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Gene ID: 9459 | ARHGEF6 Antibody Resource


ARHGEF6 Antibody Resource
Gene Full Name: 
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
Uniprot: 
Q15052
Protein Name: 
rho guanine nucleotide exchange factor 6
Nucleotide: 
XM_005262499
Alias: 
PIXA;COOL2;MRX46;Cool-2;alphaPIX;alpha-PIX;
Ensembl: 
ENSG00000129675
Location: 
Xq26.3
HPRD: 
02226
NCBI Gene: 
9459
MIM: 
300267

Summary: 
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq, Jul 2008]
Function: 
Acts as a RAC1 guanine nucleotide exchange factor (GEF).
Subcellular location: 
Cell projection › lamellipodium.
PTM: 
Phosphoprotein;
Disease: 
Mental retardation, X-linked 46 (MRX46) [MIM:300436]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation, while syndromic mental retardation presents with associated physical, neurological and/or psychiatric manifestations. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP61924_P050 ARHGEF6 Antibody (ARP61924_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB12154 ARHGEF6 antibody - C - terminal region (OAAB12154) Human WB 400ul $289 Details

Show all ARHGEF6 antibodies


Product Images
ARHGEF6 antibody - C - terminal region (OAAB12154) in K562 cells using Western Blot

Sample Type: K562


ARHGEF6 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP61924 African elephant ARHGEF6 antibody; Loxodonta africana ARHGEF6 antibody G3SWH3 100.0%
ARP61924 African elephant ARHGEF6 antibody; Loxodonta africana ARHGEF6 antibody G3UGF4 100.0%
ARP61924 African elephant ARHGEF6 antibody; Loxodonta africana ARHGEF6 antibody G3UDP7 81.0%
ARP61924 Bovine ARHGEF6 antibody; Bos taurus ARHGEF6 antibody E1BIM5 100.0%
ARP61924 Cat ARHGEF6 antibody; Felis catus ARHGEF6 antibody M3W1P8 100.0%
ARP59644 Chicken ARHGEF6 antibody; Gallus gallus ARHGEF6 antibody Q5ZLR6 85.0%
ARP61924 Chicken ARHGEF6 antibody; Gallus gallus ARHGEF6 antibody Q5ZLR6 85.0%
ARP59644 Chicken ARHGEF6 antibody; Gallus gallus ARHGEF6 antibody F1NEF5 85.0%
ARP61924 Chicken ARHGEF6 antibody; Gallus gallus ARHGEF6 antibody F1NEF5 85.0%
ARP61924 Chimpanzee ARHGEF6 antibody; Pan troglodytes ARHGEF6 antibody H2R1Z7 100.0%
ARP61924 Chimpanzee ARHGEF6 antibody; Pan troglodytes ARHGEF6 antibody K6ZX72 100.0%
ARP59644 Chinese softshell turtle ARHGEF6 antibody; Pelodiscus sinensis ARHGEF6 antibody K7FVG7 92.0%
ARP61924 Chinese softshell turtle ARHGEF6 antibody; Pelodiscus sinensis ARHGEF6 antibody K7FVG7 92.0%
ARP59644 Collared flycatcher ARHGEF6 antibody; Ficedula albicollis ARHGEF6 antibody U3JMA9 92.0%
ARP61924 Collared flycatcher ARHGEF6 antibody; Ficedula albicollis ARHGEF6 antibody U3JMA9 85.0%
ARP61924 Dog ARHGEF6 antibody; Canis familiaris ARHGEF6 antibody E2R0Z1 100.0%
ARP59644 Domestic duck ARHGEF6 antibody; Anas platyrhynchos ARHGEF6 antibody R0JLG7 85.0%
ARP61924 European domestic ferret ARHGEF6 antibody; Mustela putorius furo ARHGEF6 antibody M3XS19 100.0%
