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Gene ID: 338 | APOB Antibody Resource


APOB Antibody Resource
Gene Full Name: 
apolipoprotein B
Uniprot: 
P04114
Protein Name: 
apolipoprotein B-100
Nucleotide: 
NM_000384
Alias: 
FLDB;LDLCQ4;
Ensembl: 
ENSG00000084674
Location: 
2p24-p23
HPRD: 
00133
NCBI Gene: 
338
MIM: 
107730

Summary: 
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]
Function: 
Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
Subcellular location: 
Cytoplasm. Secreted .
PTM: 
Acetylation;
Disease: 
Familial hypobetalipoproteinemia 1 (FHBL1) [MIM:107730]: A disorder of lipid metabolism characterized by less than 5th percentile age- and sex-specific levels of low density lipoproteins, and dietary fat malabsorption. Clinical presentation may vary from no symptoms to severe gastrointestinal and neurological dysfunction similar to abetalipoproteinemia. Note: The disease is caused by mutations affecting the gene represented in this entry. Familial ligand-defective apolipoprotein B-100 (FDB) [MIM:144010]: Dominantly inherited disorder of lipoprotein metabolism leading to hypercholesterolemia and increased proneness to coronary artery disease (CAD). The plasma cholesterol levels are dramatically elevated due to impaired clearance of LDL particles by defective APOB/E receptors. Note: The disease is caused by mutations affecting the gene represented in this entry. Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP41726_P050 APOB antibody - middle region (ARP41726_P050) Polyclonal Human WB, IHC 50ug $289 Details
Monoclonal Antibody OASA00956 APOB Antibody (OASA00956) Human ELISA 1mg $570 Details
Polyclonal Antibody OASA06027 APOB Antibody (OASA06027) Human TB 1ml $115 Details
Polyclonal Antibody OASA09130 APOB Antibody (OASA09130) Human ID 1ml $415 Details
Polyclonal Antibody OASA06026 APOB Antibody (OASA06026) Human ELISA, IP, WB 0.1mg $395 Details
Polyclonal Antibody OAMA03047 Rabbit anti Mouse Apo B48/100 Antibody (1ml) Mouse RID, WB 1ml $250 Details
Polyclonal Antibody OAMA03121 Goat anti Apo B-48/100 Antibody (1ml) ELISA, WB 1ml $470 Details
Polyclonal Antibody OAMA03123 Goat anti Apo B-48/100 Antibody (1ml) ELISA, WB 1ml $550 Details
Polyclonal Antibody OAMA03129 Goat anti Apo B-48/100 Antibody (1mg) ELISA, WB 1mg $310 Details
Protein OPMA04194 Human Apo B-100 Protein (1mg) 1mg $225 Details
Protein OPMA04262 Human Apolipoprotein B-100 Protein (0.5mg) 0.5mg $170 Details
Protein OPSA10464 NATIVE HUMAN APOLIPOPROTEIN B Purified Protein (0.5mg) Human 0.5mg $645 Details
Polyclonal Antibody OAEB01895 APOB Antibody (OAEB01895) Human WB 0.1mg $289 Details
Polyclonal Antibody OARA02058 APOB Antibody (OARA02058) ELISA, WB, IP, IHC 1mg $450 Details
Polyclonal Antibody ARP41725_P050 APOB Antibody (ARP41725_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details

Show all APOB antibodies


Product Images
APOB antibody - middle region (ARP41726_P050) in Human Stomach cells using Western Blot

