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Gene ID: 411 | Arsb Antibody Resource


Arsb Antibody Resource
Gene Full Name: 
arylsulfatase B
Uniprot: 
P15848
Protein Name: 
arylsulfatase B
Nucleotide: 
NM_000046
Alias: 
ASB;G4S;MPS6;
Ensembl: 
ENSG00000113273
Location: 
5q14.1
HPRD: 
08358
NCBI Gene: 
411
MIM: 
611542

Summary: 
Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function: 
Subcellular location: 
Lysosome.
PTM: 
Disulfide bond;
Disease: 
Mucopolysaccharidosis 6 (MPS6) [MIM:253200]: An autosomal recessive lysosomal storage disease characterized by intracellular accumulation of dermatan sulfate. Clinical features can include abnormal growth, short stature, stiff joints, skeletal malformations, corneal clouding, hepatosplenomegaly, and cardiac abnormalities. A wide variation in clinical severity is observed. Note: The disease is caused by mutations affecting the gene represented in this entry. Multiple sulfatase deficiency (MSD) [MIM:272200]: A clinically and biochemically heterogeneous disorder caused by the simultaneous impairment of all sulfatases, due to defective post-translational modification and activation. It combines features of individual sulfatase deficiencies such as metachromatic leukodystrophy, mucopolysaccharidosis, chondrodysplasia punctata, hydrocephalus, ichthyosis, neurologic deterioration and developmental delay. Note: The protein represented in this entry is involved in disease pathogenesis. Arylsulfatase B activity is impaired in multiple sulfatase deficiency due to mutations in SUMF1. SUMF1 mutations result in defective post-translational modification of ARSB at residue Cys-91 that is not converted to 3-oxoalanine.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP58861_P050 Arsb antibody - middle region (ARP58861_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rat WB 50ug $289 Details
Polyclonal Antibody OAEB02462 ARSB Antibody (OAEB02462) Human WB, IHC 0.1mg $289 Details
Polyclonal Antibody OAAB04502 ARSB antibody - C-terminal region (OAAB04502) Human WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody OAAB04503 ARSB antibody - center region (OAAB04503) Human WB, ELISA 400ul $289 Details
Polyclonal Antibody OAAF03306 ARSB Antibody (OAAF03306) Polyclonal Human, Mouse, Rat WB, ELISA 100 ug $229 Details

Show all Arsb antibodies


Product Images
Arsb antibody - middle region (ARP58861_P050) in Mouse Kidney cells using Western Blot

Sample Type: Mouse Kidney

ARSB antibody - C-terminal region (OAAB04502) in HepG2 cells using Western Blot

Sample Type: HepG2

ARSB antibody - C-terminal region (OAAB04502) in human lung carcinoma cells using Immunohistochemistry

Sample Type: human lung carcinoma

ARSB antibody - center region (OAAB04503) in ARSB cells using Western Blot

Sample Type: ARSB

ARSB antibody - center region (OAAB04503) in HL-60 cells using Western Blot

Sample Type: HL-60

ARSB Antibody (OAAF03306) in COLO, HepG2 cells using Western Blot

Sample Type: COLO, HepG2

ARSB Antibody (OAEB02462) in Human Heart cells using Western Blot

Sample Type: Human Heart

ARSB Antibody (OAEB02462) in Humankeletal Muscle cells using Immunohistochemistry

