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Gene ID: 79738 | BBS10 Antibody Resource


BBS10 Antibody Resource
Gene Full Name: 
Bardet-Biedl syndrome 10
Uniprot: 
Q8TAM1
Protein Name: 
Bardet-Biedl syndrome 10 protein
Nucleotide: 
NM_024685
Alias: 
C12orf58;
Ensembl: 
ENSG00000179941
Location: 
12q21.2
HPRD: 
08036
NCBI Gene: 
79738
MIM: 
610148

Summary: 
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10. [provided by RefSeq, Jan 2010]
Function: 
Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.
Subcellular location: 
Cell projection › cilium. Note: Located within the basal body of the primary cilium of differentiating preadipocytes.
PTM: 
Disease: 
Bardet-Biedl syndrome 10 (BBS10) [MIM:209900]: A syndrome characterized by usually severe pigmentary retinopathy, early-onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. Secondary features include diabetes mellitus, hypertension and congenital heart disease. Bardet-Biedl syndrome inheritance is autosomal recessive, but three mutated alleles (two at one locus, and a third at a second locus) may be required for clinical manifestation of some forms of the disease. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP59803_P050 BBS10 antibody - C-terminal region (ARP59803_P050) Polyclonal Human, Rabbit WB 50ug $289 Details
Polyclonal Antibody OAAB02296 BBS10 antibody - C-terminal region (OAAB02296) Human WB, FC, ELISA 400ul $289 Details
Polyclonal Antibody ARP59804_P050 BBS10 Antibody (ARP59804_P050) Polyclonal Horse, Human, Rabbit Not tested 50 ug $125 Details
Polyclonal Antibody OAGA00768 BBS10 antibody (OAGA00768) Polyclonal Human IHC (Formalin-fixed paraffin-embedded sections), WB 100 ul $340 Details

Show all BBS10 antibodies


Product Images
BBS10 antibody - C-terminal region (ARP59803_P050) in Human 293T cells using Western Blot

Sample Type: Human 293T

BBS10 antibody - C-terminal region (OAAB02296) in NCI-H460 cells using Western Blot

Sample Type: NCI-H460

BBS10 antibody - C-terminal region (OAAB02296) in NCI-H460 cells using Flow Cytometry

