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Gene ID: 282991 | Bloc1s2 Antibody Resource


Bloc1s2 Antibody Resource
Gene Full Name: 
biogenesis of lysosomal organelles complex-1, subunit 2
Uniprot: 
Q6QNY1
Protein Name: 
biogenesis of lysosome-related organelles complex 1 subunit 2
Nucleotide: 
NM_173809
Alias: 
CEAP;BLOS2;CEAP11;RP11-316M21.4;
Ensembl: 
Location: 
10q24.31
HPRD: 
12526
NCBI Gene: 
282991
MIM: 
609768

Summary: 
This gene encodes a protein with multiple functions. The encoded protein has been found in association with the centrosome, shown to co-localize with gamma-tubulin, and also found to be one of the proteins in the BLOC-1 complex which functions in the formation of lysosome-related organelles. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Function: 
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. May play a role in cell proliferation.
Subcellular location: 
Cytoplasm › cytoskeleton › microtubule organizing center › centrosome. Note: Localizes to the centrosomes in a microtubule-dependent manner.
PTM: 
Acetylation;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB02952 BLOC1S2 antibody - center region (OAAB02952) Human; Mouse WB, FC, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP55703_P050 Bloc1s2 antibody - N-terminal region (ARP55703_P050) Bovine, Dog, Horse, Human WB 50ug $289 Details
Polyclonal Antibody ARP55704_P050 BLOC1S2 Antibody (ARP55704_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details

Show all Bloc1s2 antibodies


Product Images
Bloc1s2 antibody - N-terminal region (ARP55703_P050) in Mouse Heart cells using Western Blot

Sample Type: Mouse Heart

BLOC1S2 antibody - center region (OAAB02952) in HepG2 cells using Western Blot

Sample Type: HepG2

BLOC1S2 antibody - center region (OAAB02952) in HepG2 cells using Flow Cytometry

Sample Type: HepG2

BLOC1S2 antibody - center region (OAAB02952) in human cervix carcinoma cells using Immunohistochemistry

Sample Type: human cervix carcinoma

BLOC1S2 antibody - center region (OAAB02952) in mouse NIH-3T3 cells using Western Blot

