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Gene ID: 8815 | BANF1 Antibody Resource


BANF1 Antibody Resource
Gene Full Name: 
barrier to autointegration factor 1
Uniprot: 
O75531
Protein Name: 
barrier-to-autointegration factor
Nucleotide: 
NM_003860
Alias: 
BAF;NGPS;BCRP1;D14S1460;
Ensembl: 
ENSG00000175334
Location: 
11q13.1
HPRD: 
04817
NCBI Gene: 
8815
MIM: 
603811

Summary: 
The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Jan 2009]
Function: 
Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD.
Subcellular location: 
Nucleus. Cytoplasm. Chromosome. Note: Significantly enriched at the nuclear inner membrane, diffusely throughout the nucleus during interphase and concentrated at the chromosomes during the M-phase. May be included in HIV-1 virions via its interaction with viral GAG polyprotein. The phosphorylated form (by VRK1) shows a cytoplasmic localization.
PTM: 
Acetylation;
Disease: 
Nestor-Guillermo progeria syndrome (NGPS) [MIM:614008]: An atypical progeroid syndrome characterized by normal development in the first years of life, later followed by the emergence of generalized lipoatrophy, severe osteoporosis, and marked osteolysis. The atrophic facial subcutaneous fat pad and the marked osteolysis of the maxilla and mandible result in a typical pseudosenile facial appearance with micrognathia, prominent subcutaneous venous patterning, a convex nasal ridge, and proptosis. Cognitive development is completely normal. Patients do not have cardiovascular dysfunction, atherosclerosis, or metabolic anomalies. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAPB00480 BANF1 Antibody (OAPB00480) Polyclonal Human; Mouse ELISA, WB, IF 0.1 mg $355 Details
Polyclonal Antibody OAPB00481 BANF1 Antibody (0.1 mg) Polyclonal ELISA, WB, IF 0.1 mg $355 Details
Polyclonal Antibody ARP64252_P050 BANF1 Antibody - middle region (ARP64252_P050) Human WB 50ug $289 Details
Polyclonal Antibody OAAB10369 BANF1 antibody - center region (OAAB10369) Human WB, IHC 400ul $289 Details

Show all BANF1 antibodies


Product Images
BANF1 Antibody - middle region (ARP64252_P050) in Human MCF-7 cells using Western Blot

Sample Type: Human MCF-7

BANF1 antibody - center region (OAAB10369) in Human colon cells using Immunohistochemistry

