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Gene ID: 641 | BLM Antibody Resource


BLM Antibody Resource
Gene Full Name: 
Bloom syndrome, RecQ helicase-like
Uniprot: 
P54132
Protein Name: 
Bloom syndrome protein
Nucleotide: 
NM_000057
Alias: 
BS;RECQ2;RECQL2;RECQL3;
Ensembl: 
ENSG00000197299
Location: 
15q26.1
HPRD: 
05211
NCBI Gene: 
641
MIM: 
604610

Summary: 
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq, Jul 2008]
Function: 
Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE).
Subcellular location: 
Nucleus. Note: Together with SPIDR, is redistributed in discrete nuclear DNA damage-induced foci following hydroxyurea (HU) or camptothecin (CPT) treatment. Accumulated at sites of DNA damage in a RMI complex- and SPIDR-dependent manner.
PTM: 
Acetylation;
Disease: 
Bloom syndrome (BLM) [MIM:210900]: An autosomal recessive disorder. It is characterized by proportionate pre- and postnatal growth deficiency, sun-sensitive telangiectatic hypo- and hyperpigmented skin, predisposition to malignancy, and chromosomal instability. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OASA07463 BLM Antibody (OASA07463) Human IP, WB 50ug $410 Details
Polyclonal Antibody OAAB02275 BLM antibody - C-terminal region (OAAB02275) Human WB, FC, ELISA 400ul $289 Details
Polyclonal Antibody OAAB03873 BLM antibody - C-terminal region (OAAB03873) Human WB, IHC, FC, ELISA 400ul $289 Details
Blocking Peptide OESA09422 BLM BLOCKING PEPTIDE (50ug) Human 50ug $245 Details
Polyclonal Antibody ARP36338_P050 BLM Antibody (ARP36338_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAEC01988 Bloom Syndrome Protein (Phospho-Thr99)Antibody (OAEC01988) Human WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:40000 100ug $229 Details
Polyclonal Antibody OAAF00937 BLM Antibody (OAAF00937) Polyclonal Human IHC, IF, ELISA 100 ug $229 Details
Polyclonal Antibody OAAF00142 BLM (Phospho-Thr99) Antibody (OAAF00142) Polyclonal Human WB, IHC, ELISA 100 ug $229 Details

Show all BLM antibodies


Product Images
BLM antibody - C-terminal region (OAAB02275) in Hela cells using Flow Cytometry

Sample Type: Hela

BLM antibody - C-terminal region (OAAB02275) in HL-60 cells using Western Blot

Sample Type: HL-60

BLM (Phospho-Thr99) Antibody (OAAF00142) in HepG2 cells using Western Blot

Sample Type: HepG2

BLM (Phospho-Thr99) Antibody (OAAF00142) in Human heart cells using Immunohistochemistry

