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Gene ID: 9311 | ASIC3 Antibody Resource


ASIC3 Antibody Resource
Gene Full Name: 
acid-sensing (proton-gated) ion channel 3
Uniprot: 
Q9UHC3
Protein Name: 
acid-sensing ion channel 3
Nucleotide: 
NM_020321
Alias: 
ACCN3;TNaC1;DRASIC;SLNAC1;
Ensembl: 
ENSG00000213199
Location: 
7q35
HPRD: 
10626
NCBI Gene: 
9311
MIM: 
611741

Summary: 
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]
Function: 
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties.
Subcellular location: 
Cell membrane; Multi-pass membrane protein. Cytoplasm. Note: Cell surface expression may be stabilized by interaction with LIN7B and cytoplasmic retention by interaction with DLG4. In part cytoplasmic in cochlea cells .
PTM: 
Disulfide bond;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP35152_T100 ACCN3 antibody - N-terminal region (ARP35152_T100) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rabbit, Rat IHC, WB 100ug $229 Details
Polyclonal Antibody ARP35301_P050 ASIC3 Antibody (ARP35301_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP35302_P050 ASIC3 Antibody (ARP35302_P050) Polyclonal Dog, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB14676 ACCN3 antibody - N - terminal region (OAAB14676) Human WB 400ul $289 Details

Show all ASIC3 antibodies


Product Images
ACCN3 antibody - N-terminal region (ARP35152_T100) in Human kidney cells using Immunohistochemistry

Sample Type: Human kidney

ACCN3 antibody - N-terminal region (ARP35152_T100) in Human Kidney cells using Western Blot

