Search Antibody, Protein, and ELISA Kit Solutions


Gene ID: 9582 | APOBEC3B Antibody Resource


APOBEC3B Antibody Resource
Gene Full Name: 
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
Uniprot: 
Q9UH17
Protein Name: 
DNA dC->dU-editing enzyme APOBEC-3B
Nucleotide: 
XR_244398
Alias: 
A3B;ARP4;ARCD3;PHRBNL;APOBEC1L;bK150C2.2;DJ742C19.2;
Ensembl: 
ENSG00000179750
Location: 
22q13.1-q13.2
HPRD: 
06169
NCBI Gene: 
9582
MIM: 
607110

Summary: 
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
Function: 
DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons.
Subcellular location: 
Nucleus .
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP46114_P050 APOBEC3B antibody - N-terminal region (ARP46114_P050) Polyclonal Human WB 50ug $289 Details
Polyclonal Antibody OAAB09839 APOBEC3B (PHO3) antibody - C - terminal region (OAAB09839) Human; Mouse WB 400ul $289 Details

Show all APOBEC3B antibodies


Product Images
APOBEC3B antibody - N-terminal region (ARP46114_P050) in HepG2 cells using Western Blot

Sample Type: HepG2

APOBEC3B antibody - N-terminal region (ARP46114_P050) in Human HepG2 cells using Western Blot

Sample Type: Human HepG2

APOBEC3B (PHO3) antibody - C - terminal region (OAAB09839) in Mouse Testis cells using Western Blot