Sample Type: Human Stomach

APOB Antibody (OAEB01895) in Humanerum cells using Western Blot

Sample Type: Humanerum


APOB Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP41726 Pan troglodytes schweinfurthii APOB antibody Q9MYL9 100.0%
ARP41726 Pan troglodytes troglodytes APOB antibody Q9MZB6 100.0%
ARP41726 Pan troglodytes verus APOB antibody Q9MZC4 100.0%
ARP41725 Cat APOB antibody; Felis catus APOB antibody M3X9R6 93.0%
ARP41726 Chimpanzee APOB antibody; Pan troglodytes APOB antibody H2R8Y5 100.0%
ARP41725 Chimpanzee APOB antibody; Pan troglodytes APOB antibody H2R8Y5 93.0%
ARP41725 Dog APOB antibody; Canis familiaris APOB antibody F1P8Z5 100.0%
ARP41725 Giant panda APOB antibody; Ailuropoda melanoleuca APOB antibody G1M3A3 86.0%
ARP41725 Horse APOB antibody; Equus caballus APOB antibody F6YCW8 100.0%
ARP41725 Horse APOB antibody; Equus caballus APOB antibody F6YE73 100.0%
ARP41725 Horse APOB antibody; Equus caballus APOB antibody F6Z5E1 100.0%
ARP41725 Human APOB antibody; Homo sapiens APOB antibody A8MUN2 100.0%
ARP41725 Human APOB antibody; Homo sapiens APOB antibody C0JYY2 100.0%
ARP41726 Human APOB antibody; Homo sapiens APOB antibody C0JYY2 100.0%
ARP41725 Human APOB antibody; Homo sapiens APOB antibody P04114 100.0%
ARP41726 Human APOB antibody; Homo sapiens APOB antibody P04114 100.0%
ARP41725 Human APOB antibody; Homo sapiens APOB antibody Q7Z7Q0 100.0%
ARP41725 Mouse APOB antibody; Mus musculus APOB antibody E9Q1Y3 86.0%
ARP41725 Mouse APOB antibody; Mus musculus APOB antibody E9Q414 86.0%
ARP41725 Mouse APOB antibody; Mus musculus APOB antibody E9Q4G4 86.0%
ARP41725 Northern white-cheeked gibbon APOB antibody; Nomascus leucogenys APOB antibody G1QIQ2 100.0%
ARP41726 Northern white-cheeked gibbon APOB antibody; Nomascus leucogenys APOB antibody G1QIQ2 100.0%
ARP41726 Pygmy chimpanzee APOB antibody; Pan paniscus APOB antibody Q9MYL8 93.0%
ARP41725 Rat APOB antibody; Rattus norvegicus APOB antibody F1M6Z1 93.0%
ARP41725 Rat APOB antibody; Rattus norvegicus APOB antibody Q7TMA5 93.0%
ARP41725 Rhesus macaque APOB antibody; Macaca mulatta APOB antibody F7CEU1 100.0%
ARP41726 Rhesus macaque APOB antibody; Macaca mulatta APOB antibody F7CEU1 86.0%
ARP41725 Small-eared galago APOB antibody; Otolemur garnettii APOB antibody H0XCJ2 93.0%
ARP41725 Sumatran orangutan APOB antibody; Pongo abelii APOB antibody H2P6V1 100.0%
ARP41726 Sumatran orangutan APOB antibody; Pongo abelii APOB antibody H2P6V1 100.0%
ARP41725 Thirteen-lined ground squirrel APOB antibody; Spermophilus tridecemlineatus APOB antibody I3N8H0 93.0%
ARP41725 White-tufted-ear marmoset APOB antibody; Callithrix jacchus APOB antibody F7HVI6 100.0%
ARP41725 White-tufted-ear marmoset APOB antibody; Callithrix jacchus APOB antibody F7HVJ1 100.0%
ARP41726 White-tufted-ear marmoset APOB antibody; Callithrix jacchus APOB antibody F7HVI6 79.0%
ARP41726 White-tufted-ear marmoset APOB antibody; Callithrix jacchus APOB antibody F7HVJ1 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas205108_s_at721_B_lymphoblasts5.50083.910Details
BioGPS Gene Atlas205108_s_atAdipocyte5.90083.910Details
BioGPS Gene Atlas205108_s_atAdrenalCortex5.25083.910Details
BioGPS Gene Atlas205108_s_atAdrenalgland4.50083.910Details
BioGPS Gene Atlas205108_s_atAmygdala4.95083.910Details
BioGPS Gene Atlas205108_s_atAppendix6.65083.910Details
BioGPS Gene Atlas205108_s_atAtrioventricularNode4.00083.910Details