Sample Type: Human Kidney

ACCN3 antibody - N - terminal region (OAAB14676) in CEM cells using Western Blot

Sample Type: CEM


ASIC3 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP35152 Cat ASIC3 antibody; Felis catus ASIC3 antibody M3WNS3 87.0%
ARP35301 Cat ASIC3 antibody; Felis catus ASIC3 antibody M3WNS3 86.0%
ARP35302 Cat ASIC3 antibody; Felis catus ASIC3 antibody M3WNS3 86.0%
ARP35152 Chimpanzee ASIC3 antibody; Pan troglodytes ASIC3 antibody H2RDH5 100.0%
ARP35301 Chimpanzee ASIC3 antibody; Pan troglodytes ASIC3 antibody H2RDH5 100.0%
ARP35302 Chimpanzee ASIC3 antibody; Pan troglodytes ASIC3 antibody H2RDH5 100.0%
ARP35152 Dog ASIC3 antibody; Canis familiaris ASIC3 antibody E2RHH0 80.0%
ARP35301 Dog ASIC3 antibody; Canis familiaris ASIC3 antibody E2RHH0 79.0%
ARP35302 Dog ASIC3 antibody; Canis familiaris ASIC3 antibody E2RHH0 79.0%
ARP35152 Duckbill platypus ASIC3 antibody; Ornithorhynchus anatinus ASIC3 antibody F6RDV3 87.0%
ARP35301 Duckbill platypus ASIC3 antibody; Ornithorhynchus anatinus ASIC3 antibody F6RDV3 86.0%
ARP35302 Duckbill platypus ASIC3 antibody; Ornithorhynchus anatinus ASIC3 antibody F6RDV3 85.0%
ARP35152 European domestic ferret ASIC3 antibody; Mustela putorius furo ASIC3 antibody M3YA05 93.0%
ARP35301 European domestic ferret ASIC3 antibody; Mustela putorius furo ASIC3 antibody M3YA05 93.0%
ARP35302 European domestic ferret ASIC3 antibody; Mustela putorius furo ASIC3 antibody M3YA05 86.0%
ARP35152 Human ASIC3 antibody; Homo sapiens ASIC3 antibody Q9UHC3-2 100.0%
ARP35301 Human ASIC3 antibody; Homo sapiens ASIC3 antibody Q9UHC3-2 100.0%
ARP35302 Human ASIC3 antibody; Homo sapiens ASIC3 antibody Q9UHC3-2 100.0%
ARP35152 Human ASIC3 antibody; Homo sapiens ASIC3 antibody Q9UHC3-3 100.0%
ARP35301 Human ASIC3 antibody; Homo sapiens ASIC3 antibody Q9UHC3-3 100.0%
ARP35302 Human ASIC3 antibody; Homo sapiens ASIC3 antibody Q9UHC3-3 100.0%
ARP35152 Human ASIC3 antibody; Homo sapiens ASIC3 antibody Q9UHC3-4 100.0%
ARP35301 Human ASIC3 antibody; Homo sapiens ASIC3 antibody Q9UHC3-4 100.0%
ARP35302 Human ASIC3 antibody; Homo sapiens ASIC3 antibody Q9UHC3-4 100.0%
ARP35152 Human ASIC3 antibody; Homo sapiens ASIC3 antibody Q9UHC3 100.0%
ARP35301 Human ASIC3 antibody; Homo sapiens ASIC3 antibody Q9UHC3 100.0%
ARP35302 Human ASIC3 antibody; Homo sapiens ASIC3 antibody Q9UHC3 100.0%
ARP35152 Mouse ASIC3 antibody; Mus musculus ASIC3 antibody Q6X1Y6-2 87.0%
ARP35152 Mouse ASIC3 antibody; Mus musculus ASIC3 antibody Q6X1Y6 87.0%
ARP35301 Mouse ASIC3 antibody; Mus musculus ASIC3 antibody Q6X1Y6-2 86.0%
ARP35301 Mouse ASIC3 antibody; Mus musculus ASIC3 antibody Q6X1Y6 86.0%
ARP35288 Mouse ASIC3 antibody; Mus musculus ASIC3 antibody Q6X1Y6 79.0%
ARP35301 Pig ASIC3 antibody; Sus scrofa ASIC3 antibody I3L578 93.0%
ARP35152 Pig ASIC3 antibody; Sus scrofa ASIC3 antibody I3L578 87.0%
ARP35302 Pig ASIC3 antibody; Sus scrofa ASIC3 antibody I3L578 79.0%
ARP35152 Rabbit ASIC3 antibody; Oryctolagus cuniculus ASIC3 antibody G1TR51 87.0%
ARP35301 Rabbit ASIC3 antibody; Oryctolagus cuniculus ASIC3 antibody G1TR51 86.0%
ARP35302 Rabbit ASIC3 antibody; Oryctolagus cuniculus ASIC3 antibody G1TR51 86.0%
ARP35152 Rat ASIC3 antibody; Rattus norvegicus ASIC3 antibody O35240 87.0%
ARP35301 Rat ASIC3 antibody; Rattus norvegicus ASIC3 antibody O35240 86.0%
ARP35301 Small-eared galago ASIC3 antibody; Otolemur garnettii ASIC3 antibody H0XKA0 79.0%
ARP35152 Sumatran orangutan ASIC3 antibody; Pongo abelii ASIC3 antibody H2PP20 93.0%
ARP35301 Sumatran orangutan ASIC3 antibody; Pongo abelii ASIC3 antibody H2PP20 93.0%
