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Gene ID: 50617 | ATP6V0A4 Antibody Resource


ATP6V0A4 Antibody Resource
Gene Full Name: 
ATPase, H+ transporting, lysosomal V0 subunit a4
Uniprot: 
Q9HBG4
Protein Name: 
V-type proton ATPase 116 kDa subunit a isoform 4
Nucleotide: 
XM_005250393
Alias: 
A4;STV1;VPH1;VPP2;RTA1C;RTADR;ATP6N2;RDRTA2;ATP6N1B;
Ensembl: 
ENSG00000105929
Location: 
7q34
HPRD: 
05576
NCBI Gene: 
50617
MIM: 
605239

Summary: 
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing. [provided by RefSeq, Jul 2008]
Function: 
Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney .
Subcellular location: 
Apical cell membrane; Multi-pass membrane protein. Note: Present at high density almost exclusively on the apical surface of alpha-intercalated cells in the cortical collecting ducts of the distal nephron.
PTM: 
Disease: 
Renal tubular acidosis, distal, autosomal recessive (RTADR) [MIM:602722]: An autosomal recessive disease characterized by reduced ability to acidify urine, variable hyperchloremic hypokalemic metabolic acidosis, nephrocalcinosis, and nephrolithiasis. It is due to functional failure of alpha-intercalated cells of the cortical collecting duct of the distal nephron, where vectorial proton transport is required for urinary acidification. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB02785 ATP6V0A4 antibody - center region (OAAB02785) Human WB, ELISA 400ul $289 Details
Polyclonal Antibody ARP49528_P050 ATP6V0A4 Antibody (ARP49528_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP49529_P050 ATP6V0A4 Antibody (ARP49529_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAGA00893 ATP6V0A4 antibody (OAGA00893) Polyclonal Human WB 100 ul $340 Details

Show all ATP6V0A4 antibodies


Product Images
ATP6V0A4 antibody - center region (OAAB02785) in CEM cells using Western Blot

Sample Type: CEM


ATP6V0A4 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP49529 African clawed frog ATP6V0A4 antibody; Xenopus laevis ATP6V0A4 antibody Q6PA83 86.0%
ARP46582 African clawed frog ATP6V0A4 antibody; Xenopus laevis ATP6V0A4 antibody Q6PA83 79.0%
ARP49529 Bovine ATP6V0A4 antibody; Bos taurus ATP6V0A4 antibody E1BGJ7 93.0%
ARP49529 Cat ATP6V0A4 antibody; Felis catus ATP6V0A4 antibody M3WGV8 100.0%
ARP49529 Chimpanzee ATP6V0A4 antibody; Pan troglodytes ATP6V0A4 antibody H2QVG4 100.0%
ARP49529 Chinese softshell turtle ATP6V0A4 antibody; Pelodiscus sinensis ATP6V0A4 antibody K7GAR5 93.0%
ARP49529 Chinese softshell turtle ATP6V0A4 antibody; Pelodiscus sinensis ATP6V0A4 antibody K7GAS1 93.0%
ARP49529 Collared flycatcher ATP6V0A4 antibody; Ficedula albicollis ATP6V0A4 antibody U3K337 93.0%
ARP49529 Common turkey ATP6V0A4 antibody; Meleagris gallopavo ATP6V0A4 antibody G1NKD3 93.0%
ARP49529 Dog ATP6V0A4 antibody; Canis familiaris ATP6V0A4 antibody E2RR34 100.0%
ARP49529 Domestic duck ATP6V0A4 antibody; Anas platyrhynchos ATP6V0A4 antibody U3IB07 93.0%
