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Gene ID: 23370 | ARHGEF18 Antibody Resource


ARHGEF18 Antibody Resource
Gene Full Name: 
Rho/Rac guanine nucleotide exchange factor (GEF) 18
Uniprot: 
Q6ZSZ5
Protein Name: 
rho guanine nucleotide exchange factor 18
Nucleotide: 
XM_005272463
Alias: 
P114-RhoGEF;
Ensembl: 
ENSG00000104880
Location: 
19p13.3
HPRD: 
12479
NCBI Gene: 
23370
MIM: 

Summary: 
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
Function: 
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. Also act as a GEF for RAC1, inducing production of reactive oxygen species (ROS). Does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production.
Subcellular location: 
Cytoplasm. Note: Colocalizes with actin stress fibers.
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAEB02494 Goat Anti-P114-RHO-GEF / ARHGEF18 Antibody (OAEB02494) Bovine, Dog, Guinea pig, Pig, Rabbit ELISA, WB, IP, ICC, IF 0.1mg $289 Details
Polyclonal Antibody ARP62699_P050 ARHGEF18 Antibody (ARP62699_P050) Polyclonal Bovine, Dog, Human, Mouse, Pig, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP62700_P050 ARHGEF18 Antibody (ARP62700_P050) Polyclonal Bovine, Dog, Guinea pig, Human, Mouse, Pig, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB13341 ARHGEF18 antibody - N - terminal region (OAAB13341) Human WB 400ul $289 Details
Polyclonal Antibody OAGA00171 ARHGEF18 antibody (OAGA00171) Polyclonal Human ICC/IF, WB 100 ul $340 Details

Show all ARHGEF18 antibodies


Product Images
ARHGEF18 antibody - N - terminal region (OAAB13341) in 293 cells using Western Blot

Sample Type: 293


ARHGEF18 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP62700 Bovine ARHGEF18 antibody; Bos taurus ARHGEF18 antibody E1B9G8 93.0%
ARP62700 Bovine ARHGEF18 antibody; Bos taurus ARHGEF18 antibody G3N3B9 93.0%
ARP62699 Bovine ARHGEF18 antibody; Bos taurus ARHGEF18 antibody E1B9G8 86.0%
ARP62699 Bovine ARHGEF18 antibody; Bos taurus ARHGEF18 antibody G3N3B9 86.0%
ARP62699 Chimpanzee ARHGEF18 antibody; Pan troglodytes ARHGEF18 antibody H2R291 100.0%
ARP62700 Chimpanzee ARHGEF18 antibody; Pan troglodytes ARHGEF18 antibody H2R291 100.0%
ARP62700 Dog ARHGEF18 antibody; Canis familiaris ARHGEF18 antibody E2RKN0 100.0%
ARP62700 Dog ARHGEF18 antibody; Canis familiaris ARHGEF18 antibody F1P9G9 100.0%
ARP62699 Dog ARHGEF18 antibody; Canis familiaris ARHGEF18 antibody E2RKN0 86.0%
ARP62699 Dog ARHGEF18 antibody; Canis familiaris ARHGEF18 antibody F1P9G9 86.0%
ARP62700 European domestic ferret ARHGEF18 antibody; Mustela putorius furo ARHGEF18 antibody M3YAI0 100.0%
ARP62699 European domestic ferret ARHGEF18 antibody; Mustela putorius furo ARHGEF18 antibody M3YAI0 85.0%
ARP62699 Gray short-tailed opossum ARHGEF18 antibody; Monodelphis domestica ARHGEF18 antibody F7CZN8 79.0%
ARP62699 Human ARHGEF18 antibody; Homo sapiens ARHGEF18 antibody M0QZS0 100.0%
ARP62700 Human ARHGEF18 antibody; Homo sapiens ARHGEF18 antibody M0QZS0 100.0%
ARP62699 Human ARHGEF18 antibody; Homo sapiens ARHGEF18 antibody M0R150 100.0%
ARP62700 Human ARHGEF18 antibody; Homo sapiens ARHGEF18 antibody M0R150 100.0%
ARP62699 Human ARHGEF18 antibody; Homo sapiens ARHGEF18 antibody Q6ZSZ5-2 100.0%
ARP62700 Human ARHGEF18 antibody; Homo sapiens ARHGEF18 antibody Q6ZSZ5-2 100.0%
ARP62699 Human ARHGEF18 antibody; Homo sapiens ARHGEF18 antibody Q6ZSZ5 100.0%
ARP62700 Human ARHGEF18 antibody; Homo sapiens ARHGEF18 antibody Q6ZSZ5 100.0%
ARP62699 Mouse ARHGEF18 antibody; Mus musculus ARHGEF18 antibody Q6P9R4 92.0%
