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Gene ID: 684 | BST2 Antibody Resource


BST2 Antibody Resource
Gene Full Name: 
bone marrow stromal cell antigen 2
Uniprot: 
Q10589
Protein Name: 
bone marrow stromal antigen 2
Nucleotide: 
XM_005260039
Alias: 
CD317;TETHERIN;
Ensembl: 
ENSG00000130303
Location: 
19p13.1
HPRD: 
02759
NCBI Gene: 
684
MIM: 
600534

Summary: 
Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq, Jul 2008]
Function: 
IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells. Acts as a direct physical tether, holding virions to the cell membrane and linking virions to each other. The tethered virions can be internalized by endocytosis and subsequently degraded or they can remain on the cell surface. In either case, their spread as cell-free virions is restricted. Its target viruses belong to diverse families, including retroviridae: human immunodeficiency virus type 1 (HIV-1), human immunodeficiency virus type 2 (HIV-2), simian immunodeficiency viruses (SIVs), equine infectious anemia virus (EIAV), feline immunodeficiency virus (FIV), prototype foamy virus (PFV), Mason-Pfizer monkey virus (MPMV), human T-cell leukemia virus type 1 (HTLV-1), Rous sarcoma virus (RSV) and murine leukemia virus (MLV), flavivirideae: hepatitis C virus (HCV), filoviridae: ebola virus (EBOV) and marburg virus (MARV), arenaviridae: lassa virus (LASV) and machupo virus (MACV), herpesviridae: kaposis sarcoma-associated herpesvirus (KSHV), rhabdoviridae: vesicular stomatitis virus (VSV), orthomyxoviridae: influenza A virus, and paramyxoviridae: nipah virus. Can inhibit cell surface proteolytic activity of MMP14 causing decreased activation of MMP15 which results in inhibition of cell growth and migration. Can stimulate signaling by LILRA4/ILT7 and consequently provide negative feedback to the production of IFN by plasmacytoid dendritic cells in response to viral infection. Plays a role in the organization of the subapical actin cytoskeleton in polarized epithelial cells. Isoform 1 and isoform 2 are both effective viral restriction factors but have differing antiviral and signaling activities. Isoform 2 is resistant to HIV-1 Vpu-mediated degradation and restricts HIV-1 viral budding in the presence of Vpu. Isoform 1 acts as an activator of NF-kappa-B and this activity is inhibited by isoform 2.
Subcellular location: 
Golgi apparatus › trans-Golgi network. Cell membrane; Single-pass type II membrane protein. Cell membrane; Lipid-anchor › GPI-anchor. Late endosome. Membrane raft. Cytoplasm. Apical cell membrane. Note: Shuttles between the cell membrane, where it is present predominantly in membrane/lipid rafts, and the trans-Golgi network. HIV-1 VPU and HIV-2 ENV can target it to the trans-Golgi network thus sequestering it away from virus assembly sites on the cell membrane. Targeted to late endosomes upon KSHV infection and subsequent ubiquitination. Forms a complex with MMP14 and localizes to the cytoplasm.
PTM: 
Disulfide bond;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAEB01646 Goat Anti-Tetherin / CD317 Antibody (OAEB01646) Human WB 0.1mg $289 Details
Polyclonal Antibody ARP61461_P050 BST2 antibody - N-terminal region (ARP61461_P050) Human WB 50ug $289 Details
Polyclonal Antibody OAPB00705 Bst2 Antibody (OAPB00705) Polyclonal Human; Mouse ELISA, WB 0.1 mg $300 Details
Others OOPA00070 BST2 Human - Recombinant Human Bone Marrow Stromal Cell Antigen 2 (2ug) 2ug $100 Details
Polyclonal Antibody ARP61460_P050 BST2 Antibody (ARP61460_P050) Polyclonal Human Not tested 50 ug $125 Details
Polyclonal Antibody OAAF03379 BST2 Antibody (OAAF03379) Polyclonal Human WB, ELISA 100 ug $229 Details

Show all BST2 antibodies


Product Images
BST2 antibody - N-terminal region (ARP61461_P050) in Human Fetal Lung cells using Western Blot