ARP61924 Gray short-tailed opossum ARHGEF6 antibody; Monodelphis domestica ARHGEF6 antibody F6TST1 86.0%
ARP61924 Horse ARHGEF6 antibody; Equus caballus ARHGEF6 antibody F6REK1 100.0%
ARP61924 Human ARHGEF6 antibody; Homo sapiens ARHGEF6 antibody Q15052 100.0%
ARP61924 Mouse ARHGEF6 antibody; Mus musculus ARHGEF6 antibody Q8K4I3 100.0%
ARP61924 Mouse ARHGEF6 antibody; Mus musculus ARHGEF6 antibody F6WMJ3 100.0%
ARP61924 Northern white-cheeked gibbon ARHGEF6 antibody; Nomascus leucogenys ARHGEF6 antibody G1QRL8 100.0%
ARP61924 Pig ARHGEF6 antibody; Sus scrofa ARHGEF6 antibody I3LMB2 100.0%
ARP61924 Rabbit ARHGEF6 antibody; Oryctolagus cuniculus ARHGEF6 antibody G1SCX4 100.0%
ARP61924 Rat ARHGEF6 antibody; Rattus norvegicus ARHGEF6 antibody Q5XXR3 100.0%
ARP61924 Rat ARHGEF6 antibody; Rattus norvegicus ARHGEF6 antibody D3ZWQ8 100.0%
ARP61924 Rhesus macaque ARHGEF6 antibody; Macaca mulatta ARHGEF6 antibody F6Q0Q9 100.0%
ARP61924 Rhesus macaque ARHGEF6 antibody; Macaca mulatta ARHGEF6 antibody G7NRP9 100.0%
ARP59644 Spotted green pufferfish ARHGEF6 antibody; Tetraodon nigroviridis ARHGEF6 antibody H3DHG4 83.0%
ARP61924 Sumatran orangutan ARHGEF6 antibody; Pongo abelii ARHGEF6 antibody H2PWX9 100.0%
ARP59644 Western clawed frog ARHGEF6 antibody; Xenopus tropicalis ARHGEF6 antibody F7BWF4 83.0%
ARP61924 White-tufted-ear marmoset ARHGEF6 antibody; Callithrix jacchus ARHGEF6 antibody F6UQP9 100.0%
ARP59644 White-tufted-ear marmoset ARHGEF6 antibody; Callithrix jacchus ARHGEF6 antibody F6UQP9 79.0%
ARP59644 White-tufted-ear marmoset ARHGEF6 antibody; Callithrix jacchus ARHGEF6 antibody F6VB40 79.0%
ARP59644 White-tufted-ear marmoset ARHGEF6 antibody; Callithrix jacchus ARHGEF6 antibody F7H5V7 79.0%
ARP59644 White-tufted-ear marmoset ARHGEF6 antibody; Callithrix jacchus ARHGEF6 antibody F7H5X3 79.0%
ARP59644 Zebra finch ARHGEF6 antibody; Taeniopygia guttata ARHGEF6 antibody H0YV78 92.0%
ARP59644 Zebrafish ARHGEF6 antibody; Danio rerio ARHGEF6 antibody E7F836 85.0%
ARP59644 Zebrafish ARHGEF6 antibody; Danio rerio ARHGEF6 antibody F8W5F0 85.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas209539_at721_B_lymphoblasts14.700102.010Details
BioGPS Gene Atlas209539_atAdipocyte28.750102.010Details
BioGPS Gene Atlas209539_atAdrenalCortex31.000102.010Details
BioGPS Gene Atlas209539_atAdrenalgland31.900102.010Details
BioGPS Gene Atlas209539_atAmygdala80.200102.010Details
BioGPS Gene Atlas209539_atAppendix29.250102.010Details
BioGPS Gene Atlas209539_atAtrioventricularNode19.050102.010Details
BioGPS Gene Atlas209539_atBDCA4+_DentriticCells568.850102.010Details
BioGPS Gene Atlas209539_atBonemarrow39.200102.010Details
BioGPS Gene Atlas209539_atBronchialEpithelialCells14.050102.010Details
BioGPS Gene Atlas209539_atCD105+_Endothelial31.300102.010Details
BioGPS Gene Atlas209539_atCD14+_Monocytes597.950102.010Details
