Gene ID: 282991 | Bloc1s2 Antibody Resource
Bloc1s2 Antibody Resource
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Summary: | This gene encodes a protein with multiple functions. The encoded protein has been found in association with the centrosome, shown to co-localize with gamma-tubulin, and also found to be one of the proteins in the BLOC-1 complex which functions in the formation of lysosome-related organelles. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012] |
Function: | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. May play a role in cell proliferation. |
Subcellular location: | Cytoplasm › cytoskeleton › microtubule organizing center › centrosome. Note: Localizes to the centrosomes in a microtubule-dependent manner. |
PTM: | Acetylation; |
Disease: | |
Biotechnological use: |
Antibodies
| Type | Catalog | Name | Clonality | Species Reactivity | Application | Size | Price | More Info |
|---|---|---|---|---|---|---|---|---|
| Polyclonal Antibody | OAAB02952 | BLOC1S2 antibody - center region (OAAB02952) | Human; Mouse | WB, FC, IHC, ELISA | 400ul | $289 | Details | |
| Polyclonal Antibody | ARP55703_P050 | Bloc1s2 antibody - N-terminal region (ARP55703_P050) | Bovine, Dog, Horse, Human | WB | 50ug | $289 | Details | |
| Polyclonal Antibody | ARP55704_P050 | BLOC1S2 Antibody (ARP55704_P050) | Polyclonal | Bovine, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish | Not tested | 50 ug | $125 | Details |
Product Images
 Sample Type: Mouse Heart |
 Sample Type: HepG2 |
 Sample Type: HepG2 |
 Sample Type: human cervix carcinoma |
 Sample Type: mouse NIH-3T3 |
Bloc1s2 Protocols
- • Product Protocol: BLOC1S2 antibody tested with human cervix carcinoma in immunohistochemistry (IHC) (OAAB02952) Review
- • Product Protocol: BLOC1S2 antibody tested with human HepG2 by western blot (OAAB02952) Review
- • Product Protocol: BLOC1S2 antibody tested with mouse NIH-3T3 by western blot (OAAB02952) Review
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Publications
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Related Gene Trend Categories
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Species
| Catalog | Predicted Species & Target | Target Reference | Predicted Homology |
|---|---|---|---|
| ARP55703 | African clawed frog Bloc1s2 antibody; Xenopus laevis Bloc1s2 antibody | A1L2W6 | 100.0% |
| ARP55704 | African clawed frog Bloc1s2 antibody; Xenopus laevis Bloc1s2 antibody | A1L2W6 | 86.0% |
| ARP55703 | Bovine Bloc1s2 antibody; Bos taurus Bloc1s2 antibody | F1N5K4 | 100.0% |
| ARP55704 | Bovine Bloc1s2 antibody; Bos taurus Bloc1s2 antibody | F1N5K4 | 100.0% |
| ARP55703 | Bovine Bloc1s2 antibody; Bos taurus Bloc1s2 antibody | Q2TBU4 | 100.0% |
| ARP55704 | Bovine Bloc1s2 antibody; Bos taurus Bloc1s2 antibody | Q2TBU4 | 100.0% |
| ARP55703 | Cat Bloc1s2 antibody; Felis catus Bloc1s2 antibody | M3XDK6 | 100.0% |
| ARP55704 | Cat Bloc1s2 antibody; Felis catus Bloc1s2 antibody | M3XDK6 | 100.0% |
