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Gene ID: 359 | Aqp2 Antibody Resource


Aqp2 Antibody Resource
Gene Full Name: 
aquaporin 2 (collecting duct)
Uniprot: 
P41181
Protein Name: 
aquaporin-2
Nucleotide: 
NM_000486
Alias: 
AQP-CD;WCH-CD;
Ensembl: 
ENSG00000167580
Location: 
12q12-q13
HPRD: 
00141
NCBI Gene: 
359
MIM: 
107777

Summary: 
This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. [provided by RefSeq, Oct 2008]
Function: 
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Subcellular location: 
Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus › trans-Golgi network membrane; Multi-pass membrane protein. Note: Shuttles from vesicles to the apical membrane. Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane. PLEKHA8/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated.
PTM: 
Glycoprotein;
Disease: 
Diabetes insipidus, nephrogenic, autosomal (ANDI) [MIM:125800]: A disorder caused by the inability of the renal collecting ducts to absorb water in response to arginine vasopressin. Characterized by excessive water drinking (polydipsia), excessive urine excretion (polyuria), persistent hypotonic urine, and hypokalemia. Inheritance can be autosomal dominant or recessive. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP44295_P050 Aqp2 antibody - middle region (ARP44295_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Pig, Rat, Sheep WB 50ug $289 Details
Polyclonal Antibody OASA08622 Aqp2 Antibody (OASA08622) Rat WB 0.1ml $460 Details
Polyclonal Antibody OAPC00158 Anti-Phospho-Ser261 Aquaporin 2 (OAPC00158) Rat; Mouse; Human; Bovine; Chicken; Non-human primate; Canine WB, IHC 100 ul $329 Details
Polyclonal Antibody OAPC00159 Anti-Phospho-Ser264 Aquaporin 2 (OAPC00159) Rat; Mouse; Human; Bovine; Chicken; Non-human primate; Canine WB, IHC 100 ul $329 Details
Polyclonal Antibody OAPC00160 Anti-Phospho-Ser269 Aquaporin 2 (OAPC00160) Rat; Mouse; Bovine; Canine WB, IHC 100 ul $329 Details
Polyclonal Antibody OAAF00928 AQP2 Antibody (OAAF00928) Polyclonal Human, Mouse, Rat IHC, IF, ELISA 100 ug $229 Details

Show all Aqp2 antibodies


Product Images
Aqp2 antibody - middle region (ARP44295_P050) in Mouse Heart cells using Western Blot

Sample Type: Mouse Heart

Anti-Phospho-Ser<sup>261</sup> Aquaporin 2 (OAPC00158) in Rat kidney cells using Western Blot

Sample Type: Rat kidney

Anti-Phospho-Ser<sup>264</sup> Aquaporin 2 (OAPC00159) in Rat kidney cells using Western Blot

Sample Type: Rat kidney

Anti-Phospho-Ser<sup>269</sup> Aquaporin 2 (OAPC00160) in Rat kidney cells using Western Blot

