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Gene ID: 525 | Atp6v1b1 Antibody Resource


Atp6v1b1 Antibody Resource
Gene Full Name: 
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
Uniprot: 
P15313
Protein Name: 
V-type proton ATPase subunit B, kidney isoform
Nucleotide: 
NM_001692
Alias: 
VATB;VMA2;VPP3;RTA1B;ATP6B1;
Ensembl: 
ENSG00000116039
Location: 
2p13.1
HPRD: 
01887
NCBI Gene: 
525
MIM: 
192132

Summary: 
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. [provided by RefSeq, Jul 2008]
Function: 
Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Subcellular location: 
Endomembrane system; Peripheral membrane protein. Note: Endomembrane.
PTM: 
Disease: 
Renal tubular acidosis, distal, with progressive nerve deafness (dRTA-D) [MIM:267300]: An autosomal recessive disease characterized by the association of renal distal tubular acidosis with sensorineural hearing loss. Distal renal tubular acidosis is characterized by reduced ability to acidify urine, variable hyperchloremic hypokalemic metabolic acidosis, nephrocalcinosis, and nephrolithiasis. It is due to functional failure of alpha-intercalated cells of the cortical collecting duct of the distal nephron, where vectorial proton transport is required for urinary acidification. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP56327_P050 ATP6V1B1 antibody - middle region (ARP56327_P050) Polyclonal Bovine, Dog, Human, Mouse, Pig, Rabbit, Rat WB 50ug $289 Details
Polyclonal Antibody ARP56326_P050 Atp6v1b1 Antibody - N-terminal region (ARP56326_P050) Mouse; Human WB 50ug $289 Details
Polyclonal Antibody OAAB07785 ATP6V1B1 antibody - center region (OAAB07785) Human WB, IHC, IF 400ul $289 Details
Polyclonal Antibody OAAB08546 ATP6V1B1 antibody - C - terminal region (OAAB08546) Human WB, IHC 400ul $289 Details
Polyclonal Antibody OAEC03181 ATP6V1B1 Antibody (OAEC03181) Human; Mouse WB, IHC, ELISA 100ug $229 Details
Polyclonal Antibody OAAF04434 ATP6V1B1 Antibody (OAAF04434) Polyclonal Human, Mouse WB, IHC, ELISA 100 ug $229 Details

Show all Atp6v1b1 antibodies


Product Images
Atp6v1b1 Antibody - N-terminal region (ARP56326_P050) in Mouse Testis cells using Western Blot

Sample Type: Mouse Testis

ATP6V1B1 antibody - middle region (ARP56327_P050) in Human HeLa cells using Western Blot

Sample Type: Human HeLa

ATP6V1B1 antibody - center region (OAAB07785) in Human Kidney cells using Immunohistochemistry

Sample Type: Human Kidney

ATP6V1B1 antibody - center region (OAAB07785) in WiDr cells using Immunofluorescence

Sample Type: WiDr

ATP6V1B1 antibody - center region (OAAB07785) in WiDr, K562 cells using Western Blot

Sample Type: WiDr, K562

ATP6V1B1 antibody - C - terminal region (OAAB08546) in 293 cells using Western Blot

Sample Type: 293

ATP6V1B1 antibody - C - terminal region (OAAB08546) in Human Breast cells using Immunohistochemistry

Sample Type: Human Breast

ATP6V1B1 Antibody (OAAF04434) in HepG2 cells using Western Blot

Sample Type: HepG2

ATP6V1B1 Antibody (OAAF04434) in Human breast carcinoma cells using Immunohistochemistry

Sample Type: Human breast carcinoma

ATP6V1B1 Antibody (OAEC03181) in HepG2 cells using Western Blot

Sample Type: HepG2

ATP6V1B1 Antibody (OAEC03181) in Human breast carcinoma cells using Immunohistochemistry

