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Gene ID: 26060 | APPL1 Antibody Resource


APPL1 Antibody Resource
Gene Full Name: 
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Uniprot: 
Q9UKG1
Protein Name: 
DCC-interacting protein 13-alpha
Nucleotide: 
NM_012096
Alias: 
APPL;DIP13alpha;
Ensembl: 
ENSG00000157500
Location: 
3p21.1-p14.3
HPRD: 
05053
NCBI Gene: 
26060
MIM: 
604299

Summary: 
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
Function: 
Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction.
Subcellular location: 
Early endosome membrane; Peripheral membrane protein. Nucleus. Note: Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF.
PTM: 
Phosphoprotein;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP54834_P050 APPL1 antibody - middle region (ARP54834_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Pig, Rat WB 50ug $289 Details
Polyclonal Antibody OAEB02115 APPL1 Antibody (OAEB02115) Bovine, Dog, Guinea pig, Horse, Mouse, Pig, Rabbit, Rat, Zebrafish WB 0.1mg $289 Details
Polyclonal Antibody OAAB06474 APPL1 antibody - C-terminal region (OAAB06474) Human; Mouse WB, IHC 400ul $289 Details
Polyclonal Antibody ARP54833_P050 APPL1 Antibody (ARP54833_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details
Polyclonal Antibody OAAF03557 APPL1 Antibody (OAAF03557) Polyclonal Human, Mouse WB, ELISA 100 ug $229 Details

Show all APPL1 antibodies


Product Images
APPL1 antibody - middle region (ARP54834_P050) in Human THP-1 cells using Western Blot

Sample Type: Human THP-1

APPL1 Antibody (OAEB02115) in Rat Aorticmooth Muscle cells using Western Blot

Sample Type: Rat Aorticmooth Muscle


APPL1 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP54833 African clawed frog APPL1 antibody; Xenopus laevis APPL1 antibody Q6P9I3 100.0%
ARP54833 African elephant APPL1 antibody; Loxodonta africana APPL1 antibody G3TCZ2 100.0%
ARP54834 African elephant APPL1 antibody; Loxodonta africana APPL1 antibody G3TCZ2 93.0%
ARP54833 Bovine APPL1 antibody; Bos taurus APPL1 antibody A5PKI0 100.0%
ARP54834 Bovine APPL1 antibody; Bos taurus APPL1 antibody A5PKI0 86.0%
ARP54833 Cat APPL1 antibody; Felis catus APPL1 antibody M3WNU1 100.0%
ARP54834 Cat APPL1 antibody; Felis catus APPL1 antibody M3WNU1 93.0%
ARP54833 Chicken APPL1 antibody; Gallus gallus APPL1 antibody E1C411 93.0%
ARP54834 Chicken APPL1 antibody; Gallus gallus APPL1 antibody E1C411 86.0%
ARP54833 Chimpanzee APPL1 antibody; Pan troglodytes APPL1 antibody H2QMU0 100.0%
ARP54834 Chimpanzee APPL1 antibody; Pan troglodytes APPL1 antibody H2QMU0 100.0%
ARP54833 Chinese softshell turtle APPL1 antibody; Pelodiscus sinensis APPL1 antibody K7FI66 93.0%
ARP54834 Chinese softshell turtle APPL1 antibody; Pelodiscus sinensis APPL1 antibody K7FI66 86.0%
ARP54833 Collared flycatcher APPL1 antibody; Ficedula albicollis APPL1 antibody U3K1E1 100.0%
ARP54833 Common turkey APPL1 antibody; Meleagris gallopavo APPL1 antibody G1N3L6 93.0%
ARP54834 Common turkey APPL1 antibody; Meleagris gallopavo APPL1 antibody G1N3L6 86.0%
ARP54833 Dog APPL1 antibody; Canis familiaris APPL1 antibody E2R6J0 100.0%
ARP54834 Dog APPL1 antibody; Canis familiaris APPL1 antibody E2R6J0 93.0%