Sample Type: Human colon

BANF1 antibody - center region (OAAB10369) in Jurkat cells using Western Blot

Sample Type: Jurkat

BANF1 Antibody (OAPB00480) in human kidney cells using Western Blot

Sample Type: human kidney

BANF1 Antibody (OAPB00480) in human kidney cells using Immunofluorescence

Sample Type: human kidney


BANF1 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP64252 Bovine BANF1 antibody; Bos taurus BANF1 antibody P61283 100.0%
ARP64252 Cat BANF1 antibody; Felis catus BANF1 antibody M3WIK4 100.0%
ARP64252 Chimpanzee BANF1 antibody; Pan troglodytes BANF1 antibody K7DIQ8 100.0%
ARP64252 Chimpanzee BANF1 antibody; Pan troglodytes BANF1 antibody H2Q453 93.0%
ARP64252 Dog BANF1 antibody; Canis familiaris BANF1 antibody E2RGE0 100.0%
ARP64252 Giant panda BANF1 antibody; Ailuropoda melanoleuca BANF1 antibody D2H4N2 100.0%
ARP64252 Giant panda BANF1 antibody; Ailuropoda melanoleuca BANF1 antibody D3JYS2 100.0%
ARP64252 Goat BANF1 antibody; Capra hircus BANF1 antibody G1DGC1 100.0%
ARP64252 Gray short-tailed opossum BANF1 antibody; Monodelphis domestica BANF1 antibody F7GCP3 100.0%
ARP64252 Horse BANF1 antibody; Equus caballus BANF1 antibody F6YEV8 100.0%
ARP64252 Human BANF1 antibody; Homo sapiens BANF1 antibody O75531 100.0%
ARP64252 Mouse BANF1 antibody; Mus musculus BANF1 antibody O54962 100.0%
ARP64252 Rabbit BANF1 antibody; Oryctolagus cuniculus BANF1 antibody G1TA37 100.0%
ARP64252 Rat BANF1 antibody; Rattus norvegicus BANF1 antibody Q9R1T1 100.0%
ARP64252 Rhesus macaque BANF1 antibody; Macaca mulatta BANF1 antibody F6T830 100.0%
ARP64252 Rhesus macaque BANF1 antibody; Macaca mulatta BANF1 antibody F7HQ28 100.0%
ARP64252 Small-eared galago BANF1 antibody; Otolemur garnettii BANF1 antibody H0XFJ9 100.0%
ARP64252 Sumatran orangutan BANF1 antibody; Pongo abelii BANF1 antibody Q5RBU9 100.0%
ARP64252 Tasmanian devil BANF1 antibody; Sarcophilus harrisii BANF1 antibody G3VH58 86.0%
ARP64252 Thirteen-lined ground squirrel BANF1 antibody; Spermophilus tridecemlineatus BANF1 antibody I3MB16 100.0%
ARP64252 Western clawed frog BANF1 antibody; Xenopus tropicalis BANF1 antibody F6X821 93.0%
ARP64252 White-tufted-ear marmoset BANF1 antibody; Callithrix jacchus BANF1 antibody F7FG18 100.0%
ARP64252 White-tufted-ear marmoset BANF1 antibody; Callithrix jacchus BANF1 antibody U3DBV0 100.0%
ARP64252 Zebrafish BANF1 antibody; Danio rerio BANF1 antibody Q6P026 91.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas210125_s_at721_B_lymphoblasts1228.300158.300Details
BioGPS Gene Atlas210125_s_atAdipocyte78.800158.300Details
BioGPS Gene Atlas210125_s_atAdrenalCortex63.750158.300Details
BioGPS Gene Atlas210125_s_atAdrenalgland109.350158.300Details
BioGPS Gene Atlas210125_s_atAmygdala57.350158.300Details
BioGPS Gene Atlas210125_s_atAppendix32.700158.300Details
BioGPS Gene Atlas210125_s_atAtrioventricularNode19.850158.300Details
BioGPS Gene Atlas210125_s_atBDCA4+_DentriticCells249.900158.300Details
BioGPS Gene Atlas210125_s_atBonemarrow40.500158.300Details
BioGPS Gene Atlas210125_s_atBronchialEpithelialCells375.900158.300Details
BioGPS Gene Atlas210125_s_atCD105+_Endothelial578.000158.300Details