Sample Type: Rat kidney


Aqp2 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP44295 Bovine Aqp2 antibody; Bos taurus Aqp2 antibody P79099 93.0%
ARP53592 Cat Aqp2 antibody; Felis catus Aqp2 antibody M3WBH2 79.0%
ARP44295 Dog Aqp2 antibody; Canis familiaris Aqp2 antibody J9P2Y9 100.0%
ARP44295 European domestic ferret Aqp2 antibody; Mustela putorius furo Aqp2 antibody M3YSV6 100.0%
ARP44295 Giant panda Aqp2 antibody; Ailuropoda melanoleuca Aqp2 antibody G1L2L9 100.0%
ARP53592 Giant panda Aqp2 antibody; Ailuropoda melanoleuca Aqp2 antibody G1L2L9 86.0%
ARP44295 Horse Aqp2 antibody; Equus caballus Aqp2 antibody F6YNH0 93.0%
ARP44295 Human Aqp2 antibody; Homo sapiens Aqp2 antibody F8VPL3 100.0%
ARP44295 Human Aqp2 antibody; Homo sapiens Aqp2 antibody F8W0S2 100.0%
ARP44295 Human Aqp2 antibody; Homo sapiens Aqp2 antibody P41181 100.0%
ARP44295 Human Aqp2 antibody; Homo sapiens Aqp2 antibody Q6FGT3 100.0%
ARP44295 Mouse Aqp2 antibody; Mus musculus Aqp2 antibody P56402 100.0%
ARP44295 Mouse Aqp2 antibody; Mus musculus Aqp2 antibody Q3UQD4 100.0%
ARP44295 Pig Aqp2 antibody; Sus scrofa Aqp2 antibody B2MW86 93.0%
ARP44295 Rat Aqp2 antibody; Rattus norvegicus Aqp2 antibody P34080 100.0%
ARP44295 Rhesus macaque Aqp2 antibody; Macaca mulatta Aqp2 antibody F6W6H1 100.0%
ARP44295 Sheep Aqp2 antibody; Ovis aries Aqp2 antibody O62735 93.0%
ARP44295 Small-eared galago Aqp2 antibody; Otolemur garnettii Aqp2 antibody H0WQD5 93.0%
ARP44295 Sumatran orangutan Aqp2 antibody; Pongo abelii Aqp2 antibody H2NH88 100.0%
ARP44295 Thirteen-lined ground squirrel Aqp2 antibody; Spermophilus tridecemlineatus Aqp2 antibody I3MGZ1 93.0%
ARP44295 White-tufted-ear marmoset Aqp2 antibody; Callithrix jacchus Aqp2 antibody F7H018 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas206672_at721_B_lymphoblasts5.7505.200Details
BioGPS Gene Atlas206672_atAdipocyte4.4005.200Details
BioGPS Gene Atlas206672_atAdrenalCortex4.5505.200Details
BioGPS Gene Atlas206672_atAdrenalgland4.3505.200Details
BioGPS Gene Atlas206672_atAmygdala4.7005.200Details
BioGPS Gene Atlas206672_atAppendix4.8005.200Details
BioGPS Gene Atlas206672_atAtrioventricularNode4.3505.200Details
BioGPS Gene Atlas206672_atBDCA4+_DentriticCells4.6505.200Details
BioGPS Gene Atlas206672_atBonemarrow4.9005.200Details
BioGPS Gene Atlas206672_atBronchialEpithelialCells4.4505.200Details
BioGPS Gene Atlas206672_atCD105+_Endothelial4.4005.200Details
BioGPS Gene Atlas206672_atCD14+_Monocytes4.7505.200Details
BioGPS Gene Atlas206672_atCD19+_BCells(neg._sel.)4.6505.200Details
BioGPS Gene Atlas206672_atCD33+_Myeloid5.8005.200Details
BioGPS Gene Atlas206672_atCD34+5.6505.200Details
BioGPS Gene Atlas206672_atCD4+_Tcells5.6005.200Details
BioGPS Gene Atlas206672_atCD56+_NKCells5.5505.200Details
BioGPS Gene Atlas206672_atCD71+_EarlyErythroid4.1505.200Details
BioGPS Gene Atlas206672_atCD8+_Tcells4.3505.200Details
BioGPS Gene Atlas206672_atCardiacMyocytes5.5005.200Details
BioGPS Gene Atlas206672_atCaudatenucleus3.9505.200Details
BioGPS Gene Atlas206672_atCerebellum3.6005.200Details
BioGPS Gene Atlas206672_atCerebellumPeduncles5.0005.200Details
BioGPS Gene Atlas206672_atCiliaryGanglion3.7505.200Details
BioGPS Gene Atlas206672_atCingulateCortex4.6005.200Details
BioGPS Gene Atlas206672_atColorectaladenocarcinoma4.4505.200Details
BioGPS Gene Atlas206672_atDorsalRootGanglion6.7505.200Details
BioGPS Gene Atlas206672_atFetalThyroid4.3005.200Details
BioGPS Gene Atlas206672_atFetalbrain4.5505.200Details
BioGPS Gene Atlas206672_atFetalliver3.8005.200Details
BioGPS Gene Atlas206672_atFetallung3.7505.200Details