Sample Type: Human Fetal Lung

 BST2 Antibody (OAAF03379) in Jurkat cells using Western Blot

Sample Type: Jurkat

 Goat Anti-Tetherin / CD317 Antibody (OAEB01646) in Human spleen cells using Western Blot

Sample Type: Human spleen

 Bst2 Antibody (OAPB00705) in Daudi cells using Western Blot

Sample Type: Daudi

BST2 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP61460 Colobus guereza kikuyuensis BST2 antibody D7RVD2 93.0%
ARP61460 Agile gibbon BST2 antibody; Hylobates agilis BST2 antibody D7RVC7 100.0%
ARP61460 Angolan talapoin BST2 antibody; Miopithecus talapoin BST2 antibody D7RVD0 93.0%
ARP61460 Bornean orangutan BST2 antibody; Pongo pygmaeus BST2 antibody D7RVC5 100.0%
ARP61460 Chimpanzee BST2 antibody; Pan troglodytes BST2 antibody D7RVC2 100.0%
ARP61460 De Brazza's monkey BST2 antibody; Cercopithecus neglectus BST2 antibody I7IIB9 93.0%
ARP61460 Francois's leaf monkey BST2 antibody; Trachypithecus francoisi BST2 antibody D7RVD4 93.0%
ARP61460 Greater white-nosed monkey BST2 antibody; Cercopithecus nictitans BST2 antibody D2JNR2 93.0%
ARP61460 Green monkey BST2 antibody; Chlorocebus aethiops BST2 antibody D7RVC9 93.0%
ARP61460 Human BST2 antibody; Homo sapiens BST2 antibody Q10589-2 100.0%
ARP61460 Human BST2 antibody; Homo sapiens BST2 antibody Q10589 100.0%
ARP61460 Mona monkey BST2 antibody; Cercopithecus mona BST2 antibody D2JNR3 93.0%
ARP61460 Moustached monkey BST2 antibody; Cercopithecus cephus BST2 antibody D0EP08 93.0%
ARP61460 Moustached monkey BST2 antibody; Cercopithecus cephus BST2 antibody D2JNR4 93.0%
ARP61460 Northern white-cheeked gibbon BST2 antibody; Nomascus leucogenys BST2 antibody D7RVC6 100.0%
ARP61460 Pygmy chimpanzee BST2 antibody; Pan paniscus BST2 antibody D7RVC4 100.0%
ARP61460 Red guenon BST2 antibody; Erythrocebus patas BST2 antibody D7RVC8 93.0%
ARP61460 Red-shanked douc langur BST2 antibody; Pygathrix nemaeus BST2 antibody D7RVD3 93.0%
ARP61460 Rhesus macaque BST2 antibody; Macaca mulatta BST2 antibody C3W5K8 93.0%
ARP61460 Rhesus macaque BST2 antibody; Macaca mulatta BST2 antibody C4P4A2 93.0%
ARP61460 Rhesus macaque BST2 antibody; Macaca mulatta BST2 antibody G0WVJ8 93.0%
ARP61460 Rhesus macaque BST2 antibody; Macaca mulatta BST2 antibody D7RVD1 86.0%
ARP61460 Sooty mangabey BST2 antibody; Cercocebus atys BST2 antibody C3VHQ4 93.0%
ARP61460 Sooty mangabey BST2 antibody; Cercocebus atys BST2 antibody C3VHQ5 93.0%
ARP61460 Sumatran orangutan BST2 antibody; Pongo abelii BST2 antibody K7ETD2 100.0%
ARP61460 western gorilla BST2 antibody; Gorilla gorilla BST2 antibody D2JNR5 100.0%
ARP61460 western gorilla BST2 antibody; Gorilla gorilla BST2 antibody D7RVC3 100.0%
ARP61460 White-tufted-ear marmoset BST2 antibody; Callithrix jacchus BST2 antibody F7IEE3 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas201641_at721_B_lymphoblasts965.35086.640Details
BioGPS Gene Atlas201641_atAdipocyte6.15086.640Details
BioGPS Gene Atlas201641_atAdrenalCortex156.80086.640Details
BioGPS Gene Atlas201641_atAdrenalgland313.25086.640Details
BioGPS Gene Atlas201641_atAmygdala6.30086.640Details
