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Gene ID: 658 | BMPR1B Antibody Resource


BMPR1B Antibody Resource
Gene Full Name: 
bone morphogenetic protein receptor, type IB
Uniprot: 
O00238
Protein Name: 
bone morphogenetic protein receptor type-1B
Nucleotide: 
NM_001203
Alias: 
ALK6;ALK-6;CDw293;
Ensembl: 
ENSG00000138696
Location: 
4q22-q24
HPRD: 
04457
NCBI Gene: 
658
MIM: 
603248

Summary: 
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Function: 
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5.
Subcellular location: 
Membrane; Single-pass type I membrane protein.
PTM: 
Disulfide bond;
Disease: 
Acromesomelic chondrodysplasia, with genital anomalies (AMDGA) [MIM:609441]: A form of chondrodysplasia. Acromesomelic chondrodysplasias are rare hereditary skeletal disorders characterized by short stature, very short limbs and hand/foot malformations. The severity of limb abnormalities increases from proximal to distal with profoundly affected hands and feet showing brachydactyly and/or rudimentary fingers (knob-like fingers). Note: The disease is caused by mutations affecting the gene represented in this entry. Brachydactyly A2 (BDA2) [MIM:112600]: A form of brachydactyly. Brachydactyly defines a group of inherited malformations characterized by shortening of the digits due to abnormal development of the phalanges and/or the metacarpals. In brachydactyly type A2 shortening of the middle phalanges is confined to the index finger and the second toe, all other digits being more or less normal. Because of a rhomboid or triangular shape of the affected middle phalanx, the end of the second finger usually deviates radially. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP32131_P050 BMPR1B Antibody (ARP32131_P050) Polyclonal Bovine, Dog, Goat, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Sheep Not tested 50 ug $50 Details
Polyclonal Antibody OAAB08279 BMPR1B antibody - center region (OAAB08279) Human WB, IHC 400ul $289 Details
Polyclonal Antibody OAAB11665 Mouse Bmpr1b antibody - center region (OAAB11665) Human WB 400ul $289 Details
Polyclonal Antibody OAAB15466 BMPR1B antibody (N - terminal region K15) (OAAB15466) Human; Mouse WB 400ul $289 Details
Polyclonal Antibody OAAB15467 BMPR1B antibody - C - terminal region (OAAB15467) Human WB 400ul $289 Details
Polyclonal Antibody OAAB15468 BMPR1B antibody (N - terminal region D17) (OAAB15468) Human WB 400ul $289 Details

Show all BMPR1B antibodies


Product Images
BMPR1B antibody - center region (OAAB08279) in Human Brain cells using Immunohistochemistry

Sample Type: Human Brain

BMPR1B antibody - center region (OAAB08279) in U251 cells using Western Blot

Sample Type: U251

Mouse Bmpr1b antibody - center region (OAAB11665) in Hela cells using Western Blot

Sample Type: Hela

BMPR1B antibody (N - terminal region (OAAB15466) in NCI-H460 cells using Western Blot

Sample Type: NCI-H460

BMPR1B antibody - C - terminal region (OAAB15467) in NCI-H460 cells using Western Blot

Sample Type: NCI-H460

BMPR1B antibody (N - terminal region (OAAB15468) in NCI-H460 cells using Western Blot