BioGPS Gene Atlas206672_atGlobusPallidus3.4005.200Details
BioGPS Gene Atlas206672_atHeart5.6005.200Details
BioGPS Gene Atlas206672_atHypothalamus4.7505.200Details
BioGPS Gene Atlas206672_atKidney54.9505.200Details
BioGPS Gene Atlas206672_atLeukemia_chronicMyelogenousK-5624.0505.200Details
BioGPS Gene Atlas206672_atLeukemia_promyelocytic-HL-603.9005.200Details
BioGPS Gene Atlas206672_atLeukemialymphoblastic(MOLT-4)3.6505.200Details
BioGPS Gene Atlas206672_atLiver5.7505.200Details
BioGPS Gene Atlas206672_atLung5.0505.200Details
BioGPS Gene Atlas206672_atLymphnode4.3005.200Details
BioGPS Gene Atlas206672_atLymphoma_burkitts(Daudi)5.6505.200Details
BioGPS Gene Atlas206672_atLymphoma_burkitts(Raji)6.1505.200Details
BioGPS Gene Atlas206672_atMedullaOblongata4.1505.200Details
BioGPS Gene Atlas206672_atOccipitalLobe4.0505.200Details
BioGPS Gene Atlas206672_atOlfactoryBulb3.5505.200Details
BioGPS Gene Atlas206672_atOvary3.1505.200Details
BioGPS Gene Atlas206672_atPancreas3.6005.200Details
BioGPS Gene Atlas206672_atPancreaticIslet4.8505.200Details
BioGPS Gene Atlas206672_atParietalLobe4.7005.200Details
BioGPS Gene Atlas206672_atPituitary5.2505.200Details
BioGPS Gene Atlas206672_atPlacenta4.6005.200Details
BioGPS Gene Atlas206672_atPons4.5505.200Details
BioGPS Gene Atlas206672_atPrefrontalCortex5.2005.200Details
BioGPS Gene Atlas206672_atProstate5.4505.200Details
BioGPS Gene Atlas206672_atSalivarygland3.6505.200Details
BioGPS Gene Atlas206672_atSkeletalMuscle5.0505.200Details
BioGPS Gene Atlas206672_atSkin3.7005.200Details
BioGPS Gene Atlas206672_atSmoothMuscle5.0005.200Details
BioGPS Gene Atlas206672_atSpinalcord4.7505.200Details
BioGPS Gene Atlas206672_atSubthalamicNucleus4.0505.200Details
BioGPS Gene Atlas206672_atSuperiorCervicalGanglion4.9505.200Details
BioGPS Gene Atlas206672_atTemporalLobe4.2005.200Details
BioGPS Gene Atlas206672_atTestis4.4005.200Details
BioGPS Gene Atlas206672_atTestisGermCell3.8005.200Details
BioGPS Gene Atlas206672_atTestisIntersitial3.7005.200Details
BioGPS Gene Atlas206672_atTestisLeydigCell5.0005.200Details
BioGPS Gene Atlas206672_atTestisSeminiferousTubule3.8505.200Details
BioGPS Gene Atlas206672_atThalamus4.5005.200Details
BioGPS Gene Atlas206672_atThymus3.6005.200Details
BioGPS Gene Atlas206672_atThyroid5.6505.200Details
BioGPS Gene Atlas206672_atTongue5.0505.200Details
BioGPS Gene Atlas206672_atTonsil4.3505.200Details
BioGPS Gene Atlas206672_atTrachea3.7005.200Details
BioGPS Gene Atlas206672_atTrigeminalGanglion4.3505.200Details
BioGPS Gene Atlas206672_atUterus3.7005.200Details
BioGPS Gene Atlas206672_atUterusCorpus4.5505.200Details
BioGPS Gene Atlas206672_atWholeBlood5.1505.200Details
BioGPS Gene Atlas206672_atWholebrain3.6005.200Details
BioGPS Gene Atlas206672_atcolon4.4005.200Details
BioGPS Gene Atlas206672_atpineal_day5.7205.200Details
BioGPS Gene Atlas206672_atpineal_night5.4605.200Details
BioGPS Gene Atlas206672_atretina5.3505.200Details
BioGPS Gene Atlas206672_atsmall_intestine4.2505.200Details
BioGPS NCI60206672_at7867.0597.230Details
BioGPS NCI60206672_atA1726.7487.230Details
BioGPS NCI60206672_atA2046.9097.230Details
BioGPS NCI60206672_atA3617.0007.230Details
BioGPS NCI60206672_atA4986.9557.230Details
BioGPS NCI60206672_atA5497.0607.230Details
BioGPS NCI60206672_atACC37.1677.230Details
BioGPS NCI60206672_atACHN6.6397.230Details
BioGPS NCI60206672_atALVA317.2347.230Details
BioGPS NCI60206672_atCAKI17.8357.230Details
BioGPS NCI60206672_atCCRT CEM7.4787.230Details
BioGPS NCI60206672_atCOLO2056.9587.230Details
BioGPS NCI60206672_atDLD16.8857.230Details
