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Gene ID: 79697 | C14ORF169 Antibody Resource


C14ORF169 Antibody Resource
Gene Full Name: 
chromosome 14 open reading frame 169
Uniprot: 
Q9H6W3
Protein Name: 
bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66
Nucleotide: 
NM_024644
Alias: 
ROX;NO66;MAPJD;
Ensembl: 
Location: 
14q24.3
HPRD: 
12641
NCBI Gene: 
79697
MIM: 
611919

Summary: 
Function: 
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation . May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region. Participates in MYC-induced transcriptional activation.
Subcellular location: 
Nucleus › nucleolus. Nucleus › nucleoplasm. Note: Granular part of nucleoli. Nucleoplasm, nucleoplasmic foci, some of them associated with nucleoli.
PTM: 
Acetylation;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP33580_T100 C14ORF169 antibody - N-terminal region (ARP33580_T100) Polyclonal Dog WB 100ug $229 Details
Polyclonal Antibody OAEB02105 Goat Anti-C14orf169 / NO66 Antibody (OAEB02105) Dog WB 0.1mg $289 Details
Polyclonal Antibody ARP33581_P050 C14orf169 Antibody (ARP33581_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $50 Details

Show all C14ORF169 antibodies


Product Images
C14ORF169 antibody - N-terminal region (ARP33580_T100) in Human HepG2 cells using Western Blot

