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Gene ID: 660 | BMX Antibody Resource


BMX Antibody Resource
Gene Full Name: 
BMX non-receptor tyrosine kinase
Uniprot: 
P51813
Protein Name: 
cytoplasmic tyrosine-protein kinase BMX
Nucleotide: 
XM_005274580
Alias: 
ETK;PSCTK2;PSCTK3;
Ensembl: 
ENSG00000102010
Location: 
Xp22.2
HPRD: 
02111
NCBI Gene: 
660
MIM: 
300101

Summary: 
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009]
Function: 
Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility. Plays a critical role in TNF-induced angiogenesis, and implicated in the signaling of TEK and FLT1 receptors, 2 important receptor families essential for angiogenesis. Required for the phosphorylation and activation of STAT3, a transcription factor involved in cell differentiation. Also involved in interleukin-6 (IL6) induced differentiation. Plays also a role in programming adaptive cytoprotection against extracellular stress in different cell systems, salivary epithelial cells, brain endothelial cells, and dermal fibroblasts. May be involved in regulation of endocytosis through its interaction with an endosomal protein RUFY1. May also play a role in the growth and differentiation of hematopoietic cells; as well as in signal transduction in endocardial and arterial endothelial cells.
Subcellular location: 
Cytoplasm. Note: Localizes to the edges of spreading cells when complexed with BCAR1.
PTM: 
Phosphoprotein;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP48099_P050 BMX Antibody (ARP48099_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details
Polyclonal Antibody ARP48100_P050 BMX Antibody (ARP48100_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB17215 BMX antibody - center region (OAAB17215) Human; Mouse WB 400ul $289 Details
Polyclonal Antibody OAEC02343 BMX Antibody (OAEC02343) Human; Mouse WB, IHC, IF, ELISA 100ug $229 Details
Polyclonal Antibody OAAF00879 BMX Antibody (OAAF00879) Polyclonal Human, Mouse WB, IHC, ELISA 100 ug $229 Details
Polyclonal Antibody OAAF00942 BMX Antibody (OAAF00942) Polyclonal Human, Mouse WB, IHC, IF, ELISA 100 ug $229 Details
Polyclonal Antibody OAAF02297 BMX Antibody (OAAF02297) Polyclonal Human, Mouse WB, IHC, IF, ELISA 100 ug $229 Details

Show all BMX antibodies


Product Images
BMX antibody - center region (OAAB17215) in Mouse Heart cells using Western Blot

