Search Antibody, Protein, and ELISA Kit Solutions


Gene ID: 9024 | BRSK2 Antibody Resource


BRSK2 Antibody Resource
Gene Full Name: 
BR serine/threonine kinase 2
Uniprot: 
Q8IWQ3
Protein Name: 
serine/threonine-protein kinase BRSK2
Nucleotide: 
NR_046331
Alias: 
SAD1;SADA;STK29;PEN11B;C11orf7;
Ensembl: 
ENSG00000174672
Location: 
11p15.5
HPRD: 
NCBI Gene: 
9024
MIM: 
609236

Summary: 
Function: 
Serine/threonine-protein kinase that plays a key role in polarization of neurons and axonogenesis, cell cycle progress and insulin secretion. Phosphorylates CDK16, CDC25C, MAPT/TAU, PAK1 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Thr-529' and 'Ser-579'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 activity in polarized neurons. Plays a role in the regulation of the mitotic cell cycle progress and the onset of mitosis. Plays a role in the regulation of insulin secretion in response to elevated glucose levels, probably via phosphorylation of CDK16 and PAK1. While BRSK2 phosphorylated at Thr-174 can inhibit insulin secretion (), BRSK2 phosphorylated at Thr-260 can promote insulin secretion (). Regulates reorganization of the actin cytoskeleton. May play a role in the apoptotic response triggered by endoplasmatic reticulum (ER) stress.
Subcellular location: 
Cytoplasm › cytoskeleton › microtubule organizing center › centrosome. Cytoplasm › perinuclear region. Endoplasmic reticulum. Note: Detected at centrosomes during mitosis. Localizes to the endoplasmic reticulum in response to stress caused by tunicamycin.
PTM: 
Phosphoprotein;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAEB00774 Goat Anti-BRSK2 / STK29 Antibody (OAEB00774) Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rat ELISA 0.1mg $229 Details
Polyclonal Antibody OAPB00510 BRSK2 Antibody (OAPB00510) Polyclonal Human; Mouse ELISA, WB, IHC 0.1 mg $355 Details
Polyclonal Antibody ARP58598_P050 BRSK2 Antibody (ARP58598_P050) Polyclonal Human, Mouse, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB11466 Mouse Brsk2 antibody - center region (OAAB11466) Mouse WB 400ul $289 Details
Polyclonal Antibody OAAB16965 BRSK2 (STK29) antibody - center region (OAAB16965) Human WB, IHC 400ul $289 Details
Polyclonal Antibody OAAB16966 STK29 antibody - C - terminal region (OAAB16966) Human WB, IHC 400ul $289 Details

Show all BRSK2 antibodies


Product Images
Mouse Brsk2 antibody - center region (OAAB11466) in Mouse Testis cells using Western Blot

Sample Type: Mouse Testis

STK29 antibody - C - terminal region (OAAB16966) in HL-60 cells using Western Blot

Sample Type: HL-60

STK29 antibody - C - terminal region (OAAB16966) in Human cancer, breast carcinoma, hepatocarcinoma cells using Immunohistochemistry