ARP62700 Mouse ARHGEF18 antibody; Mus musculus ARHGEF18 antibody Q6P9R4-2 86.0%
ARP62700 Mouse ARHGEF18 antibody; Mus musculus ARHGEF18 antibody Q6P9R4 86.0%
ARP62700 Pig ARHGEF18 antibody; Sus scrofa ARHGEF18 antibody F1SCK5 93.0%
ARP62699 Pig ARHGEF18 antibody; Sus scrofa ARHGEF18 antibody F1SCK5 86.0%
ARP62699 Rat ARHGEF18 antibody; Rattus norvegicus ARHGEF18 antibody F1LT94 86.0%
ARP62700 Rat ARHGEF18 antibody; Rattus norvegicus ARHGEF18 antibody F1LT94 86.0%
ARP62699 Rhesus macaque ARHGEF18 antibody; Macaca mulatta ARHGEF18 antibody H9F3R2 100.0%
ARP62700 Rhesus macaque ARHGEF18 antibody; Macaca mulatta ARHGEF18 antibody H9F3R2 100.0%
ARP62699 Sumatran orangutan ARHGEF18 antibody; Pongo abelii ARHGEF18 antibody H2NXA1 100.0%
ARP62700 Sumatran orangutan ARHGEF18 antibody; Pongo abelii ARHGEF18 antibody H2NXA1 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas213039_at721_B_lymphoblasts442.950142.040Details
BioGPS Gene Atlas213039_atAdipocyte10.750142.040Details
BioGPS Gene Atlas213039_atAdrenalCortex10.300142.040Details
BioGPS Gene Atlas213039_atAdrenalgland57.900142.040Details
BioGPS Gene Atlas213039_atAmygdala74.800142.040Details
BioGPS Gene Atlas213039_atAppendix7.650142.040Details
BioGPS Gene Atlas213039_atAtrioventricularNode4.700142.040Details
BioGPS Gene Atlas213039_atBDCA4+_DentriticCells469.750142.040Details
BioGPS Gene Atlas213039_atBonemarrow128.300142.040Details
BioGPS Gene Atlas213039_atBronchialEpithelialCells219.450142.040Details
BioGPS Gene Atlas213039_atCD105+_Endothelial103.500142.040Details
BioGPS Gene Atlas213039_atCD14+_Monocytes319.900142.040Details
BioGPS Gene Atlas213039_atCD19+_BCells(neg._sel.)1369.250142.040Details
BioGPS Gene Atlas213039_atCD33+_Myeloid411.900142.040Details
BioGPS Gene Atlas213039_atCD34+326.100142.040Details
BioGPS Gene Atlas213039_atCD4+_Tcells1188.600142.040Details
BioGPS Gene Atlas213039_atCD56+_NKCells731.850142.040Details
BioGPS Gene Atlas213039_atCD71+_EarlyErythroid30.250142.040Details
BioGPS Gene Atlas213039_atCD8+_Tcells964.650142.040Details
BioGPS Gene Atlas213039_atCardiacMyocytes12.600142.040Details
BioGPS Gene Atlas213039_atCaudatenucleus14.850142.040Details
BioGPS Gene Atlas213039_atCerebellum48.400142.040Details
BioGPS Gene Atlas213039_atCerebellumPeduncles58.000142.040Details
BioGPS Gene Atlas213039_atCiliaryGanglion3.200142.040Details
BioGPS Gene Atlas213039_atCingulateCortex36.950142.040Details
BioGPS Gene Atlas213039_atColorectaladenocarcinoma98.050142.040Details
BioGPS Gene Atlas213039_atDorsalRootGanglion3.500142.040Details
BioGPS Gene Atlas213039_atFetalThyroid24.650142.040Details
BioGPS Gene Atlas213039_atFetalbrain47.800142.040Details
BioGPS Gene Atlas213039_atFetalliver26.800142.040Details
BioGPS Gene Atlas213039_atFetallung62.050142.040Details
BioGPS Gene Atlas213039_atGlobusPallidus19.000142.040Details
BioGPS Gene Atlas213039_atHeart66.350142.040Details
BioGPS Gene Atlas213039_atHypothalamus51.100142.040Details
BioGPS Gene Atlas213039_atKidney47.950142.040Details
BioGPS Gene Atlas213039_atLeukemia_chronicMyelogenousK-56231.950142.040Details
BioGPS Gene Atlas213039_atLeukemia_promyelocytic-HL-60203.200142.040Details
BioGPS Gene Atlas213039_atLeukemialymphoblastic(MOLT-4)100.300142.040Details
BioGPS Gene Atlas213039_atLiver97.100142.040Details
BioGPS Gene Atlas213039_atLung380.500142.040Details
BioGPS Gene Atlas213039_atLymphnode197.550142.040Details
BioGPS Gene Atlas213039_atLymphoma_burkitts(Daudi)248.100142.040Details