Sample Type: Human heart

BLM Antibody (OAAF00937) in A549 cells using Immunofluorescence

Sample Type: A549

BLM Antibody (OAAF00937) in Human lymph node cells using Immunohistochemistry

Sample Type: Human lymph node


BLM Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP36338 African elephant BLM antibody; Loxodonta africana BLM antibody G3T3J0 93.0%
ARP36338 Bovine BLM antibody; Bos taurus BLM antibody E1BQ04 92.0%
ARP72524 Bovine BLM antibody; Bos taurus BLM antibody E1BQ04 85.0%
ARP36338 Cat BLM antibody; Felis catus BLM antibody M3W592 86.0%
ARP36338 Chimpanzee BLM antibody; Pan troglodytes BLM antibody K7BX88 100.0%
ARP36338 Chimpanzee BLM antibody; Pan troglodytes BLM antibody K7D4C4 100.0%
ARP36338 Chimpanzee BLM antibody; Pan troglodytes BLM antibody H2QA33 100.0%
ARP72524 Chimpanzee BLM antibody; Pan troglodytes BLM antibody K7BX88 93.0%
ARP72524 Chimpanzee BLM antibody; Pan troglodytes BLM antibody K7D4C4 93.0%
ARP72524 Chimpanzee BLM antibody; Pan troglodytes BLM antibody H2QA33 93.0%
ARP36338 Dog BLM antibody; Canis familiaris BLM antibody J9PB86 86.0%
ARP36338 Dog BLM antibody; Canis familiaris BLM antibody E2RS76 86.0%
ARP36338 European domestic ferret BLM antibody; Mustela putorius furo BLM antibody M3YW37 92.0%
ARP72524 European domestic ferret BLM antibody; Mustela putorius furo BLM antibody M3YW37 85.0%
ARP36338 Green anole BLM antibody; Anolis carolinensis BLM antibody G1KPR4 85.0%
ARP36338 Horse BLM antibody; Equus caballus BLM antibody F6ZL78 86.0%
ARP72524 Horse BLM antibody; Equus caballus BLM antibody F6ZL78 79.0%
ARP36338 Human BLM antibody; Homo sapiens BLM antibody P54132 100.0%
ARP72524 Human BLM antibody; Homo sapiens BLM antibody P54132 100.0%
ARP36338 Human BLM antibody; Homo sapiens BLM antibody Q3B7X0 100.0%
ARP72524 Human BLM antibody; Homo sapiens BLM antibody Q3B7X0 100.0%
ARP36338 Human BLM antibody; Homo sapiens BLM antibody H0YLV8 100.0%
ARP72524 Human BLM antibody; Homo sapiens BLM antibody H0YLV8 100.0%
ARP36338 Human BLM antibody; Homo sapiens BLM antibody H0YNU5 100.0%
ARP72524 Human BLM antibody; Homo sapiens BLM antibody H0YNU5 100.0%
ARP36338 Mouse BLM antibody; Mus musculus BLM antibody E9PZ97 86.0%
ARP36338 Mouse BLM antibody; Mus musculus BLM antibody O88700 86.0%
ARP36338 Rabbit BLM antibody; Oryctolagus cuniculus BLM antibody G1T6H2 86.0%
ARP72524 Rhesus macaque BLM antibody; Macaca mulatta BLM antibody H9ZC96 100.0%
ARP36338 Rhesus macaque BLM antibody; Macaca mulatta BLM antibody F7CS38 100.0%
ARP72524 Rhesus macaque BLM antibody; Macaca mulatta BLM antibody F7CS38 100.0%
ARP36338 Rhesus macaque BLM antibody; Macaca mulatta BLM antibody H9ZC96 100.0%
ARP72524 Small-eared galago BLM antibody; Otolemur garnettii BLM antibody H0WSN6 86.0%
ARP36338 Small-eared galago BLM antibody; Otolemur garnettii BLM antibody H0WSN6 85.0%
ARP36338 Sumatran orangutan BLM antibody; Pongo abelii BLM antibody H2NP72 100.0%
ARP72524 Sumatran orangutan BLM antibody; Pongo abelii BLM antibody H2NP72 93.0%
ARP36338 White-tufted-ear marmoset BLM antibody; Callithrix jacchus BLM antibody F7ES97 100.0%
ARP36338 White-tufted-ear marmoset BLM antibody; Callithrix jacchus BLM antibody F7I4X7 100.0%