ARP49529 Duckbill platypus ATP6V0A4 antibody; Ornithorhynchus anatinus ATP6V0A4 antibody F7G470 93.0%
ARP49529 Duckbill platypus ATP6V0A4 antibody; Ornithorhynchus anatinus ATP6V0A4 antibody F7G475 93.0%
ARP49529 European domestic ferret ATP6V0A4 antibody; Mustela putorius furo ATP6V0A4 antibody M3XXL4 100.0%
ARP49529 Giant panda ATP6V0A4 antibody; Ailuropoda melanoleuca ATP6V0A4 antibody D2GYN5 93.0%
ARP49529 Giant panda ATP6V0A4 antibody; Ailuropoda melanoleuca ATP6V0A4 antibody G1MI19 93.0%
ARP49529 Gray short-tailed opossum ATP6V0A4 antibody; Monodelphis domestica ATP6V0A4 antibody F6SXF7 100.0%
ARP49529 Green anole ATP6V0A4 antibody; Anolis carolinensis ATP6V0A4 antibody G1KP65 85.0%
ARP49529 Horse ATP6V0A4 antibody; Equus caballus ATP6V0A4 antibody F6QEP7 100.0%
ARP49529 Horse ATP6V0A4 antibody; Equus caballus ATP6V0A4 antibody F6QF85 100.0%
ARP49529 Horse ATP6V0A4 antibody; Equus caballus ATP6V0A4 antibody F6QG54 100.0%
ARP49529 Horse ATP6V0A4 antibody; Equus caballus ATP6V0A4 antibody F6QMW3 100.0%
ARP49529 Horse ATP6V0A4 antibody; Equus caballus ATP6V0A4 antibody F6QNX8 100.0%
ARP49529 Human ATP6V0A4 antibody; Homo sapiens ATP6V0A4 antibody Q9HBG4 100.0%
ARP49529 Mouse ATP6V0A4 antibody; Mus musculus ATP6V0A4 antibody Q6ZQM9 100.0%
ARP49529 Mouse ATP6V0A4 antibody; Mus musculus ATP6V0A4 antibody Q920R6 100.0%
ARP49529 Northern white-cheeked gibbon ATP6V0A4 antibody; Nomascus leucogenys ATP6V0A4 antibody G1RUK1 100.0%
ARP49529 Pig ATP6V0A4 antibody; Sus scrofa ATP6V0A4 antibody F1SNJ8 100.0%
ARP49529 Rabbit ATP6V0A4 antibody; Oryctolagus cuniculus ATP6V0A4 antibody G1T5M6 100.0%
ARP49529 Rat ATP6V0A4 antibody; Rattus norvegicus ATP6V0A4 antibody D4A1H0 100.0%
ARP49529 Rhesus macaque ATP6V0A4 antibody; Macaca mulatta ATP6V0A4 antibody F7HS25 100.0%
ARP49529 Rhesus macaque ATP6V0A4 antibody; Macaca mulatta ATP6V0A4 antibody F7HS26 100.0%
ARP49529 Small-eared galago ATP6V0A4 antibody; Otolemur garnettii ATP6V0A4 antibody H0XGX3 93.0%
ARP49529 Sumatran orangutan ATP6V0A4 antibody; Pongo abelii ATP6V0A4 antibody H2PNM8 93.0%
ARP49529 Tasmanian devil ATP6V0A4 antibody; Sarcophilus harrisii ATP6V0A4 antibody G3VGX5 100.0%
ARP49529 Tasmanian devil ATP6V0A4 antibody; Sarcophilus harrisii ATP6V0A4 antibody G3VGX6 100.0%
ARP49529 Tasmanian devil ATP6V0A4 antibody; Sarcophilus harrisii ATP6V0A4 antibody G3VGX7 100.0%
ARP49529 Thirteen-lined ground squirrel ATP6V0A4 antibody; Spermophilus tridecemlineatus ATP6V0A4 antibody I3LZ88 100.0%
ARP49529 Western clawed frog ATP6V0A4 antibody; Xenopus tropicalis ATP6V0A4 antibody A9UMJ2 86.0%
ARP46582 Western clawed frog ATP6V0A4 antibody; Xenopus tropicalis ATP6V0A4 antibody A9UMJ2 79.0%
ARP49529 Zebra finch ATP6V0A4 antibody; Taeniopygia guttata ATP6V0A4 antibody H0ZMF1 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas220197_at721_B_lymphoblasts5.0004.280Details
BioGPS Gene Atlas220197_atAdipocyte3.9504.280Details
BioGPS Gene Atlas220197_atAdrenalCortex4.4004.280Details