BioGPS Gene Atlas210125_s_atCD14+_Monocytes312.350158.300Details
BioGPS Gene Atlas210125_s_atCD19+_BCells(neg._sel.)207.250158.300Details
BioGPS Gene Atlas210125_s_atCD33+_Myeloid257.150158.300Details
BioGPS Gene Atlas210125_s_atCD34+799.500158.300Details
BioGPS Gene Atlas210125_s_atCD4+_Tcells323.200158.300Details
BioGPS Gene Atlas210125_s_atCD56+_NKCells434.700158.300Details
BioGPS Gene Atlas210125_s_atCD71+_EarlyErythroid153.350158.300Details
BioGPS Gene Atlas210125_s_atCD8+_Tcells244.950158.300Details
BioGPS Gene Atlas210125_s_atCardiacMyocytes206.900158.300Details
BioGPS Gene Atlas210125_s_atCaudatenucleus53.750158.300Details
BioGPS Gene Atlas210125_s_atCerebellum115.100158.300Details
BioGPS Gene Atlas210125_s_atCerebellumPeduncles139.550158.300Details
BioGPS Gene Atlas210125_s_atCiliaryGanglion13.800158.300Details
BioGPS Gene Atlas210125_s_atCingulateCortex44.600158.300Details
BioGPS Gene Atlas210125_s_atColorectaladenocarcinoma272.450158.300Details
BioGPS Gene Atlas210125_s_atDorsalRootGanglion27.350158.300Details
BioGPS Gene Atlas210125_s_atFetalThyroid144.950158.300Details
BioGPS Gene Atlas210125_s_atFetalbrain133.800158.300Details
BioGPS Gene Atlas210125_s_atFetalliver53.250158.300Details
BioGPS Gene Atlas210125_s_atFetallung145.950158.300Details
BioGPS Gene Atlas210125_s_atGlobusPallidus27.450158.300Details
BioGPS Gene Atlas210125_s_atHeart254.800158.300Details
BioGPS Gene Atlas210125_s_atHypothalamus81.200158.300Details
BioGPS Gene Atlas210125_s_atKidney32.000158.300Details
BioGPS Gene Atlas210125_s_atLeukemia_chronicMyelogenousK-562198.100158.300Details
BioGPS Gene Atlas210125_s_atLeukemia_promyelocytic-HL-60277.800158.300Details
BioGPS Gene Atlas210125_s_atLeukemialymphoblastic(MOLT-4)272.950158.300Details
BioGPS Gene Atlas210125_s_atLiver42.300158.300Details
BioGPS Gene Atlas210125_s_atLung87.150158.300Details
BioGPS Gene Atlas210125_s_atLymphnode114.300158.300Details
BioGPS Gene Atlas210125_s_atLymphoma_burkitts(Daudi)398.000158.300Details
BioGPS Gene Atlas210125_s_atLymphoma_burkitts(Raji)69.900158.300Details
BioGPS Gene Atlas210125_s_atMedullaOblongata77.700158.300Details
BioGPS Gene Atlas210125_s_atOccipitalLobe72.950158.300Details
BioGPS Gene Atlas210125_s_atOlfactoryBulb135.550158.300Details
BioGPS Gene Atlas210125_s_atOvary21.550158.300Details
BioGPS Gene Atlas210125_s_atPancreas47.150158.300Details
BioGPS Gene Atlas210125_s_atPancreaticIslet51.750158.300Details
BioGPS Gene Atlas210125_s_atParietalLobe58.800158.300Details
BioGPS Gene Atlas210125_s_atPituitary94.450158.300Details
BioGPS Gene Atlas210125_s_atPlacenta149.850158.300Details
BioGPS Gene Atlas210125_s_atPons38.700158.300Details
BioGPS Gene Atlas210125_s_atPrefrontalCortex133.100158.300Details
BioGPS Gene Atlas210125_s_atProstate51.550158.300Details
BioGPS Gene Atlas210125_s_atSalivarygland23.900158.300Details
BioGPS Gene Atlas210125_s_atSkeletalMuscle144.400158.300Details
BioGPS Gene Atlas210125_s_atSkin20.750158.300Details
BioGPS Gene Atlas210125_s_atSmoothMuscle183.100158.300Details
BioGPS Gene Atlas210125_s_atSpinalcord133.300158.300Details
BioGPS Gene Atlas210125_s_atSubthalamicNucleus37.750158.300Details