ARP54833 Domestic duck APPL1 antibody; Anas platyrhynchos APPL1 antibody U3I9Z3 93.0%
ARP54834 Domestic duck APPL1 antibody; Anas platyrhynchos APPL1 antibody U3I9Z3 93.0%
ARP54833 European domestic ferret APPL1 antibody; Mustela putorius furo APPL1 antibody M3YZJ1 100.0%
ARP54834 European domestic ferret APPL1 antibody; Mustela putorius furo APPL1 antibody M3YZJ1 93.0%
ARP54833 Giant panda APPL1 antibody; Ailuropoda melanoleuca APPL1 antibody D2GWZ9 100.0%
ARP54834 Giant panda APPL1 antibody; Ailuropoda melanoleuca APPL1 antibody D2GWZ9 86.0%
ARP54833 Gray short-tailed opossum APPL1 antibody; Monodelphis domestica APPL1 antibody F6YCB1 100.0%
ARP54833 Green anole APPL1 antibody; Anolis carolinensis APPL1 antibody G1KEI9 93.0%
ARP54834 Green anole APPL1 antibody; Anolis carolinensis APPL1 antibody G1KEI9 93.0%
ARP54833 Horse APPL1 antibody; Equus caballus APPL1 antibody F6PPE5 100.0%
ARP54834 Horse APPL1 antibody; Equus caballus APPL1 antibody F6PPE5 93.0%
ARP54833 Human APPL1 antibody; Homo sapiens APPL1 antibody C9JAB0 100.0%
ARP54833 Human APPL1 antibody; Homo sapiens APPL1 antibody Q9UKG1 100.0%
ARP54834 Human APPL1 antibody; Homo sapiens APPL1 antibody Q9UKG1 100.0%
ARP54833 Mouse APPL1 antibody; Mus musculus APPL1 antibody Q8K3H0 100.0%
ARP54834 Mouse APPL1 antibody; Mus musculus APPL1 antibody Q8K3H0 100.0%
ARP54833 Nile tilapia APPL1 antibody; Oreochromis niloticus APPL1 antibody I3J9B8 93.0%
ARP54833 Pig APPL1 antibody; Sus scrofa APPL1 antibody B5LX40 100.0%
ARP54834 Pig APPL1 antibody; Sus scrofa APPL1 antibody B5LX40 86.0%
ARP54833 Rabbit APPL1 antibody; Oryctolagus cuniculus APPL1 antibody G1SRT1 100.0%
ARP54833 Rat APPL1 antibody; Rattus norvegicus APPL1 antibody D3ZWA8 100.0%
ARP54834 Rat APPL1 antibody; Rattus norvegicus APPL1 antibody D3ZWA8 100.0%
ARP54833 Rhesus macaque APPL1 antibody; Macaca mulatta APPL1 antibody H9EQ29 100.0%
ARP54834 Rhesus macaque APPL1 antibody; Macaca mulatta APPL1 antibody H9EQ29 86.0%
ARP54833 Small-eared galago APPL1 antibody; Otolemur garnettii APPL1 antibody H0X3Q8 100.0%
ARP54834 Small-eared galago APPL1 antibody; Otolemur garnettii APPL1 antibody H0X3Q8 100.0%
ARP54833 Sumatran orangutan APPL1 antibody; Pongo abelii APPL1 antibody H2PAF7 100.0%
ARP54834 Sumatran orangutan APPL1 antibody; Pongo abelii APPL1 antibody H2PAF7 100.0%
ARP54833 Tasmanian devil APPL1 antibody; Sarcophilus harrisii APPL1 antibody G3WXK9 100.0%
ARP54834 Tasmanian devil APPL1 antibody; Sarcophilus harrisii APPL1 antibody G3WXK9 79.0%
ARP54834 Thirteen-lined ground squirrel APPL1 antibody; Spermophilus tridecemlineatus APPL1 antibody I3MPC9 100.0%
ARP54833 Western clawed frog APPL1 antibody; Xenopus tropicalis APPL1 antibody F6X527 100.0%
ARP54833 White-tufted-ear marmoset APPL1 antibody; Callithrix jacchus APPL1 antibody F7F5E4 100.0%
ARP54834 White-tufted-ear marmoset APPL1 antibody; Callithrix jacchus APPL1 antibody F7F5E4 100.0%
ARP54833 White-tufted-ear marmoset APPL1 antibody; Callithrix jacchus APPL1 antibody F7FXM1 100.0%
ARP54834 White-tufted-ear marmoset APPL1 antibody; Callithrix jacchus APPL1 antibody F7FXM1 100.0%
ARP54833 Zebra finch APPL1 antibody; Taeniopygia guttata APPL1 antibody H0ZA25 100.0%
ARP54833 Zebrafish APPL1 antibody; Danio rerio APPL1 antibody B2XCL9 93.0%