Sample Type: Human cancer, breast carcinoma, hepatocarcinoma

BRSK2 Antibody (OAPB00510) in Human brain cells using Western Blot

Sample Type: Human brain

BRSK2 Antibody (OAPB00510) in Human brain cells using Immunohistochemistry

Sample Type: Human brain


BRSK2 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP58598 Chicken BRSK2 antibody; Gallus gallus BRSK2 antibody R4GLQ6 87.0%
ARP58598 Human BRSK2 antibody; Homo sapiens BRSK2 antibody Q8IWQ3-2 100.0%
ARP58598 Human BRSK2 antibody; Homo sapiens BRSK2 antibody Q8IWQ3-3 100.0%
ARP58598 Human BRSK2 antibody; Homo sapiens BRSK2 antibody Q8IWQ3-4 100.0%
ARP58598 Human BRSK2 antibody; Homo sapiens BRSK2 antibody Q8IWQ3 100.0%
ARP58598 Mouse BRSK2 antibody; Mus musculus BRSK2 antibody G3FEZ6 93.0%
ARP58598 Mouse BRSK2 antibody; Mus musculus BRSK2 antibody G3UWV4 93.0%
ARP58598 Mouse BRSK2 antibody; Mus musculus BRSK2 antibody G3UZ00 93.0%
ARP58598 Mouse BRSK2 antibody; Mus musculus BRSK2 antibody Q69Z98-2 93.0%
ARP58598 Mouse BRSK2 antibody; Mus musculus BRSK2 antibody Q69Z98-3 93.0%
ARP58598 Mouse BRSK2 antibody; Mus musculus BRSK2 antibody Q69Z98-4 93.0%
ARP58598 Mouse BRSK2 antibody; Mus musculus BRSK2 antibody Q69Z98 93.0%
ARP58598 Rat BRSK2 antibody; Rattus norvegicus BRSK2 antibody D3ZML2-2 93.0%
ARP58598 Rat BRSK2 antibody; Rattus norvegicus BRSK2 antibody D3ZML2 93.0%
ARP58598 Rhesus macaque BRSK2 antibody; Macaca mulatta BRSK2 antibody H9G1I4 100.0%
ARP55682 Sumatran orangutan BRSK2 antibody; Pongo abelii BRSK2 antibody H2NCD7 83.0%
ARP58598 White-tufted-ear marmoset BRSK2 antibody; Callithrix jacchus BRSK2 antibody U3C9B8 100.0%
ARP58598 White-tufted-ear marmoset BRSK2 antibody; Callithrix jacchus BRSK2 antibody U3D3Y1 100.0%
ARP58598 White-tufted-ear marmoset BRSK2 antibody; Callithrix jacchus BRSK2 antibody U3EJG1 100.0%
ARP58598 White-tufted-ear marmoset BRSK2 antibody; Callithrix jacchus BRSK2 antibody U3EMH5 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas215010_s_at721_B_lymphoblasts7.0506.090Details
BioGPS Gene Atlas215010_s_atAdipocyte5.6506.090Details
BioGPS Gene Atlas215010_s_atAdrenalCortex6.5506.090Details
BioGPS Gene Atlas215010_s_atAdrenalgland4.9506.090Details
BioGPS Gene Atlas215010_s_atAmygdala6.2006.090Details
BioGPS Gene Atlas215010_s_atAppendix5.8006.090Details
BioGPS Gene Atlas215010_s_atAtrioventricularNode4.6006.090Details
BioGPS Gene Atlas215010_s_atBDCA4+_DentriticCells5.8006.090Details
BioGPS Gene Atlas215010_s_atBonemarrow5.6506.090Details
BioGPS Gene Atlas215010_s_atBronchialEpithelialCells5.5006.090Details
BioGPS Gene Atlas215010_s_atCD105+_Endothelial5.7506.090Details
BioGPS Gene Atlas215010_s_atCD14+_Monocytes5.9506.090Details
BioGPS Gene Atlas215010_s_atCD19+_BCells(neg._sel.)5.6006.090Details
BioGPS Gene Atlas215010_s_atCD33+_Myeloid7.2506.090Details
