemistry

Sample Type: Human Muscle

C1QB antibody - N-terminal region (OAAB05489) in C1QB cells using Western Blot

Sample Type: C1QB

C1QB antibody - N-terminal region (OAAB05489) in Jurkat cells using Western Blot

Sample Type: Jurkat

C1QB antibody - N-terminal region (OAAB05489) in Jurkat cells using Flow Cytometry

Sample Type: Jurkat

C1QB Antibody (OAAF03516) in Jurkat cells using Western Blot

Sample Type: Jurkat


C1QB Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP44296 Bovine C1QB antibody; Bos taurus C1QB antibody Q2KIV9 100.0%
ARP44296 Cat C1QB antibody; Felis catus C1QB antibody M3VUY9 100.0%
ARP44297 Cat C1QB antibody; Felis catus C1QB antibody M3VUY9 100.0%
ARP44296 Chimpanzee C1QB antibody; Pan troglodytes C1QB antibody H2QZN9 100.0%
ARP44297 Chimpanzee C1QB antibody; Pan troglodytes C1QB antibody H2QZN9 86.0%
ARP44296 Chinese softshell turtle C1QB antibody; Pelodiscus sinensis C1QB antibody K7F218 79.0%
ARP44296 Dog C1QB antibody; Canis familiaris C1QB antibody J9P1G2 100.0%
ARP44297 Dog C1QB antibody; Canis familiaris C1QB antibody J9P1G2 92.0%
ARP44296 Domestic duck C1QB antibody; Anas platyrhynchos C1QB antibody U3I5B4 79.0%
ARP44296 Horse C1QB antibody; Equus caballus C1QB antibody F7BUV8 86.0%
ARP44297 Horse C1QB antibody; Equus caballus C1QB antibody F7BUV8 82.0%
ARP44296 Human C1QB antibody; Homo sapiens C1QB antibody D6R934 100.0%
ARP44297 Human C1QB antibody; Homo sapiens C1QB antibody D6R934 100.0%
ARP44296 Human C1QB antibody; Homo sapiens C1QB antibody D6RA08 100.0%
ARP44297 Human C1QB antibody; Homo sapiens C1QB antibody D6RA08 100.0%
ARP44296 Human C1QB antibody; Homo sapiens C1QB antibody D6RGJ1 100.0%
ARP44296 Human C1QB antibody; Homo sapiens C1QB antibody P02746 100.0%
ARP44297 Human C1QB antibody; Homo sapiens C1QB antibody P02746 100.0%
ARP44296 Little brown bat C1QB antibody; Myotis lucifugus C1QB antibody G1NZH8 93.0%
ARP60064 Little brown bat C1QB antibody; Myotis lucifugus C1QB antibody G1NZH8 86.0%
ARP44297 Little brown bat C1QB antibody; Myotis lucifugus C1QB antibody G1NZH8 83.0%
ARP44296 Mouse C1QB antibody; Mus musculus C1QB antibody P14106 79.0%
ARP44296 Mouse C1QB antibody; Mus musculus C1QB antibody Q3U6I5 79.0%
ARP44296 Mouse C1QB antibody; Mus musculus C1QB antibody Q3US82 79.0%
ARP44296 Pig C1QB antibody; Sus scrofa C1QB antibody F1STZ1 100.0%
ARP44296 Rat C1QB antibody; Rattus norvegicus C1QB antibody P31721 92.0%
ARP44296 Rat C1QB antibody; Rattus norvegicus C1QB antibody G3V7N9 86.0%
ARP44296 Rhesus macaque C1QB antibody; Macaca mulatta C1QB antibody G7MHG1 100.0%
ARP44297 Rhesus macaque C1QB antibody; Macaca mulatta C1QB antibody G7MHG1 100.0%
ARP44296 Small-eared galago C1QB antibody; Otolemur garnettii C1QB antibody H0X5V6 93.0%
ARP44297 Small-eared galago C1QB antibody; Otolemur garnettii C1QB antibody H0X5V6 86.0%
ARP66007 Small-eared galago C1QB antibody; Otolemur garnettii C1QB antibody H0X5V6 86.0%
ARP44296 Sumatran orangutan C1QB antibody; Pongo abelii C1QB antibody H2N8N5 100.0%
ARP44297 Sumatran orangutan C1QB antibody; Pongo abelii C1QB antibody H2N8N5 100.0%
ARP44296 Thirteen-lined ground squirrel C1QB antibody; Spermophilus tridecemlineatus C1QB antibody I3MWG3 100.0%
ARP44297 Thirteen-lined ground squirrel C1QB antibody; Spermophilus tridecemlineatus C1QB antibody I3MWG3 93.0%
ARP60025 Thirteen-lined ground squirrel C1QB antibody; Spermophilus tridecemlineatus C1QB antibody I3MWG3 79.0%