Sample Type: Mouse Heart

BMX Antibody (OAAF00879) in HepG2 cells using Western Blot

Sample Type: HepG2

BMX Antibody (OAAF00879) in Human skin cells using Immunohistochemistry

Sample Type: Human skin

BMX Antibody (OAAF00942) in A549 cells using Western Blot

Sample Type: A549

BMX Antibody (OAAF00942) in A549 cells using Immunofluorescence

Sample Type: A549

BMX Antibody (OAAF00942) in Human thyroid gland cells using Immunohistochemistry

Sample Type: Human thyroid gland

BMX Antibody (OAAF02297) in A549 cells using Immunofluorescence

Sample Type: A549

BMX Antibody (OAAF02297) in COS-7 cells using Western Blot

Sample Type: COS-7

BMX Antibody (OAAF02297) in Human thyroid gland cells using Immunohistochemistry

Sample Type: Human thyroid gland

BMX Antibody (OAEC02343) in COS-7 cells using Western Blot

Sample Type: COS-7

BMX Antibody (OAEC02343) in Human thyroid gland cells using Immunohistochemistry

Sample Type: Human thyroid gland


BMX Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP48100 Bovine BMX antibody; Bos taurus BMX antibody G3X680 100.0%
ARP48099 Bovine BMX antibody; Bos taurus BMX antibody G3X680 93.0%
ARP48100 Cat BMX antibody; Felis catus BMX antibody M3WDC9 100.0%
ARP48099 Cat BMX antibody; Felis catus BMX antibody M3WDC9 93.0%
ARP61617 Cat BMX antibody; Felis catus BMX antibody M3WDC9 83.0%
ARP48100 Chicken BMX antibody; Gallus gallus BMX antibody E1BTT3 79.0%
ARP48099 Chimpanzee BMX antibody; Pan troglodytes BMX antibody H2R0K8 100.0%
ARP48100 Chinese softshell turtle BMX antibody; Pelodiscus sinensis BMX antibody K7FFR0 79.0%
ARP48099 Dog BMX antibody; Canis familiaris BMX antibody E2RSP7 93.0%
ARP48100 Dog BMX antibody; Canis familiaris BMX antibody E2RSP7 93.0%
ARP48100 Domestic duck BMX antibody; Anas platyrhynchos BMX antibody U3J768 79.0%
ARP48100 Duckbill platypus BMX antibody; Ornithorhynchus anatinus BMX antibody F7F5Z2 93.0%
ARP48099 Duckbill platypus BMX antibody; Ornithorhynchus anatinus BMX antibody F7F5Z2 85.0%
ARP48100 European domestic ferret BMX antibody; Mustela putorius furo BMX antibody M3XU75 100.0%
ARP48099 European domestic ferret BMX antibody; Mustela putorius furo BMX antibody M3XU75 93.0%
ARP48099 Giant panda BMX antibody; Ailuropoda melanoleuca BMX antibody G1MBR3 93.0%
ARP48100 Gray short-tailed opossum BMX antibody; Monodelphis domestica BMX antibody F6WX83 86.0%
ARP48099 Gray short-tailed opossum BMX antibody; Monodelphis domestica BMX antibody F6WX83 85.0%
ARP48100 Horse BMX antibody; Equus caballus BMX antibody F6QHV9 100.0%
ARP48100 Horse BMX antibody; Equus caballus BMX antibody F6W8X2 100.0%
ARP48099 Horse BMX antibody; Equus caballus BMX antibody F6QHV9 93.0%
ARP48099 Horse BMX antibody; Equus caballus BMX antibody F6W8X2 93.0%
ARP48099 Human BMX antibody; Homo sapiens BMX antibody P51813 100.0%
ARP48100 Human BMX antibody; Homo sapiens BMX antibody P51813 100.0%
ARP72619 Human BMX antibody; Homo sapiens BMX antibody P51813 100.0%
ARP48100 Mouse BMX antibody; Mus musculus BMX antibody P97504 100.0%