Sample Type: NCI-H460


BBS10 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP59803 Chimpanzee BBS10 antibody; Pan troglodytes BBS10 antibody H2Q6I5 100.0%
ARP59803 Chimpanzee BBS10 antibody; Pan troglodytes BBS10 antibody K7BN20 100.0%
ARP59803 Chimpanzee BBS10 antibody; Pan troglodytes BBS10 antibody K7D3W5 100.0%
ARP59804 Chimpanzee BBS10 antibody; Pan troglodytes BBS10 antibody H2Q6I5 93.0%
ARP59804 Chimpanzee BBS10 antibody; Pan troglodytes BBS10 antibody K7BN20 93.0%
ARP59804 Chimpanzee BBS10 antibody; Pan troglodytes BBS10 antibody K7D3W5 93.0%
ARP59803 Human BBS10 antibody; Homo sapiens BBS10 antibody Q8TAM1 100.0%
ARP59804 Human BBS10 antibody; Homo sapiens BBS10 antibody Q8TAM1 100.0%
ARP59803 Rabbit BBS10 antibody; Oryctolagus cuniculus BBS10 antibody G1SZG9 86.0%
ARP59803 Rhesus macaque BBS10 antibody; Macaca mulatta BBS10 antibody F7DPW6 100.0%
ARP59803 Rhesus macaque BBS10 antibody; Macaca mulatta BBS10 antibody H9FZV7 100.0%
ARP59804 Rhesus macaque BBS10 antibody; Macaca mulatta BBS10 antibody F7DPW6 92.0%
ARP59804 Rhesus macaque BBS10 antibody; Macaca mulatta BBS10 antibody H9FZV7 92.0%
ARP59803 Small-eared galago BBS10 antibody; Otolemur garnettii BBS10 antibody H0XKK6 79.0%
ARP59803 Sumatran orangutan BBS10 antibody; Pongo abelii BBS10 antibody H2NI41 100.0%
ARP59803 Sumatran orangutan BBS10 antibody; Pongo abelii BBS10 antibody Q5R8P3 100.0%
ARP59804 Sumatran orangutan BBS10 antibody; Pongo abelii BBS10 antibody H2NI41 92.0%
ARP59804 Sumatran orangutan BBS10 antibody; Pongo abelii BBS10 antibody Q5R8P3 92.0%
ARP59803 White-tufted-ear marmoset BBS10 antibody; Callithrix jacchus BBS10 antibody F6YBY1 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas219487_at721_B_lymphoblasts10.90011.210Details
BioGPS Gene Atlas219487_atAdipocyte9.60011.210Details
BioGPS Gene Atlas219487_atAdrenalCortex12.85011.210Details
BioGPS Gene Atlas219487_atAdrenalgland9.20011.210Details
BioGPS Gene Atlas219487_atAmygdala14.10011.210Details
BioGPS Gene Atlas219487_atAppendix14.05011.210Details
BioGPS Gene Atlas219487_atAtrioventricularNode12.50011.210Details
BioGPS Gene Atlas219487_atBDCA4+_DentriticCells10.00011.210Details
BioGPS Gene Atlas219487_atBonemarrow11.10011.210Details
BioGPS Gene Atlas219487_atBronchialEpithelialCells9.35011.210Details
BioGPS Gene Atlas219487_atCD105+_Endothelial9.90011.210Details
BioGPS Gene Atlas219487_atCD14+_Monocytes10.80011.210Details
BioGPS Gene Atlas219487_atCD19+_BCells(neg._sel.)10.40011.210Details
BioGPS Gene Atlas219487_atCD33+_Myeloid11.80011.210Details
BioGPS Gene Atlas219487_atCD34+19.05011.210Details
BioGPS Gene Atlas219487_atCD4+_Tcells9.45011.210Details
BioGPS Gene Atlas219487_atCD56+_NKCells14.25011.210Details
BioGPS Gene Atlas219487_atCD71+_EarlyErythroid9.50011.210Details
BioGPS Gene Atlas219487_atCD8+_Tcells9.10011.210Details
BioGPS Gene Atlas219487_atCardiacMyocytes17.95011.210Details
BioGPS Gene Atlas219487_atCaudatenucleus8.90011.210Details
BioGPS Gene Atlas219487_atCerebellum8.10011.210Details
BioGPS Gene Atlas219487_atCerebellumPeduncles12.45011.210Details
BioGPS Gene Atlas219487_atCiliaryGanglion9.80011.210Details
BioGPS Gene Atlas219487_atCingulateCortex10.50011.210Details
BioGPS Gene Atlas219487_atColorectaladenocarcinoma9.30011.210Details
BioGPS Gene Atlas219487_atDorsalRootGanglion9.10011.210Details
BioGPS Gene Atlas219487_atFetalThyroid10.40011.210Details
BioGPS Gene Atlas219487_atFetalbrain9.40011.210Details
BioGPS Gene Atlas219487_atFetalliver8.80011.210Details
BioGPS Gene Atlas219487_atFetallung7.65011.210Details
BioGPS Gene Atlas219487_atGlobusPallidus8.55011.210Details
BioGPS Gene Atlas219487_atHeart16.60011.210Details
