Gene ID: 51062 | ATL1 Antibody Resource
ATL1 Antibody Resource
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Tissue & Cell Line Gene Expression Data
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Summary: | The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Function: | GTPase tethering membranes through formation of trans-homooligomer and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development. |
Subcellular location: | Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection › axon . |
PTM: | Phosphoprotein; |
Disease: | Spastic paraplegia 3, autosomal dominant (SPG3) [MIM:182600]: A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. Note: The disease is caused by mutations affecting the gene represented in this entry. Hereditary sensory neuropathy 1D (HSN1D) [MIM:613708]: A disease characterized by adult-onset distal axonal sensory neuropathy leading to mutilating ulcerations as well as hyporeflexia. Some patients may show features suggesting upper neuron involvement. Note: The disease is caused by mutations affecting the gene represented in this entry. |
Biotechnological use: |
Antibodies
| Type | Catalog | Name | Clonality | Species Reactivity | Application | Size | Price | More Info |
|---|---|---|---|---|---|---|---|---|
| Polyclonal Antibody | OAAB12214 | ATL1 antibody - C - terminal region (OAAB12214) | Human | WB | 400ul | $289 | Details |
Product Images
 Sample Type: NCI-H292 |
ATL1 Protocols
- • Product Protocol: ATL1 antibody tested with human NCI-H292 by western blot (OAAB12214) Review
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Publications
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Related Gene Trend Categories
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Species
| Catalog | Predicted Species & Target | Target Reference | Predicted Homology |
|---|---|---|---|
| ARP64901 | African elephant ATL1 antibody; Loxodonta africana ATL1 antibody | G3TC17 | 100.0% |
| ARP64901 | African elephant ATL1 antibody; Loxodonta africana ATL1 antibody | G3TXP2 | 100.0% |
| ARP64900 | African elephant ATL1 antibody; Loxodonta africana ATL1 antibody | G3TC17 | 92.0% |
| ARP64900 | African elephant ATL1 antibody; Loxodonta africana ATL1 antibody | G3TXP2 | 92.0% |
| ARP64900 | Bovine ATL1 antibody; Bos taurus ATL1 antibody | Q58D72 | 100.0% |
| ARP64901 | Bovine ATL1 antibody; Bos taurus ATL1 antibody | Q58D72 | 100.0% |
| ARP64900 | Cat ATL1 antibody; Felis catus ATL1 antibody | M3WXA3 | 100.0% |
| ARP64901 | Cat ATL1 antibody; Felis catus ATL1 antibody | M3WXA3 | 100.0% |
| ARP64901 | Chicken ATL1 antibody; Gallus gallus ATL1 antibody | F1NAM6 | 100.0% |
| ARP64901 | Chimpanzee ATL1 antibody; Pan troglodytes ATL1 antibody | H2QZF3 | 100.0% |
| ARP64901 | Chimpanzee ATL1 antibody; Pan troglodytes ATL1 antibody | H2R0R0 | 100.0% |
| ARP64901 | Chimpanzee ATL1 antibody; Pan troglodytes ATL1 antibody | H2R3T9 | 100.0% |
| ARP64900 | Chimpanzee ATL1 antibody; Pan troglodytes ATL1 antibody | H2QZF3 | 93.0% |
| ARP64900 | Chimpanzee ATL1 antibody; Pan troglodytes ATL1 antibody | H2R0R0 | 93.0% |
| ARP64900 | Chimpanzee ATL1 antibody; Pan troglodytes ATL1 antibody | H2R3T9 | 93.0% |
