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Gene ID: 712 | C1QA Antibody Resource


C1QA Antibody Resource
Gene Full Name: 
complement component 1, q subcomponent, A chain
Uniprot: 
P02745
Protein Name: 
complement C1q subcomponent subunit A
Nucleotide: 
NM_015991
Alias: 
Ensembl: 
ENSG00000173372
Location: 
1p36.12
HPRD: 
00393
NCBI Gene: 
712
MIM: 
120550

Summary: 
This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q. [provided by RefSeq, Jul 2008]
Function: 
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Subcellular location: 
Secreted.
PTM: 
Disulfide bond;
Disease: 
Complement component C1q deficiency (C1QD) [MIM:613652]: A disorder caused by impaired activation of the complement classical pathway. It generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP60064_P050 C1QA antibody - N-terminal region (ARP60064_P050) Polyclonal Bovine, Human, Mouse, Pig, Rat WB 50ug $289 Details
Monoclonal Antibody OASA00996 C1QA Antibody (OASA00996) Human IHC-AFF, ELISA, FC 0.1ml $515 Details
Others OOSA09709 NATIVE HUMAN C1q Antigen (1mg) Human 1mg $670 Details
Polyclonal Antibody OAAB04314 C1QA antibody - C-terminal region (OAAB04314) Human WB, FC, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP60063_P050 C1QA Antibody (ARP60063_P050) Polyclonal Human, Mouse, Rat Not tested 50 ug $125 Details

Show all C1QA antibodies


Product Images
C1QA antibody - N-terminal region (ARP60064_P050) in Human HeLa cells using Western Blot

Sample Type: Human HeLa

C1QA antibody - C-terminal region (OAAB04314) in human brain carcinoma cells using Immunohistochemistry

Sample Type: human brain carcinoma

C1QA antibody - C-terminal region (OAAB04314) in Jurkat cells using Western Blot

Sample Type: Jurkat

C1QA antibody - C-terminal region (OAAB04314) in MCF-7 cells using Flow Cytometry