Sample Type: NCI-H460


BMPR1B Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP32131 African elephant BMPR1B antibody; Loxodonta africana BMPR1B antibody G3T672 93.0%
ARP32131 Bovine BMPR1B antibody; Bos taurus BMPR1B antibody A7YWG6 93.0%
ARP32131 Cat BMPR1B antibody; Felis catus BMPR1B antibody M3XFJ2 100.0%
ARP32131 Chimpanzee BMPR1B antibody; Pan troglodytes BMPR1B antibody H2QPW8 100.0%
ARP32131 Dog BMPR1B antibody; Canis familiaris BMPR1B antibody E2RA74 100.0%
ARP32131 European domestic ferret BMPR1B antibody; Mustela putorius furo BMPR1B antibody M3XSM6 100.0%
ARP32131 Giant panda BMPR1B antibody; Ailuropoda melanoleuca BMPR1B antibody G1LH84 100.0%
ARP32131 Goat BMPR1B antibody; Capra hircus BMPR1B antibody K7TGV0 93.0%
ARP32131 Horse BMPR1B antibody; Equus caballus BMPR1B antibody F6SYZ2 100.0%
ARP32131 Human BMPR1B antibody; Homo sapiens BMPR1B antibody O00238 100.0%
ARP32131 Human BMPR1B antibody; Homo sapiens BMPR1B antibody D6RAW8 100.0%
ARP32131 Human BMPR1B antibody; Homo sapiens BMPR1B antibody D6RGW8 100.0%
ARP32131 Human BMPR1B antibody; Homo sapiens BMPR1B antibody O00238-2 100.0%
ARP32131 Mouse BMPR1B antibody; Mus musculus BMPR1B antibody P36898 100.0%
ARP32131 Mouse BMPR1B antibody; Mus musculus BMPR1B antibody B2RRZ4 100.0%
ARP32131 Mouse BMPR1B antibody; Mus musculus BMPR1B antibody D6RET5 100.0%
ARP32131 Northern white-cheeked gibbon BMPR1B antibody; Nomascus leucogenys BMPR1B antibody G1RVB7 100.0%
ARP32131 Northern white-cheeked gibbon BMPR1B antibody; Nomascus leucogenys BMPR1B antibody G1RVC0 100.0%
ARP32131 Pig BMPR1B antibody; Sus scrofa BMPR1B antibody I3LIC3 100.0%
ARP32131 Pig BMPR1B antibody; Sus scrofa BMPR1B antibody K7GQX2 100.0%
ARP32131 Rabbit BMPR1B antibody; Oryctolagus cuniculus BMPR1B antibody G1T8L9 100.0%
ARP32131 Rhesus macaque BMPR1B antibody; Macaca mulatta BMPR1B antibody F7HJS7 100.0%
ARP32131 Small-eared galago BMPR1B antibody; Otolemur garnettii BMPR1B antibody H0WM21 100.0%
ARP32131 Sumatran orangutan BMPR1B antibody; Pongo abelii BMPR1B antibody H2PDX5 100.0%
ARP32131 White-tufted-ear marmoset BMPR1B antibody; Callithrix jacchus BMPR1B antibody F6REH8 93.0%
ARP32131 White-tufted-ear marmoset BMPR1B antibody; Callithrix jacchus BMPR1B antibody F6RPX2 93.0%
ARP32131 White-tufted-ear marmoset BMPR1B antibody; Callithrix jacchus BMPR1B antibody F6S184 93.0%
ARP32131 White-tufted-ear marmoset BMPR1B antibody; Callithrix jacchus BMPR1B antibody F7IS54 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas210523_at721_B_lymphoblasts5.3005.720Details
BioGPS Gene Atlas210523_atAdipocyte4.3005.720Details
BioGPS Gene Atlas210523_atAdrenalCortex5.8505.720Details
BioGPS Gene Atlas210523_atAdrenalgland3.7505.720Details
BioGPS Gene Atlas210523_atAmygdala4.5005.720Details
BioGPS Gene Atlas210523_atAppendix13.0005.720Details
BioGPS Gene Atlas210523_atAtrioventricularNode3.5505.720Details