BioGPS Gene Atlas201641_atAppendix9.10086.640Details
BioGPS Gene Atlas201641_atAtrioventricularNode4.75086.640Details
BioGPS Gene Atlas201641_atBDCA4+_DentriticCells624.40086.640Details
BioGPS Gene Atlas201641_atBonemarrow12.20086.640Details
BioGPS Gene Atlas201641_atBronchialEpithelialCells5.05086.640Details
BioGPS Gene Atlas201641_atCD105+_Endothelial38.90086.640Details
BioGPS Gene Atlas201641_atCD14+_Monocytes580.95086.640Details
BioGPS Gene Atlas201641_atCD19+_BCells(neg._sel.)160.15086.640Details
BioGPS Gene Atlas201641_atCD33+_Myeloid572.30086.640Details
BioGPS Gene Atlas201641_atCD34+254.20086.640Details
BioGPS Gene Atlas201641_atCD4+_Tcells174.65086.640Details
BioGPS Gene Atlas201641_atCD56+_NKCells440.45086.640Details
BioGPS Gene Atlas201641_atCD71+_EarlyErythroid6.00086.640Details
BioGPS Gene Atlas201641_atCD8+_Tcells167.10086.640Details
BioGPS Gene Atlas201641_atCardiacMyocytes6.85086.640Details
BioGPS Gene Atlas201641_atCaudatenucleus6.05086.640Details
BioGPS Gene Atlas201641_atCerebellum5.05086.640Details
BioGPS Gene Atlas201641_atCerebellumPeduncles7.25086.640Details
BioGPS Gene Atlas201641_atCiliaryGanglion5.15086.640Details
BioGPS Gene Atlas201641_atCingulateCortex6.45086.640Details
BioGPS Gene Atlas201641_atColorectaladenocarcinoma6.45086.640Details
BioGPS Gene Atlas201641_atDorsalRootGanglion4.85086.640Details
BioGPS Gene Atlas201641_atFetalThyroid6.15086.640Details
BioGPS Gene Atlas201641_atFetalbrain6.15086.640Details
BioGPS Gene Atlas201641_atFetalliver5.75086.640Details
BioGPS Gene Atlas201641_atFetallung9.80086.640Details
BioGPS Gene Atlas201641_atGlobusPallidus4.85086.640Details
BioGPS Gene Atlas201641_atHeart136.85086.640Details
BioGPS Gene Atlas201641_atHypothalamus9.10086.640Details
BioGPS Gene Atlas201641_atKidney8.70086.640Details
BioGPS Gene Atlas201641_atLeukemia_chronicMyelogenousK-56252.75086.640Details
BioGPS Gene Atlas201641_atLeukemia_promyelocytic-HL-60122.90086.640Details
BioGPS Gene Atlas201641_atLeukemialymphoblastic(MOLT-4)12.50086.640Details
BioGPS Gene Atlas201641_atLiver186.95086.640Details
BioGPS Gene Atlas201641_atLung359.20086.640Details
BioGPS Gene Atlas201641_atLymphnode86.50086.640Details
BioGPS Gene Atlas201641_atLymphoma_burkitts(Daudi)466.60086.640Details
BioGPS Gene Atlas201641_atLymphoma_burkitts(Raji)342.90086.640Details
BioGPS Gene Atlas201641_atMedullaOblongata5.75086.640Details
BioGPS Gene Atlas201641_atOccipitalLobe5.70086.640Details
BioGPS Gene Atlas201641_atOlfactoryBulb14.65086.640Details
BioGPS Gene Atlas201641_atOvary385.50086.640Details
BioGPS Gene Atlas201641_atPancreas40.35086.640Details
BioGPS Gene Atlas201641_atPancreaticIslet7.05086.640Details
BioGPS Gene Atlas201641_atParietalLobe6.70086.640Details
BioGPS Gene Atlas201641_atPituitary7.65086.640Details
BioGPS Gene Atlas201641_atPlacenta152.50086.640Details
BioGPS Gene Atlas201641_atPons6.05086.640Details
BioGPS Gene Atlas201641_atPrefrontalCortex9.35086.640Details
BioGPS Gene Atlas201641_atProstate67.65086.640Details
BioGPS Gene Atlas201641_atSalivarygland5.10086.640Details