ARP48100 Mouse BMX antibody; Mus musculus BMX antibody Q8BNW5 100.0%
ARP48100 Mouse BMX antibody; Mus musculus BMX antibody B1AUL5 100.0%
ARP48100 Mouse BMX antibody; Mus musculus BMX antibody B1AUL6 100.0%
ARP48099 Mouse BMX antibody; Mus musculus BMX antibody P97504 93.0%
ARP48099 Mouse BMX antibody; Mus musculus BMX antibody B1AUL5 93.0%
ARP48099 Mouse BMX antibody; Mus musculus BMX antibody B1AUL6 93.0%
ARP48099 Northern white-cheeked gibbon BMX antibody; Nomascus leucogenys BMX antibody G1RE09 100.0%
ARP48100 Northern white-cheeked gibbon BMX antibody; Nomascus leucogenys BMX antibody G1RE09 100.0%
ARP72619 Northern white-cheeked gibbon BMX antibody; Nomascus leucogenys BMX antibody G1RE09 100.0%
ARP48100 Pig BMX antibody; Sus scrofa BMX antibody F1SQT2 100.0%
ARP48100 Pig BMX antibody; Sus scrofa BMX antibody K7GSA0 100.0%
ARP48099 Pig BMX antibody; Sus scrofa BMX antibody F1SQT2 93.0%
ARP48100 Rabbit BMX antibody; Oryctolagus cuniculus BMX antibody G1TEE9 100.0%
ARP48099 Rabbit BMX antibody; Oryctolagus cuniculus BMX antibody G1TEE9 93.0%
ARP48099 Rat BMX antibody; Rattus norvegicus BMX antibody F1LVI0 93.0%
ARP48100 Rat BMX antibody; Rattus norvegicus BMX antibody F1LVI0 93.0%
ARP48099 Rhesus macaque BMX antibody; Macaca mulatta BMX antibody F7AH50 100.0%
ARP48100 Rhesus macaque BMX antibody; Macaca mulatta BMX antibody F7AH50 100.0%
ARP72619 Rhesus macaque BMX antibody; Macaca mulatta BMX antibody F7AH50 86.0%
ARP48100 Small-eared galago BMX antibody; Otolemur garnettii BMX antibody H0WMI3 100.0%
ARP48099 Small-eared galago BMX antibody; Otolemur garnettii BMX antibody H0WMI3 93.0%
ARP48099 Sumatran orangutan BMX antibody; Pongo abelii BMX antibody H2PUZ4 100.0%
ARP48100 Sumatran orangutan BMX antibody; Pongo abelii BMX antibody H2PUZ4 100.0%
ARP72619 Sumatran orangutan BMX antibody; Pongo abelii BMX antibody H2PUZ4 100.0%
ARP48099 Tasmanian devil BMX antibody; Sarcophilus harrisii BMX antibody G3VBH4 85.0%
ARP48099 Tasmanian devil BMX antibody; Sarcophilus harrisii BMX antibody G3VBH5 85.0%
ARP48100 Tasmanian devil BMX antibody; Sarcophilus harrisii BMX antibody G3VBH4 79.0%
ARP48100 Tasmanian devil BMX antibody; Sarcophilus harrisii BMX antibody G3VBH5 79.0%
ARP48099 Thirteen-lined ground squirrel BMX antibody; Spermophilus tridecemlineatus BMX antibody I3M858 86.0%
ARP48099 White-tufted-ear marmoset BMX antibody; Callithrix jacchus BMX antibody F6SSK9 100.0%
ARP48100 White-tufted-ear marmoset BMX antibody; Callithrix jacchus BMX antibody F6SSK9 100.0%
ARP48099 White-tufted-ear marmoset BMX antibody; Callithrix jacchus BMX antibody F6XJR9 100.0%
ARP48100 White-tufted-ear marmoset BMX antibody; Callithrix jacchus BMX antibody F6XJR9 100.0%
ARP72619 White-tufted-ear marmoset BMX antibody; Callithrix jacchus BMX antibody F6SSK9 79.0%
ARP72619 White-tufted-ear marmoset BMX antibody; Callithrix jacchus BMX antibody F6XJR9 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas206464_at721_B_lymphoblasts5.5504.770Details
