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Gene ID: 669 | BPGM Antibody Resource


BPGM Antibody Resource
Gene Full Name: 
2,3-bisphosphoglycerate mutase
Uniprot: 
P07738
Protein Name: 
bisphosphoglycerate mutase
Nucleotide: 
NM_199186
Alias: 
DPGM;
Ensembl: 
ENSG00000172331
Location: 
7q33
HPRD: 
01961
NCBI Gene: 
669
MIM: 
613896

Summary: 
2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]
Function: 
Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.1) and phosphatase (EC 3.1.3.13) activities.
Subcellular location: 
PTM: 
Acetylation;
Disease: 
Bisphosphoglycerate mutase deficiency (BPGMD) [MIM:222800]: A disease characterized by hemolytic anemia, splenomegaly, cholelithiasis and cholecystitis. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP58218_P050 BPGM antibody - C-terminal region (ARP58218_P050) Polyclonal Dog, Human, Mouse, Rat WB 50ug $289 Details
Polyclonal Antibody ARP58217_P050 BPGM antibody - middle region (ARP58217_P050) Polyclonal Dog, Human, Mouse, Pig, Rat, Zebrafish WB 50ug $289 Details
Protein OPPA02250 BPGM Human - Recombinant Human 2,3-Bisphosphoglycerate Mutase (5ug) 5ug $100 Details
Polyclonal Antibody OAAB05460 BPGM antibody - center region (OAAB05460) Human WB, ELISA 400ul $289 Details
Polyclonal Antibody OAAB08895 BPGM antibody - C - terminal region (OAAB08895) Human WB 400ul $289 Details
Polyclonal Antibody OAGA00560 BPGM antibody (OAGA00560) Polyclonal Human, Mouse ICC/IF, WB 100 ul $340 Details

Show all BPGM antibodies


Product Images
BPGM antibody - middle region (ARP58217_P050) in Human Heart cells using Western Blot

Sample Type: Human Heart

BPGM antibody - C-terminal region (ARP58218_P050) in Human Heart cells using Western Blot

Sample Type: Human Heart

BPGM antibody - C - terminal region (OAAB08895) in 293 cells using Western Blot

Sample Type: 293

BPGM antibody - C - terminal region (OAAB08895) in MDA-MB435 cells using Western Blot