ARP44296 white-tailed deer C1QB antibody; Odocoileus virginianus C1QB antibody C0LXI9 93.0%
ARP44296 white-tailed deer C1QB antibody; Odocoileus virginianus C1QB antibody C0LXJ3 93.0%
ARP44296 white-tailed deer C1QB antibody; Odocoileus virginianus C1QB antibody C0LXJ7 93.0%
ARP44296 white-tailed deer C1QB antibody; Odocoileus virginianus C1QB antibody C0LXL1 93.0%
ARP44297 white-tailed deer C1QB antibody; Odocoileus virginianus C1QB antibody C0LXI9 79.0%
ARP44297 white-tailed deer C1QB antibody; Odocoileus virginianus C1QB antibody C0LXJ3 79.0%
ARP44297 white-tailed deer C1QB antibody; Odocoileus virginianus C1QB antibody C0LXJ7 79.0%
ARP44297 white-tailed deer C1QB antibody; Odocoileus virginianus C1QB antibody C0LXL1 79.0%
ARP44296 White-tufted-ear marmoset C1QB antibody; Callithrix jacchus C1QB antibody F7HN79 100.0%
ARP44297 White-tufted-ear marmoset C1QB antibody; Callithrix jacchus C1QB antibody F7HN79 100.0%
ARP44296 White-tufted-ear marmoset C1QB antibody; Callithrix jacchus C1QB antibody F7HTS9 100.0%
ARP44297 White-tufted-ear marmoset C1QB antibody; Callithrix jacchus C1QB antibody F7HTS9 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas202953_at721_B_lymphoblasts9.95088.450Details
BioGPS Gene Atlas202953_atAdipocyte15.45088.450Details
BioGPS Gene Atlas202953_atAdrenalCortex34.05088.450Details
BioGPS Gene Atlas202953_atAdrenalgland90.20088.450Details
BioGPS Gene Atlas202953_atAmygdala37.10088.450Details
BioGPS Gene Atlas202953_atAppendix18.05088.450Details
BioGPS Gene Atlas202953_atAtrioventricularNode14.95088.450Details
BioGPS Gene Atlas202953_atBDCA4+_DentriticCells21.55088.450Details
BioGPS Gene Atlas202953_atBonemarrow20.25088.450Details
BioGPS Gene Atlas202953_atBronchialEpithelialCells15.30088.450Details
BioGPS Gene Atlas202953_atCD105+_Endothelial370.35088.450Details
BioGPS Gene Atlas202953_atCD14+_Monocytes17.30088.450Details
BioGPS Gene Atlas202953_atCD19+_BCells(neg._sel.)10.85088.450Details
BioGPS Gene Atlas202953_atCD33+_Myeloid19.20088.450Details
BioGPS Gene Atlas202953_atCD34+16.75088.450Details
BioGPS Gene Atlas202953_atCD4+_Tcells15.90088.450Details
BioGPS Gene Atlas202953_atCD56+_NKCells14.90088.450Details
BioGPS Gene Atlas202953_atCD71+_EarlyErythroid14.85088.450Details
BioGPS Gene Atlas202953_atCD8+_Tcells12.70088.450Details
BioGPS Gene Atlas202953_atCardiacMyocytes24.75088.450Details
BioGPS Gene Atlas202953_atCaudatenucleus34.65088.450Details
BioGPS Gene Atlas202953_atCerebellum13.40088.450Details
BioGPS Gene Atlas202953_atCerebellumPeduncles19.55088.450Details
BioGPS Gene Atlas202953_atCiliaryGanglion14.30088.450Details
BioGPS Gene Atlas202953_atCingulateCortex16.05088.450Details
BioGPS Gene Atlas202953_atColorectaladenocarcinoma15.95088.450Details
BioGPS Gene Atlas202953_atDorsalRootGanglion27.10088.450Details
BioGPS Gene Atlas202953_atFetalThyroid16.85088.450Details
BioGPS Gene Atlas202953_atFetalbrain16.05088.450Details
BioGPS Gene Atlas202953_atFetalliver28.70088.450Details
BioGPS Gene Atlas202953_atFetallung68.85088.450Details
BioGPS Gene Atlas202953_atGlobusPallidus12.40088.450Details
BioGPS Gene Atlas202953_atHeart1995.00088.450Details
BioGPS Gene Atlas202953_atHypothalamus59.50088.450Details
BioGPS Gene Atlas202953_atKidney13.95088.450Details
BioGPS Gene Atlas202953_atLeukemia_chronicMyelogenousK-56214.20088.450Details
BioGPS Gene Atlas202953_atLeukemia_promyelocytic-HL-607.70088.450Details