BioGPS Gene Atlas219487_atHypothalamus10.70011.210Details
BioGPS Gene Atlas219487_atKidney9.60011.210Details
BioGPS Gene Atlas219487_atLeukemia_chronicMyelogenousK-5628.75011.210Details
BioGPS Gene Atlas219487_atLeukemia_promyelocytic-HL-608.65011.210Details
BioGPS Gene Atlas219487_atLeukemialymphoblastic(MOLT-4)6.95011.210Details
BioGPS Gene Atlas219487_atLiver15.50011.210Details
BioGPS Gene Atlas219487_atLung10.40011.210Details
BioGPS Gene Atlas219487_atLymphnode7.90011.210Details
BioGPS Gene Atlas219487_atLymphoma_burkitts(Daudi)13.10011.210Details
BioGPS Gene Atlas219487_atLymphoma_burkitts(Raji)15.55011.210Details
BioGPS Gene Atlas219487_atMedullaOblongata8.75011.210Details
BioGPS Gene Atlas219487_atOccipitalLobe8.90011.210Details
BioGPS Gene Atlas219487_atOlfactoryBulb7.65011.210Details
BioGPS Gene Atlas219487_atOvary7.45011.210Details
BioGPS Gene Atlas219487_atPancreas8.40011.210Details
BioGPS Gene Atlas219487_atPancreaticIslet11.05011.210Details
BioGPS Gene Atlas219487_atParietalLobe12.00011.210Details
BioGPS Gene Atlas219487_atPituitary11.50011.210Details
BioGPS Gene Atlas219487_atPlacenta8.75011.210Details
BioGPS Gene Atlas219487_atPons10.00011.210Details
BioGPS Gene Atlas219487_atPrefrontalCortex12.10011.210Details
BioGPS Gene Atlas219487_atProstate11.15011.210Details
BioGPS Gene Atlas219487_atSalivarygland8.25011.210Details
BioGPS Gene Atlas219487_atSkeletalMuscle15.35011.210Details
BioGPS Gene Atlas219487_atSkin9.45011.210Details
BioGPS Gene Atlas219487_atSmoothMuscle11.35011.210Details
BioGPS Gene Atlas219487_atSpinalcord10.55011.210Details
BioGPS Gene Atlas219487_atSubthalamicNucleus9.60011.210Details
BioGPS Gene Atlas219487_atSuperiorCervicalGanglion16.50011.210Details
BioGPS Gene Atlas219487_atTemporalLobe9.60011.210Details
BioGPS Gene Atlas219487_atTestis8.10011.210Details
BioGPS Gene Atlas219487_atTestisGermCell7.35011.210Details
BioGPS Gene Atlas219487_atTestisIntersitial8.30011.210Details
BioGPS Gene Atlas219487_atTestisLeydigCell10.95011.210Details
BioGPS Gene Atlas219487_atTestisSeminiferousTubule8.30011.210Details
BioGPS Gene Atlas219487_atThalamus10.55011.210Details
BioGPS Gene Atlas219487_atThymus7.35011.210Details
BioGPS Gene Atlas219487_atThyroid15.20011.210Details
BioGPS Gene Atlas219487_atTongue11.35011.210Details
BioGPS Gene Atlas219487_atTonsil9.80011.210Details
BioGPS Gene Atlas219487_atTrachea7.80011.210Details
BioGPS Gene Atlas219487_atTrigeminalGanglion14.95011.210Details
BioGPS Gene Atlas219487_atUterus8.05011.210Details
BioGPS Gene Atlas219487_atUterusCorpus10.50011.210Details
BioGPS Gene Atlas219487_atWholeBlood11.25011.210Details
BioGPS Gene Atlas219487_atWholebrain9.15011.210Details
BioGPS Gene Atlas219487_atcolon9.85011.210Details
BioGPS Gene Atlas219487_atpineal_day18.58011.210Details
BioGPS Gene Atlas219487_atpineal_night22.20011.210Details
BioGPS Gene Atlas219487_atretina12.77511.210Details
BioGPS Gene Atlas219487_atsmall_intestine9.35011.210Details
BioGPS NCI60219487_at78612.48523.640Details
BioGPS NCI60219487_atA172175.27423.640Details
BioGPS NCI60219487_atA20429.85723.640Details
BioGPS NCI60219487_atA36112.33123.640Details
BioGPS NCI60219487_atA49811.43123.640Details
BioGPS NCI60219487_atA54915.92923.640Details
BioGPS NCI60219487_atACC318.73423.640Details
BioGPS NCI60219487_atACHN12.24223.640Details
BioGPS NCI60219487_atALVA3114.14323.640Details
BioGPS NCI60219487_atCAKI115.13523.640Details
BioGPS NCI60219487_atCCRT CEM15.68223.640Details
BioGPS NCI60219487_atCOLO20512.30723.640Details
BioGPS NCI60219487_atDLD110.75423.640Details
BioGPS NCI60219487_atDU14512.28623.640Details
BioGPS NCI60219487_atEKVX13.14623.640Details