BioGPS Gene Atlas210125_s_atSuperiorCervicalGanglion13.000158.300Details
BioGPS Gene Atlas210125_s_atTemporalLobe86.950158.300Details
BioGPS Gene Atlas210125_s_atTestis148.350158.300Details
BioGPS Gene Atlas210125_s_atTestisGermCell162.400158.300Details
BioGPS Gene Atlas210125_s_atTestisIntersitial39.350158.300Details
BioGPS Gene Atlas210125_s_atTestisLeydigCell67.950158.300Details
BioGPS Gene Atlas210125_s_atTestisSeminiferousTubule96.700158.300Details
BioGPS Gene Atlas210125_s_atThalamus59.500158.300Details
BioGPS Gene Atlas210125_s_atThymus290.700158.300Details
BioGPS Gene Atlas210125_s_atThyroid97.350158.300Details
BioGPS Gene Atlas210125_s_atTongue40.350158.300Details
BioGPS Gene Atlas210125_s_atTonsil101.850158.300Details
BioGPS Gene Atlas210125_s_atTrachea54.500158.300Details
BioGPS Gene Atlas210125_s_atTrigeminalGanglion40.050158.300Details
BioGPS Gene Atlas210125_s_atUterus68.200158.300Details
BioGPS Gene Atlas210125_s_atUterusCorpus69.100158.300Details
BioGPS Gene Atlas210125_s_atWholeBlood108.850158.300Details
BioGPS Gene Atlas210125_s_atWholebrain122.500158.300Details
BioGPS Gene Atlas210125_s_atcolon79.700158.300Details
BioGPS Gene Atlas210125_s_atpineal_day288.860158.300Details
BioGPS Gene Atlas210125_s_atpineal_night266.880158.300Details
BioGPS Gene Atlas210125_s_atretina202.950158.300Details
BioGPS Gene Atlas210125_s_atsmall_intestine137.150158.300Details
BioGPS NCI60210125_s_at7861689.8452041.620Details
BioGPS NCI60210125_s_atA1721808.6742041.620Details
BioGPS NCI60210125_s_atA2041211.0312041.620Details
BioGPS NCI60210125_s_atA3611020.7992041.620Details
BioGPS NCI60210125_s_atA4981027.1502041.620Details
BioGPS NCI60210125_s_atA5491949.4972041.620Details
BioGPS NCI60210125_s_atACC32567.1982041.620Details
BioGPS NCI60210125_s_atACHN1774.3502041.620Details
BioGPS NCI60210125_s_atALVA311377.7192041.620Details
BioGPS NCI60210125_s_atCAKI11057.0472041.620Details
BioGPS NCI60210125_s_atCCRT CEM1391.4472041.620Details
BioGPS NCI60210125_s_atCOLO205968.3842041.620Details
BioGPS NCI60210125_s_atDLD12412.3812041.620Details
BioGPS NCI60210125_s_atDU1454046.5152041.620Details
BioGPS NCI60210125_s_atEKVX5986.0132041.620Details
BioGPS NCI60210125_s_atGM133990.7082041.620Details
BioGPS NCI60210125_s_atGM1600963.6022041.620Details
BioGPS NCI60210125_s_atGM2313930.4072041.620Details
BioGPS NCI60210125_s_atGM23451156.6002041.620Details
BioGPS NCI60210125_s_atGM24931825.4982041.620Details
BioGPS NCI60210125_s_atGM971410.9782041.620Details
BioGPS NCI60210125_s_atHCC29981720.1502041.620Details
BioGPS NCI60210125_s_atHCT1162741.0522041.620Details
BioGPS NCI60210125_s_atHCT151481.8052041.620Details
BioGPS NCI60210125_s_atHEK 293 T-rex1234.6002041.620Details
BioGPS NCI60210125_s_atHEK 293T1589.7802041.620Details
BioGPS NCI60210125_s_atHEK2931085.6382041.620Details
BioGPS NCI60210125_s_atHELA2535.1232041.620Details
BioGPS NCI60210125_s_atHEPG21246.8502041.620Details
BioGPS NCI60210125_s_atHL601527.4132041.620Details
BioGPS NCI60210125_s_atHOP622398.3332041.620Details
BioGPS NCI60210125_s_atHOP92856.2922041.620Details
BioGPS NCI60210125_s_atHS578T3674.9122041.620Details