BioGPS Gene Atlas210523_atBDCA4+_DentriticCells4.4005.720Details
BioGPS Gene Atlas210523_atBonemarrow5.8005.720Details
BioGPS Gene Atlas210523_atBronchialEpithelialCells4.6005.720Details
BioGPS Gene Atlas210523_atCD105+_Endothelial4.3005.720Details
BioGPS Gene Atlas210523_atCD14+_Monocytes4.5005.720Details
BioGPS Gene Atlas210523_atCD19+_BCells(neg._sel.)4.5505.720Details
BioGPS Gene Atlas210523_atCD33+_Myeloid5.3005.720Details
BioGPS Gene Atlas210523_atCD34+5.1005.720Details
BioGPS Gene Atlas210523_atCD4+_Tcells4.4505.720Details
BioGPS Gene Atlas210523_atCD56+_NKCells5.1005.720Details
BioGPS Gene Atlas210523_atCD71+_EarlyErythroid4.1005.720Details
BioGPS Gene Atlas210523_atCD8+_Tcells4.0005.720Details
BioGPS Gene Atlas210523_atCardiacMyocytes5.9005.720Details
BioGPS Gene Atlas210523_atCaudatenucleus4.4505.720Details
BioGPS Gene Atlas210523_atCerebellum7.6005.720Details
BioGPS Gene Atlas210523_atCerebellumPeduncles4.9005.720Details
BioGPS Gene Atlas210523_atCiliaryGanglion5.0005.720Details
BioGPS Gene Atlas210523_atCingulateCortex4.4505.720Details
BioGPS Gene Atlas210523_atColorectaladenocarcinoma4.3005.720Details
BioGPS Gene Atlas210523_atDorsalRootGanglion4.6005.720Details
BioGPS Gene Atlas210523_atFetalThyroid4.2005.720Details
BioGPS Gene Atlas210523_atFetalbrain4.3505.720Details
BioGPS Gene Atlas210523_atFetalliver3.8005.720Details
BioGPS Gene Atlas210523_atFetallung3.5505.720Details
BioGPS Gene Atlas210523_atGlobusPallidus3.7005.720Details
BioGPS Gene Atlas210523_atHeart10.6005.720Details
BioGPS Gene Atlas210523_atHypothalamus4.6005.720Details
BioGPS Gene Atlas210523_atKidney4.1005.720Details
BioGPS Gene Atlas210523_atLeukemia_chronicMyelogenousK-5623.9505.720Details
BioGPS Gene Atlas210523_atLeukemia_promyelocytic-HL-604.4505.720Details
BioGPS Gene Atlas210523_atLeukemialymphoblastic(MOLT-4)3.5005.720Details
BioGPS Gene Atlas210523_atLiver5.9005.720Details
BioGPS Gene Atlas210523_atLung4.7505.720Details
BioGPS Gene Atlas210523_atLymphnode3.7505.720Details
BioGPS Gene Atlas210523_atLymphoma_burkitts(Daudi)5.5005.720Details
BioGPS Gene Atlas210523_atLymphoma_burkitts(Raji)6.3505.720Details
BioGPS Gene Atlas210523_atMedullaOblongata6.4005.720Details
BioGPS Gene Atlas210523_atOccipitalLobe3.9005.720Details
BioGPS Gene Atlas210523_atOlfactoryBulb3.4505.720Details
BioGPS Gene Atlas210523_atOvary2.9005.720Details
BioGPS Gene Atlas210523_atPancreas3.5005.720Details
BioGPS Gene Atlas210523_atPancreaticIslet4.6005.720Details
BioGPS Gene Atlas210523_atParietalLobe7.0005.720Details
BioGPS Gene Atlas210523_atPituitary7.1005.720Details
BioGPS Gene Atlas210523_atPlacenta4.4505.720Details
BioGPS Gene Atlas210523_atPons4.9005.720Details
BioGPS Gene Atlas210523_atPrefrontalCortex5.3505.720Details
BioGPS Gene Atlas210523_atProstate5.0505.720Details
BioGPS Gene Atlas210523_atSalivarygland4.8505.720Details
