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Gene ID: 51008 | Ascc1 Antibody Resource


Ascc1 Antibody Resource
Gene Full Name: 
activating signal cointegrator 1 complex subunit 1
Uniprot: 
Q8N9N2
Protein Name: 
activating signal cointegrator 1 complex subunit 1
Nucleotide: 
NR_045564
Alias: 
p50;CGI-18;ASC1p50;
Ensembl: 
Location: 
10pter-q25.3
HPRD: 
NCBI Gene: 
51008
MIM: 
614215

Summary: 
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Function: 
Enhances NF-kappa-B, SRF and AP1 transactivation. In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin.
Subcellular location: 
Cytoplasm.
PTM: 
Disease: 
Barrett esophagus (BE) [MIM:614266]: A condition characterized by a metaplastic change in which normal esophageal squamous epithelium is replaced by a columnar and intestinal-type epithelium. Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement of acid and bile salts from the stomach into the esophagus causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes. Note: The gene represented in this entry may be involved in disease pathogenesis.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP56782_P050 Ascc1 antibody - C-terminal region (ARP56782_P050) Polyclonal Bovine, Dog, Goat, Guinea pig, Human, Mouse, Rabbit, Rat WB 50ug $289 Details
Polyclonal Antibody ARP56783_P050 Ascc1 antibody - C-terminal region (ARP56783_P050) Polyclonal Bovine, Dog, Goat, Human, Mouse, Rabbit, Rat WB 50ug $289 Details
Polyclonal Antibody OAAB00126 ASCC1 antibody - N-terminal region (OAAB00126) Human WB, ELISA 400ul $289 Details

Show all Ascc1 antibodies


Product Images
Ascc1 antibody - C-terminal region (ARP56782_P050) in Rat Muscle cells using Western Blot

Sample Type: Rat Muscle

Ascc1 antibody - C-terminal region (ARP56783_P050) in Rat Liver cells using Western Blot

Sample Type: Rat Liver


Ascc1 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP56782 Bovine Ascc1 antibody; Bos taurus Ascc1 antibody Q0IIJ9 100.0%
ARP56783 Bovine Ascc1 antibody; Bos taurus Ascc1 antibody Q0IIJ9 100.0%
ARP56782 Cat Ascc1 antibody; Felis catus Ascc1 antibody M3X6F0 100.0%
ARP56783 Cat Ascc1 antibody; Felis catus Ascc1 antibody M3X6F0 100.0%
ARP56782 Chimpanzee Ascc1 antibody; Pan troglodytes Ascc1 antibody H2Q224 100.0%
ARP56783 Chimpanzee Ascc1 antibody; Pan troglodytes Ascc1 antibody H2Q224 100.0%
ARP56782 Dog Ascc1 antibody; Canis familiaris Ascc1 antibody E2RKL0 100.0%
ARP56783 Dog Ascc1 antibody; Canis familiaris Ascc1 antibody E2RKL0 100.0%
ARP56782 Dog Ascc1 antibody; Canis familiaris Ascc1 antibody J9NUQ6 100.0%
ARP56783 Dog Ascc1 antibody; Canis familiaris Ascc1 antibody J9NUQ6 100.0%
ARP56782 European domestic ferret Ascc1 antibody; Mustela putorius furo Ascc1 antibody M3XYA3 100.0%
ARP56783 European domestic ferret Ascc1 antibody; Mustela putorius furo Ascc1 antibody M3XYA3 100.0%
ARP56783 Goat Ascc1 antibody; Capra hircus Ascc1 antibody G1DG55 100.0%
ARP56782 Goat Ascc1 antibody; Capra hircus Ascc1 antibody G1DG55 86.0%
ARP56782 Horse Ascc1 antibody; Equus caballus Ascc1 antibody F7AZ56 100.0%
