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Gene ID: 84938 | ATG4C Antibody Resource


ATG4C Antibody Resource
Gene Full Name: 
autophagy related 4C, cysteine peptidase
Uniprot: 
Q96DT6
Protein Name: 
cysteine protease ATG4C
Nucleotide: 
NM_032852
Alias: 
APG4C;AUTL1;AUTL3;APG4-C;
Ensembl: 
ENSG00000125703
Location: 
1p31.3
HPRD: 
07473
NCBI Gene: 
84938
MIM: 
611339

Summary: 
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008]
Function: 
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation . Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Subcellular location: 
Cytoplasm.
PTM: 
Acetylation;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP58863_P050 ATG4C antibody - middle region (ARP58863_P050) Polyclonal Bovine, Dog, Horse, Human WB 50ug $289 Details
Polyclonal Antibody OAAB01772 ATG4C Antibody (OAAB01772) Human DB, ELISA 400ul $289 Details
Polyclonal Antibody OAAB01779 ATG4C Antibody (OAAB01779) Human DB, ELISA 400ul $289 Details
Polyclonal Antibody OAAB01826 ATG4C Antibody (OAAB01826) Human DB, ELISA 400ul $289 Details
Polyclonal Antibody OAAB01841 ATG4C Antibody (OAAB01841) Human DB, ELISA 400ul $289 Details
Polyclonal Antibody ARP58426_P050 ATG4C Antibody (ARP58426_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Monoclonal Antibody OAAB06840 ATG4C antibody (OAAB06840) Mouse WB 400ul $289 Details
Polyclonal Antibody OAAB13575 ATG4C antibody - N - terminal region (OAAB13575) Human; Mouse WB, IHC 400ul $289 Details
Polyclonal Antibody OAAB13576 ATG4C antibody - center region (OAAB13576) Human WB, IHC 400ul $289 Details
Polyclonal Antibody OAAB13577 ATG4C antibody - C - terminal region (OAAB13577) Human; Mouse WB, IHC 400ul $289 Details
Polyclonal Antibody OAAB13578 ATG4C antibody (OAAB13578) Human WB, IHC 400ul $289 Details
Polyclonal Antibody OAAB13579 ATG4C antibody (OAAB13579) Human WB 400ul $289 Details
Polyclonal Antibody OAAB13580 ATG4C antibody (OAAB13580) Human WB, FC 400ul $289 Details
Polyclonal Antibody OAEC02511 ATG4C Antibody (OAEC02511) Human; Mouse WB, IHC, IF, ELISA 100ug $229 Details
Polyclonal Antibody OAAF03546 ATG4C Antibody (OAAF03546) Polyclonal Human, Mouse WB, IHC, IF, ELISA 100 ug $229 Details

Show all ATG4C antibodies


Product Images
ATG4C antibody - middle region (ARP58863_P050) in Human 721_B cells using Western Blot

Sample Type: Human 721_B

ATG4C antibody (OAAB06840) in Mouse Heart cells using Western Blot

Sample Type: Mouse Heart

ATG4C antibody - N - terminal region (OAAB13575) in 293 cells using Western Blot

Sample Type: 293

ATG4C antibody - N - terminal region (OAAB13575) in Human cancer, breast carcinoma, hepatocarcinoma cells using Immunohistochemistry

Sample Type: Human cancer, breast carcinoma, hepatocarcinoma

ATG4C antibody - N - terminal region (OAAB13575) in Jurkat cells using Western Blot

Sample Type: Jurkat

ATG4C antibody - N - terminal region (OAAB13575) in Mouse Liver cells using Western Blot

Sample Type: Mouse Liver

ATG4C Antibody (OAAF03546) in Human liver carcinoma cells using Immunohistochemistry

Sample Type: Human liver carcinoma

ATG4C Antibody (OAAF03546) in HuvEc cells using Immunofluorescence

Sample Type: HuvEc

ATG4C Antibody (OAAF03546) in K562, COS7 cells using Western Blot

Sample Type: K562, COS7

ATG4C Antibody (OAEC02511) in Human liver carcinoma cells using Immunohistochemistry