Sample Type: MDA-MB435


BPGM Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP58217 African clawed frog BPGM antibody; Xenopus laevis BPGM antibody Q6GNS4 83.0%
ARP58217 Bovine BPGM antibody; Bos taurus BPGM antibody Q3T014 93.0%
ARP58218 Bovine BPGM antibody; Bos taurus BPGM antibody Q3T014 93.0%
ARP58218 Cat BPGM antibody; Felis catus BPGM antibody M3WX85 100.0%
ARP58217 Chicken BPGM antibody; Gallus gallus BPGM antibody Q5ZHV4 92.0%
ARP58218 Chicken BPGM antibody; Gallus gallus BPGM antibody Q5ZHV4 86.0%
ARP58218 Chimpanzee BPGM antibody; Pan troglodytes BPGM antibody K7DCT5 100.0%
ARP58218 Chimpanzee BPGM antibody; Pan troglodytes BPGM antibody H2QVE8 100.0%
ARP58217 Chimpanzee BPGM antibody; Pan troglodytes BPGM antibody K7DCT5 93.0%
ARP58217 Chimpanzee BPGM antibody; Pan troglodytes BPGM antibody H2QVE8 93.0%
ARP58217 Chinese softshell turtle BPGM antibody; Pelodiscus sinensis BPGM antibody K7FJS7 92.0%
ARP58218 Chinese softshell turtle BPGM antibody; Pelodiscus sinensis BPGM antibody K7FJS7 91.0%
ARP58218 Collared flycatcher BPGM antibody; Ficedula albicollis BPGM antibody U3K4M6 100.0%
ARP58217 Collared flycatcher BPGM antibody; Ficedula albicollis BPGM antibody U3K4M6 92.0%
ARP58218 Crab-eating macaque BPGM antibody; Macaca fascicularis BPGM antibody Q4R6L7 100.0%
ARP58217 Crab-eating macaque BPGM antibody; Macaca fascicularis BPGM antibody Q4R6L7 93.0%
ARP58217 Dog BPGM antibody; Canis familiaris BPGM antibody E2QYX1 93.0%
ARP58218 Dog BPGM antibody; Canis familiaris BPGM antibody E2QYX1 92.0%
ARP58217 Domestic duck BPGM antibody; Anas platyrhynchos BPGM antibody R0LRQ4 92.0%
ARP58218 Domestic duck BPGM antibody; Anas platyrhynchos BPGM antibody R0LRQ4 86.0%
ARP58218 Duckbill platypus BPGM antibody; Ornithorhynchus anatinus BPGM antibody F6U1J6 100.0%
ARP58217 Duckbill platypus BPGM antibody; Ornithorhynchus anatinus BPGM antibody F6U1J6 86.0%
ARP58218 European domestic ferret BPGM antibody; Mustela putorius furo BPGM antibody M3XYZ7 100.0%
ARP58217 European domestic ferret BPGM antibody; Mustela putorius furo BPGM antibody M3XYZ7 86.0%
ARP58218 Giant panda BPGM antibody; Ailuropoda melanoleuca BPGM antibody G1MCI3 100.0%
ARP58217 Giant panda BPGM antibody; Ailuropoda melanoleuca BPGM antibody G1MCI3 86.0%
ARP58217 Gray short-tailed opossum BPGM antibody; Monodelphis domestica BPGM antibody F6XLJ9 93.0%
ARP58218 Gray short-tailed opossum BPGM antibody; Monodelphis domestica BPGM antibody F6XLJ9 92.0%
ARP58218 Horse BPGM antibody; Equus caballus BPGM antibody F7CB51 100.0%
ARP58217 Horse BPGM antibody; Equus caballus BPGM antibody F7CB51 79.0%
ARP58217 Human BPGM antibody; Homo sapiens BPGM antibody P07738 100.0%
ARP58218 Human BPGM antibody; Homo sapiens BPGM antibody P07738 100.0%
ARP58218 Mouse BPGM antibody; Mus musculus BPGM antibody P15327 93.0%
ARP58218 Mouse BPGM antibody; Mus musculus BPGM antibody Q3TAQ8 93.0%
ARP58217 Mouse BPGM antibody; Mus musculus BPGM antibody D3Z223 79.0%
ARP58217 Mouse BPGM antibody; Mus musculus BPGM antibody P15327 79.0%
ARP58217 Mouse BPGM antibody; Mus musculus BPGM antibody Q3TAQ8 79.0%
ARP58218 Rabbit BPGM antibody; Oryctolagus cuniculus BPGM antibody P07952 100.0%
ARP58217 Rabbit BPGM antibody; Oryctolagus cuniculus BPGM antibody P07952 86.0%
ARP58217 Rat BPGM antibody; Rattus norvegicus BPGM antibody Q6P6G4 79.0%
ARP58218 Rat BPGM antibody; Rattus norvegicus BPGM antibody Q6P6G4 79.0%
ARP58217 Rat BPGM antibody; Rattus norvegicus BPGM antibody Q7TP58 79.0%
ARP58218 Rat BPGM antibody; Rattus norvegicus BPGM antibody Q7TP58 79.0%
ARP58218 Rhesus macaque BPGM antibody; Macaca mulatta BPGM antibody F6Q944 100.0%