Sample Type: Human HepG2

Goat Anti-C14orf169 / NO66 Antibody (OAEB02105) in A431 cells using Western Blot

Sample Type: A431


C14ORF169 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP33580 Chimpanzee C14ORF169 antibody; Pan troglodytes C14ORF169 antibody K7B0B3 100.0%
ARP33581 Chimpanzee C14ORF169 antibody; Pan troglodytes C14ORF169 antibody K7B0B3 100.0%
ARP33581 Dog C14ORF169 antibody; Canis familiaris C14ORF169 antibody E2QT62 100.0%
ARP33580 Dog C14ORF169 antibody; Canis familiaris C14ORF169 antibody E2QT62 92.0%
ARP33581 Rhesus macaque C14ORF169 antibody; Macaca mulatta C14ORF169 antibody H9F800 100.0%
ARP33580 Rhesus macaque C14ORF169 antibody; Macaca mulatta C14ORF169 antibody H9ZDL1 100.0%
ARP33581 Rhesus macaque C14ORF169 antibody; Macaca mulatta C14ORF169 antibody H9ZDL1 100.0%
ARP33581 White-tufted-ear marmoset C14ORF169 antibody; Callithrix jacchus C14ORF169 antibody U3DFT3 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas219526_at721_B_lymphoblasts16.8505.820Details
BioGPS Gene Atlas219526_atAdipocyte4.2005.820Details
BioGPS Gene Atlas219526_atAdrenalCortex4.0505.820Details
BioGPS Gene Atlas219526_atAdrenalgland3.3005.820Details
BioGPS Gene Atlas219526_atAmygdala4.1005.820Details
BioGPS Gene Atlas219526_atAppendix3.8005.820Details
BioGPS Gene Atlas219526_atAtrioventricularNode2.9505.820Details
BioGPS Gene Atlas219526_atBDCA4+_DentriticCells6.5505.820Details
BioGPS Gene Atlas219526_atBonemarrow4.1005.820Details
BioGPS Gene Atlas219526_atBronchialEpithelialCells10.3005.820Details
BioGPS Gene Atlas219526_atCD105+_Endothelial14.5005.820Details
BioGPS Gene Atlas219526_atCD14+_Monocytes5.0505.820Details
BioGPS Gene Atlas219526_atCD19+_BCells(neg._sel.)7.6005.820Details
BioGPS Gene Atlas219526_atCD33+_Myeloid5.1505.820Details
BioGPS Gene Atlas219526_atCD34+22.0005.820Details
BioGPS Gene Atlas219526_atCD4+_Tcells10.1005.820Details
BioGPS Gene Atlas219526_atCD56+_NKCells11.4505.820Details
BioGPS Gene Atlas219526_atCD71+_EarlyErythroid3.7005.820Details
BioGPS Gene Atlas219526_atCD8+_Tcells10.0505.820Details
BioGPS Gene Atlas219526_atCardiacMyocytes5.4005.820Details
BioGPS Gene Atlas219526_atCaudatenucleus3.4505.820Details
BioGPS Gene Atlas219526_atCerebellum5.2005.820Details
BioGPS Gene Atlas219526_atCerebellumPeduncles4.3505.820Details
BioGPS Gene Atlas219526_atCiliaryGanglion2.9505.820Details
BioGPS Gene Atlas219526_atCingulateCortex3.9005.820Details
BioGPS Gene Atlas219526_atColorectaladenocarcinoma4.7505.820Details
BioGPS Gene Atlas219526_atDorsalRootGanglion2.9505.820Details
BioGPS Gene Atlas219526_atFetalThyroid3.9505.820Details
BioGPS Gene Atlas219526_atFetalbrain4.0505.820Details
BioGPS Gene Atlas219526_atFetalliver3.7505.820Details
BioGPS Gene Atlas219526_atFetallung3.3005.820Details
BioGPS Gene Atlas219526_atGlobusPallidus2.8505.820Details
BioGPS Gene Atlas219526_atHeart5.0505.820Details
BioGPS Gene Atlas219526_atHypothalamus4.2505.820Details
BioGPS Gene Atlas219526_atKidney3.1005.820Details
BioGPS Gene Atlas219526_atLeukemia_chronicMyelogenousK-5623.6005.820Details
BioGPS Gene Atlas219526_atLeukemia_promyelocytic-HL-609.7505.820Details
BioGPS Gene Atlas219526_atLeukemialymphoblastic(MOLT-4)10.1005.820Details
BioGPS Gene Atlas219526_atLiver5.0505.820Details
BioGPS Gene Atlas219526_atLung4.5005.820Details
BioGPS Gene Atlas219526_atLymphnode3.4505.820Details
BioGPS Gene Atlas219526_atLymphoma_burkitts(Daudi)13.3005.820Details