ARP56783 Horse Ascc1 antibody; Equus caballus Ascc1 antibody F7AZ56 100.0%
ARP56782 Human Ascc1 antibody; Homo sapiens Ascc1 antibody F5H874 100.0%
ARP56783 Human Ascc1 antibody; Homo sapiens Ascc1 antibody F5H874 100.0%
ARP56782 Human Ascc1 antibody; Homo sapiens Ascc1 antibody H0YCB3 100.0%
ARP56782 Human Ascc1 antibody; Homo sapiens Ascc1 antibody H0YE76 100.0%
ARP56782 Human Ascc1 antibody; Homo sapiens Ascc1 antibody H0YER2 100.0%
ARP56782 Human Ascc1 antibody; Homo sapiens Ascc1 antibody Q8N9N2-2 100.0%
ARP56783 Human Ascc1 antibody; Homo sapiens Ascc1 antibody Q8N9N2-2 100.0%
ARP56782 Human Ascc1 antibody; Homo sapiens Ascc1 antibody Q8N9N2 100.0%
ARP46168 Human Ascc1 antibody; Homo sapiens Ascc1 antibody H0YCB3 86.0%
ARP46168 Human Ascc1 antibody; Homo sapiens Ascc1 antibody Q8N9N2 86.0%
ARP56782 Mouse Ascc1 antibody; Mus musculus Ascc1 antibody Q9D8Z1 100.0%
ARP56783 Mouse Ascc1 antibody; Mus musculus Ascc1 antibody Q9D8Z1 100.0%
ARP56782 Pig Ascc1 antibody; Sus scrofa Ascc1 antibody I3L6H8 100.0%
ARP56783 Pig Ascc1 antibody; Sus scrofa Ascc1 antibody I3L6H8 100.0%
ARP56782 Pig Ascc1 antibody; Sus scrofa Ascc1 antibody I3LBQ6 100.0%
ARP56783 Rabbit Ascc1 antibody; Oryctolagus cuniculus Ascc1 antibody G1TWT4 100.0%
ARP56782 Rabbit Ascc1 antibody; Oryctolagus cuniculus Ascc1 antibody G1TWT4 93.0%
ARP56782 Rat Ascc1 antibody; Rattus norvegicus Ascc1 antibody G3V619 100.0%
ARP56783 Rat Ascc1 antibody; Rattus norvegicus Ascc1 antibody G3V619 100.0%
ARP56782 Rhesus macaque Ascc1 antibody; Macaca mulatta Ascc1 antibody F7A2N9 100.0%
ARP56783 Rhesus macaque Ascc1 antibody; Macaca mulatta Ascc1 antibody F7A2N9 93.0%
ARP56782 Small-eared galago Ascc1 antibody; Otolemur garnettii Ascc1 antibody H0WXZ1 100.0%
ARP56783 Small-eared galago Ascc1 antibody; Otolemur garnettii Ascc1 antibody H0WXZ1 93.0%
ARP56782 Sumatran orangutan Ascc1 antibody; Pongo abelii Ascc1 antibody H2NAL7 100.0%
ARP56783 Sumatran orangutan Ascc1 antibody; Pongo abelii Ascc1 antibody H2NAL7 100.0%
ARP56782 Thirteen-lined ground squirrel Ascc1 antibody; Spermophilus tridecemlineatus Ascc1 antibody I3LX56 100.0%
ARP56783 Thirteen-lined ground squirrel Ascc1 antibody; Spermophilus tridecemlineatus Ascc1 antibody I3LX56 100.0%
ARP56782 White-tufted-ear marmoset Ascc1 antibody; Callithrix jacchus Ascc1 antibody F6YFM6 100.0%
ARP56782 White-tufted-ear marmoset Ascc1 antibody; Callithrix jacchus Ascc1 antibody F6YXT7 100.0%
ARP56782 White-tufted-ear marmoset Ascc1 antibody; Callithrix jacchus Ascc1 antibody U3CD38 100.0%
ARP56783 White-tufted-ear marmoset Ascc1 antibody; Callithrix jacchus Ascc1 antibody U3CD38 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas219336_s_at721_B_lymphoblasts40.45011.610Details
BioGPS Gene Atlas219336_s_atAdipocyte8.90011.610Details
BioGPS Gene Atlas219336_s_atAdrenalCortex13.65011.610Details
BioGPS Gene Atlas219336_s_atAdrenalgland13.20011.610Details
BioGPS Gene Atlas219336_s_atAmygdala10.35011.610Details
BioGPS Gene Atlas219336_s_atAppendix9.45011.610Details
BioGPS Gene Atlas219336_s_atAtrioventricularNode9.35011.610Details
BioGPS Gene Atlas219336_s_atBDCA4+_DentriticCells33.50011.610Details