BioGPS NCI60210125_s_atHSG3266.3232041.620Details
BioGPS NCI60210125_s_atHT10801581.3792041.620Details
BioGPS NCI60210125_s_atHT292295.1732041.620Details
BioGPS NCI60210125_s_atIGROV13093.2322041.620Details
BioGPS NCI60210125_s_atIOSE802931.9872041.620Details
BioGPS NCI60210125_s_atJURKAT1815.9112041.620Details
BioGPS NCI60210125_s_atK562987.5942041.620Details
BioGPS NCI60210125_s_atKM122270.2602041.620Details
BioGPS NCI60210125_s_atLN183027.0162041.620Details
BioGPS NCI60210125_s_atLNCAP1775.1882041.620Details
BioGPS NCI60210125_s_atLOX IMVI2260.2102041.620Details
BioGPS NCI60210125_s_atM142061.5902041.620Details
BioGPS NCI60210125_s_atMALME 3M390.6102041.620Details
BioGPS NCI60210125_s_atMCF73730.5752041.620Details
BioGPS NCI60210125_s_atMD MB2312908.7292041.620Details
BioGPS NCI60210125_s_atMDA MB4352059.6292041.620Details
BioGPS NCI60210125_s_atMOLT42332.4152041.620Details
BioGPS NCI60210125_s_atNCI 460845.4092041.620Details
BioGPS NCI60210125_s_atNCI H2262036.7792041.620Details
BioGPS NCI60210125_s_atNCI H231167.1802041.620Details
BioGPS NCI60210125_s_atNCI H322M2029.0472041.620Details
BioGPS NCI60210125_s_atNCVADR RES2403.3732041.620Details
BioGPS NCI60210125_s_atOVCAR33581.9252041.620Details
BioGPS NCI60210125_s_atOVCAR41766.5512041.620Details
BioGPS NCI60210125_s_atOVCAR51544.1492041.620Details
BioGPS NCI60210125_s_atOVCAR84067.7232041.620Details
BioGPS NCI60210125_s_atPANC13633.6882041.620Details
BioGPS NCI60210125_s_atRL71087.2622041.620Details
BioGPS NCI60210125_s_atRPMI 82264483.8322041.620Details
BioGPS NCI60210125_s_atRS118461592.3832041.620Details
BioGPS NCI60210125_s_atRXF3936672.7712041.620Details
BioGPS NCI60210125_s_atSAOS21347.6352041.620Details
BioGPS NCI60210125_s_atSF2682648.9902041.620Details
BioGPS NCI60210125_s_atSF295520.6832041.620Details
BioGPS NCI60210125_s_atSF5392337.7222041.620Details
BioGPS NCI60210125_s_atSHSYSY+RA2394.1382041.620Details
BioGPS NCI60210125_s_atSHSYSY-RA1590.5662041.620Details
BioGPS NCI60210125_s_atSKMEL2569.3662041.620Details
BioGPS NCI60210125_s_atSKMEL28168.3212041.620Details
BioGPS NCI60210125_s_atSKMEL51032.0502041.620Details
BioGPS NCI60210125_s_atSKOV31273.7052041.620Details
BioGPS NCI60210125_s_atSN12C3400.9532041.620Details
BioGPS NCI60210125_s_atSNB191747.3652041.620Details
BioGPS NCI60210125_s_atSNB751416.4352041.620Details
BioGPS NCI60210125_s_atSR2034.9652041.620Details
BioGPS NCI60210125_s_atSW6202580.7062041.620Details
BioGPS NCI60210125_s_atT243149.4872041.620Details
BioGPS NCI60210125_s_atT3M41722.3092041.620Details
BioGPS NCI60210125_s_atTK101244.8512041.620Details
BioGPS NCI60210125_s_atU1182706.8182041.620Details
BioGPS NCI60210125_s_atU1383139.1282041.620Details
BioGPS NCI60210125_s_atU20S2755.8142041.620Details
BioGPS NCI60210125_s_atU2512181.9422041.620Details
BioGPS NCI60210125_s_atU872622.4772041.620Details
BioGPS NCI60210125_s_atUACC2571342.7362041.620Details
BioGPS NCI60210125_s_atUACC621073.9352041.620Details
BioGPS NCI60210125_s_atUO313147.0782041.620Details
BioGPS NCI60210125_s_atZR75_12378.0112041.620Details
BioGPS NCI60210125_s_atastrocytes1372.6602041.620Details
BioGPS NCI60210125_s_athuh-71210.5142041.620Details