Search Antibody, Protein, and ELISA Kit Solutions


Gene ID: 549 | Auh Antibody Resource


Auh Antibody Resource
Gene Full Name: 
AU RNA binding protein/enoyl-CoA hydratase
Uniprot: 
Q13825
Protein Name: 
methylglutaconyl-CoA hydratase, mitochondrial
Nucleotide: 
NM_001698
Alias: 
Ensembl: 
ENSG00000148090
Location: 
9q22.31
HPRD: 
08987
NCBI Gene: 
549
MIM: 
600529

Summary: 
The methylglutaconyl-CoA hydratase, mitochondrial protein binds to the AU-rich element (ARE), a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity. A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92% identity with the human protein. It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein. Human AUH is expressed as a single mRNA species of 1.8 kb, and translated as a 40-kDa precursor protein which is subsequently processed to a 32-kDa mature form. [provided by RefSeq, May 2010]
Function: 
Catalyzes the conversion of 3-methylglutaconyl-CoA to 3-hydroxy-3-methylglutaryl-CoA. Has very low enoyl-CoA hydratase activity. Was originally identified as RNA-binding protein that binds in vitro to clustered 5'-AUUUA-3' motifs.
Subcellular location: 
Mitochondrion.
PTM: 
Acetylation;
Disease: 
3-methylglutaconic aciduria 1 (MGA1) [MIM:250950]: An inborn error of leucine metabolism. It leads to an autosomal recessive syndrome with variable clinical phenotype, ranging from delayed speech development to severe psychomotor retardation, coma, failure to thrive, metabolic acidosis and dystonia. MGA1 can be distinguished from other forms of MGA by the pattern of metabolite excretion: 3-methylglutaconic acid levels are higher than those detected in other forms, whereas methylglutaric acid levels are usually only slightly elevated and there is a high level of 3-hydroxyisovaleric acid excretion (not present in other MGA forms). Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP40374_P050 AUH antibody - C-terminal region (ARP40374_P050) Polyclonal Bovine, Guinea pig, Human, Mouse, Pig, Rabbit, Rat IHC, WB 50ug $289 Details
Polyclonal Antibody ARP40373_P050 Auh antibody - N-terminal region (ARP40373_P050) Polyclonal Bovine, Human, Mouse, Rabbit, Rat WB 50ug $289 Details
Protein OPPA02491 AUH Human - Recombinant Human AU RNA Binding Protein/Enoyl-CoA Hydratase (5ug) 5ug $100 Details
Polyclonal Antibody OAAB00130 AUH antibody - C-terminal region (OAAB00130) Human WB, ELISA 400ul $289 Details

Show all Auh antibodies


Product Images
Auh antibody - N-terminal region (ARP40373_P050) in Mouse Heart cells using Western Blot

Sample Type: Mouse Heart

AUH antibody - C-terminal region (ARP40374_P050) in Human HepG2 cells using Western Blot

Sample Type: Human HepG2

AUH antibody - C-terminal region (ARP40374_P050) in Human Kidney cells using Immunohistochemistry