Sample Type: Mouse Testis


APOBEC3B Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP40254 Chimpanzee APOBEC3B antibody; Pan troglodytes APOBEC3B antibody K7BGF8 100.0%
ARP61579 Chimpanzee APOBEC3B antibody; Pan troglodytes APOBEC3B antibody H2QLP5 93.0%
ARP61579 Chimpanzee APOBEC3B antibody; Pan troglodytes APOBEC3B antibody K7AN26 93.0%
ARP61579 Chimpanzee APOBEC3B antibody; Pan troglodytes APOBEC3B antibody K7BGF8 93.0%
ARP46114 Chimpanzee APOBEC3B antibody; Pan troglodytes APOBEC3B antibody H2QLP5 86.0%
ARP61578 Chimpanzee APOBEC3B antibody; Pan troglodytes APOBEC3B antibody H2QLP5 86.0%
ARP46114 Chimpanzee APOBEC3B antibody; Pan troglodytes APOBEC3B antibody K7AN26 86.0%
ARP61578 Chimpanzee APOBEC3B antibody; Pan troglodytes APOBEC3B antibody K7AN26 86.0%
ARP46114 Chimpanzee APOBEC3B antibody; Pan troglodytes APOBEC3B antibody K7BGF8 86.0%
ARP61578 Chimpanzee APOBEC3B antibody; Pan troglodytes APOBEC3B antibody K7BGF8 86.0%
ARP46114 Chimpanzee APOBEC3B antibody; Pan troglodytes APOBEC3B antibody K7BTL7 86.0%
ARP61578 Chimpanzee APOBEC3B antibody; Pan troglodytes APOBEC3B antibody K7BTL7 86.0%
ARP61579 Chimpanzee APOBEC3B antibody; Pan troglodytes APOBEC3B antibody K7BTL7 86.0%
ARP40252 Chimpanzee APOBEC3B antibody; Pan troglodytes APOBEC3B antibody K7BGF8 79.0%
ARP46114 Human APOBEC3B antibody; Homo sapiens APOBEC3B antibody B0QYD3 100.0%
ARP46114 Human APOBEC3B antibody; Homo sapiens APOBEC3B antibody Q9UH17-2 100.0%
ARP46114 Human APOBEC3B antibody; Homo sapiens APOBEC3B antibody Q9UH17-3 100.0%
ARP46114 Human APOBEC3B antibody; Homo sapiens APOBEC3B antibody Q9UH17 100.0%
ARP61579 Human APOBEC3B antibody; Homo sapiens APOBEC3B antibody B0QYD3 93.0%
ARP61579 Human APOBEC3B antibody; Homo sapiens APOBEC3B antibody Q9UH17-3 93.0%
ARP61579 Human APOBEC3B antibody; Homo sapiens APOBEC3B antibody Q9UH17 93.0%
ARP61578 Human APOBEC3B antibody; Homo sapiens APOBEC3B antibody B0QYD3 86.0%
ARP61578 Human APOBEC3B antibody; Homo sapiens APOBEC3B antibody Q9UH17-3 86.0%
ARP61578 Human APOBEC3B antibody; Homo sapiens APOBEC3B antibody Q9UH17 86.0%
ARP61579 Rhesus macaque APOBEC3B antibody; Macaca mulatta APOBEC3B antibody F6M3K5 100.0%
ARP61579 Rhesus macaque APOBEC3B antibody; Macaca mulatta APOBEC3B antibody F6XPP0 93.0%
ARP61579 Rhesus macaque APOBEC3B antibody; Macaca mulatta APOBEC3B antibody F7FXK1 93.0%
ARP46114 Rhesus macaque APOBEC3B antibody; Macaca mulatta APOBEC3B antibody F7FXJ2 92.0%
ARP61578 Rhesus macaque APOBEC3B antibody; Macaca mulatta APOBEC3B antibody F6M3K5 86.0%
ARP61578 Rhesus macaque APOBEC3B antibody; Macaca mulatta APOBEC3B antibody F7FXJ2 86.0%
ARP61578 Rhesus macaque APOBEC3B antibody; Macaca mulatta APOBEC3B antibody F7FXK1 86.0%
ARP46114 Rhesus macaque APOBEC3B antibody; Macaca mulatta APOBEC3B antibody F6M3K5 85.0%
ARP46114 Sumatran orangutan APOBEC3B antibody; Pongo abelii APOBEC3B antibody H2P4E7 93.0%
ARP61578 Sumatran orangutan APOBEC3B antibody; Pongo abelii APOBEC3B antibody H2P4E7 86.0%
ARP61579 Sumatran orangutan APOBEC3B antibody; Pongo abelii APOBEC3B antibody H2P4E7 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas206632_s_at721_B_lymphoblasts650.00037.580Details
BioGPS Gene Atlas206632_s_atAdipocyte10.55037.580Details
