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Gene ID: 27319 | BHLHE22 Antibody Resource


BHLHE22 Antibody Resource
Gene Full Name: 
basic helix-loop-helix family, member e22
Uniprot: 
Q8NFJ8
Protein Name: 
class E basic helix-loop-helix protein 22
Nucleotide: 
NM_152414
Alias: 
Beta3;BHLHB5;CAGL85;TNRC20;
Ensembl: 
ENSG00000180828
Location: 
8q13
HPRD: 
16551
NCBI Gene: 
27319
MIM: 
613483

Summary: 
BHLHE22 belongs to the basic helix-loop-helix (bHLH) family of transcription factors that regulate cell fate determination, proliferation, and differentiation. These proteins function as dimers and bind to an E-box DNA sequence (CANNTG). BHLHE22 is expressed exclusively in the central nervous system and retina (Xu et al., 2002 [PubMed 12213201]).[supplied by OMIM, Jul 2010]
Function: 
Inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA .
Subcellular location: 
Nucleus Probable.
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP32430_T100 BHLHB5 antibody - N-terminal region (ARP32430_T100) Polyclonal Human; Mouse; Rat; Zebra Fish WB 100ug $229 Details
Polyclonal Antibody ARP32430_P050 BHLHB5 antibody - N-terminal region (ARP32430_P050) Polyclonal Bovine, Human, Mouse, Rat, Zebrafish WB 50ug $289 Details
Polyclonal Antibody OAAB02197 BHLHE22 antibody - center region (OAAB02197) Human WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP31882_P050 BHLHE22 Antibody (ARP31882_P050) Polyclonal Bovine, Guinea pig, Human, Pig, Rabbit, Rat Not tested 50 ug $50 Details

Show all BHLHE22 antibodies


Product Images
BHLHB5 antibody - N-terminal region (ARP32430_P050) in Human Jurkat cells using Western Blot

Sample Type: Human Jurkat

BHLHB5 antibody - N-terminal region (ARP32430_T100) in Human Jurkat cells using Western Blot

Sample Type: Human Jurkat

BHLHE22 antibody - center region (OAAB02197) in HL-60 cells using Western Blot

Sample Type: HL-60

BHLHE22 antibody - center region (OAAB02197) in human brain cells using Immunohistochemistry

Sample Type: human brain


BHLHE22 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP32430 Chicken BHLHE22 antibody; Gallus gallus BHLHE22 antibody Q71T09 100.0%
ARP32430 European seabass BHLHE22 antibody; Dicentrarchus labrax BHLHE22 antibody E6ZIR0 100.0%
ARP32430 Golden hamster BHLHE22 antibody; Mesocricetus auratus BHLHE22 antibody O09029 100.0%
ARP31882 Golden hamster BHLHE22 antibody; Mesocricetus auratus BHLHE22 antibody O09029 86.0%
ARP32430 Gray short-tailed opossum BHLHE22 antibody; Monodelphis domestica BHLHE22 antibody F6ZY60 100.0%
ARP31882 Human BHLHE22 antibody; Homo sapiens BHLHE22 antibody Q8NFJ8 100.0%
ARP32430 Human BHLHE22 antibody; Homo sapiens BHLHE22 antibody Q8NFJ8 100.0%
ARP32430 Mouse BHLHE22 antibody; Mus musculus BHLHE22 antibody Q8C6A8 100.0%
ARP32430 Pig BHLHE22 antibody; Sus scrofa BHLHE22 antibody F1RTA8 100.0%
ARP31882 Pig BHLHE22 antibody; Sus scrofa BHLHE22 antibody F1RTA8 86.0%
ARP32430 Rabbit BHLHE22 antibody; Oryctolagus cuniculus BHLHE22 antibody G1TRN6 100.0%
ARP31882 Rabbit BHLHE22 antibody; Oryctolagus cuniculus BHLHE22 antibody G1TRN6 93.0%
ARP32430 Rat BHLHE22 antibody; Rattus norvegicus BHLHE22 antibody D4A287 93.0%
ARP31882 Rat BHLHE22 antibody; Rattus norvegicus BHLHE22 antibody D4A287 79.0%
ARP32430 Rhesus macaque BHLHE22 antibody; Macaca mulatta BHLHE22 antibody F6TCE4 100.0%
ARP32430 Rhesus macaque BHLHE22 antibody; Macaca mulatta BHLHE22 antibody I2CUM2 100.0%
ARP31882 Rhesus macaque BHLHE22 antibody; Macaca mulatta BHLHE22 antibody F6TCE4 93.0%
ARP31882 Rhesus macaque BHLHE22 antibody; Macaca mulatta BHLHE22 antibody I2CUM2 93.0%
ARP32430 Small-eared galago BHLHE22 antibody; Otolemur garnettii BHLHE22 antibody H0XYI6 100.0%
ARP31882 Small-eared galago BHLHE22 antibody; Otolemur garnettii BHLHE22 antibody H0XYI6 93.0%
ARP32430 Sumatran orangutan BHLHE22 antibody; Pongo abelii BHLHE22 antibody H2PQF3 100.0%
ARP31882 Sumatran orangutan BHLHE22 antibody; Pongo abelii BHLHE22 antibody H2PQF3 93.0%
ARP32430 West Indian ocean coelacanth BHLHE22 antibody; Latimeria chalumnae BHLHE22 antibody H3AE80 100.0%
ARP32430 Western clawed frog BHLHE22 antibody; Xenopus tropicalis BHLHE22 antibody Q0V9X5 93.0%
ARP32430 White-tufted-ear marmoset BHLHE22 antibody; Callithrix jacchus BHLHE22 antibody F6UDG3 100.0%
ARP32430 White-tufted-ear marmoset BHLHE22 antibody; Callithrix jacchus BHLHE22 antibody F6UDW8 100.0%
ARP31882 White-tufted-ear marmoset BHLHE22 antibody; Callithrix jacchus BHLHE22 antibody F6UDW8 92.0%
ARP31882 White-tufted-ear marmoset BHLHE22 antibody; Callithrix jacchus BHLHE22 antibody F6UDG3 86.0%
ARP32430 Zebrafish BHLHE22 antibody; Danio rerio BHLHE22 antibody F1R9F5 100.0%
ARP32430 Zebrafish BHLHE22 antibody; Danio rerio BHLHE22 antibody Q7T301 100.0%

Tissue & Cell Line Gene Expression Data