BioGPS Gene Atlas209539_atCD19+_BCells(neg._sel.)315.800102.010Details
BioGPS Gene Atlas209539_atCD33+_Myeloid720.500102.010Details
BioGPS Gene Atlas209539_atCD34+785.650102.010Details
BioGPS Gene Atlas209539_atCD4+_Tcells1053.200102.010Details
BioGPS Gene Atlas209539_atCD56+_NKCells690.150102.010Details
BioGPS Gene Atlas209539_atCD71+_EarlyErythroid12.200102.010Details
BioGPS Gene Atlas209539_atCD8+_Tcells790.550102.010Details
BioGPS Gene Atlas209539_atCardiacMyocytes38.700102.010Details
BioGPS Gene Atlas209539_atCaudatenucleus33.500102.010Details
BioGPS Gene Atlas209539_atCerebellum25.750102.010Details
BioGPS Gene Atlas209539_atCerebellumPeduncles23.250102.010Details
BioGPS Gene Atlas209539_atCiliaryGanglion19.000102.010Details
BioGPS Gene Atlas209539_atCingulateCortex28.150102.010Details
BioGPS Gene Atlas209539_atColorectaladenocarcinoma23.850102.010Details
BioGPS Gene Atlas209539_atDorsalRootGanglion22.200102.010Details
BioGPS Gene Atlas209539_atFetalThyroid31.050102.010Details
BioGPS Gene Atlas209539_atFetalbrain45.950102.010Details
BioGPS Gene Atlas209539_atFetalliver27.850102.010Details
BioGPS Gene Atlas209539_atFetallung23.300102.010Details
BioGPS Gene Atlas209539_atGlobusPallidus14.600102.010Details
BioGPS Gene Atlas209539_atHeart36.400102.010Details
BioGPS Gene Atlas209539_atHypothalamus105.000102.010Details
BioGPS Gene Atlas209539_atKidney23.850102.010Details
BioGPS Gene Atlas209539_atLeukemia_chronicMyelogenousK-56230.650102.010Details
BioGPS Gene Atlas209539_atLeukemia_promyelocytic-HL-6037.100102.010Details
BioGPS Gene Atlas209539_atLeukemialymphoblastic(MOLT-4)179.650102.010Details
BioGPS Gene Atlas209539_atLiver38.150102.010Details
BioGPS Gene Atlas209539_atLung33.000102.010Details
BioGPS Gene Atlas209539_atLymphnode134.150102.010Details
BioGPS Gene Atlas209539_atLymphoma_burkitts(Daudi)36.600102.010Details
BioGPS Gene Atlas209539_atLymphoma_burkitts(Raji)83.850102.010Details
BioGPS Gene Atlas209539_atMedullaOblongata29.050102.010Details
BioGPS Gene Atlas209539_atOccipitalLobe31.700102.010Details
BioGPS Gene Atlas209539_atOlfactoryBulb44.200102.010Details
BioGPS Gene Atlas209539_atOvary19.200102.010Details
BioGPS Gene Atlas209539_atPancreas24.100102.010Details
BioGPS Gene Atlas209539_atPancreaticIslet48.600102.010Details
BioGPS Gene Atlas209539_atParietalLobe36.650102.010Details
BioGPS Gene Atlas209539_atPituitary35.700102.010Details
BioGPS Gene Atlas209539_atPlacenta28.650102.010Details
BioGPS Gene Atlas209539_atPons30.900102.010Details
BioGPS Gene Atlas209539_atPrefrontalCortex42.500102.010Details
BioGPS Gene Atlas209539_atProstate30.350102.010Details
BioGPS Gene Atlas209539_atSalivarygland22.600102.010Details
BioGPS Gene Atlas209539_atSkeletalMuscle43.300102.010Details
BioGPS Gene Atlas209539_atSkin17.300102.010Details
BioGPS Gene Atlas209539_atSmoothMuscle31.100102.010Details
BioGPS Gene Atlas209539_atSpinalcord191.950102.010Details