BioGPS Gene Atlas206464_atAdipocyte4.4504.770Details
BioGPS Gene Atlas206464_atAdrenalCortex4.9004.770Details
BioGPS Gene Atlas206464_atAdrenalgland3.8004.770Details
BioGPS Gene Atlas206464_atAmygdala4.6504.770Details
BioGPS Gene Atlas206464_atAppendix4.8504.770Details
BioGPS Gene Atlas206464_atAtrioventricularNode3.4504.770Details
BioGPS Gene Atlas206464_atBDCA4+_DentriticCells4.7504.770Details
BioGPS Gene Atlas206464_atBonemarrow8.8004.770Details
BioGPS Gene Atlas206464_atBronchialEpithelialCells4.4504.770Details
BioGPS Gene Atlas206464_atCD105+_Endothelial4.5004.770Details
BioGPS Gene Atlas206464_atCD14+_Monocytes4.8004.770Details
BioGPS Gene Atlas206464_atCD19+_BCells(neg._sel.)4.8004.770Details
BioGPS Gene Atlas206464_atCD33+_Myeloid5.7504.770Details
BioGPS Gene Atlas206464_atCD34+5.6004.770Details
BioGPS Gene Atlas206464_atCD4+_Tcells4.7504.770Details
BioGPS Gene Atlas206464_atCD56+_NKCells5.3504.770Details
BioGPS Gene Atlas206464_atCD71+_EarlyErythroid4.2004.770Details
BioGPS Gene Atlas206464_atCD8+_Tcells4.2504.770Details
BioGPS Gene Atlas206464_atCardiacMyocytes5.7004.770Details
BioGPS Gene Atlas206464_atCaudatenucleus4.0004.770Details
BioGPS Gene Atlas206464_atCerebellum3.6504.770Details
BioGPS Gene Atlas206464_atCerebellumPeduncles5.1004.770Details
BioGPS Gene Atlas206464_atCiliaryGanglion3.2004.770Details
BioGPS Gene Atlas206464_atCingulateCortex4.6004.770Details
BioGPS Gene Atlas206464_atColorectaladenocarcinoma4.5004.770Details
BioGPS Gene Atlas206464_atDorsalRootGanglion4.0004.770Details
BioGPS Gene Atlas206464_atFetalThyroid4.4004.770Details
BioGPS Gene Atlas206464_atFetalbrain4.4504.770Details
BioGPS Gene Atlas206464_atFetalliver3.9004.770Details
BioGPS Gene Atlas206464_atFetallung3.7004.770Details
BioGPS Gene Atlas206464_atGlobusPallidus3.3004.770Details
BioGPS Gene Atlas206464_atHeart5.7504.770Details
BioGPS Gene Atlas206464_atHypothalamus4.9004.770Details
BioGPS Gene Atlas206464_atKidney3.7004.770Details
BioGPS Gene Atlas206464_atLeukemia_chronicMyelogenousK-5624.0504.770Details
BioGPS Gene Atlas206464_atLeukemia_promyelocytic-HL-603.9504.770Details
BioGPS Gene Atlas206464_atLeukemialymphoblastic(MOLT-4)3.6504.770Details
BioGPS Gene Atlas206464_atLiver5.9004.770Details
BioGPS Gene Atlas206464_atLung5.0504.770Details
BioGPS Gene Atlas206464_atLymphnode4.8504.770Details
BioGPS Gene Atlas206464_atLymphoma_burkitts(Daudi)5.7504.770Details
BioGPS Gene Atlas206464_atLymphoma_burkitts(Raji)6.3004.770Details
BioGPS Gene Atlas206464_atMedullaOblongata4.2504.770Details
BioGPS Gene Atlas206464_atOccipitalLobe4.0504.770Details
BioGPS Gene Atlas206464_atOlfactoryBulb3.6504.770Details
BioGPS Gene Atlas206464_atOvary3.0004.770Details
BioGPS Gene Atlas206464_atPancreas3.6504.770Details
BioGPS Gene Atlas206464_atPancreaticIslet5.7004.770Details
BioGPS Gene Atlas206464_atParietalLobe4.7504.770Details
BioGPS Gene Atlas206464_atPituitary5.2004.770Details
BioGPS Gene Atlas206464_atPlacenta4.7004.770Details