| ARP64901 | Chinese softshell turtle ATL1 antibody; Pelodiscus sinensis ATL1 antibody | K7FBX0 | 100.0% |
| ARP64901 | Collared flycatcher ATL1 antibody; Ficedula albicollis ATL1 antibody | U3JGM6 | 100.0% |
| ARP64900 | Crab-eating macaque ATL1 antibody; Macaca fascicularis ATL1 antibody | Q60HD2 | 100.0% |
| ARP64901 | Crab-eating macaque ATL1 antibody; Macaca fascicularis ATL1 antibody | Q60HD2 | 100.0% |
| ARP64900 | Dog ATL1 antibody; Canis familiaris ATL1 antibody | F1Q4H4 | 100.0% |
| ARP64901 | Dog ATL1 antibody; Canis familiaris ATL1 antibody | F1Q4H4 | 100.0% |
| ARP64900 | Dog ATL1 antibody; Canis familiaris ATL1 antibody | F6X7C0 | 100.0% |
| ARP64901 | Dog ATL1 antibody; Canis familiaris ATL1 antibody | F6X7C0 | 100.0% |
| ARP64901 | Domestic duck ATL1 antibody; Anas platyrhynchos ATL1 antibody | U3I6I6 | 100.0% |
| ARP64901 | Duckbill platypus ATL1 antibody; Ornithorhynchus anatinus ATL1 antibody | F6VNS3 | 100.0% |
| ARP64900 | Duckbill platypus ATL1 antibody; Ornithorhynchus anatinus ATL1 antibody | F6VNS3 | 92.0% |
| ARP64900 | European domestic ferret ATL1 antibody; Mustela putorius furo ATL1 antibody | M3Y168 | 100.0% |
| ARP64901 | European domestic ferret ATL1 antibody; Mustela putorius furo ATL1 antibody | M3Y168 | 100.0% |
| ARP64900 | Giant panda ATL1 antibody; Ailuropoda melanoleuca ATL1 antibody | G1LTT3 | 100.0% |
| ARP64901 | Giant panda ATL1 antibody; Ailuropoda melanoleuca ATL1 antibody | G1LTT3 | 100.0% |
| ARP64900 | Giant panda ATL1 antibody; Ailuropoda melanoleuca ATL1 antibody | G1LTT9 | 100.0% |
| ARP64901 | Giant panda ATL1 antibody; Ailuropoda melanoleuca ATL1 antibody | G1LTT9 | 100.0% |
| ARP64901 | Gray short-tailed opossum ATL1 antibody; Monodelphis domestica ATL1 antibody | F7EX94 | 100.0% |
| ARP64900 | Horse ATL1 antibody; Equus caballus ATL1 antibody | F6RNF6 | 100.0% |
| ARP64901 | Horse ATL1 antibody; Equus caballus ATL1 antibody | F6RNF6 | 100.0% |
| ARP64901 | Human ATL1 antibody; Homo sapiens ATL1 antibody | G3V334 | 100.0% |
| ARP64900 | Human ATL1 antibody; Homo sapiens ATL1 antibody | F8WD04 | 100.0% |
| ARP33293 | Human ATL1 antibody; Homo sapiens ATL1 antibody | L8B8F6 | 100.0% |
| ARP64901 | Human ATL1 antibody; Homo sapiens ATL1 antibody | F8WD04 | 100.0% |
| ARP64900 | Human ATL1 antibody; Homo sapiens ATL1 antibody | Q8WXF7-2 | 100.0% |
| ARP33294 | Human ATL1 antibody; Homo sapiens ATL1 antibody | L8B8F6 | 100.0% |
| ARP64901 | Human ATL1 antibody; Homo sapiens ATL1 antibody | Q8WXF7-2 | 100.0% |
| ARP39569 | Human ATL1 antibody; Homo sapiens ATL1 antibody | L8B8F6 | 100.0% |
| ARP64900 | Human ATL1 antibody; Homo sapiens ATL1 antibody | Q8WXF7 | 100.0% |
| ARP39819 | Human ATL1 antibody; Homo sapiens ATL1 antibody | L8B8F6 | 100.0% |
| ARP64901 | Human ATL1 antibody; Homo sapiens ATL1 antibody | Q8WXF7 | 100.0% |
| ARP39820 | Human ATL1 antibody; Homo sapiens ATL1 antibody | L8B8F6 | 100.0% |
| ARP30893 | Human ATL1 antibody; Homo sapiens ATL1 antibody | L8B8F6 | 92.0% |
| ARP33041 | Human ATL1 antibody; Homo sapiens ATL1 antibody | L8B8F6 | 86.0% |
| ARP33040 | Human ATL1 antibody; Homo sapiens ATL1 antibody | L8B8F6 | 83.0% |
| ARP64901 | Mouse ATL1 antibody; Mus musculus ATL1 antibody | Q8BH66 | 100.0% |