BioGPS Gene Atlas220197_atAdrenalgland3.4504.280Details
BioGPS Gene Atlas220197_atAmygdala4.2004.280Details
BioGPS Gene Atlas220197_atAppendix4.1004.280Details
BioGPS Gene Atlas220197_atAtrioventricularNode3.2504.280Details
BioGPS Gene Atlas220197_atBDCA4+_DentriticCells4.3504.280Details
BioGPS Gene Atlas220197_atBonemarrow4.1504.280Details
BioGPS Gene Atlas220197_atBronchialEpithelialCells3.9504.280Details
BioGPS Gene Atlas220197_atCD105+_Endothelial4.0504.280Details
BioGPS Gene Atlas220197_atCD14+_Monocytes4.3004.280Details
BioGPS Gene Atlas220197_atCD19+_BCells(neg._sel.)4.2004.280Details
BioGPS Gene Atlas220197_atCD33+_Myeloid5.1004.280Details
BioGPS Gene Atlas220197_atCD34+5.0504.280Details
BioGPS Gene Atlas220197_atCD4+_Tcells4.3504.280Details
BioGPS Gene Atlas220197_atCD56+_NKCells4.7504.280Details
BioGPS Gene Atlas220197_atCD71+_EarlyErythroid3.8004.280Details
BioGPS Gene Atlas220197_atCD8+_Tcells3.8004.280Details
BioGPS Gene Atlas220197_atCardiacMyocytes5.3004.280Details
BioGPS Gene Atlas220197_atCaudatenucleus3.6004.280Details
BioGPS Gene Atlas220197_atCerebellum3.3004.280Details
BioGPS Gene Atlas220197_atCerebellumPeduncles4.6004.280Details
BioGPS Gene Atlas220197_atCiliaryGanglion3.0004.280Details
BioGPS Gene Atlas220197_atCingulateCortex4.2004.280Details
BioGPS Gene Atlas220197_atColorectaladenocarcinoma4.0504.280Details
BioGPS Gene Atlas220197_atDorsalRootGanglion3.2004.280Details
BioGPS Gene Atlas220197_atFetalThyroid3.9004.280Details
BioGPS Gene Atlas220197_atFetalbrain4.0004.280Details
BioGPS Gene Atlas220197_atFetalliver3.5004.280Details
BioGPS Gene Atlas220197_atFetallung3.3004.280Details
BioGPS Gene Atlas220197_atGlobusPallidus3.0504.280Details
BioGPS Gene Atlas220197_atHeart5.2004.280Details
BioGPS Gene Atlas220197_atHypothalamus4.3504.280Details
BioGPS Gene Atlas220197_atKidney14.4504.280Details
BioGPS Gene Atlas220197_atLeukemia_chronicMyelogenousK-5623.6504.280Details
BioGPS Gene Atlas220197_atLeukemia_promyelocytic-HL-603.5504.280Details
BioGPS Gene Atlas220197_atLeukemialymphoblastic(MOLT-4)3.2504.280Details
BioGPS Gene Atlas220197_atLiver5.4004.280Details
BioGPS Gene Atlas220197_atLung4.4004.280Details
BioGPS Gene Atlas220197_atLymphnode3.4004.280Details
BioGPS Gene Atlas220197_atLymphoma_burkitts(Daudi)5.1504.280Details
BioGPS Gene Atlas220197_atLymphoma_burkitts(Raji)5.7004.280Details
BioGPS Gene Atlas220197_atMedullaOblongata3.6504.280Details
BioGPS Gene Atlas220197_atOccipitalLobe3.6004.280Details
BioGPS Gene Atlas220197_atOlfactoryBulb3.2004.280Details
BioGPS Gene Atlas220197_atOvary2.7004.280Details
BioGPS Gene Atlas220197_atPancreas3.3004.280Details
BioGPS Gene Atlas220197_atPancreaticIslet4.3504.280Details
BioGPS Gene Atlas220197_atParietalLobe4.4004.280Details
BioGPS Gene Atlas220197_atPituitary4.6504.280Details
BioGPS Gene Atlas220197_atPlacenta4.1004.280Details
BioGPS Gene Atlas220197_atPons3.8504.280Details
BioGPS Gene Atlas220197_atPrefrontalCortex4.9504.280Details