Sample Type: Human breast carcinoma


Atp6v1b1 Protocols

Publications
Related Gene Trend Categories
Species
Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas205473_at721_B_lymphoblasts6.9506.180Details
BioGPS Gene Atlas205473_atAdipocyte5.9506.180Details
BioGPS Gene Atlas205473_atAdrenalCortex6.6006.180Details
BioGPS Gene Atlas205473_atAdrenalgland5.3006.180Details
BioGPS Gene Atlas205473_atAmygdala6.2506.180Details
BioGPS Gene Atlas205473_atAppendix6.0506.180Details
BioGPS Gene Atlas205473_atAtrioventricularNode4.6006.180Details
BioGPS Gene Atlas205473_atBDCA4+_DentriticCells6.2506.180Details
BioGPS Gene Atlas205473_atBonemarrow6.3006.180Details
BioGPS Gene Atlas205473_atBronchialEpithelialCells5.9006.180Details
BioGPS Gene Atlas205473_atCD105+_Endothelial5.9006.180Details
BioGPS Gene Atlas205473_atCD14+_Monocytes6.3006.180Details
BioGPS Gene Atlas205473_atCD19+_BCells(neg._sel.)6.2506.180Details
BioGPS Gene Atlas205473_atCD33+_Myeloid7.4006.180Details
BioGPS Gene Atlas205473_atCD34+7.3506.180Details
BioGPS Gene Atlas205473_atCD4+_Tcells6.1006.180Details
BioGPS Gene Atlas205473_atCD56+_NKCells6.8006.180Details
BioGPS Gene Atlas205473_atCD71+_EarlyErythroid5.6006.180Details
BioGPS Gene Atlas205473_atCD8+_Tcells5.4006.180Details
BioGPS Gene Atlas205473_atCardiacMyocytes8.0506.180Details
BioGPS Gene Atlas205473_atCaudatenucleus5.4006.180Details
BioGPS Gene Atlas205473_atCerebellum4.9506.180Details
BioGPS Gene Atlas205473_atCerebellumPeduncles7.3006.180Details
BioGPS Gene Atlas205473_atCiliaryGanglion4.2006.180Details
BioGPS Gene Atlas205473_atCingulateCortex6.1506.180Details
BioGPS Gene Atlas205473_atColorectaladenocarcinoma6.0506.180Details
BioGPS Gene Atlas205473_atDorsalRootGanglion4.6006.180Details
BioGPS Gene Atlas205473_atFetalThyroid6.4506.180Details
BioGPS Gene Atlas205473_atFetalbrain5.8006.180Details
BioGPS Gene Atlas205473_atFetalliver5.2006.180Details
BioGPS Gene Atlas205473_atFetallung5.0006.180Details
BioGPS Gene Atlas205473_atGlobusPallidus4.4006.180Details
BioGPS Gene Atlas205473_atHeart8.5006.180Details
BioGPS Gene Atlas205473_atHypothalamus6.5006.180Details
BioGPS Gene Atlas205473_atKidney11.1006.180Details
BioGPS Gene Atlas205473_atLeukemia_chronicMyelogenousK-5625.4006.180Details
BioGPS Gene Atlas205473_atLeukemia_promyelocytic-HL-605.3006.180Details
BioGPS Gene Atlas205473_atLeukemialymphoblastic(MOLT-4)4.8006.180Details
BioGPS Gene Atlas205473_atLiver8.5006.180Details
BioGPS Gene Atlas205473_atLung6.6006.180Details
BioGPS Gene Atlas205473_atLymphnode5.1506.180Details
BioGPS Gene Atlas205473_atLymphoma_burkitts(Daudi)7.9006.180Details
BioGPS Gene Atlas205473_atLymphoma_burkitts(Raji)8.4506.180Details
BioGPS Gene Atlas205473_atMedullaOblongata5.4506.180Details
BioGPS Gene Atlas205473_atOccipitalLobe5.4006.180Details
BioGPS Gene Atlas205473_atOlfactoryBulb4.7006.180Details
BioGPS Gene Atlas205473_atOvary4.1006.180Details
BioGPS Gene Atlas205473_atPancreas5.0006.180Details
BioGPS Gene Atlas205473_atPancreaticIslet6.6006.180Details
