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Gene ID: 115557 | ARHGEF25 Antibody Resource


ARHGEF25 Antibody Resource
Gene Full Name: 
Rho guanine nucleotide exchange factor (GEF) 25
Uniprot: 
Q86VW2
Protein Name: 
rho guanine nucleotide exchange factor 25
Nucleotide: 
NM_001111270
Alias: 
GEFT;p63RhoGEF;
Ensembl: 
ENSG00000240771
Location: 
12q13.3
HPRD: 
13573
NCBI Gene: 
115557
MIM: 
610215

Summary: 
Rho GTPases alternate between an inactive GDP-bound state and an active GTP-bound state, and GEFs facilitate GDP/GTP exchange. This gene encodes a guanine nucleotide exchange factor (GEF) which interacts with Rho GTPases involved in contraction of vascular smooth muscles, regulation of responses to angiotensin II and lens cell differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Function: 
May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved in skeletal myogenesis .
Subcellular location: 
Cell membrane. Cytoplasm › myofibril › sarcomere. Note: Highly colocalizes with actin regions.
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP53438_P050 GEFT antibody - C-terminal region (ARP53438_P050) Polyclonal Rat WB 50ug $289 Details
Polyclonal Antibody ARP53437_P050 ARHGEF25 Antibody (ARP53437_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details

Show all ARHGEF25 antibodies


Product Images
GEFT antibody - C-terminal region (ARP53438_P050) in Human Brain cells using Western Blot