BioGPS Gene Atlas220197_atProstate4.6504.280Details
BioGPS Gene Atlas220197_atSalivarygland9.4504.280Details
BioGPS Gene Atlas220197_atSkeletalMuscle4.9504.280Details
BioGPS Gene Atlas220197_atSkin3.4504.280Details
BioGPS Gene Atlas220197_atSmoothMuscle4.5504.280Details
BioGPS Gene Atlas220197_atSpinalcord4.3004.280Details
BioGPS Gene Atlas220197_atSubthalamicNucleus3.7504.280Details
BioGPS Gene Atlas220197_atSuperiorCervicalGanglion4.7004.280Details
BioGPS Gene Atlas220197_atTemporalLobe3.7004.280Details
BioGPS Gene Atlas220197_atTestis3.4004.280Details
BioGPS Gene Atlas220197_atTestisGermCell3.3004.280Details
BioGPS Gene Atlas220197_atTestisIntersitial3.4004.280Details
BioGPS Gene Atlas220197_atTestisLeydigCell4.0004.280Details
BioGPS Gene Atlas220197_atTestisSeminiferousTubule3.4504.280Details
BioGPS Gene Atlas220197_atThalamus4.1004.280Details
BioGPS Gene Atlas220197_atThymus3.1504.280Details
BioGPS Gene Atlas220197_atThyroid5.0004.280Details
BioGPS Gene Atlas220197_atTongue4.0504.280Details
BioGPS Gene Atlas220197_atTonsil3.9004.280Details
BioGPS Gene Atlas220197_atTrachea3.6504.280Details
BioGPS Gene Atlas220197_atTrigeminalGanglion4.1004.280Details
BioGPS Gene Atlas220197_atUterus3.2504.280Details
BioGPS Gene Atlas220197_atUterusCorpus3.6504.280Details
BioGPS Gene Atlas220197_atWholeBlood4.3504.280Details
BioGPS Gene Atlas220197_atWholebrain3.3504.280Details
BioGPS Gene Atlas220197_atcolon4.0504.280Details
BioGPS Gene Atlas220197_atpineal_day5.0204.280Details
BioGPS Gene Atlas220197_atpineal_night4.9004.280Details
BioGPS Gene Atlas220197_atretina4.8504.280Details
BioGPS Gene Atlas220197_atsmall_intestine3.8504.280Details
BioGPS NCI60220197_at7864.23319.660Details
BioGPS NCI60220197_atA1723.92219.660Details
BioGPS NCI60220197_atA2044.07919.660Details
BioGPS NCI60220197_atA3614.17019.660Details
BioGPS NCI60220197_atA4984.11219.660Details
BioGPS NCI60220197_atA5494.19419.660Details
BioGPS NCI60220197_atACC34.32519.660Details
BioGPS NCI60220197_atACHN3.87519.660Details
BioGPS NCI60220197_atALVA314.39319.660Details
BioGPS NCI60220197_atCAKI14.29119.660Details
BioGPS NCI60220197_atCCRT CEM4.92419.660Details
BioGPS NCI60220197_atCOLO2054.16019.660Details
BioGPS NCI60220197_atDLD14.04019.660Details
BioGPS NCI60220197_atDU1453.96119.660Details
BioGPS NCI60220197_atEKVX3.95919.660Details
BioGPS NCI60220197_atGM1334.22219.660Details
BioGPS NCI60220197_atGM16004.30119.660Details
BioGPS NCI60220197_atGM23134.17619.660Details
BioGPS NCI60220197_atGM23454.13419.660Details
BioGPS NCI60220197_atGM24934.32119.660Details
BioGPS NCI60220197_atGM974.61219.660Details
BioGPS NCI60220197_atHCC29983.75219.660Details
BioGPS NCI60220197_atHCT1164.11019.660Details
BioGPS NCI60220197_atHCT153.91519.660Details
BioGPS NCI60220197_atHEK 293 T-rex4.19219.660Details
BioGPS NCI60220197_atHEK 293T4.10619.660Details
BioGPS NCI60220197_atHEK2934.09419.660Details
BioGPS NCI60220197_atHELA4.00419.660Details