Sample Type: Humankeletal Muscle


Arsb Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP44255 Brevibacillus laterosporus GI-9 Arsb antibody H0U6R9 86.0%
ARP44255 Brevibacillus laterosporus GI-9 Arsb antibody H0UBZ0 86.0%
ARP58861 African elephant Arsb antibody; Loxodonta africana Arsb antibody G3TK20 100.0%
ARP58861 Bovine Arsb antibody; Bos taurus Arsb antibody A6QLZ3 86.0%
ARP58861 Cat Arsb antibody; Felis catus Arsb antibody M3X599 100.0%
ARP58861 Cat Arsb antibody; Felis catus Arsb antibody P33727 100.0%
ARP58861 Chicken Arsb antibody; Gallus gallus Arsb antibody F1P099 79.0%
ARP58861 Chimpanzee Arsb antibody; Pan troglodytes Arsb antibody K7B3C4 100.0%
ARP58861 Chimpanzee Arsb antibody; Pan troglodytes Arsb antibody K7BVK1 100.0%
ARP58861 Chimpanzee Arsb antibody; Pan troglodytes Arsb antibody K7CKP9 100.0%
ARP58861 Chimpanzee Arsb antibody; Pan troglodytes Arsb antibody H2RB02 93.0%
ARP58861 Chimpanzee Arsb antibody; Pan troglodytes Arsb antibody K7BDB6 93.0%
ARP58861 Chimpanzee Arsb antibody; Pan troglodytes Arsb antibody K7DJ89 93.0%
ARP58861 Chinese softshell turtle Arsb antibody; Pelodiscus sinensis Arsb antibody K7FEW5 79.0%
ARP58861 Dog Arsb antibody; Canis familiaris Arsb antibody Q32KI4 86.0%
ARP58861 Duckbill platypus Arsb antibody; Ornithorhynchus anatinus Arsb antibody F7DRZ2 100.0%
ARP58861 European domestic ferret Arsb antibody; Mustela putorius furo Arsb antibody M3Y161 93.0%
ARP58861 Giant panda Arsb antibody; Ailuropoda melanoleuca Arsb antibody D2HE51 100.0%
ARP58861 Horse Arsb antibody; Equus caballus Arsb antibody F6TYS7 100.0%
ARP58861 Human Arsb antibody; Homo sapiens Arsb antibody P15848-2 100.0%
ARP58861 Human Arsb antibody; Homo sapiens Arsb antibody P15848 100.0%
ARP58861 Mouse Arsb antibody; Mus musculus Arsb antibody B2RWQ7 93.0%
ARP58861 Mouse Arsb antibody; Mus musculus Arsb antibody P50429-2 93.0%
ARP58861 Mouse Arsb antibody; Mus musculus Arsb antibody P50429 93.0%
ARP58861 Northern white-cheeked gibbon Arsb antibody; Nomascus leucogenys Arsb antibody G1RQM3 100.0%
ARP44255 Picoplanktonic green alga Arsb antibody; Micromonas pusilla Arsb antibody C1MQZ0 86.0%
ARP58861 Rat Arsb antibody; Rattus norvegicus Arsb antibody A0JPJ3 93.0%
ARP58861 Rat Arsb antibody; Rattus norvegicus Arsb antibody B4F7E2 93.0%
ARP58861 Rat Arsb antibody; Rattus norvegicus Arsb antibody P50430 93.0%
ARP58861 Rhesus macaque Arsb antibody; Macaca mulatta Arsb antibody F7H1H1 100.0%
ARP58861 Rhesus macaque Arsb antibody; Macaca mulatta Arsb antibody F7H1H5 100.0%
ARP58861 Rhesus macaque Arsb antibody; Macaca mulatta Arsb antibody H9F589 100.0%
ARP58861 Small-eared galago Arsb antibody; Otolemur garnettii Arsb antibody H0WYV1 100.0%
ARP58861 Sumatran orangutan Arsb antibody; Pongo abelii Arsb antibody H2PFY4 100.0%
ARP58861 Thirteen-lined ground squirrel Arsb antibody; Spermophilus tridecemlineatus Arsb antibody I3M6Q3 100.0%
ARP58861 West Indian ocean coelacanth Arsb antibody; Latimeria chalumnae Arsb antibody H3BDI4 86.0%
ARP58861 White-tufted-ear marmoset Arsb antibody; Callithrix jacchus Arsb antibody F6Q9K2 100.0%
ARP58861 White-tufted-ear marmoset Arsb antibody; Callithrix jacchus Arsb antibody F6QJ35 100.0%