ARP58217 Rhesus macaque BPGM antibody; Macaca mulatta BPGM antibody H9ER39 93.0%
ARP58218 Rhesus macaque BPGM antibody; Macaca mulatta BPGM antibody H9ER39 93.0%
ARP58217 Rhesus macaque BPGM antibody; Macaca mulatta BPGM antibody F6Q944 93.0%
ARP58218 Small-eared galago BPGM antibody; Otolemur garnettii BPGM antibody H0WPN3 100.0%
ARP58217 Small-eared galago BPGM antibody; Otolemur garnettii BPGM antibody H0WPN3 86.0%
ARP58217 Spotted green pufferfish BPGM antibody; Tetraodon nigroviridis BPGM antibody H3DEZ2 93.0%
ARP58217 Sumatran orangutan BPGM antibody; Pongo abelii BPGM antibody H2PNK3 93.0%
ARP58218 Sumatran orangutan BPGM antibody; Pongo abelii BPGM antibody H2PNK3 93.0%
ARP58218 Tasmanian devil BPGM antibody; Sarcophilus harrisii BPGM antibody G3W676 93.0%
ARP58217 Tasmanian devil BPGM antibody; Sarcophilus harrisii BPGM antibody G3W676 86.0%
ARP58218 Thirteen-lined ground squirrel BPGM antibody; Spermophilus tridecemlineatus BPGM antibody I3N8D1 100.0%
ARP58217 Thirteen-lined ground squirrel BPGM antibody; Spermophilus tridecemlineatus BPGM antibody I3N8D1 86.0%
ARP58218 Western clawed frog BPGM antibody; Xenopus tropicalis BPGM antibody Q28I68 90.0%
ARP58217 Western clawed frog BPGM antibody; Xenopus tropicalis BPGM antibody Q28I68 83.0%
ARP58218 White-tufted-ear marmoset BPGM antibody; Callithrix jacchus BPGM antibody F7IFM9 100.0%
ARP58217 White-tufted-ear marmoset BPGM antibody; Callithrix jacchus BPGM antibody F7IFM9 93.0%
ARP58218 Zebra finch BPGM antibody; Taeniopygia guttata BPGM antibody H0ZQC8 100.0%
ARP58217 Zebra finch BPGM antibody; Taeniopygia guttata BPGM antibody H0ZQC8 92.0%
ARP58217 Zebrafish BPGM antibody; Danio rerio BPGM antibody Q6DHM0 92.0%
ARP58217 Zebrafish BPGM antibody; Danio rerio BPGM antibody A8KBY7 92.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas203502_at721_B_lymphoblasts8.05028.180Details
BioGPS Gene Atlas203502_atAdipocyte6.65028.180Details
BioGPS Gene Atlas203502_atAdrenalCortex8.10028.180Details
BioGPS Gene Atlas203502_atAdrenalgland5.95028.180Details
BioGPS Gene Atlas203502_atAmygdala7.95028.180Details
BioGPS Gene Atlas203502_atAppendix7.80028.180Details
BioGPS Gene Atlas203502_atAtrioventricularNode7.10028.180Details
BioGPS Gene Atlas203502_atBDCA4+_DentriticCells7.25028.180Details
BioGPS Gene Atlas203502_atBonemarrow166.50028.180Details
BioGPS Gene Atlas203502_atBronchialEpithelialCells13.50028.180Details
BioGPS Gene Atlas203502_atCD105+_Endothelial42.15028.180Details
BioGPS Gene Atlas203502_atCD14+_Monocytes7.90028.180Details
BioGPS Gene Atlas203502_atCD19+_BCells(neg._sel.)8.45028.180Details
BioGPS Gene Atlas203502_atCD33+_Myeloid12.55028.180Details
BioGPS Gene Atlas203502_atCD34+8.30028.180Details
BioGPS Gene Atlas203502_atCD4+_Tcells7.55028.180Details
BioGPS Gene Atlas203502_atCD56+_NKCells13.85028.180Details
BioGPS Gene Atlas203502_atCD71+_EarlyErythroid691.45028.180Details
BioGPS Gene Atlas203502_atCD8+_Tcells6.55028.180Details
BioGPS Gene Atlas203502_atCardiacMyocytes13.20028.180Details
BioGPS Gene Atlas203502_atCaudatenucleus6.25028.180Details
BioGPS Gene Atlas203502_atCerebellum5.60028.180Details
BioGPS Gene Atlas203502_atCerebellumPeduncles8.10028.180Details
BioGPS Gene Atlas203502_atCiliaryGanglion6.65028.180Details
BioGPS Gene Atlas203502_atCingulateCortex9.75028.180Details
BioGPS Gene Atlas203502_atColorectaladenocarcinoma6.70028.180Details
BioGPS Gene Atlas203502_atDorsalRootGanglion6.05028.180Details
BioGPS Gene Atlas203502_atFetalThyroid6.80028.180Details
BioGPS Gene Atlas203502_atFetalbrain6.40028.180Details
BioGPS Gene Atlas203502_atFetalliver193.75028.180Details
BioGPS Gene Atlas203502_atFetallung26.90028.180Details