ARP35302 Sumatran orangutan ASIC3 antibody; Pongo abelii ASIC3 antibody H2PP20 93.0%
ARP35152 Tasmanian devil ASIC3 antibody; Sarcophilus harrisii ASIC3 antibody G3W6Y0 80.0%
ARP35301 Tasmanian devil ASIC3 antibody; Sarcophilus harrisii ASIC3 antibody G3W6Y0 79.0%
ARP35301 Thirteen-lined ground squirrel ASIC3 antibody; Spermophilus tridecemlineatus ASIC3 antibody I3ND95 92.0%
ARP35152 Thirteen-lined ground squirrel ASIC3 antibody; Spermophilus tridecemlineatus ASIC3 antibody I3ND95 87.0%
ARP35152 White-tufted-ear marmoset ASIC3 antibody; Callithrix jacchus ASIC3 antibody F6ZWX9 87.0%
ARP35152 White-tufted-ear marmoset ASIC3 antibody; Callithrix jacchus ASIC3 antibody F6ZWY7 87.0%
ARP35152 White-tufted-ear marmoset ASIC3 antibody; Callithrix jacchus ASIC3 antibody F6ZX00 87.0%
ARP35301 White-tufted-ear marmoset ASIC3 antibody; Callithrix jacchus ASIC3 antibody F6ZWX9 86.0%
ARP35302 White-tufted-ear marmoset ASIC3 antibody; Callithrix jacchus ASIC3 antibody F6ZWX9 86.0%
ARP35301 White-tufted-ear marmoset ASIC3 antibody; Callithrix jacchus ASIC3 antibody F6ZWY7 86.0%
ARP35302 White-tufted-ear marmoset ASIC3 antibody; Callithrix jacchus ASIC3 antibody F6ZWY7 86.0%
ARP35301 White-tufted-ear marmoset ASIC3 antibody; Callithrix jacchus ASIC3 antibody F6ZX00 86.0%
ARP35302 White-tufted-ear marmoset ASIC3 antibody; Callithrix jacchus ASIC3 antibody F6ZX00 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas207561_s_at721_B_lymphoblasts6.5505.930Details
BioGPS Gene Atlas207561_s_atAdipocyte5.4005.930Details
BioGPS Gene Atlas207561_s_atAdrenalCortex6.0505.930Details
BioGPS Gene Atlas207561_s_atAdrenalgland4.8005.930Details
BioGPS Gene Atlas207561_s_atAmygdala6.0505.930Details
BioGPS Gene Atlas207561_s_atAppendix5.8505.930Details
BioGPS Gene Atlas207561_s_atAtrioventricularNode4.7505.930Details
BioGPS Gene Atlas207561_s_atBDCA4+_DentriticCells5.9005.930Details
BioGPS Gene Atlas207561_s_atBonemarrow6.0005.930Details
BioGPS Gene Atlas207561_s_atBronchialEpithelialCells5.5505.930Details
BioGPS Gene Atlas207561_s_atCD105+_Endothelial5.7505.930Details
BioGPS Gene Atlas207561_s_atCD14+_Monocytes6.0005.930Details
BioGPS Gene Atlas207561_s_atCD19+_BCells(neg._sel.)5.9505.930Details
BioGPS Gene Atlas207561_s_atCD33+_Myeloid7.3505.930Details
BioGPS Gene Atlas207561_s_atCD34+7.1005.930Details
BioGPS Gene Atlas207561_s_atCD4+_Tcells6.3005.930Details
BioGPS Gene Atlas207561_s_atCD56+_NKCells6.6005.930Details
BioGPS Gene Atlas207561_s_atCD71+_EarlyErythroid5.5505.930Details
BioGPS Gene Atlas207561_s_atCD8+_Tcells5.5505.930Details
BioGPS Gene Atlas207561_s_atCardiacMyocytes7.3505.930Details
BioGPS Gene Atlas207561_s_atCaudatenucleus5.1005.930Details
BioGPS Gene Atlas207561_s_atCerebellum4.6005.930Details
BioGPS Gene Atlas207561_s_atCerebellumPeduncles6.5505.930Details
BioGPS Gene Atlas207561_s_atCiliaryGanglion4.2505.930Details
BioGPS Gene Atlas207561_s_atCingulateCortex5.9505.930Details
BioGPS Gene Atlas207561_s_atColorectaladenocarcinoma5.6505.930Details
BioGPS Gene Atlas207561_s_atDorsalRootGanglion4.7005.930Details
BioGPS Gene Atlas207561_s_atFetalThyroid5.5505.930Details
BioGPS Gene Atlas207561_s_atFetalbrain5.6005.930Details
BioGPS Gene Atlas207561_s_atFetalliver4.9005.930Details
BioGPS Gene Atlas207561_s_atFetallung4.4005.930Details
BioGPS Gene Atlas207561_s_atGlobusPallidus4.4005.930Details
BioGPS Gene Atlas207561_s_atHeart8.2505.930Details
BioGPS Gene Atlas207561_s_atHypothalamus6.0505.930Details
BioGPS Gene Atlas207561_s_atKidney4.7505.930Details
BioGPS Gene Atlas207561_s_atLeukemia_chronicMyelogenousK-5626.2505.930Details