BioGPS Gene Atlas210523_atSkeletalMuscle53.7505.720Details
BioGPS Gene Atlas210523_atSkin5.3505.720Details
BioGPS Gene Atlas210523_atSmoothMuscle4.7005.720Details
BioGPS Gene Atlas210523_atSpinalcord4.6505.720Details
BioGPS Gene Atlas210523_atSubthalamicNucleus4.0005.720Details
BioGPS Gene Atlas210523_atSuperiorCervicalGanglion19.2505.720Details
BioGPS Gene Atlas210523_atTemporalLobe4.4005.720Details
BioGPS Gene Atlas210523_atTestis4.2505.720Details
BioGPS Gene Atlas210523_atTestisGermCell3.6005.720Details
BioGPS Gene Atlas210523_atTestisIntersitial3.9505.720Details
BioGPS Gene Atlas210523_atTestisLeydigCell4.3505.720Details
BioGPS Gene Atlas210523_atTestisSeminiferousTubule3.7505.720Details
BioGPS Gene Atlas210523_atThalamus4.4005.720Details
BioGPS Gene Atlas210523_atThymus3.4505.720Details
BioGPS Gene Atlas210523_atThyroid5.4005.720Details
BioGPS Gene Atlas210523_atTongue4.7005.720Details
BioGPS Gene Atlas210523_atTonsil4.8505.720Details
BioGPS Gene Atlas210523_atTrachea4.6505.720Details
BioGPS Gene Atlas210523_atTrigeminalGanglion4.8505.720Details
BioGPS Gene Atlas210523_atUterus3.5505.720Details
BioGPS Gene Atlas210523_atUterusCorpus20.3505.720Details
BioGPS Gene Atlas210523_atWholeBlood4.7505.720Details
BioGPS Gene Atlas210523_atWholebrain3.7005.720Details
BioGPS Gene Atlas210523_atcolon4.4005.720Details
BioGPS Gene Atlas210523_atpineal_day5.2405.720Details
BioGPS Gene Atlas210523_atpineal_night5.1605.720Details
BioGPS Gene Atlas210523_atretina5.0755.720Details
BioGPS Gene Atlas210523_atsmall_intestine4.2005.720Details
BioGPS NCI60210523_at7864.5414.660Details
BioGPS NCI60210523_atA1724.2604.660Details
BioGPS NCI60210523_atA2044.4114.660Details
BioGPS NCI60210523_atA3614.4964.660Details
BioGPS NCI60210523_atA4984.4474.660Details
BioGPS NCI60210523_atA5494.5324.660Details
BioGPS NCI60210523_atACC34.6274.660Details
BioGPS NCI60210523_atACHN4.1974.660Details
BioGPS NCI60210523_atALVA314.7124.660Details
BioGPS NCI60210523_atCAKI14.5914.660Details
BioGPS NCI60210523_atCCRT CEM17.7104.660Details
BioGPS NCI60210523_atCOLO2054.4764.660Details
BioGPS NCI60210523_atDLD14.4264.660Details
BioGPS NCI60210523_atDU1454.2814.660Details
BioGPS NCI60210523_atEKVX4.3244.660Details
BioGPS NCI60210523_atGM1334.5504.660Details
BioGPS NCI60210523_atGM16004.6184.660Details
BioGPS NCI60210523_atGM23134.5124.660Details
BioGPS NCI60210523_atGM23454.4684.660Details
BioGPS NCI60210523_atGM24934.7834.660Details
BioGPS NCI60210523_atGM974.9744.660Details
BioGPS NCI60210523_atHCC29984.1344.660Details
BioGPS NCI60210523_atHCT1164.4554.660Details
BioGPS NCI60210523_atHCT154.2494.660Details
BioGPS NCI60210523_atHEK 293 T-rex4.5194.660Details
BioGPS NCI60210523_atHEK 293T4.4524.660Details
BioGPS NCI60210523_atHEK2934.4424.660Details
BioGPS NCI60210523_atHELA4.2584.660Details
BioGPS NCI60210523_atHEPG24.4464.660Details
