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Gene ID: 254065 | BRWD3 Antibody Resource


BRWD3 Antibody Resource
Gene Full Name: 
bromodomain and WD repeat domain containing 3
Uniprot: 
Q6RI45
Protein Name: 
bromodomain and WD repeat-containing protein 3
Nucleotide: 
NM_153252
Alias: 
BRODL;MRX93;
Ensembl: 
ENSG00000165288
Location: 
Xq21.1
HPRD: 
06564
NCBI Gene: 
254065
MIM: 
300553

Summary: 
The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene cause mental retardation X-linked type 93, which is also referred to as mental retardation X-linked with macrocephaly. This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia. [provided by RefSeq, May 2010]
Function: 
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
Subcellular location: 
PTM: 
Phosphoprotein;
Disease: 
A chromosomal aberration involving BRWD3 can be found in patients with B-cell chronic lymphocytic leukemia (B-CLL). Translocation t(X;11)(q21;q23) with ARHGAP20 does not result in fusion transcripts but disrupts both genes.Mental retardation, X-linked 93 (MRX93) [MIM:300659]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation, while syndromic mental retardation presents with associated physical, neurological and/or psychiatric manifestations. MRX93 is associated with macrocephaly. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP66523_P050 BRWD3 Antibody (ARP66523_P050) Polyclonal Not tested 50 ug $125 Details
Polyclonal Antibody ARP66524_P050 BRWD3 Antibody (ARP66524_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAF03396 BRWD3 Antibody (OAAF03396) Polyclonal Human, Mouse WB, IHC, ELISA 100 ug $229 Details