BioGPS Gene Atlas205473_atParietalLobe6.5506.180Details
BioGPS Gene Atlas205473_atPituitary8.1506.180Details
BioGPS Gene Atlas205473_atPlacenta6.3006.180Details
BioGPS Gene Atlas205473_atPons5.7506.180Details
BioGPS Gene Atlas205473_atPrefrontalCortex7.3006.180Details
BioGPS Gene Atlas205473_atProstate7.0006.180Details
BioGPS Gene Atlas205473_atSalivarygland5.1506.180Details
BioGPS Gene Atlas205473_atSkeletalMuscle7.9006.180Details
BioGPS Gene Atlas205473_atSkin4.7506.180Details
BioGPS Gene Atlas205473_atSmoothMuscle6.8506.180Details
BioGPS Gene Atlas205473_atSpinalcord6.4006.180Details
BioGPS Gene Atlas205473_atSubthalamicNucleus5.5006.180Details
BioGPS Gene Atlas205473_atSuperiorCervicalGanglion7.3506.180Details
BioGPS Gene Atlas205473_atTemporalLobe5.5006.180Details
BioGPS Gene Atlas205473_atTestis5.3006.180Details
BioGPS Gene Atlas205473_atTestisGermCell4.9506.180Details
BioGPS Gene Atlas205473_atTestisIntersitial5.1506.180Details
BioGPS Gene Atlas205473_atTestisLeydigCell6.1006.180Details
BioGPS Gene Atlas205473_atTestisSeminiferousTubule5.2006.180Details
BioGPS Gene Atlas205473_atThalamus6.1506.180Details
BioGPS Gene Atlas205473_atThymus4.8006.180Details
BioGPS Gene Atlas205473_atThyroid7.4006.180Details
BioGPS Gene Atlas205473_atTongue6.4006.180Details
BioGPS Gene Atlas205473_atTonsil5.9006.180Details
BioGPS Gene Atlas205473_atTrachea5.0006.180Details
BioGPS Gene Atlas205473_atTrigeminalGanglion6.2006.180Details
BioGPS Gene Atlas205473_atUterus4.9006.180Details
BioGPS Gene Atlas205473_atUterusCorpus5.6006.180Details
BioGPS Gene Atlas205473_atWholeBlood6.6006.180Details
BioGPS Gene Atlas205473_atWholebrain4.9506.180Details
BioGPS Gene Atlas205473_atcolon6.0506.180Details
BioGPS Gene Atlas205473_atpineal_day7.2806.180Details
BioGPS Gene Atlas205473_atpineal_night7.1406.180Details
BioGPS Gene Atlas205473_atretina7.2006.180Details
BioGPS Gene Atlas205473_atsmall_intestine5.8006.180Details
BioGPS NCI60205473_at7864.2754.180Details
BioGPS NCI60205473_atA1724.0514.180Details
BioGPS NCI60205473_atA2044.1394.180Details
BioGPS NCI60205473_atA3614.2404.180Details
BioGPS NCI60205473_atA4984.1734.180Details
BioGPS NCI60205473_atA5494.2954.180Details
BioGPS NCI60205473_atACC34.3434.180Details
BioGPS NCI60205473_atACHN3.8024.180Details
BioGPS NCI60205473_atALVA314.4124.180Details
BioGPS NCI60205473_atCAKI14.2644.180Details
BioGPS NCI60205473_atCCRT CEM4.6354.180Details
BioGPS NCI60205473_atCOLO2054.1654.180Details
BioGPS NCI60205473_atDLD14.1174.180Details
BioGPS NCI60205473_atDU1454.0424.180Details
BioGPS NCI60205473_atEKVX4.0924.180Details
BioGPS NCI60205473_atGM1334.2394.180Details
BioGPS NCI60205473_atGM16004.2674.180Details
BioGPS NCI60205473_atGM23134.1994.180Details
BioGPS NCI60205473_atGM23454.1694.180Details
BioGPS NCI60205473_atGM24934.3144.180Details
BioGPS NCI60205473_atGM974.4674.180Details
BioGPS NCI60205473_atHCC29983.6064.180Details
BioGPS NCI60205473_atHCT1164.1894.180Details
BioGPS NCI60205473_atHCT153.8764.180Details
BioGPS NCI60205473_atHEK 293 T-rex4.4284.180Details