BioGPS Gene Atlas206632_s_atAdrenalCortex14.70037.580Details
BioGPS Gene Atlas206632_s_atAdrenalgland9.20037.580Details
BioGPS Gene Atlas206632_s_atAmygdala9.45037.580Details
BioGPS Gene Atlas206632_s_atAppendix15.25037.580Details
BioGPS Gene Atlas206632_s_atAtrioventricularNode12.65037.580Details
BioGPS Gene Atlas206632_s_atBDCA4+_DentriticCells61.55037.580Details
BioGPS Gene Atlas206632_s_atBonemarrow53.75037.580Details
BioGPS Gene Atlas206632_s_atBronchialEpithelialCells9.65037.580Details
BioGPS Gene Atlas206632_s_atCD105+_Endothelial483.45037.580Details
BioGPS Gene Atlas206632_s_atCD14+_Monocytes10.60037.580Details
BioGPS Gene Atlas206632_s_atCD19+_BCells(neg._sel.)10.10037.580Details
BioGPS Gene Atlas206632_s_atCD33+_Myeloid12.50037.580Details
BioGPS Gene Atlas206632_s_atCD34+12.20037.580Details
BioGPS Gene Atlas206632_s_atCD4+_Tcells8.65037.580Details
BioGPS Gene Atlas206632_s_atCD56+_NKCells12.55037.580Details
BioGPS Gene Atlas206632_s_atCD71+_EarlyErythroid180.90037.580Details
BioGPS Gene Atlas206632_s_atCD8+_Tcells8.55037.580Details
BioGPS Gene Atlas206632_s_atCardiacMyocytes32.55037.580Details
BioGPS Gene Atlas206632_s_atCaudatenucleus9.00037.580Details
BioGPS Gene Atlas206632_s_atCerebellum8.20037.580Details
BioGPS Gene Atlas206632_s_atCerebellumPeduncles12.85037.580Details
BioGPS Gene Atlas206632_s_atCiliaryGanglion10.80037.580Details
BioGPS Gene Atlas206632_s_atCingulateCortex10.25037.580Details
BioGPS Gene Atlas206632_s_atColorectaladenocarcinoma816.20037.580Details
BioGPS Gene Atlas206632_s_atDorsalRootGanglion11.40037.580Details
BioGPS Gene Atlas206632_s_atFetalThyroid11.90037.580Details
BioGPS Gene Atlas206632_s_atFetalbrain9.15037.580Details
BioGPS Gene Atlas206632_s_atFetalliver21.45037.580Details
BioGPS Gene Atlas206632_s_atFetallung7.80037.580Details
BioGPS Gene Atlas206632_s_atGlobusPallidus9.00037.580Details
BioGPS Gene Atlas206632_s_atHeart18.35037.580Details
BioGPS Gene Atlas206632_s_atHypothalamus9.80037.580Details
BioGPS Gene Atlas206632_s_atKidney9.55037.580Details
BioGPS Gene Atlas206632_s_atLeukemia_chronicMyelogenousK-56228.65037.580Details
BioGPS Gene Atlas206632_s_atLeukemia_promyelocytic-HL-608.80037.580Details
BioGPS Gene Atlas206632_s_atLeukemialymphoblastic(MOLT-4)6.85037.580Details
BioGPS Gene Atlas206632_s_atLiver19.30037.580Details
BioGPS Gene Atlas206632_s_atLung10.95037.580Details
BioGPS Gene Atlas206632_s_atLymphnode7.70037.580Details
BioGPS Gene Atlas206632_s_atLymphoma_burkitts(Daudi)15.95037.580Details
BioGPS Gene Atlas206632_s_atLymphoma_burkitts(Raji)17.10037.580Details
BioGPS Gene Atlas206632_s_atMedullaOblongata8.85037.580Details
BioGPS Gene Atlas206632_s_atOccipitalLobe8.60037.580Details
BioGPS Gene Atlas206632_s_atOlfactoryBulb7.25037.580Details
BioGPS Gene Atlas206632_s_atOvary17.60037.580Details
BioGPS Gene Atlas206632_s_atPancreas10.05037.580Details
BioGPS Gene Atlas206632_s_atPancreaticIslet13.25037.580Details
BioGPS Gene Atlas206632_s_atParietalLobe12.10037.580Details
BioGPS Gene Atlas206632_s_atPituitary11.45037.580Details
BioGPS Gene Atlas206632_s_atPlacenta9.80037.580Details
BioGPS Gene Atlas206632_s_atPons10.00037.580Details
BioGPS Gene Atlas206632_s_atPrefrontalCortex10.55037.580Details
