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Gene ID: 566 | AZU1 Antibody Resource


AZU1 Antibody Resource
Gene Full Name: 
azurocidin 1
Uniprot: 
P20160
Protein Name: 
azurocidin
Nucleotide: 
NM_001700
Alias: 
AZU;HBP;NAZC;AZAMP;CAP37;HUMAZUR;
Ensembl: 
ENSG00000172232
Location: 
19p13.3
HPRD: 
01221
NCBI Gene: 
566
MIM: 
162815

Summary: 
Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Jul 2008]
Function: 
This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G.
Subcellular location: 
Cytoplasmic granule. Note: Cytoplasmic granules of neutrophils.
PTM: 
Disulfide bond;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Protein OPMA04351 Human Azurocidin Protein (0.2mg) Human 0.2mg $340 Details
Polyclonal Antibody ARP66731_P050 AZU1 Antibody (ARP66731_P050) Polyclonal Human Not tested 50 ug $125 Details
Polyclonal Antibody ARP66732_P050 AZU1 Antibody (ARP66732_P050) Polyclonal Bovine, Human Not tested 50 ug $125 Details
Polyclonal Antibody OAAB11305 AZU1 antibody - center region (OAAB11305) Human WB 400ul $289 Details
Polyclonal Antibody ARP73078_P050 AZU1 Antibody - middle region (ARP73078_P050) Human WB 50ug $289 Details

Show all AZU1 antibodies


Product Images
AZU1 Antibody - middle region (ARP73078_P050) in Human HT1080 cells using Western Blot