BioGPS Gene Atlas215010_s_atCD34+7.0506.090Details
BioGPS Gene Atlas215010_s_atCD4+_Tcells6.1506.090Details
BioGPS Gene Atlas215010_s_atCD56+_NKCells6.4506.090Details
BioGPS Gene Atlas215010_s_atCD71+_EarlyErythroid5.4006.090Details
BioGPS Gene Atlas215010_s_atCD8+_Tcells5.4006.090Details
BioGPS Gene Atlas215010_s_atCardiacMyocytes7.6006.090Details
BioGPS Gene Atlas215010_s_atCaudatenucleus7.5506.090Details
BioGPS Gene Atlas215010_s_atCerebellum6.8006.090Details
BioGPS Gene Atlas215010_s_atCerebellumPeduncles13.9506.090Details
BioGPS Gene Atlas215010_s_atCiliaryGanglion4.1506.090Details
BioGPS Gene Atlas215010_s_atCingulateCortex5.9006.090Details
BioGPS Gene Atlas215010_s_atColorectaladenocarcinoma5.6506.090Details
BioGPS Gene Atlas215010_s_atDorsalRootGanglion4.4506.090Details
BioGPS Gene Atlas215010_s_atFetalThyroid5.5006.090Details
BioGPS Gene Atlas215010_s_atFetalbrain6.6506.090Details
BioGPS Gene Atlas215010_s_atFetalliver4.9506.090Details
BioGPS Gene Atlas215010_s_atFetallung4.4506.090Details
BioGPS Gene Atlas215010_s_atGlobusPallidus6.0006.090Details
BioGPS Gene Atlas215010_s_atHeart7.5006.090Details
BioGPS Gene Atlas215010_s_atHypothalamus6.2506.090Details
BioGPS Gene Atlas215010_s_atKidney4.7506.090Details
BioGPS Gene Atlas215010_s_atLeukemia_chronicMyelogenousK-5625.2506.090Details
BioGPS Gene Atlas215010_s_atLeukemia_promyelocytic-HL-605.1006.090Details
BioGPS Gene Atlas215010_s_atLeukemialymphoblastic(MOLT-4)4.7006.090Details
BioGPS Gene Atlas215010_s_atLiver7.6506.090Details
BioGPS Gene Atlas215010_s_atLung6.0506.090Details
BioGPS Gene Atlas215010_s_atLymphnode4.9006.090Details
BioGPS Gene Atlas215010_s_atLymphoma_burkitts(Daudi)7.3506.090Details
BioGPS Gene Atlas215010_s_atLymphoma_burkitts(Raji)8.0006.090Details
BioGPS Gene Atlas215010_s_atMedullaOblongata5.6006.090Details
BioGPS Gene Atlas215010_s_atOccipitalLobe6.3006.090Details
BioGPS Gene Atlas215010_s_atOlfactoryBulb4.6006.090Details
BioGPS Gene Atlas215010_s_atOvary3.8506.090Details
BioGPS Gene Atlas215010_s_atPancreas4.6506.090Details
BioGPS Gene Atlas215010_s_atPancreaticIslet6.2006.090Details
BioGPS Gene Atlas215010_s_atParietalLobe7.3506.090Details
BioGPS Gene Atlas215010_s_atPituitary6.9006.090Details
BioGPS Gene Atlas215010_s_atPlacenta5.7006.090Details
BioGPS Gene Atlas215010_s_atPons6.2006.090Details
BioGPS Gene Atlas215010_s_atPrefrontalCortex10.2006.090Details
BioGPS Gene Atlas215010_s_atProstate6.6506.090Details
BioGPS Gene Atlas215010_s_atSalivarygland4.6006.090Details
BioGPS Gene Atlas215010_s_atSkeletalMuscle6.9006.090Details
BioGPS Gene Atlas215010_s_atSkin4.5006.090Details
BioGPS Gene Atlas215010_s_atSmoothMuscle6.4006.090Details
BioGPS Gene Atlas215010_s_atSpinalcord6.2006.090Details
BioGPS Gene Atlas215010_s_atSubthalamicNucleus8.2006.090Details