| ARP55703 | Chicken Bloc1s2 antibody; Gallus gallus Bloc1s2 antibody | E1BXG7 | 100.0% |
| ARP55704 | Chicken Bloc1s2 antibody; Gallus gallus Bloc1s2 antibody | E1BXG7 | 93.0% |
| ARP55704 | Chimpanzee Bloc1s2 antibody; Pan troglodytes Bloc1s2 antibody | H2RIH3 | 100.0% |
| ARP55703 | Chimpanzee Bloc1s2 antibody; Pan troglodytes Bloc1s2 antibody | K7BGJ2 | 100.0% |
| ARP55704 | Chimpanzee Bloc1s2 antibody; Pan troglodytes Bloc1s2 antibody | K7BGJ2 | 100.0% |
| ARP55703 | Chinese softshell turtle Bloc1s2 antibody; Pelodiscus sinensis Bloc1s2 antibody | K7G5B8 | 100.0% |
| ARP55704 | Chinese softshell turtle Bloc1s2 antibody; Pelodiscus sinensis Bloc1s2 antibody | K7G5B8 | 100.0% |
| ARP55703 | Collared flycatcher Bloc1s2 antibody; Ficedula albicollis Bloc1s2 antibody | U3JY50 | 100.0% |
| ARP55704 | Collared flycatcher Bloc1s2 antibody; Ficedula albicollis Bloc1s2 antibody | U3JY50 | 93.0% |
| ARP55703 | Crab-eating macaque Bloc1s2 antibody; Macaca fascicularis Bloc1s2 antibody | Q4R7C8 | 100.0% |
| ARP55704 | Crab-eating macaque Bloc1s2 antibody; Macaca fascicularis Bloc1s2 antibody | Q4R7C8 | 100.0% |
| ARP55703 | Dog Bloc1s2 antibody; Canis familiaris Bloc1s2 antibody | J9NRW6 | 100.0% |
| ARP55704 | Dog Bloc1s2 antibody; Canis familiaris Bloc1s2 antibody | J9NRW6 | 100.0% |
| ARP55703 | Domestic duck Bloc1s2 antibody; Anas platyrhynchos Bloc1s2 antibody | U3I529 | 100.0% |
| ARP55704 | Domestic duck Bloc1s2 antibody; Anas platyrhynchos Bloc1s2 antibody | U3I529 | 93.0% |
| ARP55704 | Duckbill platypus Bloc1s2 antibody; Ornithorhynchus anatinus Bloc1s2 antibody | F6W9Z7 | 93.0% |
| ARP55703 | Duckbill platypus Bloc1s2 antibody; Ornithorhynchus anatinus Bloc1s2 antibody | F6W9Z7 | 86.0% |
| ARP55703 | European domestic ferret Bloc1s2 antibody; Mustela putorius furo Bloc1s2 antibody | M3YZW0 | 100.0% |
| ARP55704 | European domestic ferret Bloc1s2 antibody; Mustela putorius furo Bloc1s2 antibody | M3YZW0 | 100.0% |
| ARP55703 | Giant panda Bloc1s2 antibody; Ailuropoda melanoleuca Bloc1s2 antibody | G1LJR2 | 100.0% |
| ARP55704 | Giant panda Bloc1s2 antibody; Ailuropoda melanoleuca Bloc1s2 antibody | G1LJR2 | 100.0% |
| ARP55703 | Horse Bloc1s2 antibody; Equus caballus Bloc1s2 antibody | F7BCZ6 | 100.0% |
| ARP55704 | Horse Bloc1s2 antibody; Equus caballus Bloc1s2 antibody | F7BCZ6 | 100.0% |
| ARP55703 | Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody | Q6QNY1-2 | 100.0% |
| ARP55704 | Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody | Q6QNY1-2 | 100.0% |
| ARP55703 | Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody | Q6QNY1 | 100.0% |
| ARP55704 | Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody | Q6QNY1 | 100.0% |
| ARP55703 | Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody | J3QRU7 | 100.0% |
| ARP55704 | Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody | J3QRU7 | 100.0% |
| ARP55703 | Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody | F1T0F0 | 100.0% |
| ARP55704 | Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody | F1T0F0 | 100.0% |