BioGPS Gene Atlas203502_atGlobusPallidus5.80028.180Details
BioGPS Gene Atlas203502_atHeart10.25028.180Details
BioGPS Gene Atlas203502_atHypothalamus11.75028.180Details
BioGPS Gene Atlas203502_atKidney6.55028.180Details
BioGPS Gene Atlas203502_atLeukemia_chronicMyelogenousK-5629.40028.180Details
BioGPS Gene Atlas203502_atLeukemia_promyelocytic-HL-605.85028.180Details
BioGPS Gene Atlas203502_atLeukemialymphoblastic(MOLT-4)7.70028.180Details
BioGPS Gene Atlas203502_atLiver9.60028.180Details
BioGPS Gene Atlas203502_atLung7.20028.180Details
BioGPS Gene Atlas203502_atLymphnode5.65028.180Details
BioGPS Gene Atlas203502_atLymphoma_burkitts(Daudi)8.65028.180Details
BioGPS Gene Atlas203502_atLymphoma_burkitts(Raji)10.15028.180Details
BioGPS Gene Atlas203502_atMedullaOblongata6.35028.180Details
BioGPS Gene Atlas203502_atOccipitalLobe6.15028.180Details
BioGPS Gene Atlas203502_atOlfactoryBulb5.50028.180Details
BioGPS Gene Atlas203502_atOvary4.60028.180Details
BioGPS Gene Atlas203502_atPancreas5.55028.180Details
BioGPS Gene Atlas203502_atPancreaticIslet7.25028.180Details
BioGPS Gene Atlas203502_atParietalLobe7.55028.180Details
BioGPS Gene Atlas203502_atPituitary8.90028.180Details
BioGPS Gene Atlas203502_atPlacenta628.90028.180Details
BioGPS Gene Atlas203502_atPons6.70028.180Details
BioGPS Gene Atlas203502_atPrefrontalCortex9.85028.180Details
BioGPS Gene Atlas203502_atProstate7.80028.180Details
BioGPS Gene Atlas203502_atSalivarygland6.10028.180Details
BioGPS Gene Atlas203502_atSkeletalMuscle11.00028.180Details
BioGPS Gene Atlas203502_atSkin5.95028.180Details
BioGPS Gene Atlas203502_atSmoothMuscle8.60028.180Details
BioGPS Gene Atlas203502_atSpinalcord8.20028.180Details
BioGPS Gene Atlas203502_atSubthalamicNucleus6.35028.180Details
BioGPS Gene Atlas203502_atSuperiorCervicalGanglion13.70028.180Details
BioGPS Gene Atlas203502_atTemporalLobe6.35028.180Details
BioGPS Gene Atlas203502_atTestis6.85028.180Details
BioGPS Gene Atlas203502_atTestisGermCell6.05028.180Details
BioGPS Gene Atlas203502_atTestisIntersitial5.90028.180Details
BioGPS Gene Atlas203502_atTestisLeydigCell7.05028.180Details
BioGPS Gene Atlas203502_atTestisSeminiferousTubule5.90028.180Details
BioGPS Gene Atlas203502_atThalamus7.50028.180Details
BioGPS Gene Atlas203502_atThymus5.25028.180Details
BioGPS Gene Atlas203502_atThyroid8.20028.180Details
BioGPS Gene Atlas203502_atTongue8.35028.180Details
BioGPS Gene Atlas203502_atTonsil6.80028.180Details
BioGPS Gene Atlas203502_atTrachea5.75028.180Details
BioGPS Gene Atlas203502_atTrigeminalGanglion9.70028.180Details
BioGPS Gene Atlas203502_atUterus5.55028.180Details
BioGPS Gene Atlas203502_atUterusCorpus7.25028.180Details
BioGPS Gene Atlas203502_atWholeBlood10.70028.180Details
BioGPS Gene Atlas203502_atWholebrain5.50028.180Details
BioGPS Gene Atlas203502_atcolon7.00028.180Details
BioGPS Gene Atlas203502_atpineal_day30.78028.180Details
BioGPS Gene Atlas203502_atpineal_night21.62028.180Details
BioGPS Gene Atlas203502_atretina9.42528.180Details
BioGPS Gene Atlas203502_atsmall_intestine6.75028.180Details
BioGPS NCI60203502_at78616.83121.710Details
BioGPS NCI60203502_atA17210.56321.710Details
BioGPS NCI60203502_atA2044.03621.710Details
BioGPS NCI60203502_atA3618.81121.710Details
BioGPS NCI60203502_atA49811.92721.710Details
BioGPS NCI60203502_atA54910.76721.710Details
BioGPS NCI60203502_atACC311.71821.710Details
BioGPS NCI60203502_atACHN6.31921.710Details
BioGPS NCI60203502_atALVA317.81721.710Details
BioGPS NCI60203502_atCAKI17.35921.710Details
BioGPS NCI60203502_atCCRT CEM6.15321.710Details
BioGPS NCI60203502_atCOLO2059.97221.710Details
BioGPS NCI60203502_atDLD15.39021.710Details
BioGPS NCI60203502_atDU1456.65621.710Details