Sample Type: Human HT1080

AZU1 antibody - center region (OAAB11305) in 293 cells using Western Blot

Sample Type: 293

AZU1 antibody - center region (OAAB11305) in WiDr cells using Western Blot

Sample Type: WiDr


AZU1 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP73078 Bovine AZU1 antibody; Bos taurus AZU1 antibody G3N0Q8 100.0%
ARP73078 Bovine AZU1 antibody; Bos taurus AZU1 antibody G3N2H4 100.0%
ARP66732 Bovine AZU1 antibody; Bos taurus AZU1 antibody G3N0Q8 86.0%
ARP66732 Bovine AZU1 antibody; Bos taurus AZU1 antibody G3N2H4 86.0%
ARP66731 Chimpanzee AZU1 antibody; Pan troglodytes AZU1 antibody H2QET5 100.0%
ARP66732 Chimpanzee AZU1 antibody; Pan troglodytes AZU1 antibody H2QET5 100.0%
ARP73078 Chimpanzee AZU1 antibody; Pan troglodytes AZU1 antibody H2QET5 100.0%
ARP66731 Human AZU1 antibody; Homo sapiens AZU1 antibody P20160 100.0%
ARP66732 Human AZU1 antibody; Homo sapiens AZU1 antibody P20160 100.0%
ARP73078 Human AZU1 antibody; Homo sapiens AZU1 antibody P20160 100.0%
ARP66731 Human AZU1 antibody; Homo sapiens AZU1 antibody Q86SR2 100.0%
ARP66732 Human AZU1 antibody; Homo sapiens AZU1 antibody Q86SR2 100.0%
ARP73078 Human AZU1 antibody; Homo sapiens AZU1 antibody Q86SR2 100.0%
ARP66731 Small-eared galago AZU1 antibody; Otolemur garnettii AZU1 antibody H0WQL2 86.0%
ARP73078 Small-eared galago AZU1 antibody; Otolemur garnettii AZU1 antibody H0WQL2 85.0%
ARP66732 Sumatran orangutan AZU1 antibody; Pongo abelii AZU1 antibody H2NWR4 100.0%
ARP73078 Sumatran orangutan AZU1 antibody; Pongo abelii AZU1 antibody H2NWR4 100.0%
ARP66731 Sumatran orangutan AZU1 antibody; Pongo abelii AZU1 antibody H2NWR4 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas214575_s_at721_B_lymphoblasts5.30042.080Details
BioGPS Gene Atlas214575_s_atAdipocyte4.35042.080Details
BioGPS Gene Atlas214575_s_atAdrenalCortex4.70042.080Details
BioGPS Gene Atlas214575_s_atAdrenalgland3.70042.080Details
BioGPS Gene Atlas214575_s_atAmygdala4.40042.080Details
BioGPS Gene Atlas214575_s_atAppendix4.80042.080Details
BioGPS Gene Atlas214575_s_atAtrioventricularNode3.90042.080Details
BioGPS Gene Atlas214575_s_atBDCA4+_DentriticCells4.65042.080Details
BioGPS Gene Atlas214575_s_atBonemarrow2393.60042.080Details
BioGPS Gene Atlas214575_s_atBronchialEpithelialCells4.30042.080Details
BioGPS Gene Atlas214575_s_atCD105+_Endothelial4.40042.080Details
BioGPS Gene Atlas214575_s_atCD14+_Monocytes4.65042.080Details
BioGPS Gene Atlas214575_s_atCD19+_BCells(neg._sel.)4.70042.080Details
BioGPS Gene Atlas214575_s_atCD33+_Myeloid161.85042.080Details
BioGPS Gene Atlas214575_s_atCD34+768.15042.080Details
BioGPS Gene Atlas214575_s_atCD4+_Tcells4.70042.080Details
BioGPS Gene Atlas214575_s_atCD56+_NKCells5.10042.080Details
BioGPS Gene Atlas214575_s_atCD71+_EarlyErythroid4.15042.080Details
BioGPS Gene Atlas214575_s_atCD8+_Tcells4.20042.080Details
BioGPS Gene Atlas214575_s_atCardiacMyocytes5.80042.080Details
BioGPS Gene Atlas214575_s_atCaudatenucleus3.90042.080Details
BioGPS Gene Atlas214575_s_atCerebellum3.55042.080Details
BioGPS Gene Atlas214575_s_atCerebellumPeduncles5.00042.080Details
BioGPS Gene Atlas214575_s_atCiliaryGanglion3.15042.080Details
BioGPS Gene Atlas214575_s_atCingulateCortex4.50042.080Details
BioGPS Gene Atlas214575_s_atColorectaladenocarcinoma4.40042.080Details
BioGPS Gene Atlas214575_s_atDorsalRootGanglion3.40042.080Details
BioGPS Gene Atlas214575_s_atFetalThyroid4.25042.080Details
BioGPS Gene Atlas214575_s_atFetalbrain4.30042.080Details
BioGPS Gene Atlas214575_s_atFetalliver3.85042.080Details
BioGPS Gene Atlas214575_s_atFetallung8.35042.080Details
BioGPS Gene Atlas214575_s_atGlobusPallidus3.30042.080Details
BioGPS Gene Atlas214575_s_atHeart5.70042.080Details