BioGPS Gene Atlas205108_s_atBDCA4+_DentriticCells4.80083.910Details
BioGPS Gene Atlas205108_s_atBonemarrow5.00083.910Details
BioGPS Gene Atlas205108_s_atBronchialEpithelialCells4.70083.910Details
BioGPS Gene Atlas205108_s_atCD105+_Endothelial4.70083.910Details
BioGPS Gene Atlas205108_s_atCD14+_Monocytes5.05083.910Details
BioGPS Gene Atlas205108_s_atCD19+_BCells(neg._sel.)4.95083.910Details
BioGPS Gene Atlas205108_s_atCD33+_Myeloid5.80083.910Details
BioGPS Gene Atlas205108_s_atCD34+5.70083.910Details
BioGPS Gene Atlas205108_s_atCD4+_Tcells4.95083.910Details
BioGPS Gene Atlas205108_s_atCD56+_NKCells5.40083.910Details
BioGPS Gene Atlas205108_s_atCD71+_EarlyErythroid4.60083.910Details
BioGPS Gene Atlas205108_s_atCD8+_Tcells4.45083.910Details
BioGPS Gene Atlas205108_s_atCardiacMyocytes6.60083.910Details
BioGPS Gene Atlas205108_s_atCaudatenucleus4.35083.910Details
BioGPS Gene Atlas205108_s_atCerebellum3.95083.910Details
BioGPS Gene Atlas205108_s_atCerebellumPeduncles5.90083.910Details
BioGPS Gene Atlas205108_s_atCiliaryGanglion3.65083.910Details
BioGPS Gene Atlas205108_s_atCingulateCortex5.00083.910Details
BioGPS Gene Atlas205108_s_atColorectaladenocarcinoma4.85083.910Details
BioGPS Gene Atlas205108_s_atDorsalRootGanglion4.15083.910Details
BioGPS Gene Atlas205108_s_atFetalThyroid10.20083.910Details
BioGPS Gene Atlas205108_s_atFetalbrain4.90083.910Details
BioGPS Gene Atlas205108_s_atFetalliver4886.10083.910Details
BioGPS Gene Atlas205108_s_atFetallung1106.55083.910Details
BioGPS Gene Atlas205108_s_atGlobusPallidus3.55083.910Details
BioGPS Gene Atlas205108_s_atHeart13.35083.910Details
BioGPS Gene Atlas205108_s_atHypothalamus5.15083.910Details
BioGPS Gene Atlas205108_s_atKidney4.25083.910Details
BioGPS Gene Atlas205108_s_atLeukemia_chronicMyelogenousK-5624.30083.910Details
BioGPS Gene Atlas205108_s_atLeukemia_promyelocytic-HL-604.25083.910Details
BioGPS Gene Atlas205108_s_atLeukemialymphoblastic(MOLT-4)3.75083.910Details
BioGPS Gene Atlas205108_s_atLiver603.15083.910Details
BioGPS Gene Atlas205108_s_atLung5.95083.910Details
BioGPS Gene Atlas205108_s_atLymphnode4.00083.910Details
BioGPS Gene Atlas205108_s_atLymphoma_burkitts(Daudi)6.30083.910Details
BioGPS Gene Atlas205108_s_atLymphoma_burkitts(Raji)6.90083.910Details
BioGPS Gene Atlas205108_s_atMedullaOblongata7.05083.910Details
BioGPS Gene Atlas205108_s_atOccipitalLobe4.25083.910Details
BioGPS Gene Atlas205108_s_atOlfactoryBulb3.75083.910Details
BioGPS Gene Atlas205108_s_atOvary3.40083.910Details
BioGPS Gene Atlas205108_s_atPancreas4.05083.910Details
BioGPS Gene Atlas205108_s_atPancreaticIslet5.10083.910Details
BioGPS Gene Atlas205108_s_atParietalLobe5.95083.910Details
BioGPS Gene Atlas205108_s_atPituitary5.60083.910Details
BioGPS Gene Atlas205108_s_atPlacenta4.85083.910Details
BioGPS Gene Atlas205108_s_atPons4.75083.910Details
BioGPS Gene Atlas205108_s_atPrefrontalCortex5.75083.910Details
BioGPS Gene Atlas205108_s_atProstate5.55083.910Details
BioGPS Gene Atlas205108_s_atSalivarygland3.90083.910Details
BioGPS Gene Atlas205108_s_atSkeletalMuscle6.05083.910Details
BioGPS Gene Atlas205108_s_atSkin4.05083.910Details
BioGPS Gene Atlas205108_s_atSmoothMuscle5.30083.910Details
BioGPS Gene Atlas205108_s_atSpinalcord5.05083.910Details
BioGPS Gene Atlas205108_s_atSubthalamicNucleus4.35083.910Details
BioGPS Gene Atlas205108_s_atSuperiorCervicalGanglion8.55083.910Details