Show all BRWD3 antibodies


Product Images
BRWD3 Antibody (OAAF03396) in COLO cells using Western Blot

Sample Type: COLO

BRWD3 Antibody (OAAF03396) in Human heart cells using Immunohistochemistry

Sample Type: Human heart


BRWD3 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP66523 Bovine BRWD3 antibody; Bos taurus BRWD3 antibody F1N1C9 92.0%
ARP66524 Bovine BRWD3 antibody; Bos taurus BRWD3 antibody F1N1C9 86.0%
ARP61176 Bovine BRWD3 antibody; Bos taurus BRWD3 antibody F1N1C9 79.0%
ARP66523 Cat BRWD3 antibody; Felis catus BRWD3 antibody M3XES2 92.0%
ARP66524 Cat BRWD3 antibody; Felis catus BRWD3 antibody M3XES2 86.0%
ARP61176 Cat BRWD3 antibody; Felis catus BRWD3 antibody M3XES2 79.0%
ARP61176 Chicken BRWD3 antibody; Gallus gallus BRWD3 antibody F1N8L6 79.0%
ARP72563 Chicken BRWD3 antibody; Gallus gallus BRWD3 antibody F1N8L6 79.0%
ARP66523 Chimpanzee BRWD3 antibody; Pan troglodytes BRWD3 antibody K7CWG3 100.0%
ARP66524 Chimpanzee BRWD3 antibody; Pan troglodytes BRWD3 antibody K7CWG3 100.0%
ARP66523 Chimpanzee BRWD3 antibody; Pan troglodytes BRWD3 antibody H2QYU6 100.0%
ARP66524 Chimpanzee BRWD3 antibody; Pan troglodytes BRWD3 antibody H2QYU6 100.0%
ARP61176 Chimpanzee BRWD3 antibody; Pan troglodytes BRWD3 antibody K7CWG3 79.0%
ARP61176 Chimpanzee BRWD3 antibody; Pan troglodytes BRWD3 antibody H2QYU6 79.0%
ARP61176 Collared flycatcher BRWD3 antibody; Ficedula albicollis BRWD3 antibody U3JN87 79.0%
ARP66523 Dog BRWD3 antibody; Canis familiaris BRWD3 antibody J9P6J5 92.0%
ARP66523 Dog BRWD3 antibody; Canis familiaris BRWD3 antibody E2RA54 92.0%
ARP66524 Dog BRWD3 antibody; Canis familiaris BRWD3 antibody J9P6J5 86.0%
ARP66524 Dog BRWD3 antibody; Canis familiaris BRWD3 antibody E2RA54 86.0%
ARP61176 Dog BRWD3 antibody; Canis familiaris BRWD3 antibody J9P6J5 79.0%
ARP61176 Dog BRWD3 antibody; Canis familiaris BRWD3 antibody E2RA54 79.0%
ARP61176 Domestic duck BRWD3 antibody; Anas platyrhynchos BRWD3 antibody U3IQ01 79.0%
ARP66523 European domestic ferret BRWD3 antibody; Mustela putorius furo BRWD3 antibody M3YMG2 92.0%
ARP66524 European domestic ferret BRWD3 antibody; Mustela putorius furo BRWD3 antibody M3YMG2 86.0%
ARP61176 European domestic ferret BRWD3 antibody; Mustela putorius furo BRWD3 antibody M3YMG2 79.0%
ARP66523 Giant panda BRWD3 antibody; Ailuropoda melanoleuca BRWD3 antibody G1LQ43 92.0%
ARP66524 Giant panda BRWD3 antibody; Ailuropoda melanoleuca BRWD3 antibody G1LQ43 86.0%
ARP61176 Giant panda BRWD3 antibody; Ailuropoda melanoleuca BRWD3 antibody G1LQ20 79.0%
ARP61176 Giant panda BRWD3 antibody; Ailuropoda melanoleuca BRWD3 antibody G1LQ43 79.0%
ARP61176 Gray short-tailed opossum BRWD3 antibody; Monodelphis domestica BRWD3 antibody F6XNH7 79.0%
ARP66524 Horse BRWD3 antibody; Equus caballus BRWD3 antibody F7CEL8 86.0%
ARP66523 Horse BRWD3 antibody; Equus caballus BRWD3 antibody F7CEL8 83.0%
ARP61176 Horse BRWD3 antibody; Equus caballus BRWD3 antibody F7CEL8 79.0%
ARP66523 Human BRWD3 antibody; Homo sapiens BRWD3 antibody Q6RI45-2 100.0%
ARP66524 Human BRWD3 antibody; Homo sapiens BRWD3 antibody Q6RI45-2 100.0%
ARP66523 Human BRWD3 antibody; Homo sapiens BRWD3 antibody Q6RI45-3 100.0%
ARP66524 Human BRWD3 antibody; Homo sapiens BRWD3 antibody Q6RI45-3 100.0%
ARP66523 Human BRWD3 antibody; Homo sapiens BRWD3 antibody Q6RI45-4 100.0%
ARP66524 Human BRWD3 antibody; Homo sapiens BRWD3 antibody Q6RI45-4 100.0%
ARP66523 Human BRWD3 antibody; Homo sapiens BRWD3 antibody Q6RI45 100.0%
ARP66524 Human BRWD3 antibody; Homo sapiens BRWD3 antibody Q6RI45 100.0%
ARP61176 Human BRWD3 antibody; Homo sapiens BRWD3 antibody Q6RI45-2 79.0%
ARP61176 Human BRWD3 antibody; Homo sapiens BRWD3 antibody Q6RI45-3 79.0%
ARP61176 Human BRWD3 antibody; Homo sapiens BRWD3 antibody Q6RI45-4 79.0%
ARP61176 Human BRWD3 antibody; Homo sapiens BRWD3 antibody Q6RI45-5 79.0%
ARP61176 Human BRWD3 antibody; Homo sapiens BRWD3 antibody Q6RI45 79.0%