BioGPS Gene Atlas214575_s_atHypothalamus4.70042.080Details
BioGPS Gene Atlas214575_s_atKidney3.75042.080Details
BioGPS Gene Atlas214575_s_atLeukemia_chronicMyelogenousK-5623.95042.080Details
BioGPS Gene Atlas214575_s_atLeukemia_promyelocytic-HL-603.85042.080Details
BioGPS Gene Atlas214575_s_atLeukemialymphoblastic(MOLT-4)3.50042.080Details
BioGPS Gene Atlas214575_s_atLiver5.90042.080Details
BioGPS Gene Atlas214575_s_atLung4.80042.080Details
BioGPS Gene Atlas214575_s_atLymphnode3.75042.080Details
BioGPS Gene Atlas214575_s_atLymphoma_burkitts(Daudi)5.60042.080Details
BioGPS Gene Atlas214575_s_atLymphoma_burkitts(Raji)6.15042.080Details
BioGPS Gene Atlas214575_s_atMedullaOblongata4.00042.080Details
BioGPS Gene Atlas214575_s_atOccipitalLobe3.95042.080Details
BioGPS Gene Atlas214575_s_atOlfactoryBulb3.45042.080Details
BioGPS Gene Atlas214575_s_atOvary2.95042.080Details
BioGPS Gene Atlas214575_s_atPancreas3.55042.080Details
BioGPS Gene Atlas214575_s_atPancreaticIslet4.70042.080Details
BioGPS Gene Atlas214575_s_atParietalLobe4.70042.080Details
BioGPS Gene Atlas214575_s_atPituitary5.10042.080Details
BioGPS Gene Atlas214575_s_atPlacenta4.45042.080Details
BioGPS Gene Atlas214575_s_atPons4.20042.080Details
BioGPS Gene Atlas214575_s_atPrefrontalCortex5.35042.080Details
BioGPS Gene Atlas214575_s_atProstate5.05042.080Details
BioGPS Gene Atlas214575_s_atSalivarygland3.55042.080Details
BioGPS Gene Atlas214575_s_atSkeletalMuscle5.25042.080Details
BioGPS Gene Atlas214575_s_atSkin3.70042.080Details
BioGPS Gene Atlas214575_s_atSmoothMuscle4.90042.080Details
BioGPS Gene Atlas214575_s_atSpinalcord4.65042.080Details
BioGPS Gene Atlas214575_s_atSubthalamicNucleus4.10042.080Details
BioGPS Gene Atlas214575_s_atSuperiorCervicalGanglion5.05042.080Details
BioGPS Gene Atlas214575_s_atTemporalLobe4.00042.080Details
BioGPS Gene Atlas214575_s_atTestis3.70042.080Details
BioGPS Gene Atlas214575_s_atTestisGermCell3.60042.080Details
BioGPS Gene Atlas214575_s_atTestisIntersitial3.65042.080Details
BioGPS Gene Atlas214575_s_atTestisLeydigCell4.45042.080Details
BioGPS Gene Atlas214575_s_atTestisSeminiferousTubule3.75042.080Details
BioGPS Gene Atlas214575_s_atThalamus4.45042.080Details
BioGPS Gene Atlas214575_s_atThymus3.45042.080Details
BioGPS Gene Atlas214575_s_atThyroid5.40042.080Details
BioGPS Gene Atlas214575_s_atTongue4.85042.080Details
BioGPS Gene Atlas214575_s_atTonsil4.25042.080Details
BioGPS Gene Atlas214575_s_atTrachea3.65042.080Details
BioGPS Gene Atlas214575_s_atTrigeminalGanglion4.45042.080Details
BioGPS Gene Atlas214575_s_atUterus3.55042.080Details
BioGPS Gene Atlas214575_s_atUterusCorpus4.25042.080Details
BioGPS Gene Atlas214575_s_atWholeBlood4.80042.080Details
BioGPS Gene Atlas214575_s_atWholebrain3.60042.080Details
BioGPS Gene Atlas214575_s_atcolon4.35042.080Details
BioGPS Gene Atlas214575_s_atpineal_day5.42042.080Details
BioGPS Gene Atlas214575_s_atpineal_night5.28042.080Details
BioGPS Gene Atlas214575_s_atretina5.27542.080Details
BioGPS Gene Atlas214575_s_atsmall_intestine4.15042.080Details
BioGPS NCI60214575_s_at7864.5674.510Details
BioGPS NCI60214575_s_atA1724.1314.510Details
BioGPS NCI60214575_s_atA2044.5454.510Details
BioGPS NCI60214575_s_atA3614.5294.510Details
BioGPS NCI60214575_s_atA4984.4774.510Details
BioGPS NCI60214575_s_atA5494.5884.510Details
BioGPS NCI60214575_s_atACC34.6994.510Details
BioGPS NCI60214575_s_atACHN4.1904.510Details
BioGPS NCI60214575_s_atALVA314.7694.510Details
BioGPS NCI60214575_s_atCAKI14.9014.510Details
BioGPS NCI60214575_s_atCCRT CEM6.2644.510Details
BioGPS NCI60214575_s_atCOLO2054.5324.510Details
BioGPS NCI60214575_s_atDLD14.3894.510Details
BioGPS NCI60214575_s_atDU1454.2074.510Details