BioGPS Gene Atlas213039_atLymphoma_burkitts(Raji)608.100142.040Details
BioGPS Gene Atlas213039_atMedullaOblongata26.300142.040Details
BioGPS Gene Atlas213039_atOccipitalLobe41.100142.040Details
BioGPS Gene Atlas213039_atOlfactoryBulb9.550142.040Details
BioGPS Gene Atlas213039_atOvary2.550142.040Details
BioGPS Gene Atlas213039_atPancreas45.750142.040Details
BioGPS Gene Atlas213039_atPancreaticIslet33.300142.040Details
BioGPS Gene Atlas213039_atParietalLobe29.050142.040Details
BioGPS Gene Atlas213039_atPituitary41.850142.040Details
BioGPS Gene Atlas213039_atPlacenta81.200142.040Details
BioGPS Gene Atlas213039_atPons22.800142.040Details
BioGPS Gene Atlas213039_atPrefrontalCortex86.850142.040Details
BioGPS Gene Atlas213039_atProstate196.450142.040Details
BioGPS Gene Atlas213039_atSalivarygland17.550142.040Details
BioGPS Gene Atlas213039_atSkeletalMuscle6.700142.040Details
BioGPS Gene Atlas213039_atSkin3.200142.040Details
BioGPS Gene Atlas213039_atSmoothMuscle36.300142.040Details
BioGPS Gene Atlas213039_atSpinalcord32.900142.040Details
BioGPS Gene Atlas213039_atSubthalamicNucleus11.400142.040Details
BioGPS Gene Atlas213039_atSuperiorCervicalGanglion9.300142.040Details
BioGPS Gene Atlas213039_atTemporalLobe27.200142.040Details
BioGPS Gene Atlas213039_atTestis40.700142.040Details
BioGPS Gene Atlas213039_atTestisGermCell27.250142.040Details
BioGPS Gene Atlas213039_atTestisIntersitial5.800142.040Details
BioGPS Gene Atlas213039_atTestisLeydigCell5.700142.040Details
BioGPS Gene Atlas213039_atTestisSeminiferousTubule7.250142.040Details
BioGPS Gene Atlas213039_atThalamus35.450142.040Details
BioGPS Gene Atlas213039_atThymus528.800142.040Details
BioGPS Gene Atlas213039_atThyroid121.550142.040Details
BioGPS Gene Atlas213039_atTongue5.800142.040Details
BioGPS Gene Atlas213039_atTonsil92.700142.040Details
BioGPS Gene Atlas213039_atTrachea12.400142.040Details
BioGPS Gene Atlas213039_atTrigeminalGanglion5.500142.040Details
BioGPS Gene Atlas213039_atUterus75.850142.040Details
BioGPS Gene Atlas213039_atUterusCorpus8.650142.040Details
BioGPS Gene Atlas213039_atWholeBlood395.250142.040Details
BioGPS Gene Atlas213039_atWholebrain138.650142.040Details
BioGPS Gene Atlas213039_atcolon91.200142.040Details
BioGPS Gene Atlas213039_atpineal_day130.740142.040Details
BioGPS Gene Atlas213039_atpineal_night107.140142.040Details
BioGPS Gene Atlas213039_atretina57.300142.040Details
BioGPS Gene Atlas213039_atsmall_intestine69.450142.040Details
BioGPS NCI60213039_at786250.313401.440Details
BioGPS NCI60213039_atA172832.004401.440Details
BioGPS NCI60213039_atA20472.845401.440Details
BioGPS NCI60213039_atA361199.362401.440Details
BioGPS NCI60213039_atA498128.420401.440Details
BioGPS NCI60213039_atA549512.305401.440Details
BioGPS NCI60213039_atACC3473.561401.440Details
BioGPS NCI60213039_atACHN221.028401.440Details
BioGPS NCI60213039_atALVA31174.350401.440Details
BioGPS NCI60213039_atCAKI1310.904401.440Details
BioGPS NCI60213039_atCCRT CEM277.449401.440Details
BioGPS NCI60213039_atCOLO205333.040401.440Details
BioGPS NCI60213039_atDLD1312.132401.440Details
BioGPS NCI60213039_atDU145583.596401.440Details
BioGPS NCI60213039_atEKVX329.055401.440Details
BioGPS NCI60213039_atGM133281.992401.440Details
BioGPS NCI60213039_atGM1600290.095401.440Details
BioGPS NCI60213039_atGM2313169.103401.440Details
BioGPS NCI60213039_atGM2345354.580401.440Details
BioGPS NCI60213039_atGM2493170.148401.440Details
BioGPS NCI60213039_atGM97315.608401.440Details