ARP58861 White-tufted-ear marmoset Arsb antibody; Callithrix jacchus Arsb antibody U3BP00 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas206129_s_at721_B_lymphoblasts4.2503.410Details
BioGPS Gene Atlas206129_s_atAdipocyte3.3503.410Details
BioGPS Gene Atlas206129_s_atAdrenalCortex3.4503.410Details
BioGPS Gene Atlas206129_s_atAdrenalgland2.8503.410Details
BioGPS Gene Atlas206129_s_atAmygdala3.6003.410Details
BioGPS Gene Atlas206129_s_atAppendix3.3503.410Details
BioGPS Gene Atlas206129_s_atAtrioventricularNode2.5503.410Details
BioGPS Gene Atlas206129_s_atBDCA4+_DentriticCells3.8003.410Details
BioGPS Gene Atlas206129_s_atBonemarrow3.3003.410Details
BioGPS Gene Atlas206129_s_atBronchialEpithelialCells3.3503.410Details
BioGPS Gene Atlas206129_s_atCD105+_Endothelial3.4503.410Details
BioGPS Gene Atlas206129_s_atCD14+_Monocytes3.6003.410Details
BioGPS Gene Atlas206129_s_atCD19+_BCells(neg._sel.)3.6003.410Details
BioGPS Gene Atlas206129_s_atCD33+_Myeloid4.4503.410Details
BioGPS Gene Atlas206129_s_atCD34+4.3503.410Details
BioGPS Gene Atlas206129_s_atCD4+_Tcells3.7003.410Details
BioGPS Gene Atlas206129_s_atCD56+_NKCells4.0503.410Details
BioGPS Gene Atlas206129_s_atCD71+_EarlyErythroid3.1503.410Details
BioGPS Gene Atlas206129_s_atCD8+_Tcells3.3003.410Details
BioGPS Gene Atlas206129_s_atCardiacMyocytes4.3503.410Details
BioGPS Gene Atlas206129_s_atCaudatenucleus3.0503.410Details
BioGPS Gene Atlas206129_s_atCerebellum2.7003.410Details
BioGPS Gene Atlas206129_s_atCerebellumPeduncles3.8003.410Details
BioGPS Gene Atlas206129_s_atCiliaryGanglion2.3503.410Details
BioGPS Gene Atlas206129_s_atCingulateCortex3.4003.410Details
BioGPS Gene Atlas206129_s_atColorectaladenocarcinoma3.4003.410Details
BioGPS Gene Atlas206129_s_atDorsalRootGanglion2.5503.410Details
BioGPS Gene Atlas206129_s_atFetalThyroid3.2503.410Details
BioGPS Gene Atlas206129_s_atFetalbrain3.3503.410Details
BioGPS Gene Atlas206129_s_atFetalliver2.9503.410Details
BioGPS Gene Atlas206129_s_atFetallung2.8003.410Details
BioGPS Gene Atlas206129_s_atGlobusPallidus2.5003.410Details
BioGPS Gene Atlas206129_s_atHeart4.3503.410Details
BioGPS Gene Atlas206129_s_atHypothalamus3.7003.410Details
BioGPS Gene Atlas206129_s_atKidney2.7503.410Details
BioGPS Gene Atlas206129_s_atLeukemia_chronicMyelogenousK-5623.0503.410Details
BioGPS Gene Atlas206129_s_atLeukemia_promyelocytic-HL-603.0003.410Details
BioGPS Gene Atlas206129_s_atLeukemialymphoblastic(MOLT-4)2.7003.410Details
BioGPS Gene Atlas206129_s_atLiver4.4503.410Details
BioGPS Gene Atlas206129_s_atLung3.7003.410Details
BioGPS Gene Atlas206129_s_atLymphnode2.9003.410Details
BioGPS Gene Atlas206129_s_atLymphoma_burkitts(Daudi)4.3003.410Details
BioGPS Gene Atlas206129_s_atLymphoma_burkitts(Raji)4.7003.410Details
BioGPS Gene Atlas206129_s_atMedullaOblongata3.1003.410Details
BioGPS Gene Atlas206129_s_atOccipitalLobe3.0003.410Details
BioGPS Gene Atlas206129_s_atOlfactoryBulb2.6503.410Details
BioGPS Gene Atlas206129_s_atOvary2.2003.410Details
BioGPS Gene Atlas206129_s_atPancreas2.7003.410Details
BioGPS Gene Atlas206129_s_atPancreaticIslet3.6003.410Details