BioGPS Gene Atlas219336_s_atBonemarrow9.05011.610Details
BioGPS Gene Atlas219336_s_atBronchialEpithelialCells9.80011.610Details
BioGPS Gene Atlas219336_s_atCD105+_Endothelial9.35011.610Details
BioGPS Gene Atlas219336_s_atCD14+_Monocytes9.10011.610Details
BioGPS Gene Atlas219336_s_atCD19+_BCells(neg._sel.)27.10011.610Details
BioGPS Gene Atlas219336_s_atCD33+_Myeloid20.40011.610Details
BioGPS Gene Atlas219336_s_atCD34+14.30011.610Details
BioGPS Gene Atlas219336_s_atCD4+_Tcells10.05011.610Details
BioGPS Gene Atlas219336_s_atCD56+_NKCells27.75011.610Details
BioGPS Gene Atlas219336_s_atCD71+_EarlyErythroid6.40011.610Details
BioGPS Gene Atlas219336_s_atCD8+_Tcells9.85011.610Details
BioGPS Gene Atlas219336_s_atCardiacMyocytes7.85011.610Details
BioGPS Gene Atlas219336_s_atCaudatenucleus11.95011.610Details
BioGPS Gene Atlas219336_s_atCerebellum7.45011.610Details
BioGPS Gene Atlas219336_s_atCerebellumPeduncles11.60011.610Details
BioGPS Gene Atlas219336_s_atCiliaryGanglion8.10011.610Details
BioGPS Gene Atlas219336_s_atCingulateCortex11.95011.610Details
BioGPS Gene Atlas219336_s_atColorectaladenocarcinoma5.00011.610Details
BioGPS Gene Atlas219336_s_atDorsalRootGanglion8.20011.610Details
BioGPS Gene Atlas219336_s_atFetalThyroid8.15011.610Details
BioGPS Gene Atlas219336_s_atFetalbrain10.30011.610Details
BioGPS Gene Atlas219336_s_atFetalliver6.20011.610Details
BioGPS Gene Atlas219336_s_atFetallung5.95011.610Details
BioGPS Gene Atlas219336_s_atGlobusPallidus9.50011.610Details
BioGPS Gene Atlas219336_s_atHeart12.50011.610Details
BioGPS Gene Atlas219336_s_atHypothalamus19.90011.610Details
BioGPS Gene Atlas219336_s_atKidney8.20011.610Details
BioGPS Gene Atlas219336_s_atLeukemia_chronicMyelogenousK-56213.50011.610Details
BioGPS Gene Atlas219336_s_atLeukemia_promyelocytic-HL-6014.90011.610Details
BioGPS Gene Atlas219336_s_atLeukemialymphoblastic(MOLT-4)10.95011.610Details
BioGPS Gene Atlas219336_s_atLiver8.75011.610Details
BioGPS Gene Atlas219336_s_atLung8.90011.610Details
BioGPS Gene Atlas219336_s_atLymphnode6.70011.610Details
BioGPS Gene Atlas219336_s_atLymphoma_burkitts(Daudi)14.00011.610Details
BioGPS Gene Atlas219336_s_atLymphoma_burkitts(Raji)12.30011.610Details
BioGPS Gene Atlas219336_s_atMedullaOblongata8.35011.610Details
BioGPS Gene Atlas219336_s_atOccipitalLobe10.15011.610Details
BioGPS Gene Atlas219336_s_atOlfactoryBulb13.70011.610Details
BioGPS Gene Atlas219336_s_atOvary8.40011.610Details
BioGPS Gene Atlas219336_s_atPancreas7.90011.610Details
BioGPS Gene Atlas219336_s_atPancreaticIslet14.80011.610Details
BioGPS Gene Atlas219336_s_atParietalLobe14.65011.610Details
BioGPS Gene Atlas219336_s_atPituitary15.05011.610Details
BioGPS Gene Atlas219336_s_atPlacenta7.45011.610Details
BioGPS Gene Atlas219336_s_atPons7.35011.610Details
BioGPS Gene Atlas219336_s_atPrefrontalCortex12.10011.610Details
BioGPS Gene Atlas219336_s_atProstate6.85011.610Details
BioGPS Gene Atlas219336_s_atSalivarygland7.65011.610Details
BioGPS Gene Atlas219336_s_atSkeletalMuscle10.00011.610Details
BioGPS Gene Atlas219336_s_atSkin6.35011.610Details