ARP66524 Mouse BRWD3 antibody; Mus musculus BRWD3 antibody A2AHJ4 93.0%
ARP66523 Mouse BRWD3 antibody; Mus musculus BRWD3 antibody A2AHJ4 83.0%
ARP61176 Mouse BRWD3 antibody; Mus musculus BRWD3 antibody A2AHJ4 79.0%
ARP61176 Nile tilapia BRWD3 antibody; Oreochromis niloticus BRWD3 antibody I3J9S1 79.0%
ARP61176 Nile tilapia BRWD3 antibody; Oreochromis niloticus BRWD3 antibody I3J9S2 79.0%
ARP66523 Northern white-cheeked gibbon BRWD3 antibody; Nomascus leucogenys BRWD3 antibody G1QPT4 100.0%
ARP66524 Northern white-cheeked gibbon BRWD3 antibody; Nomascus leucogenys BRWD3 antibody G1QPT4 100.0%
ARP61176 Northern white-cheeked gibbon BRWD3 antibody; Nomascus leucogenys BRWD3 antibody G1QPT4 79.0%
ARP61176 Rabbit BRWD3 antibody; Oryctolagus cuniculus BRWD3 antibody G1SND3 79.0%
ARP66523 Rat BRWD3 antibody; Rattus norvegicus BRWD3 antibody D3Z8C5 85.0%
ARP61176 Rat BRWD3 antibody; Rattus norvegicus BRWD3 antibody D3Z8C5 79.0%
ARP66524 Rat BRWD3 antibody; Rattus norvegicus BRWD3 antibody D3Z8C5 79.0%
ARP66523 Rhesus macaque BRWD3 antibody; Macaca mulatta BRWD3 antibody H9FJL5 100.0%
ARP66524 Rhesus macaque BRWD3 antibody; Macaca mulatta BRWD3 antibody H9FJL5 100.0%
ARP66523 Rhesus macaque BRWD3 antibody; Macaca mulatta BRWD3 antibody I2CWT1 100.0%
ARP66524 Rhesus macaque BRWD3 antibody; Macaca mulatta BRWD3 antibody I2CWT1 100.0%
ARP61176 Rhesus macaque BRWD3 antibody; Macaca mulatta BRWD3 antibody H9FJL5 79.0%
ARP61176 Rhesus macaque BRWD3 antibody; Macaca mulatta BRWD3 antibody I2CWT1 79.0%
ARP66523 Small-eared galago BRWD3 antibody; Otolemur garnettii BRWD3 antibody H0X9F7 93.0%
ARP61176 Small-eared galago BRWD3 antibody; Otolemur garnettii BRWD3 antibody H0X9F7 79.0%
ARP66524 Small-eared galago BRWD3 antibody; Otolemur garnettii BRWD3 antibody H0X9F7 79.0%
ARP61176 Spotted green pufferfish BRWD3 antibody; Tetraodon nigroviridis BRWD3 antibody H3D2N3 79.0%
ARP72563 Spotted green pufferfish BRWD3 antibody; Tetraodon nigroviridis BRWD3 antibody H3D2N3 79.0%
ARP66523 Sumatran orangutan BRWD3 antibody; Pongo abelii BRWD3 antibody H2PW48 100.0%
ARP66524 Sumatran orangutan BRWD3 antibody; Pongo abelii BRWD3 antibody H2PW48 100.0%
ARP61176 Sumatran orangutan BRWD3 antibody; Pongo abelii BRWD3 antibody H2PW48 79.0%
ARP61176 Tasmanian devil BRWD3 antibody; Sarcophilus harrisii BRWD3 antibody G3WZX2 79.0%
ARP61176 Tasmanian devil BRWD3 antibody; Sarcophilus harrisii BRWD3 antibody G3WZX3 79.0%
ARP66524 Thirteen-lined ground squirrel BRWD3 antibody; Spermophilus tridecemlineatus BRWD3 antibody I3M4H5 93.0%
ARP66523 Thirteen-lined ground squirrel BRWD3 antibody; Spermophilus tridecemlineatus BRWD3 antibody I3M4H5 86.0%
ARP61176 Thirteen-lined ground squirrel BRWD3 antibody; Spermophilus tridecemlineatus BRWD3 antibody I3M4H5 79.0%
ARP66523 White-tufted-ear marmoset BRWD3 antibody; Callithrix jacchus BRWD3 antibody U3CT08 100.0%
ARP66524 White-tufted-ear marmoset BRWD3 antibody; Callithrix jacchus BRWD3 antibody U3CT08 100.0%
ARP66523 White-tufted-ear marmoset BRWD3 antibody; Callithrix jacchus BRWD3 antibody U3DFL0 100.0%
ARP66524 White-tufted-ear marmoset BRWD3 antibody; Callithrix jacchus BRWD3 antibody U3DFL0 100.0%
ARP66523 White-tufted-ear marmoset BRWD3 antibody; Callithrix jacchus BRWD3 antibody H9KXJ7 100.0%
ARP66524 White-tufted-ear marmoset BRWD3 antibody; Callithrix jacchus BRWD3 antibody H9KXJ7 100.0%
ARP61176 White-tufted-ear marmoset BRWD3 antibody; Callithrix jacchus BRWD3 antibody U3CT08 79.0%
ARP61176 White-tufted-ear marmoset BRWD3 antibody; Callithrix jacchus BRWD3 antibody U3DFL0 79.0%
ARP61176 White-tufted-ear marmoset BRWD3 antibody; Callithrix jacchus BRWD3 antibody H9KXJ7 79.0%
ARP61176 Zebra finch BRWD3 antibody; Taeniopygia guttata BRWD3 antibody H0YWG5 79.0%
ARP61176 Zebra finch BRWD3 antibody; Taeniopygia guttata BRWD3 antibody H0YWG7 79.0%
ARP61176 Zebrafish BRWD3 antibody; Danio rerio BRWD3 antibody Q6NSN0 79.0%

Tissue & Cell Line Gene Expression Data