BioGPS NCI60203502_atEKVX8.11821.710Details
BioGPS NCI60203502_atGM13311.73421.710Details
BioGPS NCI60203502_atGM160093.54221.710Details
BioGPS NCI60203502_atGM231385.93521.710Details
BioGPS NCI60203502_atGM234595.65221.710Details
BioGPS NCI60203502_atGM2493395.98721.710Details
BioGPS NCI60203502_atGM9711.20521.710Details
BioGPS NCI60203502_atHCC29984.97921.710Details
BioGPS NCI60203502_atHCT1166.86521.710Details
BioGPS NCI60203502_atHCT155.88121.710Details
BioGPS NCI60203502_atHEK 293 T-rex8.17521.710Details
BioGPS NCI60203502_atHEK 293T33.59921.710Details
BioGPS NCI60203502_atHEK29320.58221.710Details
BioGPS NCI60203502_atHELA6.62921.710Details
BioGPS NCI60203502_atHEPG24.04121.710Details
BioGPS NCI60203502_atHL605.47621.710Details
BioGPS NCI60203502_atHOP629.40321.710Details
BioGPS NCI60203502_atHOP9210.42721.710Details
BioGPS NCI60203502_atHS578T45.23121.710Details
BioGPS NCI60203502_atHSG6.73621.710Details
BioGPS NCI60203502_atHT10806.20521.710Details
BioGPS NCI60203502_atHT296.16921.710Details
BioGPS NCI60203502_atIGROV17.22721.710Details
BioGPS NCI60203502_atIOSE8011.60221.710Details
BioGPS NCI60203502_atJURKAT6.15921.710Details
BioGPS NCI60203502_atK5629.12521.710Details
BioGPS NCI60203502_atKM125.58121.710Details
BioGPS NCI60203502_atLN1814.39621.710Details
BioGPS NCI60203502_atLNCAP6.61921.710Details
BioGPS NCI60203502_atLOX IMVI5.25521.710Details
BioGPS NCI60203502_atM1423.88921.710Details
BioGPS NCI60203502_atMALME 3M7.87821.710Details
BioGPS NCI60203502_atMCF73.94321.710Details
BioGPS NCI60203502_atMD MB2316.23621.710Details
BioGPS NCI60203502_atMDA MB4359.80021.710Details
BioGPS NCI60203502_atMOLT411.36221.710Details
BioGPS NCI60203502_atNCI 46010.62821.710Details
BioGPS NCI60203502_atNCI H2267.22721.710Details
BioGPS NCI60203502_atNCI H237.29821.710Details
BioGPS NCI60203502_atNCI H322M5.27521.710Details
BioGPS NCI60203502_atNCVADR RES6.53421.710Details
BioGPS NCI60203502_atOVCAR35.41521.710Details
BioGPS NCI60203502_atOVCAR422.81921.710Details
BioGPS NCI60203502_atOVCAR54.00021.710Details
BioGPS NCI60203502_atOVCAR811.02921.710Details
BioGPS NCI60203502_atPANC112.05421.710Details
BioGPS NCI60203502_atRL77.77221.710Details
BioGPS NCI60203502_atRPMI 82265.96221.710Details
BioGPS NCI60203502_atRS118467.04721.710Details
BioGPS NCI60203502_atRXF3936.69621.710Details
BioGPS NCI60203502_atSAOS218.65721.710Details
BioGPS NCI60203502_atSF26812.04021.710Details
BioGPS NCI60203502_atSF29528.78821.710Details
BioGPS NCI60203502_atSF5396.39121.710Details
BioGPS NCI60203502_atSHSYSY+RA27.40121.710Details
BioGPS NCI60203502_atSHSYSY-RA31.31321.710Details
BioGPS NCI60203502_atSKMEL26.77221.710Details
BioGPS NCI60203502_atSKMEL2813.67321.710Details
BioGPS NCI60203502_atSKMEL57.14221.710Details
BioGPS NCI60203502_atSKOV37.33021.710Details
BioGPS NCI60203502_atSN12C6.11521.710Details
BioGPS NCI60203502_atSNB1938.19921.710Details
BioGPS NCI60203502_atSNB7526.94421.710Details
BioGPS NCI60203502_atSR11.47321.710Details
BioGPS NCI60203502_atSW6207.02021.710Details
BioGPS NCI60203502_atT246.60321.710Details
BioGPS NCI60203502_atT3M47.36321.710Details
BioGPS NCI60203502_atTK105.23621.710Details
BioGPS NCI60203502_atU11851.34921.710Details
BioGPS NCI60203502_atU138196.67021.710Details
BioGPS NCI60203502_atU20S5.73421.710Details
BioGPS NCI60203502_atU25118.93821.710Details
BioGPS NCI60203502_atU8739.89621.710Details
BioGPS NCI60203502_atUACC2575.19121.710Details
BioGPS NCI60203502_atUACC625.74821.710Details
BioGPS NCI60203502_atUO318.41521.710Details
BioGPS NCI60203502_atZR75_16.54221.710Details
BioGPS NCI60203502_atastrocytes31.03521.710Details
BioGPS NCI60203502_athuh-76.24221.710Details