BioGPS Gene Atlas202953_atLeukemialymphoblastic(MOLT-4)12.00088.450Details
BioGPS Gene Atlas202953_atLiver219.90088.450Details
BioGPS Gene Atlas202953_atLung1813.20088.450Details
BioGPS Gene Atlas202953_atLymphnode247.85088.450Details
BioGPS Gene Atlas202953_atLymphoma_burkitts(Daudi)20.90088.450Details
BioGPS Gene Atlas202953_atLymphoma_burkitts(Raji)20.40088.450Details
BioGPS Gene Atlas202953_atMedullaOblongata14.60088.450Details
BioGPS Gene Atlas202953_atOccipitalLobe15.60088.450Details
BioGPS Gene Atlas202953_atOlfactoryBulb112.50088.450Details
BioGPS Gene Atlas202953_atOvary165.25088.450Details
BioGPS Gene Atlas202953_atPancreas17.25088.450Details
BioGPS Gene Atlas202953_atPancreaticIslet116.00088.450Details
BioGPS Gene Atlas202953_atParietalLobe18.25088.450Details
BioGPS Gene Atlas202953_atPituitary53.25088.450Details
BioGPS Gene Atlas202953_atPlacenta381.65088.450Details
BioGPS Gene Atlas202953_atPons16.30088.450Details
BioGPS Gene Atlas202953_atPrefrontalCortex31.20088.450Details
BioGPS Gene Atlas202953_atProstate31.90088.450Details
BioGPS Gene Atlas202953_atSalivarygland17.80088.450Details
BioGPS Gene Atlas202953_atSkeletalMuscle20.05088.450Details
BioGPS Gene Atlas202953_atSkin13.60088.450Details
BioGPS Gene Atlas202953_atSmoothMuscle18.10088.450Details
BioGPS Gene Atlas202953_atSpinalcord77.75088.450Details
BioGPS Gene Atlas202953_atSubthalamicNucleus15.35088.450Details
BioGPS Gene Atlas202953_atSuperiorCervicalGanglion25.95088.450Details
BioGPS Gene Atlas202953_atTemporalLobe35.70088.450Details
BioGPS Gene Atlas202953_atTestis13.85088.450Details
BioGPS Gene Atlas202953_atTestisGermCell12.60088.450Details
BioGPS Gene Atlas202953_atTestisIntersitial13.55088.450Details
BioGPS Gene Atlas202953_atTestisLeydigCell19.90088.450Details
BioGPS Gene Atlas202953_atTestisSeminiferousTubule13.95088.450Details
BioGPS Gene Atlas202953_atThalamus22.90088.450Details
BioGPS Gene Atlas202953_atThymus113.75088.450Details
BioGPS Gene Atlas202953_atThyroid21.90088.450Details
BioGPS Gene Atlas202953_atTongue24.90088.450Details
BioGPS Gene Atlas202953_atTonsil34.85088.450Details
BioGPS Gene Atlas202953_atTrachea18.40088.450Details
BioGPS Gene Atlas202953_atTrigeminalGanglion20.70088.450Details
BioGPS Gene Atlas202953_atUterus28.10088.450Details
BioGPS Gene Atlas202953_atUterusCorpus20.95088.450Details
BioGPS Gene Atlas202953_atWholeBlood14.15088.450Details
BioGPS Gene Atlas202953_atWholebrain41.35088.450Details
BioGPS Gene Atlas202953_atcolon17.05088.450Details
BioGPS Gene Atlas202953_atpineal_day24.48088.450Details
BioGPS Gene Atlas202953_atpineal_night22.72088.450Details
BioGPS Gene Atlas202953_atretina181.92588.450Details
BioGPS Gene Atlas202953_atsmall_intestine148.05088.450Details
BioGPS NCI60202953_at7867.9967.660Details
BioGPS NCI60202953_atA1726.9257.660Details
BioGPS NCI60202953_atA2047.5107.660Details
BioGPS NCI60202953_atA3617.7107.660Details
BioGPS NCI60202953_atA4987.5657.660Details
BioGPS NCI60202953_atA5497.6607.660Details
BioGPS NCI60202953_atACC38.1937.660Details
BioGPS NCI60202953_atACHN6.8297.660Details
BioGPS NCI60202953_atALVA317.8257.660Details
BioGPS NCI60202953_atCAKI18.3057.660Details
BioGPS NCI60202953_atCCRT CEM10.8427.660Details
BioGPS NCI60202953_atCOLO2057.5557.660Details
BioGPS NCI60202953_atDLD17.4767.660Details
BioGPS NCI60202953_atDU1457.1317.660Details
BioGPS NCI60202953_atEKVX7.1097.660Details
BioGPS NCI60202953_atGM1337.7347.660Details