ARP54833 Zebrafish APPL1 antibody; Danio rerio APPL1 antibody F1QA18 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas218158_s_at721_B_lymphoblasts15.70010.600Details
BioGPS Gene Atlas218158_s_atAdipocyte7.30010.600Details
BioGPS Gene Atlas218158_s_atAdrenalCortex8.30010.600Details
BioGPS Gene Atlas218158_s_atAdrenalgland6.25010.600Details
BioGPS Gene Atlas218158_s_atAmygdala36.30010.600Details
BioGPS Gene Atlas218158_s_atAppendix8.40010.600Details
BioGPS Gene Atlas218158_s_atAtrioventricularNode8.65010.600Details
BioGPS Gene Atlas218158_s_atBDCA4+_DentriticCells28.95010.600Details
BioGPS Gene Atlas218158_s_atBonemarrow7.50010.600Details
BioGPS Gene Atlas218158_s_atBronchialEpithelialCells7.05010.600Details
BioGPS Gene Atlas218158_s_atCD105+_Endothelial6.95010.600Details
BioGPS Gene Atlas218158_s_atCD14+_Monocytes8.80010.600Details
BioGPS Gene Atlas218158_s_atCD19+_BCells(neg._sel.)17.90010.600Details
BioGPS Gene Atlas218158_s_atCD33+_Myeloid16.60010.600Details
BioGPS Gene Atlas218158_s_atCD34+19.55010.600Details
BioGPS Gene Atlas218158_s_atCD4+_Tcells7.80010.600Details
BioGPS Gene Atlas218158_s_atCD56+_NKCells13.30010.600Details
BioGPS Gene Atlas218158_s_atCD71+_EarlyErythroid6.50010.600Details
BioGPS Gene Atlas218158_s_atCD8+_Tcells11.20010.600Details
BioGPS Gene Atlas218158_s_atCardiacMyocytes9.85010.600Details
BioGPS Gene Atlas218158_s_atCaudatenucleus6.40010.600Details
BioGPS Gene Atlas218158_s_atCerebellum6.35010.600Details
BioGPS Gene Atlas218158_s_atCerebellumPeduncles8.70010.600Details
BioGPS Gene Atlas218158_s_atCiliaryGanglion5.85010.600Details
BioGPS Gene Atlas218158_s_atCingulateCortex7.90010.600Details
BioGPS Gene Atlas218158_s_atColorectaladenocarcinoma15.40010.600Details
BioGPS Gene Atlas218158_s_atDorsalRootGanglion6.75010.600Details
BioGPS Gene Atlas218158_s_atFetalThyroid7.25010.600Details
BioGPS Gene Atlas218158_s_atFetalbrain14.40010.600Details
BioGPS Gene Atlas218158_s_atFetalliver6.45010.600Details
BioGPS Gene Atlas218158_s_atFetallung6.80010.600Details
BioGPS Gene Atlas218158_s_atGlobusPallidus5.80010.600Details
BioGPS Gene Atlas218158_s_atHeart9.80010.600Details
BioGPS Gene Atlas218158_s_atHypothalamus9.80010.600Details
BioGPS Gene Atlas218158_s_atKidney6.35010.600Details
BioGPS Gene Atlas218158_s_atLeukemia_chronicMyelogenousK-5626.30010.600Details
BioGPS Gene Atlas218158_s_atLeukemia_promyelocytic-HL-6011.65010.600Details
BioGPS Gene Atlas218158_s_atLeukemialymphoblastic(MOLT-4)6.50010.600Details
BioGPS Gene Atlas218158_s_atLiver10.30010.600Details
BioGPS Gene Atlas218158_s_atLung7.75010.600Details
BioGPS Gene Atlas218158_s_atLymphnode11.00010.600Details
BioGPS Gene Atlas218158_s_atLymphoma_burkitts(Daudi)21.65010.600Details
BioGPS Gene Atlas218158_s_atLymphoma_burkitts(Raji)24.60010.600Details
BioGPS Gene Atlas218158_s_atMedullaOblongata6.45010.600Details
BioGPS Gene Atlas218158_s_atOccipitalLobe8.95010.600Details
BioGPS Gene Atlas218158_s_atOlfactoryBulb5.40010.600Details
BioGPS Gene Atlas218158_s_atOvary6.70010.600Details
BioGPS Gene Atlas218158_s_atPancreas6.25010.600Details
BioGPS Gene Atlas218158_s_atPancreaticIslet13.05010.600Details
BioGPS Gene Atlas218158_s_atParietalLobe8.10010.600Details
BioGPS Gene Atlas218158_s_atPituitary9.00010.600Details