Sample Type: Human Kidney


Auh Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP40373 African clawed frog Auh antibody; Xenopus laevis Auh antibody Q4V7P4 83.0%
ARP40373 Bovine Auh antibody; Bos taurus Auh antibody A7YSY7 93.0%
ARP40374 Chicken Auh antibody; Gallus gallus Auh antibody E1BTQ9 79.0%
ARP40373 Chimpanzee Auh antibody; Pan troglodytes Auh antibody H2QXF9 100.0%
ARP40374 Chimpanzee Auh antibody; Pan troglodytes Auh antibody H2QXF9 100.0%
ARP40374 Chinese softshell turtle Auh antibody; Pelodiscus sinensis Auh antibody K7FZE0 79.0%
ARP40374 Collared flycatcher Auh antibody; Ficedula albicollis Auh antibody U3JQA6 79.0%
ARP40374 Collared flycatcher Auh antibody; Ficedula albicollis Auh antibody U3JQA7 79.0%
ARP40374 Dog Auh antibody; Canis familiaris Auh antibody J9P2R5 100.0%
ARP40373 Dog Auh antibody; Canis familiaris Auh antibody J9P1A7 93.0%
ARP40373 Dog Auh antibody; Canis familiaris Auh antibody J9P2R5 93.0%
ARP40374 Domestic duck Auh antibody; Anas platyrhynchos Auh antibody U3I6L6 79.0%
ARP40374 European domestic ferret Auh antibody; Mustela putorius furo Auh antibody M3Y641 93.0%
ARP40374 Gray short-tailed opossum Auh antibody; Monodelphis domestica Auh antibody F6QU09 86.0%
ARP40374 Green anole Auh antibody; Anolis carolinensis Auh antibody R4G9Z1 79.0%
ARP40374 Horse Auh antibody; Equus caballus Auh antibody F6RY06 100.0%
ARP40373 Human Auh antibody; Homo sapiens Auh antibody B4DYI6 100.0%
ARP40373 Human Auh antibody; Homo sapiens Auh antibody Q13825-2 100.0%
ARP40374 Human Auh antibody; Homo sapiens Auh antibody Q13825-2 100.0%
ARP40373 Human Auh antibody; Homo sapiens Auh antibody Q13825 100.0%
ARP40374 Human Auh antibody; Homo sapiens Auh antibody Q13825 100.0%
ARP40373 Mouse Auh antibody; Mus musculus Auh antibody E9Q6L3 100.0%
ARP40373 Mouse Auh antibody; Mus musculus Auh antibody E9QMT1 100.0%
ARP40374 Mouse Auh antibody; Mus musculus Auh antibody F6R307 100.0%
ARP40374 Mouse Auh antibody; Mus musculus Auh antibody F6RT60 100.0%
ARP40373 Mouse Auh antibody; Mus musculus Auh antibody Q3TEG5 100.0%
ARP40373 Mouse Auh antibody; Mus musculus Auh antibody Q9JLZ3-2 100.0%
ARP40373 Mouse Auh antibody; Mus musculus Auh antibody Q9JLZ3-3 100.0%
ARP40373 Mouse Auh antibody; Mus musculus Auh antibody Q9JLZ3 100.0%
ARP40374 Mouse Auh antibody; Mus musculus Auh antibody Q9JLZ3 100.0%
ARP40374 Northern white-cheeked gibbon Auh antibody; Nomascus leucogenys Auh antibody G1QHZ0 100.0%
ARP40373 Northern white-cheeked gibbon Auh antibody; Nomascus leucogenys Auh antibody G1QHZ0 93.0%
ARP40373 Pig Auh antibody; Sus scrofa Auh antibody F1RN09 93.0%
ARP40373 Pig Auh antibody; Sus scrofa Auh antibody F1RN10 93.0%
ARP40374 Rabbit Auh antibody; Oryctolagus cuniculus Auh antibody G1ST15 100.0%
ARP40373 Rabbit Auh antibody; Oryctolagus cuniculus Auh antibody G1ST15 93.0%
ARP40373 Rat Auh antibody; Rattus norvegicus Auh antibody F1LU71 100.0%
ARP40374 Rat Auh antibody; Rattus norvegicus Auh antibody F1LU71 100.0%
ARP40373 Rhesus macaque Auh antibody; Macaca mulatta Auh antibody F6U1T8 100.0%
ARP40374 Rhesus macaque Auh antibody; Macaca mulatta Auh antibody F6U1T8 100.0%
ARP40373 Rhesus macaque Auh antibody; Macaca mulatta Auh antibody F7APJ9 100.0%
ARP40374 Rhesus macaque Auh antibody; Macaca mulatta Auh antibody F7APJ9 100.0%
ARP40374 Small-eared galago Auh antibody; Otolemur garnettii Auh antibody H0X5F9 100.0%
ARP40373 Small-eared galago Auh antibody; Otolemur garnettii Auh antibody H0X5F9 93.0%