ARP72524 White-tufted-ear marmoset BLM antibody; Callithrix jacchus BLM antibody F7ES97 86.0%
ARP72524 White-tufted-ear marmoset BLM antibody; Callithrix jacchus BLM antibody F7I4X7 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas205733_at721_B_lymphoblasts110.10010.160Details
BioGPS Gene Atlas205733_atAdipocyte4.60010.160Details
BioGPS Gene Atlas205733_atAdrenalCortex4.70010.160Details
BioGPS Gene Atlas205733_atAdrenalgland3.90010.160Details
BioGPS Gene Atlas205733_atAmygdala4.85010.160Details
BioGPS Gene Atlas205733_atAppendix4.60010.160Details
BioGPS Gene Atlas205733_atAtrioventricularNode3.50010.160Details
BioGPS Gene Atlas205733_atBDCA4+_DentriticCells5.80010.160Details
BioGPS Gene Atlas205733_atBonemarrow4.50010.160Details
BioGPS Gene Atlas205733_atBronchialEpithelialCells4.60010.160Details
BioGPS Gene Atlas205733_atCD105+_Endothelial87.90010.160Details
BioGPS Gene Atlas205733_atCD14+_Monocytes5.00010.160Details
BioGPS Gene Atlas205733_atCD19+_BCells(neg._sel.)8.85010.160Details
BioGPS Gene Atlas205733_atCD33+_Myeloid5.75010.160Details
BioGPS Gene Atlas205733_atCD34+64.15010.160Details
BioGPS Gene Atlas205733_atCD4+_Tcells5.75010.160Details
BioGPS Gene Atlas205733_atCD56+_NKCells22.75010.160Details
BioGPS Gene Atlas205733_atCD71+_EarlyErythroid12.85010.160Details
BioGPS Gene Atlas205733_atCD8+_Tcells4.65010.160Details
BioGPS Gene Atlas205733_atCardiacMyocytes6.05010.160Details
BioGPS Gene Atlas205733_atCaudatenucleus4.15010.160Details
BioGPS Gene Atlas205733_atCerebellum3.80010.160Details
BioGPS Gene Atlas205733_atCerebellumPeduncles5.20010.160Details
BioGPS Gene Atlas205733_atCiliaryGanglion3.20010.160Details
BioGPS Gene Atlas205733_atCingulateCortex4.75010.160Details
BioGPS Gene Atlas205733_atColorectaladenocarcinoma4.85010.160Details
BioGPS Gene Atlas205733_atDorsalRootGanglion4.20010.160Details
BioGPS Gene Atlas205733_atFetalThyroid4.50010.160Details
BioGPS Gene Atlas205733_atFetalbrain4.60010.160Details
BioGPS Gene Atlas205733_atFetalliver4.00010.160Details
BioGPS Gene Atlas205733_atFetallung3.90010.160Details
BioGPS Gene Atlas205733_atGlobusPallidus3.60010.160Details
BioGPS Gene Atlas205733_atHeart5.75010.160Details
BioGPS Gene Atlas205733_atHypothalamus5.10010.160Details
BioGPS Gene Atlas205733_atKidney3.75010.160Details
BioGPS Gene Atlas205733_atLeukemia_chronicMyelogenousK-56229.25010.160Details
BioGPS Gene Atlas205733_atLeukemia_promyelocytic-HL-609.85010.160Details
BioGPS Gene Atlas205733_atLeukemialymphoblastic(MOLT-4)55.20010.160Details
BioGPS Gene Atlas205733_atLiver6.00010.160Details
BioGPS Gene Atlas205733_atLung5.10010.160Details
BioGPS Gene Atlas205733_atLymphnode4.30010.160Details
BioGPS Gene Atlas205733_atLymphoma_burkitts(Daudi)58.75010.160Details
BioGPS Gene Atlas205733_atLymphoma_burkitts(Raji)11.15010.160Details
BioGPS Gene Atlas205733_atMedullaOblongata4.30010.160Details
BioGPS Gene Atlas205733_atOccipitalLobe4.15010.160Details
BioGPS Gene Atlas205733_atOlfactoryBulb3.65010.160Details
BioGPS Gene Atlas205733_atOvary3.05010.160Details
BioGPS Gene Atlas205733_atPancreas3.70010.160Details
BioGPS Gene Atlas205733_atPancreaticIslet4.90010.160Details