BioGPS Gene Atlas206632_s_atProstate11.15037.580Details
BioGPS Gene Atlas206632_s_atSalivarygland8.75037.580Details
BioGPS Gene Atlas206632_s_atSkeletalMuscle21.50037.580Details
BioGPS Gene Atlas206632_s_atSkin16.35037.580Details
BioGPS Gene Atlas206632_s_atSmoothMuscle12.70037.580Details
BioGPS Gene Atlas206632_s_atSpinalcord9.60037.580Details
BioGPS Gene Atlas206632_s_atSubthalamicNucleus9.40037.580Details
BioGPS Gene Atlas206632_s_atSuperiorCervicalGanglion31.25037.580Details
BioGPS Gene Atlas206632_s_atTemporalLobe14.45037.580Details
BioGPS Gene Atlas206632_s_atTestis8.25037.580Details
BioGPS Gene Atlas206632_s_atTestisGermCell7.75037.580Details
BioGPS Gene Atlas206632_s_atTestisIntersitial8.80037.580Details
BioGPS Gene Atlas206632_s_atTestisLeydigCell10.80037.580Details
BioGPS Gene Atlas206632_s_atTestisSeminiferousTubule8.50037.580Details
BioGPS Gene Atlas206632_s_atThalamus10.25037.580Details
BioGPS Gene Atlas206632_s_atThymus7.75037.580Details
BioGPS Gene Atlas206632_s_atThyroid11.70037.580Details
BioGPS Gene Atlas206632_s_atTongue13.10037.580Details
BioGPS Gene Atlas206632_s_atTonsil12.75037.580Details
BioGPS Gene Atlas206632_s_atTrachea8.15037.580Details
BioGPS Gene Atlas206632_s_atTrigeminalGanglion18.65037.580Details
BioGPS Gene Atlas206632_s_atUterus8.35037.580Details
BioGPS Gene Atlas206632_s_atUterusCorpus13.25037.580Details
BioGPS Gene Atlas206632_s_atWholeBlood10.70037.580Details
BioGPS Gene Atlas206632_s_atWholebrain7.35037.580Details
BioGPS Gene Atlas206632_s_atcolon68.95037.580Details
BioGPS Gene Atlas206632_s_atpineal_day10.92037.580Details
BioGPS Gene Atlas206632_s_atpineal_night10.80037.580Details
BioGPS Gene Atlas206632_s_atretina11.37537.580Details
BioGPS Gene Atlas206632_s_atsmall_intestine30.30037.580Details
BioGPS NCI60206632_s_at7861734.504495.000Details
BioGPS NCI60206632_s_atA17251.200495.000Details
BioGPS NCI60206632_s_atA204930.250495.000Details
BioGPS NCI60206632_s_atA361217.937495.000Details
BioGPS NCI60206632_s_atA498286.606495.000Details
BioGPS NCI60206632_s_atA549241.777495.000Details
BioGPS NCI60206632_s_atACC3242.986495.000Details
BioGPS NCI60206632_s_atACHN1077.056495.000Details
BioGPS NCI60206632_s_atALVA31105.776495.000Details
BioGPS NCI60206632_s_atCAKI1216.404495.000Details
BioGPS NCI60206632_s_atCCRT CEM54.954495.000Details
BioGPS NCI60206632_s_atCOLO205286.378495.000Details
BioGPS NCI60206632_s_atDLD13504.508495.000Details
BioGPS NCI60206632_s_atDU14573.267495.000Details
BioGPS NCI60206632_s_atEKVX1296.587495.000Details
BioGPS NCI60206632_s_atGM1331440.809495.000Details
BioGPS NCI60206632_s_atGM1600648.302495.000Details
BioGPS NCI60206632_s_atGM2313778.344495.000Details
BioGPS NCI60206632_s_atGM2345871.044495.000Details
BioGPS NCI60206632_s_atGM2493898.965495.000Details
BioGPS NCI60206632_s_atGM97740.602495.000Details
BioGPS NCI60206632_s_atHCC2998117.712495.000Details
BioGPS NCI60206632_s_atHCT116301.459495.000Details
BioGPS NCI60206632_s_atHCT151437.390495.000Details
BioGPS NCI60206632_s_atHEK 293 T-rex228.910495.000Details
BioGPS NCI60206632_s_atHEK 293T25.036495.000Details
BioGPS NCI60206632_s_atHEK293410.379495.000Details
BioGPS NCI60206632_s_atHELA687.336495.000Details
BioGPS NCI60206632_s_atHEPG2203.765495.000Details