BioGPS Gene Atlas207561_s_atLeukemia_promyelocytic-HL-605.0505.930Details
BioGPS Gene Atlas207561_s_atLeukemialymphoblastic(MOLT-4)4.4005.930Details
BioGPS Gene Atlas207561_s_atLiver7.5005.930Details
BioGPS Gene Atlas207561_s_atLung6.2005.930Details
BioGPS Gene Atlas207561_s_atLymphnode4.7005.930Details
BioGPS Gene Atlas207561_s_atLymphoma_burkitts(Daudi)7.2505.930Details
BioGPS Gene Atlas207561_s_atLymphoma_burkitts(Raji)8.0505.930Details
BioGPS Gene Atlas207561_s_atMedullaOblongata5.2005.930Details
BioGPS Gene Atlas207561_s_atOccipitalLobe5.1505.930Details
BioGPS Gene Atlas207561_s_atOlfactoryBulb4.4505.930Details
BioGPS Gene Atlas207561_s_atOvary3.9505.930Details
BioGPS Gene Atlas207561_s_atPancreas4.6505.930Details
BioGPS Gene Atlas207561_s_atPancreaticIslet6.0505.930Details
BioGPS Gene Atlas207561_s_atParietalLobe6.0505.930Details
BioGPS Gene Atlas207561_s_atPituitary6.6505.930Details
BioGPS Gene Atlas207561_s_atPlacenta5.7505.930Details
BioGPS Gene Atlas207561_s_atPons6.9505.930Details
BioGPS Gene Atlas207561_s_atPrefrontalCortex10.7005.930Details
BioGPS Gene Atlas207561_s_atProstate6.5505.930Details
BioGPS Gene Atlas207561_s_atSalivarygland4.5505.930Details
BioGPS Gene Atlas207561_s_atSkeletalMuscle7.2505.930Details
BioGPS Gene Atlas207561_s_atSkin4.5505.930Details
BioGPS Gene Atlas207561_s_atSmoothMuscle6.1505.930Details
BioGPS Gene Atlas207561_s_atSpinalcord7.6005.930Details
BioGPS Gene Atlas207561_s_atSubthalamicNucleus5.2005.930Details
BioGPS Gene Atlas207561_s_atSuperiorCervicalGanglion7.2005.930Details
BioGPS Gene Atlas207561_s_atTemporalLobe5.2505.930Details
BioGPS Gene Atlas207561_s_atTestis4.9005.930Details
BioGPS Gene Atlas207561_s_atTestisGermCell5.2505.930Details
BioGPS Gene Atlas207561_s_atTestisIntersitial4.8005.930Details
BioGPS Gene Atlas207561_s_atTestisLeydigCell7.0505.930Details
BioGPS Gene Atlas207561_s_atTestisSeminiferousTubule5.0005.930Details
BioGPS Gene Atlas207561_s_atThalamus5.7505.930Details
BioGPS Gene Atlas207561_s_atThymus4.2005.930Details
BioGPS Gene Atlas207561_s_atThyroid6.8505.930Details
BioGPS Gene Atlas207561_s_atTongue5.5005.930Details
BioGPS Gene Atlas207561_s_atTonsil5.5505.930Details
BioGPS Gene Atlas207561_s_atTrachea4.7505.930Details
BioGPS Gene Atlas207561_s_atTrigeminalGanglion6.1005.930Details
BioGPS Gene Atlas207561_s_atUterus4.4505.930Details
BioGPS Gene Atlas207561_s_atUterusCorpus5.9505.930Details
BioGPS Gene Atlas207561_s_atWholeBlood5.9505.930Details
BioGPS Gene Atlas207561_s_atWholebrain4.7005.930Details
BioGPS Gene Atlas207561_s_atcolon5.7505.930Details
BioGPS Gene Atlas207561_s_atpineal_day8.7405.930Details
BioGPS Gene Atlas207561_s_atpineal_night7.0405.930Details
BioGPS Gene Atlas207561_s_atretina7.0755.930Details
BioGPS Gene Atlas207561_s_atsmall_intestine5.4005.930Details
BioGPS NCI60207561_s_at7865.6435.570Details
BioGPS NCI60207561_s_atA1725.3565.570Details
BioGPS NCI60207561_s_atA2045.4995.570Details
BioGPS NCI60207561_s_atA3615.5825.570Details
BioGPS NCI60207561_s_atA4985.5495.570Details
BioGPS NCI60207561_s_atA5495.7615.570Details
BioGPS NCI60207561_s_atACC36.0105.570Details
BioGPS NCI60207561_s_atACHN5.3515.570Details
BioGPS NCI60207561_s_atALVA315.7275.570Details
BioGPS NCI60207561_s_atCAKI15.8855.570Details
BioGPS NCI60207561_s_atCCRT CEM6.5825.570Details
BioGPS NCI60207561_s_atCOLO2055.5485.570Details
BioGPS NCI60207561_s_atDLD15.4875.570Details
BioGPS NCI60207561_s_atDU1455.2925.570Details
BioGPS NCI60207561_s_atEKVX5.1915.570Details
BioGPS NCI60207561_s_atGM1335.6665.570Details
BioGPS NCI60207561_s_atGM16005.7315.570Details