BioGPS Gene Atlas201641_atSkeletalMuscle7.15086.640Details
BioGPS Gene Atlas201641_atSkin5.00086.640Details
BioGPS Gene Atlas201641_atSmoothMuscle6.95086.640Details
BioGPS Gene Atlas201641_atSpinalcord11.35086.640Details
BioGPS Gene Atlas201641_atSubthalamicNucleus5.75086.640Details
BioGPS Gene Atlas201641_atSuperiorCervicalGanglion6.95086.640Details
BioGPS Gene Atlas201641_atTemporalLobe5.85086.640Details
BioGPS Gene Atlas201641_atTestis6.45086.640Details
BioGPS Gene Atlas201641_atTestisGermCell5.20086.640Details
BioGPS Gene Atlas201641_atTestisIntersitial5.40086.640Details
BioGPS Gene Atlas201641_atTestisLeydigCell6.65086.640Details
BioGPS Gene Atlas201641_atTestisSeminiferousTubule5.55086.640Details
BioGPS Gene Atlas201641_atThalamus6.80086.640Details
BioGPS Gene Atlas201641_atThymus134.20086.640Details
BioGPS Gene Atlas201641_atThyroid8.25086.640Details
BioGPS Gene Atlas201641_atTongue6.20086.640Details
BioGPS Gene Atlas201641_atTonsil12.80086.640Details
BioGPS Gene Atlas201641_atTrachea9.80086.640Details
BioGPS Gene Atlas201641_atTrigeminalGanglion6.75086.640Details
BioGPS Gene Atlas201641_atUterus69.20086.640Details
BioGPS Gene Atlas201641_atUterusCorpus5.45086.640Details
BioGPS Gene Atlas201641_atWholeBlood65.40086.640Details
BioGPS Gene Atlas201641_atWholebrain5.85086.640Details
BioGPS Gene Atlas201641_atcolon7.10086.640Details
BioGPS Gene Atlas201641_atpineal_day9.34086.640Details
BioGPS Gene Atlas201641_atpineal_night8.36086.640Details
BioGPS Gene Atlas201641_atretina31.52586.640Details
BioGPS Gene Atlas201641_atsmall_intestine23.50086.640Details
BioGPS NCI60201641_at78667.931380.310Details
BioGPS NCI60201641_atA1727.279380.310Details
BioGPS NCI60201641_atA2044.346380.310Details
BioGPS NCI60201641_atA3614.319380.310Details
BioGPS NCI60201641_atA498717.992380.310Details
BioGPS NCI60201641_atA5494.371380.310Details
BioGPS NCI60201641_atACC31071.899380.310Details
BioGPS NCI60201641_atACHN3.998380.310Details
BioGPS NCI60201641_atALVA314.579380.310Details
BioGPS NCI60201641_atCAKI15.421380.310Details
BioGPS NCI60201641_atCCRT CEM6.157380.310Details
BioGPS NCI60201641_atCOLO205136.854380.310Details
BioGPS NCI60201641_atDLD14.192380.310Details
BioGPS NCI60201641_atDU1454.103380.310Details
BioGPS NCI60201641_atEKVX4.103380.310Details
BioGPS NCI60201641_atGM1334.634380.310Details
BioGPS NCI60201641_atGM16004.716380.310Details
BioGPS NCI60201641_atGM23132940.204380.310Details
BioGPS NCI60201641_atGM23454.906380.310Details
BioGPS NCI60201641_atGM24934.528380.310Details
BioGPS NCI60201641_atGM97966.652380.310Details
BioGPS NCI60201641_atHCC29983.860380.310Details
BioGPS NCI60201641_atHCT1164.327380.310Details
BioGPS NCI60201641_atHCT154.047380.310Details
BioGPS NCI60201641_atHEK 293 T-rex4.875380.310Details
BioGPS NCI60201641_atHEK 293T4.247380.310Details
BioGPS NCI60201641_atHEK29394.050380.310Details
BioGPS NCI60201641_atHELA2309.844380.310Details
BioGPS NCI60201641_atHEPG257.211380.310Details
BioGPS NCI60201641_atHL60445.602380.310Details
BioGPS NCI60201641_atHOP62423.543380.310Details