BioGPS Gene Atlas205733_atParietalLobe4.80010.160Details
BioGPS Gene Atlas205733_atPituitary6.35010.160Details
BioGPS Gene Atlas205733_atPlacenta4.85010.160Details
BioGPS Gene Atlas205733_atPons4.40010.160Details
BioGPS Gene Atlas205733_atPrefrontalCortex5.55010.160Details
BioGPS Gene Atlas205733_atProstate5.50010.160Details
BioGPS Gene Atlas205733_atSalivarygland23.85010.160Details
BioGPS Gene Atlas205733_atSkeletalMuscle23.50010.160Details
BioGPS Gene Atlas205733_atSkin3.55010.160Details
BioGPS Gene Atlas205733_atSmoothMuscle13.15010.160Details
BioGPS Gene Atlas205733_atSpinalcord4.95010.160Details
BioGPS Gene Atlas205733_atSubthalamicNucleus6.40010.160Details
BioGPS Gene Atlas205733_atSuperiorCervicalGanglion5.10010.160Details
BioGPS Gene Atlas205733_atTemporalLobe4.20010.160Details
BioGPS Gene Atlas205733_atTestis4.45010.160Details
BioGPS Gene Atlas205733_atTestisGermCell4.15010.160Details
BioGPS Gene Atlas205733_atTestisIntersitial3.90010.160Details
BioGPS Gene Atlas205733_atTestisLeydigCell5.05010.160Details
BioGPS Gene Atlas205733_atTestisSeminiferousTubule7.05010.160Details
BioGPS Gene Atlas205733_atThalamus4.70010.160Details
BioGPS Gene Atlas205733_atThymus4.80010.160Details
BioGPS Gene Atlas205733_atThyroid5.85010.160Details
BioGPS Gene Atlas205733_atTongue5.25010.160Details
BioGPS Gene Atlas205733_atTonsil15.75010.160Details
BioGPS Gene Atlas205733_atTrachea3.90010.160Details
BioGPS Gene Atlas205733_atTrigeminalGanglion4.50010.160Details
BioGPS Gene Atlas205733_atUterus3.75010.160Details
BioGPS Gene Atlas205733_atUterusCorpus4.25010.160Details
BioGPS Gene Atlas205733_atWholeBlood5.20010.160Details
BioGPS Gene Atlas205733_atWholebrain4.00010.160Details
BioGPS Gene Atlas205733_atcolon4.65010.160Details
BioGPS Gene Atlas205733_atpineal_day5.84010.160Details
BioGPS Gene Atlas205733_atpineal_night5.42010.160Details
BioGPS Gene Atlas205733_atretina5.45010.160Details
BioGPS Gene Atlas205733_atsmall_intestine4.35010.160Details
BioGPS NCI60205733_at78629.28763.190Details
BioGPS NCI60205733_atA1729.14163.190Details
BioGPS NCI60205733_atA20421.35363.190Details
BioGPS NCI60205733_atA36167.62763.190Details
BioGPS NCI60205733_atA49811.86763.190Details
BioGPS NCI60205733_atA54963.38363.190Details
BioGPS NCI60205733_atACC3131.77763.190Details
BioGPS NCI60205733_atACHN9.88363.190Details
BioGPS NCI60205733_atALVA3111.72763.190Details
BioGPS NCI60205733_atCAKI14.71663.190Details
BioGPS NCI60205733_atCCRT CEM207.64363.190Details
BioGPS NCI60205733_atCOLO205187.45163.190Details
BioGPS NCI60205733_atDLD1187.86063.190Details
BioGPS NCI60205733_atDU14587.73763.190Details
BioGPS NCI60205733_atEKVX56.85963.190Details
BioGPS NCI60205733_atGM13371.92863.190Details
BioGPS NCI60205733_atGM160012.40763.190Details
BioGPS NCI60205733_atGM231363.89063.190Details
BioGPS NCI60205733_atGM234511.98463.190Details
BioGPS NCI60205733_atGM249318.26763.190Details
BioGPS NCI60205733_atGM9713.10163.190Details
BioGPS NCI60205733_atHCC299840.94263.190Details
BioGPS NCI60205733_atHCT116180.15463.190Details
BioGPS NCI60205733_atHCT15104.19463.190Details
BioGPS NCI60205733_atHEK 293 T-rex170.42963.190Details