BioGPS Gene Atlas209539_atSubthalamicNucleus19.400102.010Details
BioGPS Gene Atlas209539_atSuperiorCervicalGanglion27.950102.010Details
BioGPS Gene Atlas209539_atTemporalLobe19.400102.010Details
BioGPS Gene Atlas209539_atTestis24.250102.010Details
BioGPS Gene Atlas209539_atTestisGermCell18.500102.010Details
BioGPS Gene Atlas209539_atTestisIntersitial16.500102.010Details
BioGPS Gene Atlas209539_atTestisLeydigCell21.500102.010Details
BioGPS Gene Atlas209539_atTestisSeminiferousTubule19.450102.010Details
BioGPS Gene Atlas209539_atThalamus37.150102.010Details
BioGPS Gene Atlas209539_atThymus46.850102.010Details
BioGPS Gene Atlas209539_atThyroid43.050102.010Details
BioGPS Gene Atlas209539_atTongue28.300102.010Details
BioGPS Gene Atlas209539_atTonsil81.300102.010Details
BioGPS Gene Atlas209539_atTrachea24.450102.010Details
BioGPS Gene Atlas209539_atTrigeminalGanglion24.650102.010Details
BioGPS Gene Atlas209539_atUterus56.900102.010Details
BioGPS Gene Atlas209539_atUterusCorpus25.800102.010Details
BioGPS Gene Atlas209539_atWholeBlood254.800102.010Details
BioGPS Gene Atlas209539_atWholebrain26.800102.010Details
BioGPS Gene Atlas209539_atcolon32.950102.010Details
BioGPS Gene Atlas209539_atpineal_day54.060102.010Details
BioGPS Gene Atlas209539_atpineal_night82.980102.010Details
BioGPS Gene Atlas209539_atretina48.875102.010Details
BioGPS Gene Atlas209539_atsmall_intestine28.850102.010Details
BioGPS NCI60209539_at78647.74971.040Details
BioGPS NCI60209539_atA17234.41071.040Details
BioGPS NCI60209539_atA204149.66371.040Details
BioGPS NCI60209539_atA36114.97971.040Details
BioGPS NCI60209539_atA498169.37071.040Details
BioGPS NCI60209539_atA54915.09671.040Details
BioGPS NCI60209539_atACC315.85671.040Details
BioGPS NCI60209539_atACHN19.60771.040Details
BioGPS NCI60209539_atALVA3119.77971.040Details
BioGPS NCI60209539_atCAKI119.84971.040Details
BioGPS NCI60209539_atCCRT CEM115.42971.040Details
BioGPS NCI60209539_atCOLO20513.76771.040Details
BioGPS NCI60209539_atDLD114.46171.040Details
BioGPS NCI60209539_atDU14510.11571.040Details
BioGPS NCI60209539_atEKVX12.69071.040Details
BioGPS NCI60209539_atGM13353.41571.040Details
BioGPS NCI60209539_atGM1600133.17171.040Details
BioGPS NCI60209539_atGM2313122.61571.040Details
BioGPS NCI60209539_atGM2345369.21071.040Details
BioGPS NCI60209539_atGM2493155.22671.040Details
BioGPS NCI60209539_atGM97108.76171.040Details
BioGPS NCI60209539_atHCC299811.67671.040Details
BioGPS NCI60209539_atHCT11614.79071.040Details
BioGPS NCI60209539_atHCT1514.00371.040Details
BioGPS NCI60209539_atHEK 293 T-rex51.80071.040Details
BioGPS NCI60209539_atHEK 293T34.43271.040Details
BioGPS NCI60209539_atHEK29353.55971.040Details
BioGPS NCI60209539_atHELA10.69671.040Details
BioGPS NCI60209539_atHEPG214.71271.040Details
BioGPS NCI60209539_atHL6083.34371.040Details
BioGPS NCI60209539_atHOP6214.88471.040Details