BioGPS Gene Atlas218158_s_atPlacenta6.85010.600Details
BioGPS Gene Atlas218158_s_atPons6.95010.600Details
BioGPS Gene Atlas218158_s_atPrefrontalCortex15.20010.600Details
BioGPS Gene Atlas218158_s_atProstate12.65010.600Details
BioGPS Gene Atlas218158_s_atSalivarygland6.20010.600Details
BioGPS Gene Atlas218158_s_atSkeletalMuscle9.00010.600Details
BioGPS Gene Atlas218158_s_atSkin7.75010.600Details
BioGPS Gene Atlas218158_s_atSmoothMuscle8.30010.600Details
BioGPS Gene Atlas218158_s_atSpinalcord8.65010.600Details
BioGPS Gene Atlas218158_s_atSubthalamicNucleus7.20010.600Details
BioGPS Gene Atlas218158_s_atSuperiorCervicalGanglion8.75010.600Details
BioGPS Gene Atlas218158_s_atTemporalLobe6.85010.600Details
BioGPS Gene Atlas218158_s_atTestis5.95010.600Details
BioGPS Gene Atlas218158_s_atTestisGermCell7.55010.600Details
BioGPS Gene Atlas218158_s_atTestisIntersitial6.10010.600Details
BioGPS Gene Atlas218158_s_atTestisLeydigCell7.30010.600Details
BioGPS Gene Atlas218158_s_atTestisSeminiferousTubule5.95010.600Details
BioGPS Gene Atlas218158_s_atThalamus7.95010.600Details
BioGPS Gene Atlas218158_s_atThymus5.70010.600Details
BioGPS Gene Atlas218158_s_atThyroid48.00010.600Details
BioGPS Gene Atlas218158_s_atTongue8.10010.600Details
BioGPS Gene Atlas218158_s_atTonsil10.45010.600Details
BioGPS Gene Atlas218158_s_atTrachea6.50010.600Details
BioGPS Gene Atlas218158_s_atTrigeminalGanglion15.05010.600Details
BioGPS Gene Atlas218158_s_atUterus26.35010.600Details
BioGPS Gene Atlas218158_s_atUterusCorpus6.75010.600Details
BioGPS Gene Atlas218158_s_atWholeBlood8.40010.600Details
BioGPS Gene Atlas218158_s_atWholebrain16.20010.600Details
BioGPS Gene Atlas218158_s_atcolon21.35010.600Details
BioGPS Gene Atlas218158_s_atpineal_day8.62010.600Details
BioGPS Gene Atlas218158_s_atpineal_night8.20010.600Details
BioGPS Gene Atlas218158_s_atretina11.20010.600Details
BioGPS Gene Atlas218158_s_atsmall_intestine9.75010.600Details
BioGPS NCI60218158_s_at786161.50458.470Details
BioGPS NCI60218158_s_atA17239.79758.470Details
BioGPS NCI60218158_s_atA20473.93358.470Details
BioGPS NCI60218158_s_atA36132.41158.470Details
BioGPS NCI60218158_s_atA49820.77858.470Details
BioGPS NCI60218158_s_atA54990.94758.470Details
BioGPS NCI60218158_s_atACC343.08158.470Details
BioGPS NCI60218158_s_atACHN14.98958.470Details
BioGPS NCI60218158_s_atALVA3117.90158.470Details
BioGPS NCI60218158_s_atCAKI135.44558.470Details
BioGPS NCI60218158_s_atCCRT CEM44.41258.470Details
BioGPS NCI60218158_s_atCOLO20542.62458.470Details
BioGPS NCI60218158_s_atDLD114.44558.470Details
BioGPS NCI60218158_s_atDU14529.07058.470Details
BioGPS NCI60218158_s_atEKVX11.36758.470Details
BioGPS NCI60218158_s_atGM133180.10958.470Details
BioGPS NCI60218158_s_atGM160097.47058.470Details
BioGPS NCI60218158_s_atGM231372.57158.470Details
BioGPS NCI60218158_s_atGM2345172.07558.470Details
BioGPS NCI60218158_s_atGM2493102.64058.470Details
BioGPS NCI60218158_s_atGM97105.29958.470Details
BioGPS NCI60218158_s_atHCC299881.24958.470Details
BioGPS NCI60218158_s_atHCT11636.31858.470Details
BioGPS NCI60218158_s_atHCT15138.00758.470Details
BioGPS NCI60218158_s_atHEK 293 T-rex94.92258.470Details
BioGPS NCI60218158_s_atHEK 293T128.17758.470Details
BioGPS NCI60218158_s_atHEK293205.32758.470Details