BioGPS NCI60205473_atHEK 293T4.2264.180Details
BioGPS NCI60205473_atHEK2934.1064.180Details
BioGPS NCI60205473_atHELA3.8884.180Details
BioGPS NCI60205473_atHEPG24.1594.180Details
BioGPS NCI60205473_atHL604.5784.180Details
BioGPS NCI60205473_atHOP624.1794.180Details
BioGPS NCI60205473_atHOP923.9604.180Details
BioGPS NCI60205473_atHS578T4.0864.180Details
BioGPS NCI60205473_atHSG4.0754.180Details
BioGPS NCI60205473_atHT10804.0704.180Details
BioGPS NCI60205473_atHT294.9434.180Details
BioGPS NCI60205473_atIGROV14.0764.180Details
BioGPS NCI60205473_atIOSE804.1254.180Details
BioGPS NCI60205473_atJURKAT4.1504.180Details
BioGPS NCI60205473_atK5624.3324.180Details
BioGPS NCI60205473_atKM124.2464.180Details
BioGPS NCI60205473_atLN183.8884.180Details
BioGPS NCI60205473_atLNCAP4.1504.180Details
BioGPS NCI60205473_atLOX IMVI4.1474.180Details
BioGPS NCI60205473_atM144.1324.180Details
BioGPS NCI60205473_atMALME 3M4.4084.180Details
BioGPS NCI60205473_atMCF73.9964.180Details
BioGPS NCI60205473_atMD MB2314.1864.180Details
BioGPS NCI60205473_atMDA MB4354.6304.180Details
BioGPS NCI60205473_atMOLT44.2894.180Details
BioGPS NCI60205473_atNCI 4604.2474.180Details
BioGPS NCI60205473_atNCI H2264.2374.180Details
BioGPS NCI60205473_atNCI H234.2104.180Details
BioGPS NCI60205473_atNCI H322M4.1794.180Details
BioGPS NCI60205473_atNCVADR RES4.0304.180Details
BioGPS NCI60205473_atOVCAR34.3524.180Details
BioGPS NCI60205473_atOVCAR44.1374.180Details
BioGPS NCI60205473_atOVCAR54.1234.180Details
BioGPS NCI60205473_atOVCAR83.8784.180Details
BioGPS NCI60205473_atPANC14.2464.180Details
BioGPS NCI60205473_atRL74.2094.180Details
BioGPS NCI60205473_atRPMI 82264.3794.180Details
BioGPS NCI60205473_atRS118464.2894.180Details
BioGPS NCI60205473_atRXF3934.1524.180Details
BioGPS NCI60205473_atSAOS24.2174.180Details
BioGPS NCI60205473_atSF2684.1474.180Details
BioGPS NCI60205473_atSF2954.0954.180Details
BioGPS NCI60205473_atSF5393.7614.180Details
BioGPS NCI60205473_atSHSYSY+RA3.8964.180Details
BioGPS NCI60205473_atSHSYSY-RA4.1404.180Details
BioGPS NCI60205473_atSKMEL24.1624.180Details
BioGPS NCI60205473_atSKMEL284.1544.180Details
BioGPS NCI60205473_atSKMEL54.0854.180Details
BioGPS NCI60205473_atSKOV34.3054.180Details
BioGPS NCI60205473_atSN12C4.1704.180Details
BioGPS NCI60205473_atSNB194.0364.180Details
BioGPS NCI60205473_atSNB754.1064.180Details
BioGPS NCI60205473_atSR4.2174.180Details
BioGPS NCI60205473_atSW6204.2694.180Details
BioGPS NCI60205473_atT244.2544.180Details
BioGPS NCI60205473_atT3M44.2454.180Details
BioGPS NCI60205473_atTK104.1314.180Details
BioGPS NCI60205473_atU1184.1174.180Details
BioGPS NCI60205473_atU1384.0404.180Details
BioGPS NCI60205473_atU20S4.1044.180Details
BioGPS NCI60205473_atU2514.0634.180Details
BioGPS NCI60205473_atU874.0794.180Details
BioGPS NCI60205473_atUACC2574.1214.180Details
BioGPS NCI60205473_atUACC624.2354.180Details
BioGPS NCI60205473_atUO313.9634.180Details
BioGPS NCI60205473_atZR75_14.2414.180Details
BioGPS NCI60205473_atastrocytes4.2484.180Details
BioGPS NCI60205473_athuh-74.4044.180Details