ARP40374 Sumatran orangutan Auh antibody; Pongo abelii Auh antibody H2PSN0 100.0%
ARP40373 Western clawed frog Auh antibody; Xenopus tropicalis Auh antibody B2GUS5 83.0%
ARP40374 White-tufted-ear marmoset Auh antibody; Callithrix jacchus Auh antibody F7ISC3 100.0%
ARP40374 White-tufted-ear marmoset Auh antibody; Callithrix jacchus Auh antibody F7ISD5 100.0%
ARP40373 White-tufted-ear marmoset Auh antibody; Callithrix jacchus Auh antibody F7E5A1 93.0%
ARP40373 White-tufted-ear marmoset Auh antibody; Callithrix jacchus Auh antibody F7HU24 93.0%
ARP40373 White-tufted-ear marmoset Auh antibody; Callithrix jacchus Auh antibody F7ISC3 93.0%
ARP40373 White-tufted-ear marmoset Auh antibody; Callithrix jacchus Auh antibody F7ISD5 93.0%
ARP40374 Zebra finch Auh antibody; Taeniopygia guttata Auh antibody H0YQ75 79.0%
ARP48829 Zebrafish Auh antibody; Danio rerio Auh antibody F1RDX1 79.0%
ARP48829 Zebrafish Auh antibody; Danio rerio Auh antibody Q6DC25 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas205052_at721_B_lymphoblasts5.85020.290Details
BioGPS Gene Atlas205052_atAdipocyte9.00020.290Details
BioGPS Gene Atlas205052_atAdrenalCortex13.05020.290Details
BioGPS Gene Atlas205052_atAdrenalgland17.65020.290Details
BioGPS Gene Atlas205052_atAmygdala65.95020.290Details
BioGPS Gene Atlas205052_atAppendix9.85020.290Details
BioGPS Gene Atlas205052_atAtrioventricularNode6.35020.290Details
BioGPS Gene Atlas205052_atBDCA4+_DentriticCells13.85020.290Details
BioGPS Gene Atlas205052_atBonemarrow7.55020.290Details
BioGPS Gene Atlas205052_atBronchialEpithelialCells7.75020.290Details
BioGPS Gene Atlas205052_atCD105+_Endothelial9.10020.290Details
BioGPS Gene Atlas205052_atCD14+_Monocytes7.00020.290Details
BioGPS Gene Atlas205052_atCD19+_BCells(neg._sel.)13.75020.290Details
BioGPS Gene Atlas205052_atCD33+_Myeloid8.70020.290Details
BioGPS Gene Atlas205052_atCD34+14.50020.290Details
BioGPS Gene Atlas205052_atCD4+_Tcells12.15020.290Details
BioGPS Gene Atlas205052_atCD56+_NKCells25.55020.290Details
BioGPS Gene Atlas205052_atCD71+_EarlyErythroid11.85020.290Details
BioGPS Gene Atlas205052_atCD8+_Tcells11.45020.290Details
BioGPS Gene Atlas205052_atCardiacMyocytes10.10020.290Details
BioGPS Gene Atlas205052_atCaudatenucleus19.30020.290Details
BioGPS Gene Atlas205052_atCerebellum6.30020.290Details
BioGPS Gene Atlas205052_atCerebellumPeduncles15.40020.290Details
BioGPS Gene Atlas205052_atCiliaryGanglion7.80020.290Details
BioGPS Gene Atlas205052_atCingulateCortex26.60020.290Details
BioGPS Gene Atlas205052_atColorectaladenocarcinoma9.15020.290Details
BioGPS Gene Atlas205052_atDorsalRootGanglion7.95020.290Details
BioGPS Gene Atlas205052_atFetalThyroid22.35020.290Details
BioGPS Gene Atlas205052_atFetalbrain15.30020.290Details
BioGPS Gene Atlas205052_atFetalliver9.55020.290Details
BioGPS Gene Atlas205052_atFetallung25.85020.290Details
BioGPS Gene Atlas205052_atGlobusPallidus7.05020.290Details
BioGPS Gene Atlas205052_atHeart10.65020.290Details
BioGPS Gene Atlas205052_atHypothalamus78.15020.290Details
BioGPS Gene Atlas205052_atKidney29.10020.290Details
BioGPS Gene Atlas205052_atLeukemia_chronicMyelogenousK-5628.45020.290Details
BioGPS Gene Atlas205052_atLeukemia_promyelocytic-HL-607.55020.290Details
BioGPS Gene Atlas205052_atLeukemialymphoblastic(MOLT-4)6.45020.290Details
BioGPS Gene Atlas205052_atLiver10.30020.290Details
BioGPS Gene Atlas205052_atLung8.60020.290Details
BioGPS Gene Atlas205052_atLymphnode7.85020.290Details