BioGPS Gene Atlas219336_s_atSmoothMuscle11.30011.610Details
BioGPS Gene Atlas219336_s_atSpinalcord16.25011.610Details
BioGPS Gene Atlas219336_s_atSubthalamicNucleus10.90011.610Details
BioGPS Gene Atlas219336_s_atSuperiorCervicalGanglion10.90011.610Details
BioGPS Gene Atlas219336_s_atTemporalLobe8.55011.610Details
BioGPS Gene Atlas219336_s_atTestis14.40011.610Details
BioGPS Gene Atlas219336_s_atTestisGermCell9.80011.610Details
BioGPS Gene Atlas219336_s_atTestisIntersitial9.20011.610Details
BioGPS Gene Atlas219336_s_atTestisLeydigCell9.10011.610Details
BioGPS Gene Atlas219336_s_atTestisSeminiferousTubule10.20011.610Details
BioGPS Gene Atlas219336_s_atThalamus11.15011.610Details
BioGPS Gene Atlas219336_s_atThymus6.55011.610Details
BioGPS Gene Atlas219336_s_atThyroid8.55011.610Details
BioGPS Gene Atlas219336_s_atTongue9.10011.610Details
BioGPS Gene Atlas219336_s_atTonsil9.30011.610Details
BioGPS Gene Atlas219336_s_atTrachea6.85011.610Details
BioGPS Gene Atlas219336_s_atTrigeminalGanglion10.35011.610Details
BioGPS Gene Atlas219336_s_atUterus5.60011.610Details
BioGPS Gene Atlas219336_s_atUterusCorpus7.70011.610Details
BioGPS Gene Atlas219336_s_atWholeBlood6.10011.610Details
BioGPS Gene Atlas219336_s_atWholebrain9.50011.610Details
BioGPS Gene Atlas219336_s_atcolon4.70011.610Details
BioGPS Gene Atlas219336_s_atpineal_day14.72011.610Details
BioGPS Gene Atlas219336_s_atpineal_night19.66011.610Details
BioGPS Gene Atlas219336_s_atretina18.95011.610Details
BioGPS Gene Atlas219336_s_atsmall_intestine6.10011.610Details
BioGPS NCI60219336_s_at786450.601202.930Details
BioGPS NCI60219336_s_atA172463.234202.930Details
BioGPS NCI60219336_s_atA20466.253202.930Details
BioGPS NCI60219336_s_atA36147.995202.930Details
BioGPS NCI60219336_s_atA498285.754202.930Details
BioGPS NCI60219336_s_atA549523.842202.930Details
BioGPS NCI60219336_s_atACC3309.016202.930Details
BioGPS NCI60219336_s_atACHN289.213202.930Details
BioGPS NCI60219336_s_atALVA3195.329202.930Details
BioGPS NCI60219336_s_atCAKI1374.761202.930Details
BioGPS NCI60219336_s_atCCRT CEM66.420202.930Details
BioGPS NCI60219336_s_atCOLO205291.173202.930Details
BioGPS NCI60219336_s_atDLD1121.193202.930Details
BioGPS NCI60219336_s_atDU145159.130202.930Details
BioGPS NCI60219336_s_atEKVX334.234202.930Details
BioGPS NCI60219336_s_atGM133175.956202.930Details
BioGPS NCI60219336_s_atGM160026.007202.930Details
BioGPS NCI60219336_s_atGM2313234.739202.930Details
BioGPS NCI60219336_s_atGM234575.164202.930Details
BioGPS NCI60219336_s_atGM249360.862202.930Details
BioGPS NCI60219336_s_atGM9742.428202.930Details
BioGPS NCI60219336_s_atHCC2998515.666202.930Details
BioGPS NCI60219336_s_atHCT116125.779202.930Details
BioGPS NCI60219336_s_atHCT15355.707202.930Details
BioGPS NCI60219336_s_atHEK 293 T-rex176.673202.930Details
BioGPS NCI60219336_s_atHEK 293T182.340202.930Details
BioGPS NCI60219336_s_atHEK29397.036202.930Details
BioGPS NCI60219336_s_atHELA294.641202.930Details
BioGPS NCI60219336_s_atHEPG2291.752202.930Details
BioGPS NCI60219336_s_atHL60144.221202.930Details
BioGPS NCI60219336_s_atHOP62140.942202.930Details
BioGPS NCI60219336_s_atHOP92176.491202.930Details