Sample Type: MCF-7


C1QA Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP60064 Bovine C1QA antibody; Bos taurus C1QA antibody Q5E9E3 100.0%
ARP60064 Cat C1QA antibody; Felis catus C1QA antibody M3WS63 93.0%
ARP60063 Chimpanzee C1QA antibody; Pan troglodytes C1QA antibody H2RE24 100.0%
ARP60064 Chimpanzee C1QA antibody; Pan troglodytes C1QA antibody H2RE24 100.0%
ARP60064 Chinese softshell turtle C1QA antibody; Pelodiscus sinensis C1QA antibody K7FM68 79.0%
ARP60064 Dog C1QA antibody; Canis familiaris C1QA antibody J9P4B4 86.0%
ARP60063 Dog C1QA antibody; Canis familiaris C1QA antibody J9P4B4 79.0%
ARP60064 Giant panda C1QA antibody; Ailuropoda melanoleuca C1QA antibody G1M893 93.0%
ARP60064 Horse C1QA antibody; Equus caballus C1QA antibody F6TIN6 86.0%
ARP60063 Human C1QA antibody; Homo sapiens C1QA antibody P02745 100.0%
ARP60064 Human C1QA antibody; Homo sapiens C1QA antibody P02745 100.0%
ARP60064 Mouse C1QA antibody; Mus musculus C1QA antibody P98086 86.0%
ARP60064 Mouse C1QA antibody; Mus musculus C1QA antibody Q3TXB1 86.0%
ARP60064 Mouse C1QA antibody; Mus musculus C1QA antibody Q3UBX7 86.0%
ARP60063 Mouse C1QA antibody; Mus musculus C1QA antibody P98086 79.0%
ARP60063 Mouse C1QA antibody; Mus musculus C1QA antibody Q3TXB1 79.0%
ARP60063 Mouse C1QA antibody; Mus musculus C1QA antibody Q3UBX7 79.0%
ARP60064 Pig C1QA antibody; Sus scrofa C1QA antibody F1STZ4 86.0%
ARP60064 Pig C1QA antibody; Sus scrofa C1QA antibody Q69DL0 86.0%
ARP60064 Rabbit C1QA antibody; Oryctolagus cuniculus C1QA antibody U3KMB5 85.0%
ARP60064 Rat C1QA antibody; Rattus norvegicus C1QA antibody P31720 86.0%
ARP60063 Rat C1QA antibody; Rattus norvegicus C1QA antibody P31720 79.0%
ARP60064 Rhesus macaque C1QA antibody; Macaca mulatta C1QA antibody F7HEL4 93.0%
ARP60063 Rhesus macaque C1QA antibody; Macaca mulatta C1QA antibody F7HEL4 86.0%
ARP60064 Small-eared galago C1QA antibody; Otolemur garnettii C1QA antibody H0XYC7 86.0%
ARP60063 Small-eared galago C1QA antibody; Otolemur garnettii C1QA antibody H0XYC7 79.0%
ARP60064 white-tailed deer C1QA antibody; Odocoileus virginianus C1QA antibody C0LXV2 100.0%
ARP60064 white-tailed deer C1QA antibody; Odocoileus virginianus C1QA antibody C0LXV6 100.0%
ARP60064 white-tailed deer C1QA antibody; Odocoileus virginianus C1QA antibody C0LXV5 91.0%
ARP60064 White-tufted-ear marmoset C1QA antibody; Callithrix jacchus C1QA antibody U3C8K1 86.0%
ARP60063 White-tufted-ear marmoset C1QA antibody; Callithrix jacchus C1QA antibody U3C8K1 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas218232_at721_B_lymphoblasts15.90083.810Details
BioGPS Gene Atlas218232_atAdipocyte14.95083.810Details
BioGPS Gene Atlas218232_atAdrenalCortex24.45083.810Details
BioGPS Gene Atlas218232_atAdrenalgland217.20083.810Details
BioGPS Gene Atlas218232_atAmygdala21.50083.810Details
BioGPS Gene Atlas218232_atAppendix21.75083.810Details
BioGPS Gene Atlas218232_atAtrioventricularNode14.40083.810Details
BioGPS Gene Atlas218232_atBDCA4+_DentriticCells24.35083.810Details
BioGPS Gene Atlas218232_atBonemarrow86.05083.810Details
BioGPS Gene Atlas218232_atBronchialEpithelialCells14.95083.810Details
BioGPS Gene Atlas218232_atCD105+_Endothelial237.60083.810Details
BioGPS Gene Atlas218232_atCD14+_Monocytes26.30083.810Details
BioGPS Gene Atlas218232_atCD19+_BCells(neg._sel.)9.00083.810Details
BioGPS Gene Atlas218232_atCD33+_Myeloid19.70083.810Details
BioGPS Gene Atlas218232_atCD34+12.75083.810Details
BioGPS Gene Atlas218232_atCD4+_Tcells13.20083.810Details
BioGPS Gene Atlas218232_atCD56+_NKCells15.80083.810Details
BioGPS Gene Atlas218232_atCD71+_EarlyErythroid12.55083.810Details
BioGPS Gene Atlas218232_atCD8+_Tcells6.25083.810Details
BioGPS Gene Atlas218232_atCardiacMyocytes21.25083.810Details
BioGPS Gene Atlas218232_atCaudatenucleus21.45083.810Details
BioGPS Gene Atlas218232_atCerebellum15.90083.810Details