BioGPS Gene Atlas219526_atLymphoma_burkitts(Raji)5.4505.820Details
BioGPS Gene Atlas219526_atMedullaOblongata3.5505.820Details
BioGPS Gene Atlas219526_atOccipitalLobe3.5505.820Details
BioGPS Gene Atlas219526_atOlfactoryBulb3.0505.820Details
BioGPS Gene Atlas219526_atOvary2.6005.820Details
BioGPS Gene Atlas219526_atPancreas3.1505.820Details
BioGPS Gene Atlas219526_atPancreaticIslet4.2005.820Details
BioGPS Gene Atlas219526_atParietalLobe3.9505.820Details
BioGPS Gene Atlas219526_atPituitary4.6505.820Details
BioGPS Gene Atlas219526_atPlacenta4.5005.820Details
BioGPS Gene Atlas219526_atPons3.6505.820Details
BioGPS Gene Atlas219526_atPrefrontalCortex5.5005.820Details
BioGPS Gene Atlas219526_atProstate4.6505.820Details
BioGPS Gene Atlas219526_atSalivarygland3.1505.820Details
BioGPS Gene Atlas219526_atSkeletalMuscle4.3505.820Details
BioGPS Gene Atlas219526_atSkin2.9505.820Details
BioGPS Gene Atlas219526_atSmoothMuscle5.2505.820Details
BioGPS Gene Atlas219526_atSpinalcord4.1005.820Details
BioGPS Gene Atlas219526_atSubthalamicNucleus3.5505.820Details
BioGPS Gene Atlas219526_atSuperiorCervicalGanglion4.3005.820Details
BioGPS Gene Atlas219526_atTemporalLobe3.5005.820Details
BioGPS Gene Atlas219526_atTestis32.7505.820Details
BioGPS Gene Atlas219526_atTestisGermCell8.7005.820Details
BioGPS Gene Atlas219526_atTestisIntersitial4.9005.820Details
BioGPS Gene Atlas219526_atTestisLeydigCell4.6005.820Details
BioGPS Gene Atlas219526_atTestisSeminiferousTubule8.4005.820Details
BioGPS Gene Atlas219526_atThalamus3.9005.820Details
BioGPS Gene Atlas219526_atThymus23.9505.820Details
BioGPS Gene Atlas219526_atThyroid4.8505.820Details
BioGPS Gene Atlas219526_atTongue3.7505.820Details
BioGPS Gene Atlas219526_atTonsil4.2505.820Details
BioGPS Gene Atlas219526_atTrachea3.3005.820Details
BioGPS Gene Atlas219526_atTrigeminalGanglion3.8505.820Details
BioGPS Gene Atlas219526_atUterus3.2005.820Details
BioGPS Gene Atlas219526_atUterusCorpus3.4505.820Details
BioGPS Gene Atlas219526_atWholeBlood4.6005.820Details
BioGPS Gene Atlas219526_atWholebrain5.0005.820Details
BioGPS Gene Atlas219526_atcolon3.9505.820Details
BioGPS Gene Atlas219526_atpineal_day4.9005.820Details
BioGPS Gene Atlas219526_atpineal_night4.7205.820Details
BioGPS Gene Atlas219526_atretina5.1505.820Details
BioGPS Gene Atlas219526_atsmall_intestine3.8505.820Details
BioGPS NCI60219526_at786165.600141.590Details
BioGPS NCI60219526_atA17291.707141.590Details
BioGPS NCI60219526_atA204512.306141.590Details
BioGPS NCI60219526_atA361184.150141.590Details
BioGPS NCI60219526_atA49850.953141.590Details
BioGPS NCI60219526_atA549183.898141.590Details
BioGPS NCI60219526_atACC380.943141.590Details
BioGPS NCI60219526_atACHN88.896141.590Details
BioGPS NCI60219526_atALVA31127.049141.590Details
BioGPS NCI60219526_atCAKI160.913141.590Details
BioGPS NCI60219526_atCCRT CEM120.636141.590Details
BioGPS NCI60219526_atCOLO205186.183141.590Details
BioGPS NCI60219526_atDLD1168.279141.590Details
BioGPS NCI60219526_atDU145410.809141.590Details
BioGPS NCI60219526_atEKVX292.666141.590Details
BioGPS NCI60219526_atGM133117.182141.590Details
BioGPS NCI60219526_atGM1600117.620141.590Details
BioGPS NCI60219526_atGM231338.184141.590Details
BioGPS NCI60219526_atGM234527.658141.590Details
BioGPS NCI60219526_atGM24935.939141.590Details
BioGPS NCI60219526_atGM9720.496141.590Details
BioGPS NCI60219526_atHCC2998219.539141.590Details