BioGPS Gene Atlas206464_atPons4.3004.770Details
BioGPS Gene Atlas206464_atPrefrontalCortex5.5504.770Details
BioGPS Gene Atlas206464_atProstate5.3004.770Details
BioGPS Gene Atlas206464_atSalivarygland3.6004.770Details
BioGPS Gene Atlas206464_atSkeletalMuscle7.7504.770Details
BioGPS Gene Atlas206464_atSkin3.4504.770Details
BioGPS Gene Atlas206464_atSmoothMuscle5.1004.770Details
BioGPS Gene Atlas206464_atSpinalcord4.8004.770Details
BioGPS Gene Atlas206464_atSubthalamicNucleus4.1004.770Details
BioGPS Gene Atlas206464_atSuperiorCervicalGanglion5.6504.770Details
BioGPS Gene Atlas206464_atTemporalLobe4.1004.770Details
BioGPS Gene Atlas206464_atTestis3.8504.770Details
BioGPS Gene Atlas206464_atTestisGermCell3.7504.770Details
BioGPS Gene Atlas206464_atTestisIntersitial3.8004.770Details
BioGPS Gene Atlas206464_atTestisLeydigCell5.5504.770Details
BioGPS Gene Atlas206464_atTestisSeminiferousTubule3.8504.770Details
BioGPS Gene Atlas206464_atThalamus4.7504.770Details
BioGPS Gene Atlas206464_atThymus3.5504.770Details
BioGPS Gene Atlas206464_atThyroid5.6504.770Details
BioGPS Gene Atlas206464_atTongue4.4004.770Details
BioGPS Gene Atlas206464_atTonsil4.3504.770Details
BioGPS Gene Atlas206464_atTrachea3.7504.770Details
BioGPS Gene Atlas206464_atTrigeminalGanglion4.5004.770Details
BioGPS Gene Atlas206464_atUterus3.7004.770Details
BioGPS Gene Atlas206464_atUterusCorpus6.4004.770Details
BioGPS Gene Atlas206464_atWholeBlood12.4504.770Details
BioGPS Gene Atlas206464_atWholebrain3.8004.770Details
BioGPS Gene Atlas206464_atcolon4.5004.770Details
BioGPS Gene Atlas206464_atpineal_day5.5804.770Details
BioGPS Gene Atlas206464_atpineal_night5.4204.770Details
BioGPS Gene Atlas206464_atretina5.4254.770Details
BioGPS Gene Atlas206464_atsmall_intestine4.3004.770Details
BioGPS NCI60206464_at7864.03518.570Details
BioGPS NCI60206464_atA1723.82118.570Details
BioGPS NCI60206464_atA2044.00318.570Details
BioGPS NCI60206464_atA3613.98018.570Details
BioGPS NCI60206464_atA4983.95718.570Details
BioGPS NCI60206464_atA5494.00318.570Details
BioGPS NCI60206464_atACC34.07418.570Details
BioGPS NCI60206464_atACHN3.79018.570Details
BioGPS NCI60206464_atALVA314.23618.570Details
BioGPS NCI60206464_atCAKI14.04718.570Details
BioGPS NCI60206464_atCCRT CEM4.33818.570Details
BioGPS NCI60206464_atCOLO2053.92918.570Details
BioGPS NCI60206464_atDLD13.91018.570Details
BioGPS NCI60206464_atDU1453.82018.570Details
BioGPS NCI60206464_atEKVX3.80518.570Details
BioGPS NCI60206464_atGM1334.04718.570Details
BioGPS NCI60206464_atGM16004.10518.570Details
BioGPS NCI60206464_atGM23133.97918.570Details
BioGPS NCI60206464_atGM23453.95918.570Details
BioGPS NCI60206464_atGM24934.09818.570Details
BioGPS NCI60206464_atGM974.28818.570Details
BioGPS NCI60206464_atHCC29983.78618.570Details
BioGPS NCI60206464_atHCT1163.93518.570Details
BioGPS NCI60206464_atHCT153.74318.570Details
BioGPS NCI60206464_atHEK 293 T-rex4.00018.570Details
BioGPS NCI60206464_atHEK 293T3.92018.570Details
BioGPS NCI60206464_atHEK2933.94518.570Details