BioGPS NCI60205733_atHEK 293T306.55063.190Details
BioGPS NCI60205733_atHEK293100.64763.190Details
BioGPS NCI60205733_atHELA92.87063.190Details
BioGPS NCI60205733_atHEPG284.27163.190Details
BioGPS NCI60205733_atHL6075.08863.190Details
BioGPS NCI60205733_atHOP6211.43363.190Details
BioGPS NCI60205733_atHOP9210.79463.190Details
BioGPS NCI60205733_atHS578T9.21863.190Details
BioGPS NCI60205733_atHSG146.13663.190Details
BioGPS NCI60205733_atHT10809.97763.190Details
BioGPS NCI60205733_atHT29189.40263.190Details
BioGPS NCI60205733_atIGROV111.77663.190Details
BioGPS NCI60205733_atIOSE8039.21263.190Details
BioGPS NCI60205733_atJURKAT212.53463.190Details
BioGPS NCI60205733_atK562172.70263.190Details
BioGPS NCI60205733_atKM1247.17663.190Details
BioGPS NCI60205733_atLN187.53363.190Details
BioGPS NCI60205733_atLNCAP16.22363.190Details
BioGPS NCI60205733_atLOX IMVI18.75163.190Details
BioGPS NCI60205733_atM14297.80263.190Details
BioGPS NCI60205733_atMALME 3M36.19963.190Details
BioGPS NCI60205733_atMCF740.85663.190Details
BioGPS NCI60205733_atMD MB23110.80763.190Details
BioGPS NCI60205733_atMDA MB4355.21763.190Details
BioGPS NCI60205733_atMOLT4170.59963.190Details
BioGPS NCI60205733_atNCI 46019.80663.190Details
BioGPS NCI60205733_atNCI H226110.07063.190Details
BioGPS NCI60205733_atNCI H2350.97463.190Details
BioGPS NCI60205733_atNCI H322M19.27663.190Details
BioGPS NCI60205733_atNCVADR RES12.35263.190Details
BioGPS NCI60205733_atOVCAR312.66563.190Details
BioGPS NCI60205733_atOVCAR428.90363.190Details
BioGPS NCI60205733_atOVCAR538.71563.190Details
BioGPS NCI60205733_atOVCAR831.63863.190Details
BioGPS NCI60205733_atPANC110.79763.190Details
BioGPS NCI60205733_atRL7195.55863.190Details
BioGPS NCI60205733_atRPMI 822664.02263.190Details
BioGPS NCI60205733_atRS1184699.07463.190Details
BioGPS NCI60205733_atRXF39317.03363.190Details
BioGPS NCI60205733_atSAOS231.12363.190Details
BioGPS NCI60205733_atSF26811.88263.190Details
BioGPS NCI60205733_atSF29510.60363.190Details
BioGPS NCI60205733_atSF53947.98663.190Details
BioGPS NCI60205733_atSHSYSY+RA83.01663.190Details
BioGPS NCI60205733_atSHSYSY-RA53.56663.190Details
BioGPS NCI60205733_atSKMEL224.73863.190Details
BioGPS NCI60205733_atSKMEL2810.00263.190Details
BioGPS NCI60205733_atSKMEL532.04963.190Details
BioGPS NCI60205733_atSKOV365.38363.190Details
BioGPS NCI60205733_atSN12C10.04563.190Details
BioGPS NCI60205733_atSNB1922.18363.190Details
BioGPS NCI60205733_atSNB755.11163.190Details
BioGPS NCI60205733_atSR91.06563.190Details
BioGPS NCI60205733_atSW620220.21763.190Details
BioGPS NCI60205733_atT24100.69963.190Details
BioGPS NCI60205733_atT3M412.34863.190Details
BioGPS NCI60205733_atTK1075.26763.190Details
BioGPS NCI60205733_atU1187.13063.190Details
BioGPS NCI60205733_atU13810.26163.190Details
BioGPS NCI60205733_atU20S29.54763.190Details
BioGPS NCI60205733_atU25132.88563.190Details
BioGPS NCI60205733_atU8715.78663.190Details
BioGPS NCI60205733_atUACC25731.99063.190Details
BioGPS NCI60205733_atUACC625.96663.190Details
BioGPS NCI60205733_atUO3121.63163.190Details
BioGPS NCI60205733_atZR75_111.50963.190Details
BioGPS NCI60205733_atastrocytes7.83563.190Details
BioGPS NCI60205733_athuh-725.87263.190Details