BioGPS NCI60213039_atHCC2998315.324401.440Details
BioGPS NCI60213039_atHCT116356.248401.440Details
BioGPS NCI60213039_atHCT15940.109401.440Details
BioGPS NCI60213039_atHEK 293 T-rex169.871401.440Details
BioGPS NCI60213039_atHEK 293T180.651401.440Details
BioGPS NCI60213039_atHEK293363.204401.440Details
BioGPS NCI60213039_atHELA141.961401.440Details
BioGPS NCI60213039_atHEPG2445.320401.440Details
BioGPS NCI60213039_atHL60655.194401.440Details
BioGPS NCI60213039_atHOP62521.764401.440Details
BioGPS NCI60213039_atHOP92637.481401.440Details
BioGPS NCI60213039_atHS578T1102.093401.440Details
BioGPS NCI60213039_atHSG764.965401.440Details
BioGPS NCI60213039_atHT1080523.942401.440Details
BioGPS NCI60213039_atHT29212.287401.440Details
BioGPS NCI60213039_atIGROV1417.727401.440Details
BioGPS NCI60213039_atIOSE80661.808401.440Details
BioGPS NCI60213039_atJURKAT404.455401.440Details
BioGPS NCI60213039_atK56242.507401.440Details
BioGPS NCI60213039_atKM12278.623401.440Details
BioGPS NCI60213039_atLN18533.325401.440Details
BioGPS NCI60213039_atLNCAP120.968401.440Details
BioGPS NCI60213039_atLOX IMVI661.931401.440Details
BioGPS NCI60213039_atM14200.596401.440Details
BioGPS NCI60213039_atMALME 3M106.712401.440Details
BioGPS NCI60213039_atMCF731.064401.440Details
BioGPS NCI60213039_atMD MB231595.638401.440Details
BioGPS NCI60213039_atMDA MB435558.660401.440Details
BioGPS NCI60213039_atMOLT4502.095401.440Details
BioGPS NCI60213039_atNCI 46035.472401.440Details
BioGPS NCI60213039_atNCI H226347.223401.440Details
BioGPS NCI60213039_atNCI H23253.015401.440Details
BioGPS NCI60213039_atNCI H322M798.581401.440Details
BioGPS NCI60213039_atNCVADR RES1069.923401.440Details
BioGPS NCI60213039_atOVCAR3283.212401.440Details
BioGPS NCI60213039_atOVCAR4675.295401.440Details
BioGPS NCI60213039_atOVCAR5579.942401.440Details
BioGPS NCI60213039_atOVCAR8939.781401.440Details
BioGPS NCI60213039_atPANC1157.413401.440Details
BioGPS NCI60213039_atRL7715.479401.440Details
BioGPS NCI60213039_atRPMI 8226154.550401.440Details
BioGPS NCI60213039_atRS118461106.057401.440Details
BioGPS NCI60213039_atRXF393311.087401.440Details
BioGPS NCI60213039_atSAOS2285.637401.440Details
BioGPS NCI60213039_atSF268792.488401.440Details
BioGPS NCI60213039_atSF295515.083401.440Details
BioGPS NCI60213039_atSF539310.193401.440Details
BioGPS NCI60213039_atSHSYSY+RA238.499401.440Details
BioGPS NCI60213039_atSHSYSY-RA376.228401.440Details
BioGPS NCI60213039_atSKMEL2528.187401.440Details
BioGPS NCI60213039_atSKMEL28275.635401.440Details
BioGPS NCI60213039_atSKMEL5318.738401.440Details
BioGPS NCI60213039_atSKOV3256.073401.440Details
BioGPS NCI60213039_atSN12C354.903401.440Details
BioGPS NCI60213039_atSNB19412.878401.440Details
BioGPS NCI60213039_atSNB75460.886401.440Details
BioGPS NCI60213039_atSR134.439401.440Details
BioGPS NCI60213039_atSW620276.412401.440Details
BioGPS NCI60213039_atT24393.292401.440Details
BioGPS NCI60213039_atT3M4428.187401.440Details
BioGPS NCI60213039_atTK10113.097401.440Details
BioGPS NCI60213039_atU118583.984401.440Details
BioGPS NCI60213039_atU138245.607401.440Details
BioGPS NCI60213039_atU20S263.755401.440Details
BioGPS NCI60213039_atU251396.203401.440Details
BioGPS NCI60213039_atU87597.704401.440Details
BioGPS NCI60213039_atUACC257367.989401.440Details
BioGPS NCI60213039_atUACC62211.080401.440Details
BioGPS NCI60213039_atUO31512.036401.440Details
BioGPS NCI60213039_atZR75_1164.352401.440Details
BioGPS NCI60213039_atastrocytes232.086401.440Details
BioGPS NCI60213039_athuh-7615.188401.440Details