BioGPS NCI60207561_s_atGM23135.6205.570Details
BioGPS NCI60207561_s_atGM23455.5525.570Details
BioGPS NCI60207561_s_atGM24935.7345.570Details
BioGPS NCI60207561_s_atGM976.5005.570Details
BioGPS NCI60207561_s_atHCC29985.2915.570Details
BioGPS NCI60207561_s_atHCT1165.5545.570Details
BioGPS NCI60207561_s_atHCT155.0785.570Details
BioGPS NCI60207561_s_atHEK 293 T-rex5.7265.570Details
BioGPS NCI60207561_s_atHEK 293T5.5485.570Details
BioGPS NCI60207561_s_atHEK2935.5515.570Details
BioGPS NCI60207561_s_atHELA5.2855.570Details
BioGPS NCI60207561_s_atHEPG25.5255.570Details
BioGPS NCI60207561_s_atHL606.1485.570Details
BioGPS NCI60207561_s_atHOP625.5465.570Details
BioGPS NCI60207561_s_atHOP925.2895.570Details
BioGPS NCI60207561_s_atHS578T5.4255.570Details
BioGPS NCI60207561_s_atHSG5.4395.570Details
BioGPS NCI60207561_s_atHT10805.4445.570Details
BioGPS NCI60207561_s_atHT296.2405.570Details
BioGPS NCI60207561_s_atIGROV15.5015.570Details
BioGPS NCI60207561_s_atIOSE805.5445.570Details
BioGPS NCI60207561_s_atJURKAT5.5325.570Details
BioGPS NCI60207561_s_atK5626.1865.570Details
BioGPS NCI60207561_s_atKM125.8795.570Details
BioGPS NCI60207561_s_atLN185.1465.570Details
BioGPS NCI60207561_s_atLNCAP5.5295.570Details
BioGPS NCI60207561_s_atLOX IMVI5.5265.570Details
BioGPS NCI60207561_s_atM145.5005.570Details
BioGPS NCI60207561_s_atMALME 3M6.1785.570Details
BioGPS NCI60207561_s_atMCF75.3135.570Details
BioGPS NCI60207561_s_atMD MB2315.5675.570Details
BioGPS NCI60207561_s_atMDA MB4355.7435.570Details
BioGPS NCI60207561_s_atMOLT45.9295.570Details
BioGPS NCI60207561_s_atNCI 4605.6295.570Details
BioGPS NCI60207561_s_atNCI H2265.7565.570Details
BioGPS NCI60207561_s_atNCI H235.5805.570Details
BioGPS NCI60207561_s_atNCI H322M5.5305.570Details
BioGPS NCI60207561_s_atNCVADR RES5.2975.570Details
BioGPS NCI60207561_s_atOVCAR35.7085.570Details
BioGPS NCI60207561_s_atOVCAR45.5185.570Details
BioGPS NCI60207561_s_atOVCAR55.4005.570Details
BioGPS NCI60207561_s_atOVCAR85.0475.570Details
BioGPS NCI60207561_s_atPANC15.5715.570Details
BioGPS NCI60207561_s_atRL75.6125.570Details
BioGPS NCI60207561_s_atRPMI 82265.5895.570Details
BioGPS NCI60207561_s_atRS118465.9845.570Details
BioGPS NCI60207561_s_atRXF3935.5245.570Details
BioGPS NCI60207561_s_atSAOS25.5815.570Details
BioGPS NCI60207561_s_atSF2685.5325.570Details
BioGPS NCI60207561_s_atSF2955.4035.570Details
BioGPS NCI60207561_s_atSF5395.3595.570Details
BioGPS NCI60207561_s_atSHSYSY+RA5.4375.570Details
BioGPS NCI60207561_s_atSHSYSY-RA5.5095.570Details
BioGPS NCI60207561_s_atSKMEL25.4695.570Details
BioGPS NCI60207561_s_atSKMEL285.5595.570Details
BioGPS NCI60207561_s_atSKMEL55.3495.570Details
BioGPS NCI60207561_s_atSKOV35.6435.570Details
BioGPS NCI60207561_s_atSN12C5.4475.570Details
BioGPS NCI60207561_s_atSNB195.3085.570Details
BioGPS NCI60207561_s_atSNB755.5275.570Details
BioGPS NCI60207561_s_atSR5.6115.570Details
BioGPS NCI60207561_s_atSW6205.5355.570Details
BioGPS NCI60207561_s_atT245.6245.570Details
BioGPS NCI60207561_s_atT3M45.8565.570Details
BioGPS NCI60207561_s_atTK105.5075.570Details
BioGPS NCI60207561_s_atU1185.2765.570Details
BioGPS NCI60207561_s_atU1385.0195.570Details
BioGPS NCI60207561_s_atU20S5.4895.570Details
BioGPS NCI60207561_s_atU2515.4905.570Details
BioGPS NCI60207561_s_atU875.2055.570Details
BioGPS NCI60207561_s_atUACC2575.4815.570Details
BioGPS NCI60207561_s_atUACC625.6015.570Details
BioGPS NCI60207561_s_atUO315.2905.570Details
BioGPS NCI60207561_s_atZR75_16.6595.570Details
BioGPS NCI60207561_s_atastrocytes5.6115.570Details
BioGPS NCI60207561_s_athuh-75.7425.570Details