BioGPS NCI60209539_atHOP9220.87371.040Details
BioGPS NCI60209539_atHS578T15.44271.040Details
BioGPS NCI60209539_atHSG14.51971.040Details
BioGPS NCI60209539_atHT108030.13971.040Details
BioGPS NCI60209539_atHT2912.38771.040Details
BioGPS NCI60209539_atIGROV114.58671.040Details
BioGPS NCI60209539_atIOSE8014.61471.040Details
BioGPS NCI60209539_atJURKAT324.13871.040Details
BioGPS NCI60209539_atK56220.64071.040Details
BioGPS NCI60209539_atKM1216.42071.040Details
BioGPS NCI60209539_atLN1843.73671.040Details
BioGPS NCI60209539_atLNCAP14.76971.040Details
BioGPS NCI60209539_atLOX IMVI19.56671.040Details
BioGPS NCI60209539_atM1496.84371.040Details
BioGPS NCI60209539_atMALME 3M19.98371.040Details
BioGPS NCI60209539_atMCF711.37371.040Details
BioGPS NCI60209539_atMD MB23117.63071.040Details
BioGPS NCI60209539_atMDA MB43525.91071.040Details
BioGPS NCI60209539_atMOLT4713.95371.040Details
BioGPS NCI60209539_atNCI 46015.15471.040Details
BioGPS NCI60209539_atNCI H22615.17471.040Details
BioGPS NCI60209539_atNCI H2315.56271.040Details
BioGPS NCI60209539_atNCI H322M17.00171.040Details
BioGPS NCI60209539_atNCVADR RES14.35771.040Details
BioGPS NCI60209539_atOVCAR315.49071.040Details
BioGPS NCI60209539_atOVCAR414.80971.040Details
BioGPS NCI60209539_atOVCAR514.50471.040Details
BioGPS NCI60209539_atOVCAR812.98171.040Details
BioGPS NCI60209539_atPANC137.27871.040Details
BioGPS NCI60209539_atRL7382.89371.040Details
BioGPS NCI60209539_atRPMI 822614.98771.040Details
BioGPS NCI60209539_atRS11846140.11571.040Details
BioGPS NCI60209539_atRXF39333.26571.040Details
BioGPS NCI60209539_atSAOS2151.56771.040Details
BioGPS NCI60209539_atSF26814.74871.040Details
BioGPS NCI60209539_atSF29565.54271.040Details
BioGPS NCI60209539_atSF53919.23471.040Details
BioGPS NCI60209539_atSHSYSY+RA17.75371.040Details
BioGPS NCI60209539_atSHSYSY-RA38.78271.040Details
BioGPS NCI60209539_atSKMEL219.38071.040Details
BioGPS NCI60209539_atSKMEL2814.80371.040Details
BioGPS NCI60209539_atSKMEL512.63671.040Details
BioGPS NCI60209539_atSKOV315.09271.040Details
BioGPS NCI60209539_atSN12C14.79071.040Details
BioGPS NCI60209539_atSNB1943.26671.040Details
BioGPS NCI60209539_atSNB75409.52471.040Details
BioGPS NCI60209539_atSR340.76871.040Details
BioGPS NCI60209539_atSW62014.94371.040Details
BioGPS NCI60209539_atT2415.17471.040Details
BioGPS NCI60209539_atT3M415.33471.040Details
BioGPS NCI60209539_atTK1014.85071.040Details
BioGPS NCI60209539_atU118173.48371.040Details
BioGPS NCI60209539_atU138112.55871.040Details
BioGPS NCI60209539_atU20S14.28071.040Details
BioGPS NCI60209539_atU25165.24771.040Details
BioGPS NCI60209539_atU87539.30571.040Details
BioGPS NCI60209539_atUACC25713.01471.040Details
BioGPS NCI60209539_atUACC6252.17471.040Details
BioGPS NCI60209539_atUO3112.93271.040Details
BioGPS NCI60209539_atZR75_119.69471.040Details
BioGPS NCI60209539_atastrocytes49.61071.040Details
BioGPS NCI60209539_athuh-717.57171.040Details