BioGPS NCI60202953_atGM16008.1997.660Details
BioGPS NCI60202953_atGM23137.6707.660Details
BioGPS NCI60202953_atGM23457.5537.660Details
BioGPS NCI60202953_atGM24938.6167.660Details
BioGPS NCI60202953_atGM979.1617.660Details
BioGPS NCI60202953_atHCC29985.9377.660Details
BioGPS NCI60202953_atHCT1167.6097.660Details
BioGPS NCI60202953_atHCT157.1347.660Details
BioGPS NCI60202953_atHEK 293 T-rex8.1347.660Details
BioGPS NCI60202953_atHEK 293T7.4107.660Details
BioGPS NCI60202953_atHEK2937.5367.660Details
BioGPS NCI60202953_atHELA6.4707.660Details
BioGPS NCI60202953_atHEPG27.6117.660Details
BioGPS NCI60202953_atHL608.3987.660Details
BioGPS NCI60202953_atHOP627.5867.660Details
BioGPS NCI60202953_atHOP927.2267.660Details
BioGPS NCI60202953_atHS578T7.5077.660Details
BioGPS NCI60202953_atHSG7.0377.660Details
BioGPS NCI60202953_atHT10807.3837.660Details
BioGPS NCI60202953_atHT298.5647.660Details
BioGPS NCI60202953_atIGROV17.4117.660Details
BioGPS NCI60202953_atIOSE807.5227.660Details
BioGPS NCI60202953_atJURKAT7.5467.660Details
BioGPS NCI60202953_atK5628.9447.660Details
BioGPS NCI60202953_atKM128.1157.660Details
BioGPS NCI60202953_atLN186.9077.660Details
BioGPS NCI60202953_atLNCAP7.5877.660Details
BioGPS NCI60202953_atLOX IMVI7.5387.660Details
BioGPS NCI60202953_atM147.5017.660Details
BioGPS NCI60202953_atMALME 3M9.7337.660Details
BioGPS NCI60202953_atMCF77.2637.660Details
BioGPS NCI60202953_atMD MB2317.7417.660Details
BioGPS NCI60202953_atMDA MB4358.9227.660Details
BioGPS NCI60202953_atMOLT48.2967.660Details
BioGPS NCI60202953_atNCI 4607.8507.660Details
BioGPS NCI60202953_atNCI H2268.1337.660Details
BioGPS NCI60202953_atNCI H237.7157.660Details
BioGPS NCI60202953_atNCI H322M7.5837.660Details
BioGPS NCI60202953_atNCVADR RES6.7707.660Details
BioGPS NCI60202953_atOVCAR38.6947.660Details
BioGPS NCI60202953_atOVCAR47.5357.660Details
BioGPS NCI60202953_atOVCAR57.4607.660Details
BioGPS NCI60202953_atOVCAR86.9217.660Details
BioGPS NCI60202953_atPANC17.6357.660Details
BioGPS NCI60202953_atRL77.6647.660Details
BioGPS NCI60202953_atRPMI 82268.0497.660Details
BioGPS NCI60202953_atRS118468.4127.660Details
BioGPS NCI60202953_atRXF3937.5287.660Details
BioGPS NCI60202953_atSAOS27.6437.660Details
BioGPS NCI60202953_atSF2687.5607.660Details
BioGPS NCI60202953_atSF2957.4757.660Details
BioGPS NCI60202953_atSF5396.9387.660Details
BioGPS NCI60202953_atSHSYSY+RA7.0597.660Details
BioGPS NCI60202953_atSHSYSY-RA7.3727.660Details
BioGPS NCI60202953_atSKMEL27.5447.660Details
BioGPS NCI60202953_atSKMEL287.5847.660Details
BioGPS NCI60202953_atSKMEL57.3997.660Details
BioGPS NCI60202953_atSKOV38.0577.660Details
BioGPS NCI60202953_atSN12C7.4257.660Details
BioGPS NCI60202953_atSNB196.9647.660Details
BioGPS NCI60202953_atSNB757.5387.660Details
BioGPS NCI60202953_atSR7.9347.660Details
BioGPS NCI60202953_atSW6207.7927.660Details
BioGPS NCI60202953_atT247.8947.660Details
BioGPS NCI60202953_atT3M48.0847.660Details
BioGPS NCI60202953_atTK107.5227.660Details
BioGPS NCI60202953_atU1187.3257.660Details
BioGPS NCI60202953_atU1387.0837.660Details
BioGPS NCI60202953_atU20S7.3717.660Details
BioGPS NCI60202953_atU2517.4867.660Details
BioGPS NCI60202953_atU877.0977.660Details
BioGPS NCI60202953_atUACC2577.3037.660Details
BioGPS NCI60202953_atUACC627.6317.660Details
BioGPS NCI60202953_atUO317.2427.660Details
BioGPS NCI60202953_atZR75_18.1917.660Details
BioGPS NCI60202953_atastrocytes7.6247.660Details
BioGPS NCI60202953_athuh-78.0277.660Details