BioGPS NCI60206632_s_atHL6034.123495.000Details
BioGPS NCI60206632_s_atHOP62598.363495.000Details
BioGPS NCI60206632_s_atHOP927.694495.000Details
BioGPS NCI60206632_s_atHS578T914.625495.000Details
BioGPS NCI60206632_s_atHSG383.286495.000Details
BioGPS NCI60206632_s_atHT108091.542495.000Details
BioGPS NCI60206632_s_atHT29113.958495.000Details
BioGPS NCI60206632_s_atIGROV1422.979495.000Details
BioGPS NCI60206632_s_atIOSE80546.899495.000Details
BioGPS NCI60206632_s_atJURKAT7.943495.000Details
BioGPS NCI60206632_s_atK562667.409495.000Details
BioGPS NCI60206632_s_atKM12383.106495.000Details
BioGPS NCI60206632_s_atLN18208.992495.000Details
BioGPS NCI60206632_s_atLNCAP8.082495.000Details
BioGPS NCI60206632_s_atLOX IMVI54.689495.000Details
BioGPS NCI60206632_s_atM14905.931495.000Details
BioGPS NCI60206632_s_atMALME 3M129.220495.000Details
BioGPS NCI60206632_s_atMCF734.350495.000Details
BioGPS NCI60206632_s_atMD MB231354.322495.000Details
BioGPS NCI60206632_s_atMDA MB4354577.026495.000Details
BioGPS NCI60206632_s_atMOLT415.865495.000Details
BioGPS NCI60206632_s_atNCI 460223.888495.000Details
BioGPS NCI60206632_s_atNCI H226610.758495.000Details
BioGPS NCI60206632_s_atNCI H23354.643495.000Details
BioGPS NCI60206632_s_atNCI H322M992.656495.000Details
BioGPS NCI60206632_s_atNCVADR RES215.102495.000Details
BioGPS NCI60206632_s_atOVCAR3138.344495.000Details
BioGPS NCI60206632_s_atOVCAR4897.807495.000Details
BioGPS NCI60206632_s_atOVCAR5966.233495.000Details
BioGPS NCI60206632_s_atOVCAR8331.455495.000Details
BioGPS NCI60206632_s_atPANC1269.829495.000Details
BioGPS NCI60206632_s_atRL718.384495.000Details
BioGPS NCI60206632_s_atRPMI 82261951.733495.000Details
BioGPS NCI60206632_s_atRS11846159.556495.000Details
BioGPS NCI60206632_s_atRXF393866.108495.000Details
BioGPS NCI60206632_s_atSAOS2537.389495.000Details
BioGPS NCI60206632_s_atSF2687.884495.000Details
BioGPS NCI60206632_s_atSF2951302.733495.000Details
BioGPS NCI60206632_s_atSF539196.759495.000Details
BioGPS NCI60206632_s_atSHSYSY+RA9.953495.000Details
BioGPS NCI60206632_s_atSHSYSY-RA7.688495.000Details
BioGPS NCI60206632_s_atSKMEL2671.999495.000Details
BioGPS NCI60206632_s_atSKMEL28139.449495.000Details
BioGPS NCI60206632_s_atSKMEL5105.823495.000Details
BioGPS NCI60206632_s_atSKOV3113.204495.000Details
BioGPS NCI60206632_s_atSN12C707.944495.000Details
BioGPS NCI60206632_s_atSNB1912.497495.000Details
BioGPS NCI60206632_s_atSNB75264.753495.000Details
BioGPS NCI60206632_s_atSR511.294495.000Details
BioGPS NCI60206632_s_atSW620652.557495.000Details
BioGPS NCI60206632_s_atT241551.654495.000Details
BioGPS NCI60206632_s_atT3M4317.615495.000Details
BioGPS NCI60206632_s_atTK10215.823495.000Details
BioGPS NCI60206632_s_atU118616.014495.000Details
BioGPS NCI60206632_s_atU138685.990495.000Details
BioGPS NCI60206632_s_atU20S514.739495.000Details
BioGPS NCI60206632_s_atU25114.527495.000Details
BioGPS NCI60206632_s_atU87511.586495.000Details
BioGPS NCI60206632_s_atUACC25741.097495.000Details
BioGPS NCI60206632_s_atUACC6229.814495.000Details
BioGPS NCI60206632_s_atUO311013.588495.000Details
BioGPS NCI60206632_s_atZR75_1495.801495.000Details
BioGPS NCI60206632_s_atastrocytes25.576495.000Details
BioGPS NCI60206632_s_athuh-719.005495.000Details