BioGPS NCI60201641_atHOP926.949380.310Details
BioGPS NCI60201641_atHS578T4.222380.310Details
BioGPS NCI60201641_atHSG1184.147380.310Details
BioGPS NCI60201641_atHT10804.209380.310Details
BioGPS NCI60201641_atHT29410.263380.310Details
BioGPS NCI60201641_atIGROV11947.916380.310Details
BioGPS NCI60201641_atIOSE805.331380.310Details
BioGPS NCI60201641_atJURKAT33.812380.310Details
BioGPS NCI60201641_atK562515.084380.310Details
BioGPS NCI60201641_atKM125.989380.310Details
BioGPS NCI60201641_atLN18458.094380.310Details
BioGPS NCI60201641_atLNCAP4.279380.310Details
BioGPS NCI60201641_atLOX IMVI5.464380.310Details
BioGPS NCI60201641_atM1412.106380.310Details
BioGPS NCI60201641_atMALME 3M60.585380.310Details
BioGPS NCI60201641_atMCF7774.482380.310Details
BioGPS NCI60201641_atMD MB231593.945380.310Details
BioGPS NCI60201641_atMDA MB435312.593380.310Details
BioGPS NCI60201641_atMOLT464.227380.310Details
BioGPS NCI60201641_atNCI 4604.391380.310Details
BioGPS NCI60201641_atNCI H226758.821380.310Details
BioGPS NCI60201641_atNCI H234.264380.310Details
BioGPS NCI60201641_atNCI H322M4.371380.310Details
BioGPS NCI60201641_atNCVADR RES1449.009380.310Details
BioGPS NCI60201641_atOVCAR3224.703380.310Details
BioGPS NCI60201641_atOVCAR4196.421380.310Details
BioGPS NCI60201641_atOVCAR5354.291380.310Details
BioGPS NCI60201641_atOVCAR8799.411380.310Details
BioGPS NCI60201641_atPANC15.313380.310Details
BioGPS NCI60201641_atRL7716.123380.310Details
BioGPS NCI60201641_atRPMI 82262834.940380.310Details
BioGPS NCI60201641_atRS11846882.325380.310Details
BioGPS NCI60201641_atRXF3933882.704380.310Details
BioGPS NCI60201641_atSAOS24.326380.310Details
BioGPS NCI60201641_atSF2685.058380.310Details
BioGPS NCI60201641_atSF2954.183380.310Details
BioGPS NCI60201641_atSF5391677.348380.310Details
BioGPS NCI60201641_atSHSYSY+RA4.135380.310Details
BioGPS NCI60201641_atSHSYSY-RA4.278380.310Details
BioGPS NCI60201641_atSKMEL218.281380.310Details
BioGPS NCI60201641_atSKMEL28161.981380.310Details
BioGPS NCI60201641_atSKMEL54.109380.310Details
BioGPS NCI60201641_atSKOV328.638380.310Details
BioGPS NCI60201641_atSN12C316.009380.310Details
BioGPS NCI60201641_atSNB194.871380.310Details
BioGPS NCI60201641_atSNB754.243380.310Details
BioGPS NCI60201641_atSR2035.526380.310Details
BioGPS NCI60201641_atSW6205.290380.310Details
BioGPS NCI60201641_atT24530.509380.310Details
BioGPS NCI60201641_atT3M41646.014380.310Details
BioGPS NCI60201641_atTK104.271380.310Details
BioGPS NCI60201641_atU11838.462380.310Details
BioGPS NCI60201641_atU1384.021380.310Details
BioGPS NCI60201641_atU20S7.789380.310Details
BioGPS NCI60201641_atU2511442.956380.310Details
BioGPS NCI60201641_atU874.152380.310Details
BioGPS NCI60201641_atUACC25756.532380.310Details
BioGPS NCI60201641_atUACC622130.463380.310Details
BioGPS NCI60201641_atUO314.181380.310Details
BioGPS NCI60201641_atZR75_11226.509380.310Details
BioGPS NCI60201641_atastrocytes4.266380.310Details
BioGPS NCI60201641_athuh-74.404380.310Details

 

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