BioGPS Gene Atlas218232_atCerebellumPeduncles20.90083.810Details
BioGPS Gene Atlas218232_atCiliaryGanglion18.70083.810Details
BioGPS Gene Atlas218232_atCingulateCortex18.75083.810Details
BioGPS Gene Atlas218232_atColorectaladenocarcinoma16.60083.810Details
BioGPS Gene Atlas218232_atDorsalRootGanglion67.95083.810Details
BioGPS Gene Atlas218232_atFetalThyroid26.25083.810Details
BioGPS Gene Atlas218232_atFetalbrain16.85083.810Details
BioGPS Gene Atlas218232_atFetalliver60.90083.810Details
BioGPS Gene Atlas218232_atFetallung118.65083.810Details
BioGPS Gene Atlas218232_atGlobusPallidus13.40083.810Details
BioGPS Gene Atlas218232_atHeart1311.40083.810Details
BioGPS Gene Atlas218232_atHypothalamus22.15083.810Details
BioGPS Gene Atlas218232_atKidney17.20083.810Details
BioGPS Gene Atlas218232_atLeukemia_chronicMyelogenousK-56213.85083.810Details
BioGPS Gene Atlas218232_atLeukemia_promyelocytic-HL-6014.95083.810Details
BioGPS Gene Atlas218232_atLeukemialymphoblastic(MOLT-4)12.35083.810Details
BioGPS Gene Atlas218232_atLiver267.50083.810Details
BioGPS Gene Atlas218232_atLung1182.85083.810Details
BioGPS Gene Atlas218232_atLymphnode238.65083.810Details
BioGPS Gene Atlas218232_atLymphoma_burkitts(Daudi)22.70083.810Details
BioGPS Gene Atlas218232_atLymphoma_burkitts(Raji)22.20083.810Details
BioGPS Gene Atlas218232_atMedullaOblongata14.55083.810Details
BioGPS Gene Atlas218232_atOccipitalLobe15.40083.810Details
BioGPS Gene Atlas218232_atOlfactoryBulb93.95083.810Details
BioGPS Gene Atlas218232_atOvary211.50083.810Details
BioGPS Gene Atlas218232_atPancreas14.10083.810Details
BioGPS Gene Atlas218232_atPancreaticIslet33.95083.810Details
BioGPS Gene Atlas218232_atParietalLobe16.60083.810Details
BioGPS Gene Atlas218232_atPituitary67.65083.810Details
BioGPS Gene Atlas218232_atPlacenta572.80083.810Details
BioGPS Gene Atlas218232_atPons19.05083.810Details
BioGPS Gene Atlas218232_atPrefrontalCortex61.90083.810Details
BioGPS Gene Atlas218232_atProstate27.80083.810Details
BioGPS Gene Atlas218232_atSalivarygland15.90083.810Details
BioGPS Gene Atlas218232_atSkeletalMuscle21.15083.810Details
BioGPS Gene Atlas218232_atSkin16.05083.810Details
BioGPS Gene Atlas218232_atSmoothMuscle17.25083.810Details
BioGPS Gene Atlas218232_atSpinalcord96.10083.810Details
BioGPS Gene Atlas218232_atSubthalamicNucleus17.65083.810Details
BioGPS Gene Atlas218232_atSuperiorCervicalGanglion19.50083.810Details
BioGPS Gene Atlas218232_atTemporalLobe30.50083.810Details
BioGPS Gene Atlas218232_atTestis16.85083.810Details
BioGPS Gene Atlas218232_atTestisGermCell14.10083.810Details
BioGPS Gene Atlas218232_atTestisIntersitial9.25083.810Details
BioGPS Gene Atlas218232_atTestisLeydigCell17.80083.810Details
BioGPS Gene Atlas218232_atTestisSeminiferousTubule15.75083.810Details
BioGPS Gene Atlas218232_atThalamus42.75083.810Details
BioGPS Gene Atlas218232_atThymus140.80083.810Details
BioGPS Gene Atlas218232_atThyroid55.80083.810Details
BioGPS Gene Atlas218232_atTongue21.20083.810Details
BioGPS Gene Atlas218232_atTonsil55.40083.810Details
BioGPS Gene Atlas218232_atTrachea40.80083.810Details
BioGPS Gene Atlas218232_atTrigeminalGanglion31.90083.810Details
BioGPS Gene Atlas218232_atUterus50.05083.810Details
BioGPS Gene Atlas218232_atUterusCorpus22.55083.810Details
BioGPS Gene Atlas218232_atWholeBlood15.65083.810Details
BioGPS Gene Atlas218232_atWholebrain32.95083.810Details
BioGPS Gene Atlas218232_atcolon90.15083.810Details
BioGPS Gene Atlas218232_atpineal_day34.02083.810Details
BioGPS Gene Atlas218232_atpineal_night28.68083.810Details
BioGPS Gene Atlas218232_atretina208.45083.810Details
BioGPS Gene Atlas218232_atsmall_intestine372.90083.810Details
BioGPS NCI60218232_at7864.8034.750Details
BioGPS NCI60218232_atA1724.3724.750Details
BioGPS NCI60218232_atA2044.5924.750Details
BioGPS NCI60218232_atA3614.6864.750Details
BioGPS NCI60218232_atA4984.6124.750Details
BioGPS NCI60218232_atA5494.6844.750Details