BioGPS Gene Atlas215010_s_atSuperiorCervicalGanglion6.6506.090Details
BioGPS Gene Atlas215010_s_atTemporalLobe5.4006.090Details
BioGPS Gene Atlas215010_s_atTestis4.9006.090Details
BioGPS Gene Atlas215010_s_atTestisGermCell4.9006.090Details
BioGPS Gene Atlas215010_s_atTestisIntersitial4.8006.090Details
BioGPS Gene Atlas215010_s_atTestisLeydigCell5.7506.090Details
BioGPS Gene Atlas215010_s_atTestisSeminiferousTubule5.0006.090Details
BioGPS Gene Atlas215010_s_atThalamus5.8506.090Details
BioGPS Gene Atlas215010_s_atThymus4.2006.090Details
BioGPS Gene Atlas215010_s_atThyroid7.1506.090Details
BioGPS Gene Atlas215010_s_atTongue5.6506.090Details
BioGPS Gene Atlas215010_s_atTonsil5.6006.090Details
BioGPS Gene Atlas215010_s_atTrachea4.8006.090Details
BioGPS Gene Atlas215010_s_atTrigeminalGanglion5.9006.090Details
BioGPS Gene Atlas215010_s_atUterus4.7006.090Details
BioGPS Gene Atlas215010_s_atUterusCorpus5.2006.090Details
BioGPS Gene Atlas215010_s_atWholeBlood6.2006.090Details
BioGPS Gene Atlas215010_s_atWholebrain6.5506.090Details
BioGPS Gene Atlas215010_s_atcolon5.6506.090Details
BioGPS Gene Atlas215010_s_atpineal_day7.4606.090Details
BioGPS Gene Atlas215010_s_atpineal_night7.5206.090Details
BioGPS Gene Atlas215010_s_atretina6.9006.090Details
BioGPS Gene Atlas215010_s_atsmall_intestine5.3006.090Details
BioGPS NCI60215010_s_at7865.6335.830Details
BioGPS NCI60215010_s_atA1725.1995.830Details
BioGPS NCI60215010_s_atA2045.4805.830Details
BioGPS NCI60215010_s_atA3615.5715.830Details
BioGPS NCI60215010_s_atA4985.4475.830Details
BioGPS NCI60215010_s_atA5495.6095.830Details
BioGPS NCI60215010_s_atACC35.8215.830Details
BioGPS NCI60215010_s_atACHN5.1645.830Details
BioGPS NCI60215010_s_atALVA315.9175.830Details
BioGPS NCI60215010_s_atCAKI15.6565.830Details
BioGPS NCI60215010_s_atCCRT CEM6.2285.830Details
BioGPS NCI60215010_s_atCOLO2055.4975.830Details
BioGPS NCI60215010_s_atDLD15.3605.830Details
BioGPS NCI60215010_s_atDU1455.0805.830Details
BioGPS NCI60215010_s_atEKVX5.3065.830Details
BioGPS NCI60215010_s_atGM1335.6285.830Details
BioGPS NCI60215010_s_atGM16005.7065.830Details
BioGPS NCI60215010_s_atGM23135.5775.830Details
BioGPS NCI60215010_s_atGM23455.4375.830Details
BioGPS NCI60215010_s_atGM24935.8565.830Details
BioGPS NCI60215010_s_atGM976.0015.830Details
BioGPS NCI60215010_s_atHCC29985.0225.830Details
BioGPS NCI60215010_s_atHCT1165.5245.830Details
BioGPS NCI60215010_s_atHCT155.1925.830Details
BioGPS NCI60215010_s_atHEK 293 T-rex5.6695.830Details
BioGPS NCI60215010_s_atHEK 293T5.5815.830Details
BioGPS NCI60215010_s_atHEK2935.4925.830Details
BioGPS NCI60215010_s_atHELA5.3865.830Details
BioGPS NCI60215010_s_atHEPG25.5175.830Details
BioGPS NCI60215010_s_atHL607.5005.830Details
BioGPS NCI60215010_s_atHOP625.5625.830Details
BioGPS NCI60215010_s_atHOP925.3085.830Details
BioGPS NCI60215010_s_atHS578T5.4275.830Details