Sample Type: Human Brain


ARHGEF25 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP53437 Bovine ARHGEF25 antibody; Bos taurus ARHGEF25 antibody F1MWU7 100.0%
ARP53438 Bovine ARHGEF25 antibody; Bos taurus ARHGEF25 antibody F1MWU7 92.0%
ARP53437 Cat ARHGEF25 antibody; Felis catus ARHGEF25 antibody M3VXV9 100.0%
ARP53437 Chimpanzee ARHGEF25 antibody; Pan troglodytes ARHGEF25 antibody H2QZR2 100.0%
ARP53438 Chimpanzee ARHGEF25 antibody; Pan troglodytes ARHGEF25 antibody H2QZR2 100.0%
ARP53437 Chimpanzee ARHGEF25 antibody; Pan troglodytes ARHGEF25 antibody H2RBT9 100.0%
ARP53438 Chimpanzee ARHGEF25 antibody; Pan troglodytes ARHGEF25 antibody H2RBT9 100.0%
ARP53437 Dog ARHGEF25 antibody; Canis familiaris ARHGEF25 antibody F1PA09 100.0%
ARP53438 Dog ARHGEF25 antibody; Canis familiaris ARHGEF25 antibody F1PA09 85.0%
ARP53437 European domestic ferret ARHGEF25 antibody; Mustela putorius furo ARHGEF25 antibody M3XS57 100.0%
ARP53438 European domestic ferret ARHGEF25 antibody; Mustela putorius furo ARHGEF25 antibody M3XS57 92.0%
ARP53437 Giant panda ARHGEF25 antibody; Ailuropoda melanoleuca ARHGEF25 antibody D2H389 100.0%
ARP53437 Horse ARHGEF25 antibody; Equus caballus ARHGEF25 antibody F6S4V5 100.0%
ARP53438 Horse ARHGEF25 antibody; Equus caballus ARHGEF25 antibody F6S4V5 85.0%
ARP53437 Human ARHGEF25 antibody; Homo sapiens ARHGEF25 antibody Q86VW2-2 100.0%
ARP53438 Human ARHGEF25 antibody; Homo sapiens ARHGEF25 antibody Q86VW2-2 100.0%
ARP53437 Human ARHGEF25 antibody; Homo sapiens ARHGEF25 antibody Q86VW2-3 100.0%
ARP53438 Human ARHGEF25 antibody; Homo sapiens ARHGEF25 antibody Q86VW2-3 100.0%
ARP53437 Human ARHGEF25 antibody; Homo sapiens ARHGEF25 antibody Q86VW2 100.0%
ARP53438 Human ARHGEF25 antibody; Homo sapiens ARHGEF25 antibody Q86VW2 100.0%
ARP53437 Mouse ARHGEF25 antibody; Mus musculus ARHGEF25 antibody Q9CWR0-2 100.0%
ARP53437 Mouse ARHGEF25 antibody; Mus musculus ARHGEF25 antibody Q9CWR0 100.0%
ARP53437 Mouse ARHGEF25 antibody; Mus musculus ARHGEF25 antibody G5E825 100.0%
ARP53438 Mouse ARHGEF25 antibody; Mus musculus ARHGEF25 antibody Q9CWR0-2 85.0%
ARP53438 Mouse ARHGEF25 antibody; Mus musculus ARHGEF25 antibody Q9CWR0 85.0%
ARP53438 Mouse ARHGEF25 antibody; Mus musculus ARHGEF25 antibody G5E825 85.0%
ARP53437 Northern white-cheeked gibbon ARHGEF25 antibody; Nomascus leucogenys ARHGEF25 antibody G1S632 100.0%
ARP53438 Northern white-cheeked gibbon ARHGEF25 antibody; Nomascus leucogenys ARHGEF25 antibody G1S632 100.0%
ARP53437 Rabbit ARHGEF25 antibody; Oryctolagus cuniculus ARHGEF25 antibody G1T6R3 100.0%
ARP53438 Rabbit ARHGEF25 antibody; Oryctolagus cuniculus ARHGEF25 antibody G1T6R3 85.0%
ARP53437 Rat ARHGEF25 antibody; Rattus norvegicus ARHGEF25 antibody Q6P720 100.0%
ARP53438 Rat ARHGEF25 antibody; Rattus norvegicus ARHGEF25 antibody Q6P720 85.0%
ARP53437 Rhesus macaque ARHGEF25 antibody; Macaca mulatta ARHGEF25 antibody I0FP19 100.0%
ARP53438 Rhesus macaque ARHGEF25 antibody; Macaca mulatta ARHGEF25 antibody I0FP19 100.0%
ARP53437 Small-eared galago ARHGEF25 antibody; Otolemur garnettii ARHGEF25 antibody H0Y0F3 100.0%
ARP53438 Small-eared galago ARHGEF25 antibody; Otolemur garnettii ARHGEF25 antibody H0Y0F3 92.0%
ARP53437 Sumatran orangutan ARHGEF25 antibody; Pongo abelii ARHGEF25 antibody H2NHU3 100.0%
ARP53438 Sumatran orangutan ARHGEF25 antibody; Pongo abelii ARHGEF25 antibody H2NHU3 100.0%
ARP53437 Tasmanian devil ARHGEF25 antibody; Sarcophilus harrisii ARHGEF25 antibody G3W203 100.0%
ARP53437 Thirteen-lined ground squirrel ARHGEF25 antibody; Spermophilus tridecemlineatus ARHGEF25 antibody I3LY51 100.0%
ARP53438 Thirteen-lined ground squirrel ARHGEF25 antibody; Spermophilus tridecemlineatus ARHGEF25 antibody I3LY51 92.0%
ARP53437 Western clawed frog ARHGEF25 antibody; Xenopus tropicalis ARHGEF25 antibody B3DLI2 86.0%
ARP53437 White-tufted-ear marmoset ARHGEF25 antibody; Callithrix jacchus ARHGEF25 antibody F6TVN7 100.0%
ARP53437 White-tufted-ear marmoset ARHGEF25 antibody; Callithrix jacchus ARHGEF25 antibody F7EYL1 100.0%
ARP53437 White-tufted-ear marmoset ARHGEF25 antibody; Callithrix jacchus ARHGEF25 antibody F7HL99 100.0%
ARP53437 White-tufted-ear marmoset ARHGEF25 antibody; Callithrix jacchus ARHGEF25 antibody F7IFW8 100.0%
ARP53437 White-tufted-ear marmoset ARHGEF25 antibody; Callithrix jacchus ARHGEF25 antibody U3F4K5 100.0%
ARP53438 White-tufted-ear marmoset ARHGEF25 antibody; Callithrix jacchus ARHGEF25 antibody F6TVN7 92.0%
ARP53438 White-tufted-ear marmoset ARHGEF25 antibody; Callithrix jacchus ARHGEF25 antibody F7EYL1 92.0%
ARP53438 White-tufted-ear marmoset ARHGEF25 antibody; Callithrix jacchus ARHGEF25 antibody F7HL99 92.0%
ARP53438 White-tufted-ear marmoset ARHGEF25 antibody; Callithrix jacchus ARHGEF25 antibody F7IFW8 92.0%
ARP53438 White-tufted-ear marmoset ARHGEF25 antibody; Callithrix jacchus ARHGEF25 antibody U3F4K5 92.0%

Tissue & Cell Line Gene Expression Data