BioGPS NCI60218232_atACC34.9144.750Details
BioGPS NCI60218232_atACHN4.2664.750Details
BioGPS NCI60218232_atALVA315.1394.750Details
BioGPS NCI60218232_atCAKI14.8674.750Details
BioGPS NCI60218232_atCCRT CEM5.4504.750Details
BioGPS NCI60218232_atCOLO2054.6784.750Details
BioGPS NCI60218232_atDLD14.5024.750Details
BioGPS NCI60218232_atDU1454.3594.750Details
BioGPS NCI60218232_atEKVX4.4194.750Details
BioGPS NCI60218232_atGM1334.6834.750Details
BioGPS NCI60218232_atGM16004.8704.750Details
BioGPS NCI60218232_atGM23134.6664.750Details
BioGPS NCI60218232_atGM23454.5954.750Details
BioGPS NCI60218232_atGM24934.7794.750Details
BioGPS NCI60218232_atGM975.2884.750Details
BioGPS NCI60218232_atHCC29984.1334.750Details
BioGPS NCI60218232_atHCT1164.6104.750Details
BioGPS NCI60218232_atHCT154.3564.750Details
BioGPS NCI60218232_atHEK 293 T-rex4.7394.750Details
BioGPS NCI60218232_atHEK 293T4.6144.750Details
BioGPS NCI60218232_atHEK2934.5674.750Details
BioGPS NCI60218232_atHELA4.2994.750Details
BioGPS NCI60218232_atHEPG24.5934.750Details
BioGPS NCI60218232_atHL6011.1974.750Details
BioGPS NCI60218232_atHOP624.6214.750Details
BioGPS NCI60218232_atHOP924.4354.750Details
BioGPS NCI60218232_atHS578T4.5224.750Details
BioGPS NCI60218232_atHSG4.4114.750Details
BioGPS NCI60218232_atHT10804.4624.750Details
BioGPS NCI60218232_atHT295.0684.750Details
BioGPS NCI60218232_atIGROV14.5444.750Details
BioGPS NCI60218232_atIOSE804.5664.750Details
BioGPS NCI60218232_atJURKAT4.6034.750Details
BioGPS NCI60218232_atK5625.0384.750Details
BioGPS NCI60218232_atKM124.8354.750Details
BioGPS NCI60218232_atLN184.3534.750Details
BioGPS NCI60218232_atLNCAP4.5954.750Details
BioGPS NCI60218232_atLOX IMVI4.5994.750Details
BioGPS NCI60218232_atM144.5754.750Details
BioGPS NCI60218232_atMALME 3M4.9734.750Details
BioGPS NCI60218232_atMCF74.5214.750Details
BioGPS NCI60218232_atMD MB2314.6374.750Details
BioGPS NCI60218232_atMDA MB4355.0084.750Details
BioGPS NCI60218232_atMOLT44.8404.750Details
BioGPS NCI60218232_atNCI 4604.6834.750Details
BioGPS NCI60218232_atNCI H2264.7984.750Details
BioGPS NCI60218232_atNCI H234.6024.750Details
BioGPS NCI60218232_atNCI H322M4.6004.750Details
BioGPS NCI60218232_atNCVADR RES4.3064.750Details
BioGPS NCI60218232_atOVCAR35.7584.750Details
BioGPS NCI60218232_atOVCAR44.7944.750Details
BioGPS NCI60218232_atOVCAR54.4964.750Details
BioGPS NCI60218232_atOVCAR84.2854.750Details
BioGPS NCI60218232_atPANC14.7074.750Details
BioGPS NCI60218232_atRL74.6834.750Details
BioGPS NCI60218232_atRPMI 82264.6774.750Details
BioGPS NCI60218232_atRS118464.9534.750Details
BioGPS NCI60218232_atRXF3934.6004.750Details
BioGPS NCI60218232_atSAOS24.7284.750Details
BioGPS NCI60218232_atSF2684.5574.750Details
BioGPS NCI60218232_atSF2954.4864.750Details
BioGPS NCI60218232_atSF5394.4784.750Details
BioGPS NCI60218232_atSHSYSY+RA4.4024.750Details
BioGPS NCI60218232_atSHSYSY-RA4.4424.750Details
BioGPS NCI60218232_atSKMEL24.5404.750Details
BioGPS NCI60218232_atSKMEL284.6294.750Details
BioGPS NCI60218232_atSKMEL54.4164.750Details
BioGPS NCI60218232_atSKOV34.7034.750Details
BioGPS NCI60218232_atSN12C4.5564.750Details
BioGPS NCI60218232_atSNB194.3354.750Details
BioGPS NCI60218232_atSNB754.5394.750Details
BioGPS NCI60218232_atSR4.8994.750Details
BioGPS NCI60218232_atSW6204.7084.750Details
BioGPS NCI60218232_atT244.6984.750Details
BioGPS NCI60218232_atT3M44.8714.750Details
BioGPS NCI60218232_atTK104.6024.750Details
BioGPS NCI60218232_atU1184.5564.750Details
BioGPS NCI60218232_atU1384.3314.750Details
BioGPS NCI60218232_atU20S4.5854.750Details
BioGPS NCI60218232_atU2514.5184.750Details
BioGPS NCI60218232_atU874.4334.750Details
BioGPS NCI60218232_atUACC2574.4844.750Details
BioGPS NCI60218232_atUACC624.6544.750Details
BioGPS NCI60218232_atUO314.4374.750Details
BioGPS NCI60218232_atZR75_14.6984.750Details
BioGPS NCI60218232_atastrocytes4.6994.750Details
BioGPS NCI60218232_athuh-74.7414.750Details