BioGPS NCI60215010_s_atHSG7.3075.830Details
BioGPS NCI60215010_s_atHT10805.4615.830Details
BioGPS NCI60215010_s_atHT295.8395.830Details
BioGPS NCI60215010_s_atIGROV15.4635.830Details
BioGPS NCI60215010_s_atIOSE805.5585.830Details
BioGPS NCI60215010_s_atJURKAT5.5285.830Details
BioGPS NCI60215010_s_atK5625.8255.830Details
BioGPS NCI60215010_s_atKM125.6375.830Details
BioGPS NCI60215010_s_atLN185.1685.830Details
BioGPS NCI60215010_s_atLNCAP5.5195.830Details
BioGPS NCI60215010_s_atLOX IMVI5.4115.830Details
BioGPS NCI60215010_s_atM145.4635.830Details
BioGPS NCI60215010_s_atMALME 3M5.9135.830Details
BioGPS NCI60215010_s_atMCF75.2755.830Details
BioGPS NCI60215010_s_atMD MB2315.5675.830Details
BioGPS NCI60215010_s_atMDA MB4355.9595.830Details
BioGPS NCI60215010_s_atMOLT45.6395.830Details
BioGPS NCI60215010_s_atNCI 4605.6895.830Details
BioGPS NCI60215010_s_atNCI H22616.2975.830Details
BioGPS NCI60215010_s_atNCI H235.5585.830Details
BioGPS NCI60215010_s_atNCI H322M5.4375.830Details
BioGPS NCI60215010_s_atNCVADR RES5.4485.830Details
BioGPS NCI60215010_s_atOVCAR37.6145.830Details
BioGPS NCI60215010_s_atOVCAR45.5085.830Details
BioGPS NCI60215010_s_atOVCAR55.4815.830Details
BioGPS NCI60215010_s_atOVCAR86.4895.830Details
BioGPS NCI60215010_s_atPANC15.7355.830Details
BioGPS NCI60215010_s_atRL75.6375.830Details
BioGPS NCI60215010_s_atRPMI 82265.5715.830Details
BioGPS NCI60215010_s_atRS118465.8535.830Details
BioGPS NCI60215010_s_atRXF3935.4855.830Details
BioGPS NCI60215010_s_atSAOS25.5785.830Details
BioGPS NCI60215010_s_atSF2685.5245.830Details
BioGPS NCI60215010_s_atSF2955.4495.830Details
BioGPS NCI60215010_s_atSF5395.1635.830Details
BioGPS NCI60215010_s_atSHSYSY+RA8.7495.830Details
BioGPS NCI60215010_s_atSHSYSY-RA5.5115.830Details
BioGPS NCI60215010_s_atSKMEL25.5405.830Details
BioGPS NCI60215010_s_atSKMEL285.5365.830Details
BioGPS NCI60215010_s_atSKMEL55.4525.830Details
BioGPS NCI60215010_s_atSKOV35.6655.830Details
BioGPS NCI60215010_s_atSN12C5.4705.830Details
BioGPS NCI60215010_s_atSNB194.9635.830Details
BioGPS NCI60215010_s_atSNB755.4925.830Details
BioGPS NCI60215010_s_atSR5.6515.830Details
BioGPS NCI60215010_s_atSW6205.6115.830Details
BioGPS NCI60215010_s_atT245.6215.830Details
BioGPS NCI60215010_s_atT3M45.8895.830Details
BioGPS NCI60215010_s_atTK105.5245.830Details
BioGPS NCI60215010_s_atU1185.3075.830Details
BioGPS NCI60215010_s_atU1385.1765.830Details
BioGPS NCI60215010_s_atU20S5.2735.830Details
BioGPS NCI60215010_s_atU2515.5165.830Details
BioGPS NCI60215010_s_atU875.3245.830Details
BioGPS NCI60215010_s_atUACC2575.4145.830Details
BioGPS NCI60215010_s_atUACC625.9035.830Details
BioGPS NCI60215010_s_atUO315.2835.830Details
BioGPS NCI60215010_s_atZR75_15.7335.830Details
BioGPS NCI60215010_s_atastrocytes5.5055.830Details
BioGPS NCI60215010_s_athuh-75.6585.830Details