BioGPS NCI60210523_atHL607.9024.660Details
BioGPS NCI60210523_atHOP624.4744.660Details
BioGPS NCI60210523_atHOP924.3014.660Details
BioGPS NCI60210523_atHS578T4.4394.660Details
BioGPS NCI60210523_atHSG4.3494.660Details
BioGPS NCI60210523_atHT10804.4224.660Details
BioGPS NCI60210523_atHT294.7674.660Details
BioGPS NCI60210523_atIGROV14.5114.660Details
BioGPS NCI60210523_atIOSE804.4104.660Details
BioGPS NCI60210523_atJURKAT4.4534.660Details
BioGPS NCI60210523_atK5624.8714.660Details
BioGPS NCI60210523_atKM124.6654.660Details
BioGPS NCI60210523_atLN184.1634.660Details
BioGPS NCI60210523_atLNCAP4.4704.660Details
BioGPS NCI60210523_atLOX IMVI4.4494.660Details
BioGPS NCI60210523_atM144.4054.660Details
BioGPS NCI60210523_atMALME 3M4.8544.660Details
BioGPS NCI60210523_atMCF74.3274.660Details
BioGPS NCI60210523_atMD MB2314.4834.660Details
BioGPS NCI60210523_atMDA MB4354.7724.660Details
BioGPS NCI60210523_atMOLT44.6204.660Details
BioGPS NCI60210523_atNCI 4604.5264.660Details
BioGPS NCI60210523_atNCI H2264.5474.660Details
BioGPS NCI60210523_atNCI H234.4414.660Details
BioGPS NCI60210523_atNCI H322M4.4594.660Details
BioGPS NCI60210523_atNCVADR RES4.2304.660Details
BioGPS NCI60210523_atOVCAR34.6144.660Details
BioGPS NCI60210523_atOVCAR44.4634.660Details
BioGPS NCI60210523_atOVCAR54.3814.660Details
BioGPS NCI60210523_atOVCAR84.2304.660Details
BioGPS NCI60210523_atPANC14.4994.660Details
BioGPS NCI60210523_atRL74.5204.660Details
BioGPS NCI60210523_atRPMI 82264.4924.660Details
BioGPS NCI60210523_atRS118464.6534.660Details
BioGPS NCI60210523_atRXF3934.4494.660Details
BioGPS NCI60210523_atSAOS24.5214.660Details
BioGPS NCI60210523_atSF2684.4644.660Details
BioGPS NCI60210523_atSF2954.4114.660Details
BioGPS NCI60210523_atSF5394.2704.660Details
BioGPS NCI60210523_atSHSYSY+RA4.3814.660Details
BioGPS NCI60210523_atSHSYSY-RA4.4104.660Details
BioGPS NCI60210523_atSKMEL24.4434.660Details
BioGPS NCI60210523_atSKMEL284.4794.660Details
BioGPS NCI60210523_atSKMEL54.3304.660Details
BioGPS NCI60210523_atSKOV34.6434.660Details
BioGPS NCI60210523_atSN12C4.4214.660Details
BioGPS NCI60210523_atSNB194.2854.660Details
BioGPS NCI60210523_atSNB754.4414.660Details
BioGPS NCI60210523_atSR4.5444.660Details
BioGPS NCI60210523_atSW6204.4994.660Details
BioGPS NCI60210523_atT244.5344.660Details
BioGPS NCI60210523_atT3M44.6634.660Details
BioGPS NCI60210523_atTK104.6014.660Details
BioGPS NCI60210523_atU1184.3474.660Details
BioGPS NCI60210523_atU1384.2374.660Details
BioGPS NCI60210523_atU20S4.5664.660Details
BioGPS NCI60210523_atU2515.0474.660Details
BioGPS NCI60210523_atU874.3244.660Details
BioGPS NCI60210523_atUACC2574.3864.660Details
BioGPS NCI60210523_atUACC624.5614.660Details
BioGPS NCI60210523_atUO314.3084.660Details
BioGPS NCI60210523_atZR75_14.5884.660Details
BioGPS NCI60210523_atastrocytes4.5424.660Details
BioGPS NCI60210523_athuh-74.5994.660Details