BioGPS Gene Atlas206129_s_atParietalLobe3.5503.410Details
BioGPS Gene Atlas206129_s_atPituitary3.9003.410Details
BioGPS Gene Atlas206129_s_atPlacenta3.5003.410Details
BioGPS Gene Atlas206129_s_atPons3.2003.410Details
BioGPS Gene Atlas206129_s_atPrefrontalCortex4.1503.410Details
BioGPS Gene Atlas206129_s_atProstate3.9503.410Details
BioGPS Gene Atlas206129_s_atSalivarygland2.7003.410Details
BioGPS Gene Atlas206129_s_atSkeletalMuscle3.9003.410Details
BioGPS Gene Atlas206129_s_atSkin2.5503.410Details
BioGPS Gene Atlas206129_s_atSmoothMuscle3.8003.410Details
BioGPS Gene Atlas206129_s_atSpinalcord3.5503.410Details
BioGPS Gene Atlas206129_s_atSubthalamicNucleus3.0503.410Details
BioGPS Gene Atlas206129_s_atSuperiorCervicalGanglion3.8003.410Details
BioGPS Gene Atlas206129_s_atTemporalLobe3.1003.410Details
BioGPS Gene Atlas206129_s_atTestis2.9003.410Details
BioGPS Gene Atlas206129_s_atTestisGermCell2.8003.410Details
BioGPS Gene Atlas206129_s_atTestisIntersitial2.8003.410Details
BioGPS Gene Atlas206129_s_atTestisLeydigCell3.3503.410Details
BioGPS Gene Atlas206129_s_atTestisSeminiferousTubule2.9003.410Details
BioGPS Gene Atlas206129_s_atThalamus3.4503.410Details
BioGPS Gene Atlas206129_s_atThymus2.6503.410Details
BioGPS Gene Atlas206129_s_atThyroid4.2503.410Details
BioGPS Gene Atlas206129_s_atTongue3.4003.410Details
BioGPS Gene Atlas206129_s_atTonsil3.2503.410Details
BioGPS Gene Atlas206129_s_atTrachea2.8003.410Details
BioGPS Gene Atlas206129_s_atTrigeminalGanglion3.4503.410Details
BioGPS Gene Atlas206129_s_atUterus2.8003.410Details
BioGPS Gene Atlas206129_s_atUterusCorpus3.0003.410Details
BioGPS Gene Atlas206129_s_atWholeBlood3.7503.410Details
BioGPS Gene Atlas206129_s_atWholebrain2.9003.410Details
BioGPS Gene Atlas206129_s_atcolon3.4003.410Details
BioGPS Gene Atlas206129_s_atpineal_day4.2203.410Details
BioGPS Gene Atlas206129_s_atpineal_night4.1403.410Details
BioGPS Gene Atlas206129_s_atretina4.1003.410Details
BioGPS Gene Atlas206129_s_atsmall_intestine3.2503.410Details
BioGPS NCI60206129_s_at7863.6403.630Details
BioGPS NCI60206129_s_atA1723.5783.630Details
BioGPS NCI60206129_s_atA2043.5743.630Details
BioGPS NCI60206129_s_atA3613.6323.630Details
BioGPS NCI60206129_s_atA4983.5963.630Details
BioGPS NCI60206129_s_atA5493.6473.630Details
BioGPS NCI60206129_s_atACC33.6973.630Details
BioGPS NCI60206129_s_atACHN3.5413.630Details
BioGPS NCI60206129_s_atALVA313.6803.630Details
BioGPS NCI60206129_s_atCAKI13.8083.630Details
BioGPS NCI60206129_s_atCCRT CEM3.7773.630Details
BioGPS NCI60206129_s_atCOLO2053.6033.630Details
BioGPS NCI60206129_s_atDLD13.5773.630Details
BioGPS NCI60206129_s_atDU1453.4873.630Details
BioGPS NCI60206129_s_atEKVX3.5263.630Details
BioGPS NCI60206129_s_atGM1333.7013.630Details
BioGPS NCI60206129_s_atGM16003.7593.630Details
BioGPS NCI60206129_s_atGM23133.6693.630Details
BioGPS NCI60206129_s_atGM23453.6273.630Details
BioGPS NCI60206129_s_atGM24933.7693.630Details
BioGPS NCI60206129_s_atGM974.1563.630Details
BioGPS NCI60206129_s_atHCC29983.3523.630Details
BioGPS NCI60206129_s_atHCT1163.5893.630Details
BioGPS NCI60206129_s_atHCT153.4533.630Details
BioGPS NCI60206129_s_atHEK 293 T-rex3.7123.630Details