| ARP55703 | Mouse Bloc1s2 antibody; Mus musculus Bloc1s2 antibody | Q9CWG9 | 100.0% |
| ARP55704 | Mouse Bloc1s2 antibody; Mus musculus Bloc1s2 antibody | Q9CWG9 | 93.0% |
| ARP55703 | Pig Bloc1s2 antibody; Sus scrofa Bloc1s2 antibody | F1S8V1 | 100.0% |
| ARP55704 | Pig Bloc1s2 antibody; Sus scrofa Bloc1s2 antibody | F1S8V1 | 100.0% |
| ARP55703 | Rabbit Bloc1s2 antibody; Oryctolagus cuniculus Bloc1s2 antibody | G1T4T0 | 100.0% |
| ARP55704 | Rabbit Bloc1s2 antibody; Oryctolagus cuniculus Bloc1s2 antibody | G1T4T0 | 100.0% |
| ARP55704 | Rat Bloc1s2 antibody; Rattus norvegicus Bloc1s2 antibody | A0SXU1 | 100.0% |
| ARP55703 | Rat Bloc1s2 antibody; Rattus norvegicus Bloc1s2 antibody | Q32WR5 | 100.0% |
| ARP55704 | Rat Bloc1s2 antibody; Rattus norvegicus Bloc1s2 antibody | Q32WR5 | 100.0% |
| ARP55703 | Rhesus macaque Bloc1s2 antibody; Macaca mulatta Bloc1s2 antibody | H9EM67 | 100.0% |
| ARP55704 | Rhesus macaque Bloc1s2 antibody; Macaca mulatta Bloc1s2 antibody | H9EM67 | 100.0% |
| ARP55703 | Rhesus macaque Bloc1s2 antibody; Macaca mulatta Bloc1s2 antibody | F7GNY5 | 100.0% |
| ARP55704 | Rhesus macaque Bloc1s2 antibody; Macaca mulatta Bloc1s2 antibody | F7GNY5 | 100.0% |
| ARP55704 | Small-eared galago Bloc1s2 antibody; Otolemur garnettii Bloc1s2 antibody | H0WIH9 | 100.0% |
| ARP55703 | Small-eared galago Bloc1s2 antibody; Otolemur garnettii Bloc1s2 antibody | H0WIH9 | 100.0% |
| ARP55704 | Spotted green pufferfish Bloc1s2 antibody; Tetraodon nigroviridis Bloc1s2 antibody | Q4RL11 | 79.0% |
| ARP55703 | Sumatran orangutan Bloc1s2 antibody; Pongo abelii Bloc1s2 antibody | H2NBA7 | 100.0% |
| ARP55704 | Sumatran orangutan Bloc1s2 antibody; Pongo abelii Bloc1s2 antibody | H2NBA7 | 100.0% |
| ARP55703 | Western clawed frog Bloc1s2 antibody; Xenopus tropicalis Bloc1s2 antibody | Q66KB9 | 93.0% |
| ARP55704 | Western clawed frog Bloc1s2 antibody; Xenopus tropicalis Bloc1s2 antibody | Q66KB9 | 86.0% |
| ARP55703 | White-tufted-ear marmoset Bloc1s2 antibody; Callithrix jacchus Bloc1s2 antibody | U3DD90 | 100.0% |
| ARP55704 | White-tufted-ear marmoset Bloc1s2 antibody; Callithrix jacchus Bloc1s2 antibody | U3DD90 | 100.0% |
| ARP55703 | White-tufted-ear marmoset Bloc1s2 antibody; Callithrix jacchus Bloc1s2 antibody | F6XVK6 | 100.0% |
| ARP55704 | White-tufted-ear marmoset Bloc1s2 antibody; Callithrix jacchus Bloc1s2 antibody | F6XVK6 | 100.0% |
| ARP55703 | White-tufted-ear marmoset Bloc1s2 antibody; Callithrix jacchus Bloc1s2 antibody | F7IRI6 | 100.0% |
| ARP55704 | White-tufted-ear marmoset Bloc1s2 antibody; Callithrix jacchus Bloc1s2 antibody | F7IRI6 | 100.0% |
| ARP55703 | Zebra finch Bloc1s2 antibody; Taeniopygia guttata Bloc1s2 antibody | H0ZBN4 | 100.0% |
| ARP55704 | Zebra finch Bloc1s2 antibody; Taeniopygia guttata Bloc1s2 antibody | H0ZBN4 | 93.0% |
| ARP55704 | Zebrafish Bloc1s2 antibody; Danio rerio Bloc1s2 antibody | Q498W8 | 86.0% |
| ARP55703 | Zebrafish Bloc1s2 antibody; Danio rerio Bloc1s2 antibody | Q498W8 | 79.0% |
Tissue & Cell Line Gene Expression Data