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Gene ID: 348110 | C15orf38 Antibody Resource


C15orf38 Antibody Resource
Gene Full Name: 
chromosome 15 open reading frame 38
Uniprot: 
Q7Z6K5
Protein Name: 
arpin
Nucleotide: 
NM_182616
Alias: 
Arpin;
Ensembl: 
Location: 
15q26.1
HPRD: 
14697
NCBI Gene: 
348110
MIM: 
615543

Summary: 
Function: 
Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex. Involved in steering cell migration by controlling its directional persistence.
Subcellular location: 
Cell projection › lamellipodium. Note: Colocalized with the WAVE complex at lamelliupodium tip .
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB00858 C15orf38 antibody - N-terminal region (OAAB00858) Human; Mouse WB, ELISA 400ul $289 Details
Polyclonal Antibody ARP55835_P050 C15orf38 Antibody (ARP55835_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details

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C15orf38 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP55834 Chimpanzee C15orf38 antibody; Pan troglodytes C15orf38 antibody K7CYJ1 100.0%
ARP55835 Chimpanzee C15orf38 antibody; Pan troglodytes C15orf38 antibody K7CYJ1 100.0%
ARP55835 Human C15orf38 antibody; Homo sapiens C15orf38 antibody H0YMP5 100.0%
ARP55834 Rhesus macaque C15orf38 antibody; Macaca mulatta C15orf38 antibody H9EX57 100.0%
ARP55835 Rhesus macaque C15orf38 antibody; Macaca mulatta C15orf38 antibody H9EX57 100.0%
ARP55835 Sea lamprey C15orf38 antibody; Petromyzon marinus C15orf38 antibody S4RAX3 86.0%
ARP55834 Spotted green pufferfish C15orf38 antibody; Tetraodon nigroviridis C15orf38 antibody H3CDY0 85.0%
ARP55835 Spotted green pufferfish C15orf38 antibody; Tetraodon nigroviridis C15orf38 antibody H3CDY0 79.0%
ARP55834 White-tufted-ear marmoset C15orf38 antibody; Callithrix jacchus C15orf38 antibody U3DQX5 100.0%
ARP55835 White-tufted-ear marmoset C15orf38 antibody; Callithrix jacchus C15orf38 antibody U3DQX5 100.0%
ARP55834 White-tufted-ear marmoset C15orf38 antibody; Callithrix jacchus C15orf38 antibody U3FN27 100.0%
ARP55835 White-tufted-ear marmoset C15orf38 antibody; Callithrix jacchus C15orf38 antibody U3FN27 100.0%

Tissue & Cell Line Gene Expression Data