BioGPS NCI60206129_s_atHEK 293T3.6393.630Details
BioGPS NCI60206129_s_atHEK2933.6303.630Details
BioGPS NCI60206129_s_atHELA3.4743.630Details
BioGPS NCI60206129_s_atHEPG23.6073.630Details
BioGPS NCI60206129_s_atHL603.6183.630Details
BioGPS NCI60206129_s_atHOP623.6083.630Details
BioGPS NCI60206129_s_atHOP923.5033.630Details
BioGPS NCI60206129_s_atHS578T3.5883.630Details
BioGPS NCI60206129_s_atHSG3.5273.630Details
BioGPS NCI60206129_s_atHT10803.5923.630Details
BioGPS NCI60206129_s_atHT293.7253.630Details
BioGPS NCI60206129_s_atIGROV13.5403.630Details
BioGPS NCI60206129_s_atIOSE803.5873.630Details
BioGPS NCI60206129_s_atJURKAT3.6013.630Details
BioGPS NCI60206129_s_atK5623.7043.630Details
BioGPS NCI60206129_s_atKM123.6713.630Details
BioGPS NCI60206129_s_atLN183.7003.630Details
BioGPS NCI60206129_s_atLNCAP3.6003.630Details
BioGPS NCI60206129_s_atLOX IMVI3.6013.630Details
BioGPS NCI60206129_s_atM143.5893.630Details
BioGPS NCI60206129_s_atMALME 3M3.7053.630Details
BioGPS NCI60206129_s_atMCF73.4653.630Details
BioGPS NCI60206129_s_atMD MB2313.6003.630Details
BioGPS NCI60206129_s_atMDA MB4353.7443.630Details
BioGPS NCI60206129_s_atMOLT43.6163.630Details
BioGPS NCI60206129_s_atNCI 4603.6893.630Details
BioGPS NCI60206129_s_atNCI H2263.6483.630Details
BioGPS NCI60206129_s_atNCI H233.5983.630Details
BioGPS NCI60206129_s_atNCI H322M3.6143.630Details
BioGPS NCI60206129_s_atNCVADR RES3.3503.630Details
BioGPS NCI60206129_s_atOVCAR33.6883.630Details
BioGPS NCI60206129_s_atOVCAR43.5903.630Details
BioGPS NCI60206129_s_atOVCAR53.5233.630Details
BioGPS NCI60206129_s_atOVCAR83.4803.630Details
BioGPS NCI60206129_s_atPANC13.6093.630Details
BioGPS NCI60206129_s_atRL73.6813.630Details
BioGPS NCI60206129_s_atRPMI 82263.6473.630Details
BioGPS NCI60206129_s_atRS118463.6763.630Details
BioGPS NCI60206129_s_atRXF3933.5993.630Details
BioGPS NCI60206129_s_atSAOS23.6343.630Details
BioGPS NCI60206129_s_atSF2683.5983.630Details
BioGPS NCI60206129_s_atSF2953.5353.630Details
BioGPS NCI60206129_s_atSF5393.4253.630Details
BioGPS NCI60206129_s_atSHSYSY+RA3.5293.630Details
BioGPS NCI60206129_s_atSHSYSY-RA3.5313.630Details
BioGPS NCI60206129_s_atSKMEL23.5983.630Details
BioGPS NCI60206129_s_atSKMEL283.6083.630Details
BioGPS NCI60206129_s_atSKMEL53.5463.630Details
BioGPS NCI60206129_s_atSKOV33.6773.630Details
BioGPS NCI60206129_s_atSN12C3.6753.630Details
BioGPS NCI60206129_s_atSNB193.5183.630Details
BioGPS NCI60206129_s_atSNB753.5973.630Details
BioGPS NCI60206129_s_atSR3.6393.630Details
BioGPS NCI60206129_s_atSW6203.6283.630Details
BioGPS NCI60206129_s_atT243.6703.630Details
BioGPS NCI60206129_s_atT3M43.6433.630Details
BioGPS NCI60206129_s_atTK103.5793.630Details
BioGPS NCI60206129_s_atU1183.6033.630Details
BioGPS NCI60206129_s_atU1384.0023.630Details
BioGPS NCI60206129_s_atU20S3.6153.630Details
BioGPS NCI60206129_s_atU2513.5223.630Details
BioGPS NCI60206129_s_atU873.5793.630Details
BioGPS NCI60206129_s_atUACC2573.5723.630Details
BioGPS NCI60206129_s_atUACC623.9993.630Details
BioGPS NCI60206129_s_atUO313.4903.630Details
BioGPS NCI60206129_s_atZR75_13.6763.630Details
BioGPS NCI60206129_s_atastrocytes3.6423.630Details
BioGPS NCI60206129_s_athuh-73.7463.630Details