BioGPS Gene Atlas205052_atLymphoma_burkitts(Daudi)9.25020.290Details
BioGPS Gene Atlas205052_atLymphoma_burkitts(Raji)10.85020.290Details
BioGPS Gene Atlas205052_atMedullaOblongata18.70020.290Details
BioGPS Gene Atlas205052_atOccipitalLobe19.45020.290Details
BioGPS Gene Atlas205052_atOlfactoryBulb8.35020.290Details
BioGPS Gene Atlas205052_atOvary5.20020.290Details
BioGPS Gene Atlas205052_atPancreas7.90020.290Details
BioGPS Gene Atlas205052_atPancreaticIslet9.45020.290Details
BioGPS Gene Atlas205052_atParietalLobe19.60020.290Details
BioGPS Gene Atlas205052_atPituitary15.95020.290Details
BioGPS Gene Atlas205052_atPlacenta15.95020.290Details
BioGPS Gene Atlas205052_atPons16.15020.290Details
BioGPS Gene Atlas205052_atPrefrontalCortex49.10020.290Details
BioGPS Gene Atlas205052_atProstate80.05020.290Details
BioGPS Gene Atlas205052_atSalivarygland23.70020.290Details
BioGPS Gene Atlas205052_atSkeletalMuscle10.25020.290Details
BioGPS Gene Atlas205052_atSkin6.60020.290Details
BioGPS Gene Atlas205052_atSmoothMuscle7.80020.290Details
BioGPS Gene Atlas205052_atSpinalcord16.80020.290Details
BioGPS Gene Atlas205052_atSubthalamicNucleus18.40020.290Details
BioGPS Gene Atlas205052_atSuperiorCervicalGanglion10.60020.290Details
BioGPS Gene Atlas205052_atTemporalLobe12.80020.290Details
BioGPS Gene Atlas205052_atTestis5.75020.290Details
BioGPS Gene Atlas205052_atTestisGermCell7.25020.290Details
BioGPS Gene Atlas205052_atTestisIntersitial6.10020.290Details
BioGPS Gene Atlas205052_atTestisLeydigCell7.55020.290Details
BioGPS Gene Atlas205052_atTestisSeminiferousTubule7.15020.290Details
BioGPS Gene Atlas205052_atThalamus48.55020.290Details
BioGPS Gene Atlas205052_atThymus5.30020.290Details
BioGPS Gene Atlas205052_atThyroid73.35020.290Details
BioGPS Gene Atlas205052_atTongue8.70020.290Details
BioGPS Gene Atlas205052_atTonsil7.70020.290Details
BioGPS Gene Atlas205052_atTrachea7.30020.290Details
BioGPS Gene Atlas205052_atTrigeminalGanglion11.80020.290Details
BioGPS Gene Atlas205052_atUterus8.10020.290Details
BioGPS Gene Atlas205052_atUterusCorpus8.15020.290Details
BioGPS Gene Atlas205052_atWholeBlood9.95020.290Details
BioGPS Gene Atlas205052_atWholebrain28.00020.290Details
BioGPS Gene Atlas205052_atcolon26.45020.290Details
BioGPS Gene Atlas205052_atpineal_day95.60020.290Details
BioGPS Gene Atlas205052_atpineal_night89.54020.290Details
BioGPS Gene Atlas205052_atretina11.57520.290Details
BioGPS Gene Atlas205052_atsmall_intestine8.95020.290Details
BioGPS NCI60205052_at786153.385173.560Details
BioGPS NCI60205052_atA172337.293173.560Details
BioGPS NCI60205052_atA20442.321173.560Details
BioGPS NCI60205052_atA361382.570173.560Details
BioGPS NCI60205052_atA49861.961173.560Details
BioGPS NCI60205052_atA549184.438173.560Details
BioGPS NCI60205052_atACC379.143173.560Details
BioGPS NCI60205052_atACHN66.144173.560Details
BioGPS NCI60205052_atALVA3186.743173.560Details
BioGPS NCI60205052_atCAKI1180.018173.560Details
BioGPS NCI60205052_atCCRT CEM50.935173.560Details
BioGPS NCI60205052_atCOLO205254.116173.560Details
BioGPS NCI60205052_atDLD1234.300173.560Details
BioGPS NCI60205052_atDU14559.468173.560Details
BioGPS NCI60205052_atEKVX378.144173.560Details
BioGPS NCI60205052_atGM133268.122173.560Details
BioGPS NCI60205052_atGM1600145.883173.560Details
BioGPS NCI60205052_atGM231376.680173.560Details
BioGPS NCI60205052_atGM2345196.977173.560Details
BioGPS NCI60205052_atGM2493103.791173.560Details
BioGPS NCI60205052_atGM97155.795173.560Details