BioGPS NCI60219336_s_atHS578T133.477202.930Details
BioGPS NCI60219336_s_atHSG128.033202.930Details
BioGPS NCI60219336_s_atHT108070.684202.930Details
BioGPS NCI60219336_s_atHT29117.469202.930Details
BioGPS NCI60219336_s_atIGROV1232.365202.930Details
BioGPS NCI60219336_s_atIOSE80128.332202.930Details
BioGPS NCI60219336_s_atJURKAT317.435202.930Details
BioGPS NCI60219336_s_atK562162.272202.930Details
BioGPS NCI60219336_s_atKM12131.727202.930Details
BioGPS NCI60219336_s_atLN18217.528202.930Details
BioGPS NCI60219336_s_atLNCAP199.339202.930Details
BioGPS NCI60219336_s_atLOX IMVI89.437202.930Details
BioGPS NCI60219336_s_atM14125.409202.930Details
BioGPS NCI60219336_s_atMALME 3M53.919202.930Details
BioGPS NCI60219336_s_atMCF7302.770202.930Details
BioGPS NCI60219336_s_atMD MB231163.683202.930Details
BioGPS NCI60219336_s_atMDA MB43571.587202.930Details
BioGPS NCI60219336_s_atMOLT4345.849202.930Details
BioGPS NCI60219336_s_atNCI 460441.364202.930Details
BioGPS NCI60219336_s_atNCI H2261056.050202.930Details
BioGPS NCI60219336_s_atNCI H23392.795202.930Details
BioGPS NCI60219336_s_atNCI H322M307.717202.930Details
BioGPS NCI60219336_s_atNCVADR RES117.843202.930Details
BioGPS NCI60219336_s_atOVCAR3154.759202.930Details
BioGPS NCI60219336_s_atOVCAR4496.825202.930Details
BioGPS NCI60219336_s_atOVCAR5231.308202.930Details
BioGPS NCI60219336_s_atOVCAR8111.086202.930Details
BioGPS NCI60219336_s_atPANC1775.410202.930Details
BioGPS NCI60219336_s_atRL7379.975202.930Details
BioGPS NCI60219336_s_atRPMI 8226144.319202.930Details
BioGPS NCI60219336_s_atRS11846194.863202.930Details
BioGPS NCI60219336_s_atRXF393248.879202.930Details
BioGPS NCI60219336_s_atSAOS260.594202.930Details
BioGPS NCI60219336_s_atSF26865.690202.930Details
BioGPS NCI60219336_s_atSF29544.601202.930Details
BioGPS NCI60219336_s_atSF53936.163202.930Details
BioGPS NCI60219336_s_atSHSYSY+RA133.361202.930Details
BioGPS NCI60219336_s_atSHSYSY-RA107.338202.930Details
BioGPS NCI60219336_s_atSKMEL251.749202.930Details
BioGPS NCI60219336_s_atSKMEL2853.873202.930Details
BioGPS NCI60219336_s_atSKMEL5115.162202.930Details
BioGPS NCI60219336_s_atSKOV3300.445202.930Details
BioGPS NCI60219336_s_atSN12C250.966202.930Details
BioGPS NCI60219336_s_atSNB1991.319202.930Details
BioGPS NCI60219336_s_atSNB7572.913202.930Details
BioGPS NCI60219336_s_atSR50.219202.930Details
BioGPS NCI60219336_s_atSW620319.602202.930Details
BioGPS NCI60219336_s_atT2471.405202.930Details
BioGPS NCI60219336_s_atT3M494.923202.930Details
BioGPS NCI60219336_s_atTK10106.499202.930Details
BioGPS NCI60219336_s_atU118127.196202.930Details
BioGPS NCI60219336_s_atU13894.475202.930Details
BioGPS NCI60219336_s_atU20S88.843202.930Details
BioGPS NCI60219336_s_atU25188.002202.930Details
BioGPS NCI60219336_s_atU87186.227202.930Details
BioGPS NCI60219336_s_atUACC25773.621202.930Details
BioGPS NCI60219336_s_atUACC6280.488202.930Details
BioGPS NCI60219336_s_atUO31130.556202.930Details
BioGPS NCI60219336_s_atZR75_159.681202.930Details
BioGPS NCI60219336_s_atastrocytes129.515202.930Details
BioGPS NCI60219336_s_athuh-7154.787202.930Details