| ARP64900 | Northern white-cheeked gibbon ATL1 antibody; Nomascus leucogenys ATL1 antibody | G1RNM0 | 100.0% |
| ARP64901 | Northern white-cheeked gibbon ATL1 antibody; Nomascus leucogenys ATL1 antibody | G1RNM0 | 100.0% |
| ARP64900 | Pig ATL1 antibody; Sus scrofa ATL1 antibody | F1SHX5 | 100.0% |
| ARP64901 | Pig ATL1 antibody; Sus scrofa ATL1 antibody | F1SHX5 | 100.0% |
| ARP64901 | Rabbit ATL1 antibody; Oryctolagus cuniculus ATL1 antibody | G1TE90 | 100.0% |
| ARP64900 | Rabbit ATL1 antibody; Oryctolagus cuniculus ATL1 antibody | G1TE90 | 92.0% |
| ARP64901 | Rat ATL1 antibody; Rattus norvegicus ATL1 antibody | Q6PST4 | 100.0% |
| ARP64900 | Rat ATL1 antibody; Rattus norvegicus ATL1 antibody | Q6PST4 | 85.0% |
| ARP64901 | Rhesus macaque ATL1 antibody; Macaca mulatta ATL1 antibody | F6X4P5 | 100.0% |
| ARP64900 | Rhesus macaque ATL1 antibody; Macaca mulatta ATL1 antibody | F6X4Q4 | 100.0% |
| ARP64901 | Rhesus macaque ATL1 antibody; Macaca mulatta ATL1 antibody | F6X4Q4 | 100.0% |
| ARP64900 | Rhesus macaque ATL1 antibody; Macaca mulatta ATL1 antibody | H9FV60 | 100.0% |
| ARP64901 | Rhesus macaque ATL1 antibody; Macaca mulatta ATL1 antibody | H9FV60 | 100.0% |
| ARP64900 | Rhesus macaque ATL1 antibody; Macaca mulatta ATL1 antibody | H9FV61 | 100.0% |
| ARP64901 | Rhesus macaque ATL1 antibody; Macaca mulatta ATL1 antibody | H9FV61 | 100.0% |
| ARP64901 | Small-eared galago ATL1 antibody; Otolemur garnettii ATL1 antibody | H0XAY0 | 100.0% |
| ARP64900 | Small-eared galago ATL1 antibody; Otolemur garnettii ATL1 antibody | H0XAY0 | 93.0% |
| ARP64901 | Spotted green pufferfish ATL1 antibody; Tetraodon nigroviridis ATL1 antibody | H3DPT7 | 100.0% |
| ARP64900 | Sumatran orangutan ATL1 antibody; Pongo abelii ATL1 antibody | Q5R4P1 | 100.0% |
| ARP64901 | Sumatran orangutan ATL1 antibody; Pongo abelii ATL1 antibody | Q5R4P1 | 100.0% |
| ARP64901 | Tasmanian devil ATL1 antibody; Sarcophilus harrisii ATL1 antibody | G3VML7 | 100.0% |
| ARP64900 | Thirteen-lined ground squirrel ATL1 antibody; Spermophilus tridecemlineatus ATL1 antibody | I3MI80 | 100.0% |
| ARP64901 | Western clawed frog ATL1 antibody; Xenopus tropicalis ATL1 antibody | Q0VFK0 | 100.0% |
| ARP64901 | Western clawed frog ATL1 antibody; Xenopus tropicalis ATL1 antibody | F7DVU9 | 100.0% |
| ARP64901 | Western clawed frog ATL1 antibody; Xenopus tropicalis ATL1 antibody | F7DVW8 | 100.0% |
| ARP64900 | White-tufted-ear marmoset ATL1 antibody; Callithrix jacchus ATL1 antibody | F7E6J5 | 100.0% |
| ARP64901 | White-tufted-ear marmoset ATL1 antibody; Callithrix jacchus ATL1 antibody | F7E6J5 | 100.0% |
| ARP64900 | White-tufted-ear marmoset ATL1 antibody; Callithrix jacchus ATL1 antibody | F7EJ48 | 100.0% |
| ARP64901 | White-tufted-ear marmoset ATL1 antibody; Callithrix jacchus ATL1 antibody | F7EJ48 | 100.0% |
| ARP64901 | Zebra finch ATL1 antibody; Taeniopygia guttata ATL1 antibody | H0ZSG3 | 100.0% |
| ARP64901 | Zebrafish ATL1 antibody; Danio rerio ATL1 antibody | B8A6H1 | 100.0% |
| ARP64901 | Zebrafish ATL1 antibody; Danio rerio ATL1 antibody | E9QGX9 | 100.0% |
| ARP64901 | Zebrafish ATL1 antibody; Danio rerio ATL1 antibody | F1R155 | 100.0% |
Tissue & Cell Line Gene Expression Data