BioGPS NCI60219526_atHCT11652.737141.590Details
BioGPS NCI60219526_atHCT15143.432141.590Details
BioGPS NCI60219526_atHEK 293 T-rex184.798141.590Details
BioGPS NCI60219526_atHEK 293T4.686141.590Details
BioGPS NCI60219526_atHEK293101.300141.590Details
BioGPS NCI60219526_atHELA285.785141.590Details
BioGPS NCI60219526_atHEPG2264.095141.590Details
BioGPS NCI60219526_atHL60157.668141.590Details
BioGPS NCI60219526_atHOP62129.691141.590Details
BioGPS NCI60219526_atHOP92114.510141.590Details
BioGPS NCI60219526_atHS578T107.368141.590Details
BioGPS NCI60219526_atHSG112.177141.590Details
BioGPS NCI60219526_atHT10804.672141.590Details
BioGPS NCI60219526_atHT2940.458141.590Details
BioGPS NCI60219526_atIGROV1248.227141.590Details
BioGPS NCI60219526_atIOSE80185.605141.590Details
BioGPS NCI60219526_atJURKAT245.836141.590Details
BioGPS NCI60219526_atK562101.469141.590Details
BioGPS NCI60219526_atKM1265.845141.590Details
BioGPS NCI60219526_atLN186.712141.590Details
BioGPS NCI60219526_atLNCAP4.750141.590Details
BioGPS NCI60219526_atLOX IMVI150.819141.590Details
BioGPS NCI60219526_atM14113.189141.590Details
BioGPS NCI60219526_atMALME 3M194.179141.590Details
BioGPS NCI60219526_atMCF7408.014141.590Details
BioGPS NCI60219526_atMD MB231239.043141.590Details
BioGPS NCI60219526_atMDA MB435292.379141.590Details
BioGPS NCI60219526_atMOLT4249.022141.590Details
BioGPS NCI60219526_atNCI 460175.222141.590Details
BioGPS NCI60219526_atNCI H226145.205141.590Details
BioGPS NCI60219526_atNCI H23147.283141.590Details
BioGPS NCI60219526_atNCI H322M127.252141.590Details
BioGPS NCI60219526_atNCVADR RES95.042141.590Details
BioGPS NCI60219526_atOVCAR3834.481141.590Details
BioGPS NCI60219526_atOVCAR4202.824141.590Details
BioGPS NCI60219526_atOVCAR5166.557141.590Details
BioGPS NCI60219526_atOVCAR8116.010141.590Details
BioGPS NCI60219526_atPANC134.315141.590Details
BioGPS NCI60219526_atRL7191.933141.590Details
BioGPS NCI60219526_atRPMI 822698.662141.590Details
BioGPS NCI60219526_atRS11846117.823141.590Details
BioGPS NCI60219526_atRXF393295.082141.590Details
BioGPS NCI60219526_atSAOS2124.013141.590Details
BioGPS NCI60219526_atSF26824.780141.590Details
BioGPS NCI60219526_atSF29559.217141.590Details
BioGPS NCI60219526_atSF53953.788141.590Details
BioGPS NCI60219526_atSHSYSY+RA183.690141.590Details
BioGPS NCI60219526_atSHSYSY-RA92.164141.590Details
BioGPS NCI60219526_atSKMEL2355.205141.590Details
BioGPS NCI60219526_atSKMEL2828.020141.590Details
BioGPS NCI60219526_atSKMEL5133.150141.590Details
BioGPS NCI60219526_atSKOV3699.376141.590Details
BioGPS NCI60219526_atSN12C85.907141.590Details
BioGPS NCI60219526_atSNB195.200141.590Details
BioGPS NCI60219526_atSNB756.011141.590Details
BioGPS NCI60219526_atSR167.430141.590Details
BioGPS NCI60219526_atSW620168.136141.590Details
BioGPS NCI60219526_atT24219.783141.590Details
BioGPS NCI60219526_atT3M418.339141.590Details
BioGPS NCI60219526_atTK10115.056141.590Details
BioGPS NCI60219526_atU1187.359141.590Details
BioGPS NCI60219526_atU1385.680141.590Details
BioGPS NCI60219526_atU20S247.238141.590Details
BioGPS NCI60219526_atU25118.315141.590Details
BioGPS NCI60219526_atU8756.313141.590Details
BioGPS NCI60219526_atUACC257216.340141.590Details
BioGPS NCI60219526_atUACC62241.063141.590Details
BioGPS NCI60219526_atUO3118.910141.590Details
BioGPS NCI60219526_atZR75_1201.358141.590Details
BioGPS NCI60219526_atastrocytes95.221141.590Details
BioGPS NCI60219526_athuh-756.617141.590Details