BioGPS NCI60206464_atHELA3.72018.570Details
BioGPS NCI60206464_atHEPG23.93818.570Details
BioGPS NCI60206464_atHL603.99318.570Details
BioGPS NCI60206464_atHOP623.93118.570Details
BioGPS NCI60206464_atHOP923.82618.570Details
BioGPS NCI60206464_atHS578T3.88118.570Details
BioGPS NCI60206464_atHSG3.87718.570Details
BioGPS NCI60206464_atHT10803.93718.570Details
BioGPS NCI60206464_atHT294.07518.570Details
BioGPS NCI60206464_atIGROV13.92318.570Details
BioGPS NCI60206464_atIOSE803.89518.570Details
BioGPS NCI60206464_atJURKAT3.94818.570Details
BioGPS NCI60206464_atK5624.18018.570Details
BioGPS NCI60206464_atKM124.07718.570Details
BioGPS NCI60206464_atLN183.79618.570Details
BioGPS NCI60206464_atLNCAP10.33418.570Details
BioGPS NCI60206464_atLOX IMVI3.94618.570Details
BioGPS NCI60206464_atM143.90918.570Details
BioGPS NCI60206464_atMALME 3M4.13218.570Details
BioGPS NCI60206464_atMCF73.80918.570Details
BioGPS NCI60206464_atMD MB2313.97118.570Details
BioGPS NCI60206464_atMDA MB4354.10818.570Details
BioGPS NCI60206464_atMOLT44.03518.570Details
BioGPS NCI60206464_atNCI 4604.02518.570Details
BioGPS NCI60206464_atNCI H2264.02618.570Details
BioGPS NCI60206464_atNCI H233.93918.570Details
BioGPS NCI60206464_atNCI H322M3.96418.570Details
BioGPS NCI60206464_atNCVADR RES3.80918.570Details
BioGPS NCI60206464_atOVCAR34.09318.570Details
BioGPS NCI60206464_atOVCAR43.93918.570Details
BioGPS NCI60206464_atOVCAR53.90718.570Details
BioGPS NCI60206464_atOVCAR83.81218.570Details
BioGPS NCI60206464_atPANC13.99618.570Details
BioGPS NCI60206464_atRL74.00318.570Details
BioGPS NCI60206464_atRPMI 82263.98918.570Details
BioGPS NCI60206464_atRS118464.07918.570Details
BioGPS NCI60206464_atRXF3933.89818.570Details
BioGPS NCI60206464_atSAOS23.98118.570Details
BioGPS NCI60206464_atSF2683.92418.570Details
BioGPS NCI60206464_atSF2954.20418.570Details
BioGPS NCI60206464_atSF5393.73818.570Details
BioGPS NCI60206464_atSHSYSY+RA3.82218.570Details
BioGPS NCI60206464_atSHSYSY-RA3.88218.570Details
BioGPS NCI60206464_atSKMEL21574.75318.570Details
BioGPS NCI60206464_atSKMEL283.93618.570Details
BioGPS NCI60206464_atSKMEL53.81018.570Details
BioGPS NCI60206464_atSKOV33.99318.570Details
BioGPS NCI60206464_atSN12C3.87618.570Details
BioGPS NCI60206464_atSNB193.82118.570Details
BioGPS NCI60206464_atSNB753.94118.570Details
BioGPS NCI60206464_atSR3.99418.570Details
BioGPS NCI60206464_atSW6203.96618.570Details
BioGPS NCI60206464_atT244.03218.570Details
BioGPS NCI60206464_atT3M44.07918.570Details
BioGPS NCI60206464_atTK103.93218.570Details
BioGPS NCI60206464_atU1183.91218.570Details
BioGPS NCI60206464_atU1383.80418.570Details
BioGPS NCI60206464_atU20S4.51718.570Details
BioGPS NCI60206464_atU2513.93418.570Details
BioGPS NCI60206464_atU873.84018.570Details
BioGPS NCI60206464_atUACC2573.92018.570Details
BioGPS NCI60206464_atUACC623.98118.570Details
BioGPS NCI60206464_atUO313.87118.570Details
BioGPS NCI60206464_atZR75_14.02918.570Details
BioGPS NCI60206464_atastrocytes4.04218.570Details
BioGPS NCI60206464_athuh-74.04018.570Details