BioGPS NCI60218158_s_atHELA18.82158.470Details
BioGPS NCI60218158_s_atHEPG226.26358.470Details
BioGPS NCI60218158_s_atHL6046.71158.470Details
BioGPS NCI60218158_s_atHOP6243.24058.470Details
BioGPS NCI60218158_s_atHOP9225.28858.470Details
BioGPS NCI60218158_s_atHS578T30.85858.470Details
BioGPS NCI60218158_s_atHSG22.26258.470Details
BioGPS NCI60218158_s_atHT108092.98058.470Details
BioGPS NCI60218158_s_atHT2954.84358.470Details
BioGPS NCI60218158_s_atIGROV112.71858.470Details
BioGPS NCI60218158_s_atIOSE8048.63758.470Details
BioGPS NCI60218158_s_atJURKAT86.47158.470Details
BioGPS NCI60218158_s_atK5629.40558.470Details
BioGPS NCI60218158_s_atKM1244.68358.470Details
BioGPS NCI60218158_s_atLN18198.20258.470Details
BioGPS NCI60218158_s_atLNCAP42.84058.470Details
BioGPS NCI60218158_s_atLOX IMVI31.23358.470Details
BioGPS NCI60218158_s_atM1480.99758.470Details
BioGPS NCI60218158_s_atMALME 3M31.35958.470Details
BioGPS NCI60218158_s_atMCF717.70758.470Details
BioGPS NCI60218158_s_atMD MB23129.65758.470Details
BioGPS NCI60218158_s_atMDA MB43513.21058.470Details
BioGPS NCI60218158_s_atMOLT430.73158.470Details
BioGPS NCI60218158_s_atNCI 46038.38058.470Details
BioGPS NCI60218158_s_atNCI H22626.79258.470Details
BioGPS NCI60218158_s_atNCI H2329.11658.470Details
BioGPS NCI60218158_s_atNCI H322M38.47958.470Details
BioGPS NCI60218158_s_atNCVADR RES27.33758.470Details
BioGPS NCI60218158_s_atOVCAR3207.62258.470Details
BioGPS NCI60218158_s_atOVCAR495.05358.470Details
BioGPS NCI60218158_s_atOVCAR545.33658.470Details
BioGPS NCI60218158_s_atOVCAR847.49358.470Details
BioGPS NCI60218158_s_atPANC19.41958.470Details
BioGPS NCI60218158_s_atRL733.60158.470Details
BioGPS NCI60218158_s_atRPMI 822657.34458.470Details
BioGPS NCI60218158_s_atRS1184670.98658.470Details
BioGPS NCI60218158_s_atRXF39326.75758.470Details
BioGPS NCI60218158_s_atSAOS210.20958.470Details
BioGPS NCI60218158_s_atSF26830.87258.470Details
BioGPS NCI60218158_s_atSF29519.42158.470Details
BioGPS NCI60218158_s_atSF53928.56458.470Details
BioGPS NCI60218158_s_atSHSYSY+RA63.64658.470Details
BioGPS NCI60218158_s_atSHSYSY-RA39.98158.470Details
BioGPS NCI60218158_s_atSKMEL250.60158.470Details
BioGPS NCI60218158_s_atSKMEL286.83958.470Details
BioGPS NCI60218158_s_atSKMEL519.39358.470Details
BioGPS NCI60218158_s_atSKOV3174.70658.470Details
BioGPS NCI60218158_s_atSN12C81.68758.470Details
BioGPS NCI60218158_s_atSNB1976.11658.470Details
BioGPS NCI60218158_s_atSNB7550.50558.470Details
BioGPS NCI60218158_s_atSR31.17258.470Details
BioGPS NCI60218158_s_atSW62033.55558.470Details
BioGPS NCI60218158_s_atT2439.40258.470Details
BioGPS NCI60218158_s_atT3M417.24658.470Details
BioGPS NCI60218158_s_atTK1037.04558.470Details
BioGPS NCI60218158_s_atU11843.96258.470Details
BioGPS NCI60218158_s_atU13870.99558.470Details
BioGPS NCI60218158_s_atU20S14.16058.470Details
BioGPS NCI60218158_s_atU25129.78858.470Details
BioGPS NCI60218158_s_atU87142.14358.470Details
BioGPS NCI60218158_s_atUACC25714.21058.470Details
BioGPS NCI60218158_s_atUACC6228.31358.470Details
BioGPS NCI60218158_s_atUO3193.60658.470Details
BioGPS NCI60218158_s_atZR75_127.23558.470Details
BioGPS NCI60218158_s_atastrocytes22.42658.470Details
BioGPS NCI60218158_s_athuh-718.93858.470Details