BioGPS NCI60205052_atHCC2998419.587173.560Details
BioGPS NCI60205052_atHCT116345.502173.560Details
BioGPS NCI60205052_atHCT151031.394173.560Details
BioGPS NCI60205052_atHEK 293 T-rex72.377173.560Details
BioGPS NCI60205052_atHEK 293T495.642173.560Details
BioGPS NCI60205052_atHEK293239.349173.560Details
BioGPS NCI60205052_atHELA128.708173.560Details
BioGPS NCI60205052_atHEPG2675.048173.560Details
BioGPS NCI60205052_atHL6061.431173.560Details
BioGPS NCI60205052_atHOP62163.288173.560Details
BioGPS NCI60205052_atHOP92154.506173.560Details
BioGPS NCI60205052_atHS578T14.407173.560Details
BioGPS NCI60205052_atHSG66.179173.560Details
BioGPS NCI60205052_atHT108074.582173.560Details
BioGPS NCI60205052_atHT29121.722173.560Details
BioGPS NCI60205052_atIGROV1401.911173.560Details
BioGPS NCI60205052_atIOSE8042.703173.560Details
BioGPS NCI60205052_atJURKAT26.702173.560Details
BioGPS NCI60205052_atK56247.300173.560Details
BioGPS NCI60205052_atKM1259.705173.560Details
BioGPS NCI60205052_atLN18161.710173.560Details
BioGPS NCI60205052_atLNCAP251.618173.560Details
BioGPS NCI60205052_atLOX IMVI68.013173.560Details
BioGPS NCI60205052_atM1445.489173.560Details
BioGPS NCI60205052_atMALME 3M29.047173.560Details
BioGPS NCI60205052_atMCF748.320173.560Details
BioGPS NCI60205052_atMD MB23143.513173.560Details
BioGPS NCI60205052_atMDA MB435177.740173.560Details
BioGPS NCI60205052_atMOLT457.660173.560Details
BioGPS NCI60205052_atNCI 46082.205173.560Details
BioGPS NCI60205052_atNCI H22632.352173.560Details
BioGPS NCI60205052_atNCI H23281.925173.560Details
BioGPS NCI60205052_atNCI H322M92.608173.560Details
BioGPS NCI60205052_atNCVADR RES29.360173.560Details
BioGPS NCI60205052_atOVCAR344.985173.560Details
BioGPS NCI60205052_atOVCAR428.704173.560Details
BioGPS NCI60205052_atOVCAR598.955173.560Details
BioGPS NCI60205052_atOVCAR8147.918173.560Details
BioGPS NCI60205052_atPANC188.793173.560Details
BioGPS NCI60205052_atRL751.464173.560Details
BioGPS NCI60205052_atRPMI 8226237.868173.560Details
BioGPS NCI60205052_atRS1184651.318173.560Details
BioGPS NCI60205052_atRXF39329.538173.560Details
BioGPS NCI60205052_atSAOS277.385173.560Details
BioGPS NCI60205052_atSF268105.072173.560Details
BioGPS NCI60205052_atSF29532.915173.560Details
BioGPS NCI60205052_atSF53941.226173.560Details
BioGPS NCI60205052_atSHSYSY+RA64.842173.560Details
BioGPS NCI60205052_atSHSYSY-RA111.454173.560Details
BioGPS NCI60205052_atSKMEL231.674173.560Details
BioGPS NCI60205052_atSKMEL28112.326173.560Details
BioGPS NCI60205052_atSKMEL5462.785173.560Details
BioGPS NCI60205052_atSKOV3127.794173.560Details
BioGPS NCI60205052_atSN12C510.958173.560Details
BioGPS NCI60205052_atSNB19144.052173.560Details
BioGPS NCI60205052_atSNB7544.616173.560Details
BioGPS NCI60205052_atSR652.821173.560Details
BioGPS NCI60205052_atSW62074.566173.560Details
BioGPS NCI60205052_atT2444.525173.560Details
BioGPS NCI60205052_atT3M4619.921173.560Details
BioGPS NCI60205052_atTK10198.726173.560Details
BioGPS NCI60205052_atU118219.910173.560Details
BioGPS NCI60205052_atU138137.425173.560Details
BioGPS NCI60205052_atU20S53.912173.560Details
BioGPS NCI60205052_atU25121.746173.560Details
BioGPS NCI60205052_atU87660.045173.560Details
BioGPS NCI60205052_atUACC25750.247173.560Details
BioGPS NCI60205052_atUACC6225.623173.560Details
BioGPS NCI60205052_atUO3138.686173.560Details
BioGPS NCI60205052_atZR75_148.235173.560Details
BioGPS NCI60205052_atastrocytes45.812173.560Details
BioGPS NCI60205052_athuh-7259.632173.560Details