BioGPS NCI60219487_atGM13336.91223.640Details
BioGPS NCI60219487_atGM160047.38023.640Details
BioGPS NCI60219487_atGM231330.14323.640Details
BioGPS NCI60219487_atGM234547.90623.640Details
BioGPS NCI60219487_atGM249332.31323.640Details
BioGPS NCI60219487_atGM9715.66123.640Details
BioGPS NCI60219487_atHCC299812.02023.640Details
BioGPS NCI60219487_atHCT11614.61023.640Details
BioGPS NCI60219487_atHCT159.97523.640Details
BioGPS NCI60219487_atHEK 293 T-rex24.55223.640Details
BioGPS NCI60219487_atHEK 293T38.28923.640Details
BioGPS NCI60219487_atHEK29348.08623.640Details
BioGPS NCI60219487_atHELA10.98923.640Details
BioGPS NCI60219487_atHEPG212.93623.640Details
BioGPS NCI60219487_atHL6013.58023.640Details
BioGPS NCI60219487_atHOP6212.39023.640Details
BioGPS NCI60219487_atHOP9211.05023.640Details
BioGPS NCI60219487_atHS578T12.12023.640Details
BioGPS NCI60219487_atHSG10.27723.640Details
BioGPS NCI60219487_atHT1080170.96823.640Details
BioGPS NCI60219487_atHT2914.84723.640Details
BioGPS NCI60219487_atIGROV111.02023.640Details
BioGPS NCI60219487_atIOSE8012.05623.640Details
BioGPS NCI60219487_atJURKAT11.52723.640Details
BioGPS NCI60219487_atK56214.24423.640Details
BioGPS NCI60219487_atKM1213.06923.640Details
BioGPS NCI60219487_atLN18118.70823.640Details
BioGPS NCI60219487_atLNCAP53.20123.640Details
BioGPS NCI60219487_atLOX IMVI13.32523.640Details
BioGPS NCI60219487_atM1411.90923.640Details
BioGPS NCI60219487_atMALME 3M13.58023.640Details
BioGPS NCI60219487_atMCF711.10023.640Details
BioGPS NCI60219487_atMD MB23113.18923.640Details
BioGPS NCI60219487_atMDA MB43513.88123.640Details
BioGPS NCI60219487_atMOLT413.05423.640Details
BioGPS NCI60219487_atNCI 46013.48723.640Details
BioGPS NCI60219487_atNCI H22614.79923.640Details
BioGPS NCI60219487_atNCI H2312.84423.640Details
BioGPS NCI60219487_atNCI H322M10.61123.640Details
BioGPS NCI60219487_atNCVADR RES9.20323.640Details
BioGPS NCI60219487_atOVCAR313.51923.640Details
BioGPS NCI60219487_atOVCAR410.65123.640Details
BioGPS NCI60219487_atOVCAR511.42223.640Details
BioGPS NCI60219487_atOVCAR89.32423.640Details
BioGPS NCI60219487_atPANC113.09123.640Details
BioGPS NCI60219487_atRL713.25423.640Details
BioGPS NCI60219487_atRPMI 822614.10823.640Details
BioGPS NCI60219487_atRS1184613.49223.640Details
BioGPS NCI60219487_atRXF39312.59123.640Details
BioGPS NCI60219487_atSAOS211.56823.640Details
BioGPS NCI60219487_atSF26811.60423.640Details
BioGPS NCI60219487_atSF2959.67923.640Details
BioGPS NCI60219487_atSF5398.54923.640Details
BioGPS NCI60219487_atSHSYSY+RA12.33823.640Details
BioGPS NCI60219487_atSHSYSY-RA12.84223.640Details
BioGPS NCI60219487_atSKMEL212.11323.640Details
BioGPS NCI60219487_atSKMEL2811.50623.640Details
BioGPS NCI60219487_atSKMEL510.43223.640Details
BioGPS NCI60219487_atSKOV316.34823.640Details
BioGPS NCI60219487_atSN12C28.17823.640Details
BioGPS NCI60219487_atSNB1910.21923.640Details
BioGPS NCI60219487_atSNB7511.09323.640Details
BioGPS NCI60219487_atSR12.75623.640Details
BioGPS NCI60219487_atSW62013.22623.640Details
BioGPS NCI60219487_atT2412.44123.640Details
BioGPS NCI60219487_atT3M415.66723.640Details
BioGPS NCI60219487_atTK1011.86623.640Details
BioGPS NCI60219487_atU11827.39023.640Details
BioGPS NCI60219487_atU13855.13323.640Details
BioGPS NCI60219487_atU20S11.18223.640Details
BioGPS NCI60219487_atU25110.35223.640Details
BioGPS NCI60219487_atU8722.64223.640Details
BioGPS NCI60219487_atUACC25710.27323.640Details
BioGPS NCI60219487_atUACC6216.20723.640Details
BioGPS NCI60219487_atUO319.90823.640Details
BioGPS NCI60219487_atZR75_116.24123.640Details
BioGPS NCI60219487_atastrocytes16.50023.640Details
BioGPS NCI60219487_athuh-713.08623.640Details