BioGPS NCI60214575_s_atEKVX4.2534.510Details
BioGPS NCI60214575_s_atGM1334.5774.510Details
BioGPS NCI60214575_s_atGM16004.7034.510Details
BioGPS NCI60214575_s_atGM23134.5564.510Details
BioGPS NCI60214575_s_atGM23454.4774.510Details
BioGPS NCI60214575_s_atGM24934.6894.510Details
BioGPS NCI60214575_s_atGM975.0044.510Details
BioGPS NCI60214575_s_atHCC29983.9574.510Details
BioGPS NCI60214575_s_atHCT1164.4794.510Details
BioGPS NCI60214575_s_atHCT154.1514.510Details
BioGPS NCI60214575_s_atHEK 293 T-rex4.7394.510Details
BioGPS NCI60214575_s_atHEK 293T4.4574.510Details
BioGPS NCI60214575_s_atHEK2934.4544.510Details
BioGPS NCI60214575_s_atHELA4.1284.510Details
BioGPS NCI60214575_s_atHEPG24.4704.510Details
BioGPS NCI60214575_s_atHL605.0864.510Details
BioGPS NCI60214575_s_atHOP624.4964.510Details
BioGPS NCI60214575_s_atHOP924.2964.510Details
BioGPS NCI60214575_s_atHS578T4.4024.510Details
BioGPS NCI60214575_s_atHSG4.3144.510Details
BioGPS NCI60214575_s_atHT10804.4594.510Details
BioGPS NCI60214575_s_atHT294.8074.510Details
BioGPS NCI60214575_s_atIGROV14.3804.510Details
BioGPS NCI60214575_s_atIOSE804.4534.510Details
BioGPS NCI60214575_s_atJURKAT4.4674.510Details
BioGPS NCI60214575_s_atK5624.7964.510Details
BioGPS NCI60214575_s_atKM124.8834.510Details
BioGPS NCI60214575_s_atLN184.2134.510Details
BioGPS NCI60214575_s_atLNCAP4.4974.510Details
BioGPS NCI60214575_s_atLOX IMVI4.4644.510Details
BioGPS NCI60214575_s_atM144.4304.510Details
BioGPS NCI60214575_s_atMALME 3M4.7894.510Details
BioGPS NCI60214575_s_atMCF74.3414.510Details
BioGPS NCI60214575_s_atMD MB2314.4944.510Details
BioGPS NCI60214575_s_atMDA MB4355.0414.510Details
BioGPS NCI60214575_s_atMOLT44.6424.510Details
BioGPS NCI60214575_s_atNCI 4604.6814.510Details
BioGPS NCI60214575_s_atNCI H2264.6014.510Details
BioGPS NCI60214575_s_atNCI H234.4824.510Details
BioGPS NCI60214575_s_atNCI H322M4.4754.510Details
BioGPS NCI60214575_s_atNCVADR RES4.2264.510Details
BioGPS NCI60214575_s_atOVCAR34.6544.510Details
BioGPS NCI60214575_s_atOVCAR44.4564.510Details
BioGPS NCI60214575_s_atOVCAR54.4084.510Details
BioGPS NCI60214575_s_atOVCAR84.0204.510Details
BioGPS NCI60214575_s_atPANC14.5944.510Details
BioGPS NCI60214575_s_atRL74.7304.510Details
BioGPS NCI60214575_s_atRPMI 82264.7234.510Details
BioGPS NCI60214575_s_atRS118464.7404.510Details
BioGPS NCI60214575_s_atRXF3934.4494.510Details
BioGPS NCI60214575_s_atSAOS24.5254.510Details
BioGPS NCI60214575_s_atSF2684.4784.510Details
BioGPS NCI60214575_s_atSF2954.3894.510Details
BioGPS NCI60214575_s_atSF5394.2314.510Details
BioGPS NCI60214575_s_atSHSYSY+RA4.3524.510Details
BioGPS NCI60214575_s_atSHSYSY-RA4.4194.510Details
BioGPS NCI60214575_s_atSKMEL24.4604.510Details
BioGPS NCI60214575_s_atSKMEL284.4974.510Details
BioGPS NCI60214575_s_atSKMEL54.2694.510Details
BioGPS NCI60214575_s_atSKOV34.6044.510Details
BioGPS NCI60214575_s_atSN12C4.4384.510Details
BioGPS NCI60214575_s_atSNB194.0644.510Details
BioGPS NCI60214575_s_atSNB754.4644.510Details
BioGPS NCI60214575_s_atSR4.5344.510Details
BioGPS NCI60214575_s_atSW6204.7084.510Details
BioGPS NCI60214575_s_atT244.5524.510Details
BioGPS NCI60214575_s_atT3M44.8714.510Details
BioGPS NCI60214575_s_atTK104.4824.510Details
BioGPS NCI60214575_s_atU1184.3614.510Details
BioGPS NCI60214575_s_atU1384.1074.510Details
BioGPS NCI60214575_s_atU20S4.3284.510Details
BioGPS NCI60214575_s_atU2514.4344.510Details
BioGPS NCI60214575_s_atU874.3114.510Details
BioGPS NCI60214575_s_atUACC2574.4374.510Details
BioGPS NCI60214575_s_atUACC624.5434.510Details
BioGPS NCI60214575_s_atUO314.2394.510Details
BioGPS NCI60214575_s_atZR75_14.7734.510Details
BioGPS NCI60214575_s_atastrocytes4.4714.510Details
BioGPS NCI60214575_s_athuh-74.6754.510Details