Sample Type: mouse NIH-3T3


Bloc1s2 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP55703 African clawed frog Bloc1s2 antibody; Xenopus laevis Bloc1s2 antibody A1L2W6 100.0%
ARP55704 African clawed frog Bloc1s2 antibody; Xenopus laevis Bloc1s2 antibody A1L2W6 86.0%
ARP55703 Bovine Bloc1s2 antibody; Bos taurus Bloc1s2 antibody F1N5K4 100.0%
ARP55704 Bovine Bloc1s2 antibody; Bos taurus Bloc1s2 antibody F1N5K4 100.0%
ARP55703 Bovine Bloc1s2 antibody; Bos taurus Bloc1s2 antibody Q2TBU4 100.0%
ARP55704 Bovine Bloc1s2 antibody; Bos taurus Bloc1s2 antibody Q2TBU4 100.0%
ARP55703 Cat Bloc1s2 antibody; Felis catus Bloc1s2 antibody M3XDK6 100.0%
ARP55704 Cat Bloc1s2 antibody; Felis catus Bloc1s2 antibody M3XDK6 100.0%
ARP55703 Chicken Bloc1s2 antibody; Gallus gallus Bloc1s2 antibody E1BXG7 100.0%
ARP55704 Chicken Bloc1s2 antibody; Gallus gallus Bloc1s2 antibody E1BXG7 93.0%
ARP55704 Chimpanzee Bloc1s2 antibody; Pan troglodytes Bloc1s2 antibody H2RIH3 100.0%
ARP55703 Chimpanzee Bloc1s2 antibody; Pan troglodytes Bloc1s2 antibody K7BGJ2 100.0%
ARP55704 Chimpanzee Bloc1s2 antibody; Pan troglodytes Bloc1s2 antibody K7BGJ2 100.0%
ARP55703 Chinese softshell turtle Bloc1s2 antibody; Pelodiscus sinensis Bloc1s2 antibody K7G5B8 100.0%
ARP55704 Chinese softshell turtle Bloc1s2 antibody; Pelodiscus sinensis Bloc1s2 antibody K7G5B8 100.0%
ARP55703 Collared flycatcher Bloc1s2 antibody; Ficedula albicollis Bloc1s2 antibody U3JY50 100.0%
ARP55704 Collared flycatcher Bloc1s2 antibody; Ficedula albicollis Bloc1s2 antibody U3JY50 93.0%
ARP55703 Crab-eating macaque Bloc1s2 antibody; Macaca fascicularis Bloc1s2 antibody Q4R7C8 100.0%
ARP55704 Crab-eating macaque Bloc1s2 antibody; Macaca fascicularis Bloc1s2 antibody Q4R7C8 100.0%
ARP55703 Dog Bloc1s2 antibody; Canis familiaris Bloc1s2 antibody J9NRW6 100.0%
ARP55704 Dog Bloc1s2 antibody; Canis familiaris Bloc1s2 antibody J9NRW6 100.0%
ARP55703 Domestic duck Bloc1s2 antibody; Anas platyrhynchos Bloc1s2 antibody U3I529 100.0%
ARP55704 Domestic duck Bloc1s2 antibody; Anas platyrhynchos Bloc1s2 antibody U3I529 93.0%
ARP55704 Duckbill platypus Bloc1s2 antibody; Ornithorhynchus anatinus Bloc1s2 antibody F6W9Z7 93.0%
ARP55703 Duckbill platypus Bloc1s2 antibody; Ornithorhynchus anatinus Bloc1s2 antibody F6W9Z7 86.0%
ARP55703 European domestic ferret Bloc1s2 antibody; Mustela putorius furo Bloc1s2 antibody M3YZW0 100.0%
ARP55704 European domestic ferret Bloc1s2 antibody; Mustela putorius furo Bloc1s2 antibody M3YZW0 100.0%
ARP55703 Giant panda Bloc1s2 antibody; Ailuropoda melanoleuca Bloc1s2 antibody G1LJR2 100.0%
ARP55704 Giant panda Bloc1s2 antibody; Ailuropoda melanoleuca Bloc1s2 antibody G1LJR2 100.0%
ARP55703 Horse Bloc1s2 antibody; Equus caballus Bloc1s2 antibody F7BCZ6 100.0%
ARP55704 Horse Bloc1s2 antibody; Equus caballus Bloc1s2 antibody F7BCZ6 100.0%
ARP55703 Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody Q6QNY1-2 100.0%
ARP55704 Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody Q6QNY1-2 100.0%
ARP55703 Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody Q6QNY1 100.0%
ARP55704 Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody Q6QNY1 100.0%
ARP55703 Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody J3QRU7 100.0%
ARP55704 Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody J3QRU7 100.0%
ARP55703 Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody F1T0F0 100.0%
ARP55704 Human Bloc1s2 antibody; Homo sapiens Bloc1s2 antibody F1T0F0 100.0%
ARP55703 Mouse Bloc1s2 antibody; Mus musculus Bloc1s2 antibody Q9CWG9 100.0%
ARP55704 Mouse Bloc1s2 antibody; Mus musculus Bloc1s2 antibody Q9CWG9 93.0%
ARP55703 Pig Bloc1s2 antibody; Sus scrofa Bloc1s2 antibody F1S8V1 100.0%
ARP55704 Pig Bloc1s2 antibody; Sus scrofa Bloc1s2 antibody F1S8V1 100.0%
ARP55703 Rabbit Bloc1s2 antibody; Oryctolagus cuniculus Bloc1s2 antibody G1T4T0 100.0%
ARP55704 Rabbit Bloc1s2 antibody; Oryctolagus cuniculus Bloc1s2 antibody G1T4T0 100.0%
ARP55704 Rat Bloc1s2 antibody; Rattus norvegicus Bloc1s2 antibody A0SXU1 100.0%
ARP55703 Rat Bloc1s2 antibody; Rattus norvegicus Bloc1s2 antibody Q32WR5 100.0%
ARP55704 Rat Bloc1s2 antibody; Rattus norvegicus Bloc1s2 antibody Q32WR5 100.0%
ARP55703 Rhesus macaque Bloc1s2 antibody; Macaca mulatta Bloc1s2 antibody H9EM67 100.0%
ARP55704 Rhesus macaque Bloc1s2 antibody; Macaca mulatta Bloc1s2 antibody H9EM67 100.0%
ARP55703 Rhesus macaque Bloc1s2 antibody; Macaca mulatta Bloc1s2 antibody F7GNY5 100.0%
ARP55704 Rhesus macaque Bloc1s2 antibody; Macaca mulatta Bloc1s2 antibody F7GNY5 100.0%
ARP55704 Small-eared galago Bloc1s2 antibody; Otolemur garnettii Bloc1s2 antibody H0WIH9 100.0%
ARP55703 Small-eared galago Bloc1s2 antibody; Otolemur garnettii Bloc1s2 antibody H0WIH9 100.0%
ARP55704 Spotted green pufferfish Bloc1s2 antibody; Tetraodon nigroviridis Bloc1s2 antibody Q4RL11 79.0%
ARP55703 Sumatran orangutan Bloc1s2 antibody; Pongo abelii Bloc1s2 antibody H2NBA7 100.0%
ARP55704 Sumatran orangutan Bloc1s2 antibody; Pongo abelii Bloc1s2 antibody H2NBA7 100.0%
ARP55703 Western clawed frog Bloc1s2 antibody; Xenopus tropicalis Bloc1s2 antibody Q66KB9 93.0%
ARP55704 Western clawed frog Bloc1s2 antibody; Xenopus tropicalis Bloc1s2 antibody Q66KB9 86.0%
ARP55703 White-tufted-ear marmoset Bloc1s2 antibody; Callithrix jacchus Bloc1s2 antibody U3DD90 100.0%
ARP55704 White-tufted-ear marmoset Bloc1s2 antibody; Callithrix jacchus Bloc1s2 antibody U3DD90 100.0%
ARP55703 White-tufted-ear marmoset Bloc1s2 antibody; Callithrix jacchus Bloc1s2 antibody F6XVK6 100.0%
ARP55704 White-tufted-ear marmoset Bloc1s2 antibody; Callithrix jacchus Bloc1s2 antibody F6XVK6 100.0%
ARP55703 White-tufted-ear marmoset Bloc1s2 antibody; Callithrix jacchus Bloc1s2 antibody F7IRI6 100.0%
ARP55704 White-tufted-ear marmoset Bloc1s2 antibody; Callithrix jacchus Bloc1s2 antibody F7IRI6 100.0%
ARP55703 Zebra finch Bloc1s2 antibody; Taeniopygia guttata Bloc1s2 antibody H0ZBN4 100.0%
ARP55704 Zebra finch Bloc1s2 antibody; Taeniopygia guttata Bloc1s2 antibody H0ZBN4 93.0%
ARP55704 Zebrafish Bloc1s2 antibody; Danio rerio Bloc1s2 antibody Q498W8 86.0%
ARP55703 Zebrafish Bloc1s2 antibody; Danio rerio Bloc1s2 antibody Q498W8 79.0%

Tissue & Cell Line Gene Expression Data