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Gene ID: 136371 | ASB10 Antibody Resource


ASB10 Antibody Resource
Gene Full Name: 
ankyrin repeat and SOCS box containing 10
Uniprot: 
Q8WXI3
Protein Name: 
ankyrin repeat and SOCS box protein 10
Nucleotide: 
NM_080871
Alias: 
GLC1F;
Ensembl: 
ENSG00000146926
Location: 
7q36.1
HPRD: 
NCBI Gene: 
136371
MIM: 
615054

Summary: 
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. The SOCS box serves to couple suppressor of cytokine signaling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2008]
Function: 
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins .
Subcellular location: 
Cytoplasm. Nucleus. Note: In the ciliary body, it is detected in the cytoplasm and perinuclear region of the pigmented ciliary epithelial layer. In the retina, it is detected in the nuclei of retinal ganglion cells.
PTM: 
Disease: 
Glaucoma 1, open angle, F (GLC1F) [MIM:603383]: A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. However, glaucoma can occur at any intraocular pressure. The disease is generally asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB13060 ASB10 antibody - N - terminal region (OAAB13060) Human WB 400ul $289 Details

Show all ASB10 antibodies


Product Images
ASB10 antibody - N - terminal region (OAAB13060) in K562 cells using Western Blot

Sample Type: K562


ASB10 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP69286 Bovine ASB10 antibody; Bos taurus ASB10 antibody E1BB00 100.0%
ARP69286 Cat ASB10 antibody; Felis catus ASB10 antibody M3WIE8 100.0%
ARP69286 Chimpanzee ASB10 antibody; Pan troglodytes ASB10 antibody H2QVM8 100.0%
ARP69286 Dog ASB10 antibody; Canis familiaris ASB10 antibody F1PCX2 100.0%
ARP69286 Duckbill platypus ASB10 antibody; Ornithorhynchus anatinus ASB10 antibody F7B5U6 87.0%
ARP69286 European domestic ferret ASB10 antibody; Mustela putorius furo ASB10 antibody M3YBM2 93.0%
ARP69286 Giant panda ASB10 antibody; Ailuropoda melanoleuca ASB10 antibody D2H1V5 100.0%
ARP69286 Horse ASB10 antibody; Equus caballus ASB10 antibody F6S6P0 100.0%
ARP69286 Human ASB10 antibody; Homo sapiens ASB10 antibody D5MNW9 100.0%
ARP69286 Human ASB10 antibody; Homo sapiens ASB10 antibody J3KQJ5 100.0%
ARP69286 Human ASB10 antibody; Homo sapiens ASB10 antibody Q8WXI3-2 100.0%
ARP69286 Human ASB10 antibody; Homo sapiens ASB10 antibody Q8WXI3-3 100.0%
ARP69286 Human ASB10 antibody; Homo sapiens ASB10 antibody Q8WXI3 100.0%
ARP69286 Mouse ASB10 antibody; Mus musculus ASB10 antibody D3YU18 93.0%
ARP69286 Mouse ASB10 antibody; Mus musculus ASB10 antibody D3Z651 93.0%
ARP69286 Mouse ASB10 antibody; Mus musculus ASB10 antibody Q91ZT7 93.0%
ARP69286 Northern white-cheeked gibbon ASB10 antibody; Nomascus leucogenys ASB10 antibody G1QW90 93.0%
ARP69286 Pig ASB10 antibody; Sus scrofa ASB10 antibody I3L6F3 93.0%
ARP69286 Rabbit ASB10 antibody; Oryctolagus cuniculus ASB10 antibody G1TQ03 100.0%
ARP69286 Rat ASB10 antibody; Rattus norvegicus ASB10 antibody B5DEZ7 93.0%
ARP69286 Rhesus macaque ASB10 antibody; Macaca mulatta ASB10 antibody F7GYZ2 100.0%
ARP69286 Rhesus macaque ASB10 antibody; Macaca mulatta ASB10 antibody F7H3X0 100.0%
ARP69286 Small-eared galago ASB10 antibody; Otolemur garnettii ASB10 antibody H0XH32 100.0%
ARP69286 Tasmanian devil ASB10 antibody; Sarcophilus harrisii ASB10 antibody G3WAP8 92.0%
ARP69286 Tasmanian devil ASB10 antibody; Sarcophilus harrisii ASB10 antibody G3WAP9 92.0%
ARP69286 Thirteen-lined ground squirrel ASB10 antibody; Spermophilus tridecemlineatus ASB10 antibody I3MZ15 93.0%
ARP69286 White-tufted-ear marmoset ASB10 antibody; Callithrix jacchus ASB10 antibody F6ZD23 100.0%
ARP69286 White-tufted-ear marmoset ASB10 antibody; Callithrix jacchus ASB10 antibody F6ZD30 100.0%
ARP69286 White-tufted-ear marmoset ASB10 antibody; Callithrix jacchus ASB10 antibody F7FQH9 100.0%
ARP69286 White-tufted-ear marmoset ASB10 antibody; Callithrix jacchus ASB10 antibody U3FDP1 100.0%
ARP69286 White-tufted-ear marmoset ASB10 antibody; Callithrix jacchus ASB10 antibody U3FHY8 100.0%

Tissue & Cell Line Gene Expression Data