BioGPS NCI60220197_atHEPG24.10319.660Details
BioGPS NCI60220197_atHL604.30919.660Details
BioGPS NCI60220197_atHOP624.12119.660Details
BioGPS NCI60220197_atHOP924.00319.660Details
BioGPS NCI60220197_atHS578T4.05319.660Details
BioGPS NCI60220197_atHSG3.97919.660Details
BioGPS NCI60220197_atHT10804.08319.660Details
BioGPS NCI60220197_atHT294.42919.660Details
BioGPS NCI60220197_atIGROV14.07019.660Details
BioGPS NCI60220197_atIOSE804.09119.660Details
BioGPS NCI60220197_atJURKAT4.10919.660Details
BioGPS NCI60220197_atK5624.40719.660Details
BioGPS NCI60220197_atKM124.28619.660Details
BioGPS NCI60220197_atLN183.87619.660Details
BioGPS NCI60220197_atLNCAP4.11919.660Details
BioGPS NCI60220197_atLOX IMVI4.11019.660Details
BioGPS NCI60220197_atM144.06819.660Details
BioGPS NCI60220197_atMALME 3M4.36919.660Details
BioGPS NCI60220197_atMCF73.98719.660Details
BioGPS NCI60220197_atMD MB2314.19819.660Details
BioGPS NCI60220197_atMDA MB4354.42119.660Details
BioGPS NCI60220197_atMOLT44.29019.660Details
BioGPS NCI60220197_atNCI 4604.23119.660Details
BioGPS NCI60220197_atNCI H2264.20719.660Details
BioGPS NCI60220197_atNCI H234.11219.660Details
BioGPS NCI60220197_atNCI H322M4.11119.660Details
BioGPS NCI60220197_atNCVADR RES4.05519.660Details
BioGPS NCI60220197_atOVCAR34.30219.660Details
BioGPS NCI60220197_atOVCAR44.09819.660Details
BioGPS NCI60220197_atOVCAR54.04519.660Details
BioGPS NCI60220197_atOVCAR84.17919.660Details
BioGPS NCI60220197_atPANC14.18919.660Details
BioGPS NCI60220197_atRL74.18219.660Details
BioGPS NCI60220197_atRPMI 82264.16719.660Details
BioGPS NCI60220197_atRS118464.31319.660Details
BioGPS NCI60220197_atRXF3934.08819.660Details
BioGPS NCI60220197_atSAOS24.16319.660Details
BioGPS NCI60220197_atSF2684.11519.660Details
BioGPS NCI60220197_atSF2954.04119.660Details
BioGPS NCI60220197_atSF5393.89319.660Details
BioGPS NCI60220197_atSHSYSY+RA3.99919.660Details
BioGPS NCI60220197_atSHSYSY-RA4.07119.660Details
BioGPS NCI60220197_atSKMEL229.21719.660Details
BioGPS NCI60220197_atSKMEL284.12119.660Details
BioGPS NCI60220197_atSKMEL51656.13019.660Details
BioGPS NCI60220197_atSKOV34.26619.660Details
BioGPS NCI60220197_atSN12C4.07519.660Details
BioGPS NCI60220197_atSNB193.92519.660Details
BioGPS NCI60220197_atSNB754.09019.660Details
BioGPS NCI60220197_atSR4.48119.660Details
BioGPS NCI60220197_atSW6204.17219.660Details
BioGPS NCI60220197_atT244.22419.660Details
BioGPS NCI60220197_atT3M44.30719.660Details
BioGPS NCI60220197_atTK104.09719.660Details
BioGPS NCI60220197_atU1184.01819.660Details
BioGPS NCI60220197_atU1383.88219.660Details
BioGPS NCI60220197_atU20S4.03619.660Details
BioGPS NCI60220197_atU2514.05019.660Details
BioGPS NCI60220197_atU874.00019.660Details
BioGPS NCI60220197_atUACC2574.08419.660Details
BioGPS NCI60220197_atUACC624.20619.660Details
BioGPS NCI60220197_atUO313.98619.660Details
BioGPS NCI60220197_atZR75_14.21819.660Details
BioGPS NCI60220197_atastrocytes4.12719.660Details
BioGPS NCI60220197_athuh-74.23519.660Details