BioGPS NCI60206672_atDU1456.3877.230Details
BioGPS NCI60206672_atEKVX6.3917.230Details
BioGPS NCI60206672_atGM1337.1467.230Details
BioGPS NCI60206672_atGM16007.2217.230Details
BioGPS NCI60206672_atGM23137.0447.230Details
BioGPS NCI60206672_atGM23457.0007.230Details
BioGPS NCI60206672_atGM24937.2247.230Details
BioGPS NCI60206672_atGM977.2707.230Details
BioGPS NCI60206672_atHCC29986.4997.230Details
BioGPS NCI60206672_atHCT1166.9427.230Details
BioGPS NCI60206672_atHCT156.2137.230Details
BioGPS NCI60206672_atHEK 293 T-rex7.3337.230Details
BioGPS NCI60206672_atHEK 293T7.0787.230Details
BioGPS NCI60206672_atHEK2937.0957.230Details
BioGPS NCI60206672_atHELA4.9367.230Details
BioGPS NCI60206672_atHEPG26.9687.230Details
BioGPS NCI60206672_atHL607.0237.230Details
BioGPS NCI60206672_atHOP627.0257.230Details
BioGPS NCI60206672_atHOP926.5747.230Details
BioGPS NCI60206672_atHS578T6.8817.230Details
BioGPS NCI60206672_atHSG6.4687.230Details
BioGPS NCI60206672_atHT10806.9207.230Details
BioGPS NCI60206672_atHT297.1767.230Details
BioGPS NCI60206672_atIGROV16.9147.230Details
BioGPS NCI60206672_atIOSE806.9877.230Details
BioGPS NCI60206672_atJURKAT6.9867.230Details
BioGPS NCI60206672_atK5627.2717.230Details
BioGPS NCI60206672_atKM127.1617.230Details
BioGPS NCI60206672_atLN186.7877.230Details
BioGPS NCI60206672_atLNCAP8.5967.230Details
BioGPS NCI60206672_atLOX IMVI6.9787.230Details
BioGPS NCI60206672_atM146.8687.230Details
BioGPS NCI60206672_atMALME 3M7.1887.230Details
BioGPS NCI60206672_atMCF76.7767.230Details
BioGPS NCI60206672_atMD MB2317.1487.230Details
BioGPS NCI60206672_atMDA MB4357.2507.230Details
BioGPS NCI60206672_atMOLT47.9707.230Details
BioGPS NCI60206672_atNCI 4607.3877.230Details
BioGPS NCI60206672_atNCI H2267.0797.230Details
BioGPS NCI60206672_atNCI H237.1557.230Details
BioGPS NCI60206672_atNCI H322M7.0247.230Details
BioGPS NCI60206672_atNCVADR RES6.6817.230Details
BioGPS NCI60206672_atOVCAR37.1897.230Details
BioGPS NCI60206672_atOVCAR46.9687.230Details
BioGPS NCI60206672_atOVCAR56.9147.230Details
BioGPS NCI60206672_atOVCAR86.1707.230Details
BioGPS NCI60206672_atPANC110.9937.230Details
BioGPS NCI60206672_atRL77.0587.230Details
BioGPS NCI60206672_atRPMI 82267.0787.230Details
BioGPS NCI60206672_atRS1184611.0667.230Details
BioGPS NCI60206672_atRXF3936.9087.230Details
BioGPS NCI60206672_atSAOS27.0617.230Details
BioGPS NCI60206672_atSF2686.9957.230Details
BioGPS NCI60206672_atSF29510.7667.230Details
BioGPS NCI60206672_atSF5396.7887.230Details
BioGPS NCI60206672_atSHSYSY+RA12.1037.230Details
BioGPS NCI60206672_atSHSYSY-RA9.7697.230Details
BioGPS NCI60206672_atSKMEL26.9327.230Details
BioGPS NCI60206672_atSKMEL286.9947.230Details
BioGPS NCI60206672_atSKMEL56.8797.230Details
BioGPS NCI60206672_atSKOV37.7537.230Details
BioGPS NCI60206672_atSN12C6.9087.230Details
BioGPS NCI60206672_atSNB196.8287.230Details
BioGPS NCI60206672_atSNB756.9787.230Details
BioGPS NCI60206672_atSR8.8457.230Details
BioGPS NCI60206672_atSW6209.4527.230Details
BioGPS NCI60206672_atT247.0737.230Details
BioGPS NCI60206672_atT3M47.8407.230Details
BioGPS NCI60206672_atTK106.9457.230Details
BioGPS NCI60206672_atU1186.8937.230Details
BioGPS NCI60206672_atU1386.6897.230Details
BioGPS NCI60206672_atU20S7.0167.230Details
BioGPS NCI60206672_atU2517.5627.230Details
BioGPS NCI60206672_atU876.9367.230Details
BioGPS NCI60206672_atUACC2576.9367.230Details
BioGPS NCI60206672_atUACC627.0297.230Details
BioGPS NCI60206672_atUO316.5417.230Details
BioGPS NCI60206672_atZR75_17.0917.230Details
BioGPS NCI60206672_atastrocytes7.0087.230Details
BioGPS NCI60206672_athuh-77.3627.230Details