Sample Type: Human liver carcinoma

ATG4C Antibody (OAEC02511) in K562 cells using Western Blot

Sample Type: K562


ATG4C Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP58426 African clawed frog ATG4C antibody; Xenopus laevis ATG4C antibody Q5XH30 93.0%
ARP58426 African elephant ATG4C antibody; Loxodonta africana ATG4C antibody G3T356 93.0%
ARP58863 African elephant ATG4C antibody; Loxodonta africana ATG4C antibody G3T356 93.0%
ARP58863 African elephant ATG4C antibody; Loxodonta africana ATG4C antibody G3UCB0 93.0%
ARP58426 Bovine ATG4C antibody; Bos taurus ATG4C antibody A2VE68 86.0%
ARP58426 Bovine ATG4C antibody; Bos taurus ATG4C antibody F1MJ23 86.0%
ARP58426 Cat ATG4C antibody; Felis catus ATG4C antibody M3XAC8 93.0%
ARP58863 Cat ATG4C antibody; Felis catus ATG4C antibody M3XAC8 92.0%
ARP58426 Chicken ATG4C antibody; Gallus gallus ATG4C antibody E1BS34 93.0%
ARP58426 Chimpanzee ATG4C antibody; Pan troglodytes ATG4C antibody H2PZ58 100.0%
ARP58863 Chimpanzee ATG4C antibody; Pan troglodytes ATG4C antibody H2PZ58 100.0%
ARP58426 Chinese softshell turtle ATG4C antibody; Pelodiscus sinensis ATG4C antibody K7G446 85.0%
ARP58426 Collared flycatcher ATG4C antibody; Ficedula albicollis ATG4C antibody U3KDH4 93.0%
ARP58426 Common turkey ATG4C antibody; Meleagris gallopavo ATG4C antibody G1NGS6 93.0%
ARP58426 Dog ATG4C antibody; Canis familiaris ATG4C antibody E2R5A4 93.0%
ARP58863 Dog ATG4C antibody; Canis familiaris ATG4C antibody E2R5A4 91.0%
ARP58426 Domestic duck ATG4C antibody; Anas platyrhynchos ATG4C antibody U3J6Q4 93.0%
ARP58863 Domestic duck ATG4C antibody; Anas platyrhynchos ATG4C antibody U3J6Q4 89.0%
ARP58426 Duckbill platypus ATG4C antibody; Ornithorhynchus anatinus ATG4C antibody F6PL45 93.0%
ARP58426 European domestic ferret ATG4C antibody; Mustela putorius furo ATG4C antibody M3Y9B9 93.0%
ARP58863 European domestic ferret ATG4C antibody; Mustela putorius furo ATG4C antibody M3Y9B9 92.0%
ARP58426 Giant panda ATG4C antibody; Ailuropoda melanoleuca ATG4C antibody D2H7H2 93.0%
ARP58863 Giant panda ATG4C antibody; Ailuropoda melanoleuca ATG4C antibody D2H7H2 83.0%
ARP58426 Gray short-tailed opossum ATG4C antibody; Monodelphis domestica ATG4C antibody F7FIS5 93.0%
ARP58426 Green anole ATG4C antibody; Anolis carolinensis ATG4C antibody G1KHE1 79.0%
ARP58426 Horse ATG4C antibody; Equus caballus ATG4C antibody F6TTW5 93.0%
ARP58863 Horse ATG4C antibody; Equus caballus ATG4C antibody F6TTW5 86.0%
ARP58863 Human ATG4C antibody; Homo sapiens ATG4C antibody Q05D29 100.0%
ARP58426 Human ATG4C antibody; Homo sapiens ATG4C antibody Q96DT6 100.0%
ARP58863 Human ATG4C antibody; Homo sapiens ATG4C antibody Q96DT6 100.0%
ARP58426 Mouse ATG4C antibody; Mus musculus ATG4C antibody Q3UYA5 79.0%
ARP58426 Mouse ATG4C antibody; Mus musculus ATG4C antibody Q811C2 79.0%
ARP58426 Northern white-cheeked gibbon ATG4C antibody; Nomascus leucogenys ATG4C antibody G1RYH4 100.0%
ARP58863 Northern white-cheeked gibbon ATG4C antibody; Nomascus leucogenys ATG4C antibody G1RYH4 100.0%
ARP58426 Pig ATG4C antibody; Sus scrofa ATG4C antibody D7RA23 86.0%
ARP58426 Pig ATG4C antibody; Sus scrofa ATG4C antibody F1S810 86.0%
ARP58426 Rabbit ATG4C antibody; Oryctolagus cuniculus ATG4C antibody G1STL0 86.0%
ARP58426 Rat ATG4C antibody; Rattus norvegicus ATG4C antibody F1M3M0 86.0%
ARP58863 Rhesus macaque ATG4C antibody; Macaca mulatta ATG4C antibody F6X5Z7 93.0%
ARP58426 Rhesus macaque ATG4C antibody; Macaca mulatta ATG4C antibody F6X5Z7 86.0%
ARP58426 Small-eared galago ATG4C antibody; Otolemur garnettii ATG4C antibody H0WNZ4 93.0%
ARP58426 Sumatran orangutan ATG4C antibody; Pongo abelii ATG4C antibody H2N766 100.0%
ARP58863 Sumatran orangutan ATG4C antibody; Pongo abelii ATG4C antibody H2N766 100.0%
ARP58426 Tasmanian devil ATG4C antibody; Sarcophilus harrisii ATG4C antibody G3X197 93.0%
ARP58426 Western clawed frog ATG4C antibody; Xenopus tropicalis ATG4C antibody Q68EP9 93.0%
ARP58426 White-tufted-ear marmoset ATG4C antibody; Callithrix jacchus ATG4C antibody F6VRB1 93.0%
ARP58426 White-tufted-ear marmoset ATG4C antibody; Callithrix jacchus ATG4C antibody U3FGR8 93.0%
ARP58863 White-tufted-ear marmoset ATG4C antibody; Callithrix jacchus ATG4C antibody F6VR72 86.0%
ARP58863 White-tufted-ear marmoset ATG4C antibody; Callithrix jacchus ATG4C antibody F6VRB1 86.0%
ARP58863 White-tufted-ear marmoset ATG4C antibody; Callithrix jacchus ATG4C antibody U3FGR8 86.0%
ARP58426 Zebra finch ATG4C antibody; Taeniopygia guttata ATG4C antibody H0ZHX8 93.0%

Tissue & Cell Line Gene Expression Data