BioGPS Gene Atlas205108_s_atTemporalLobe4.50083.910Details
BioGPS Gene Atlas205108_s_atTestis4.10083.910Details
BioGPS Gene Atlas205108_s_atTestisGermCell3.90083.910Details
BioGPS Gene Atlas205108_s_atTestisIntersitial4.10083.910Details
BioGPS Gene Atlas205108_s_atTestisLeydigCell4.85083.910Details
BioGPS Gene Atlas205108_s_atTestisSeminiferousTubule4.15083.910Details
BioGPS Gene Atlas205108_s_atThalamus5.00083.910Details
BioGPS Gene Atlas205108_s_atThymus3.65083.910Details
BioGPS Gene Atlas205108_s_atThyroid5.95083.910Details
BioGPS Gene Atlas205108_s_atTongue4.95083.910Details
BioGPS Gene Atlas205108_s_atTonsil4.70083.910Details
BioGPS Gene Atlas205108_s_atTrachea4.80083.910Details
BioGPS Gene Atlas205108_s_atTrigeminalGanglion5.35083.910Details
BioGPS Gene Atlas205108_s_atUterus3.80083.910Details
BioGPS Gene Atlas205108_s_atUterusCorpus4.55083.910Details
BioGPS Gene Atlas205108_s_atWholeBlood5.40083.910Details
BioGPS Gene Atlas205108_s_atWholebrain4.05083.910Details
BioGPS Gene Atlas205108_s_atcolon7.90083.910Details
BioGPS Gene Atlas205108_s_atpineal_day5.84083.910Details
BioGPS Gene Atlas205108_s_atpineal_night5.70083.910Details
BioGPS Gene Atlas205108_s_atretina5.70083.910Details
BioGPS Gene Atlas205108_s_atsmall_intestine352.95083.910Details
BioGPS NCI60205108_s_at7864.921244.220Details
BioGPS NCI60205108_s_atA1724.494244.220Details
BioGPS NCI60205108_s_atA2044.755244.220Details
BioGPS NCI60205108_s_atA3614.818244.220Details
BioGPS NCI60205108_s_atA4984.778244.220Details
BioGPS NCI60205108_s_atA5494.930244.220Details
BioGPS NCI60205108_s_atACC35.277244.220Details
BioGPS NCI60205108_s_atACHN4.365244.220Details
BioGPS NCI60205108_s_atALVA315.241244.220Details
BioGPS NCI60205108_s_atCAKI15.057244.220Details
BioGPS NCI60205108_s_atCCRT CEM5.930244.220Details
BioGPS NCI60205108_s_atCOLO2054.855244.220Details
BioGPS NCI60205108_s_atDLD14.674244.220Details
BioGPS NCI60205108_s_atDU1454.568244.220Details
BioGPS NCI60205108_s_atEKVX4.539244.220Details
BioGPS NCI60205108_s_atGM1334.966244.220Details
BioGPS NCI60205108_s_atGM16005.276244.220Details
BioGPS NCI60205108_s_atGM23136.173244.220Details
BioGPS NCI60205108_s_atGM23454.822244.220Details
BioGPS NCI60205108_s_atGM249310.682244.220Details
BioGPS NCI60205108_s_atGM976.073244.220Details
BioGPS NCI60205108_s_atHCC29984.276244.220Details
BioGPS NCI60205108_s_atHCT1164.802244.220Details
BioGPS NCI60205108_s_atHCT154.452244.220Details
BioGPS NCI60205108_s_atHEK 293 T-rex5.144244.220Details
BioGPS NCI60205108_s_atHEK 293T4.781244.220Details
BioGPS NCI60205108_s_atHEK2934.760244.220Details
BioGPS NCI60205108_s_atHELA4.433244.220Details
BioGPS NCI60205108_s_atHEPG213729.197244.220Details
BioGPS NCI60205108_s_atHL605.263244.220Details
BioGPS NCI60205108_s_atHOP624.788244.220Details
BioGPS NCI60205108_s_atHOP924.585244.220Details
BioGPS NCI60205108_s_atHS578T4.696244.220Details
BioGPS NCI60205108_s_atHSG4.664244.220Details
BioGPS NCI60205108_s_atHT10804.697244.220Details
BioGPS NCI60205108_s_atHT295.160244.220Details
BioGPS NCI60205108_s_atIGROV14.704244.220Details
BioGPS NCI60205108_s_atIOSE804.740244.220Details
BioGPS NCI60205108_s_atJURKAT4.772244.220Details
BioGPS NCI60205108_s_atK5625.244244.220Details
BioGPS NCI60205108_s_atKM125.113244.220Details
BioGPS NCI60205108_s_atLN184.436244.220Details
BioGPS NCI60205108_s_atLNCAP4.771244.220Details
BioGPS NCI60205108_s_atLOX IMVI4.802244.220Details
BioGPS NCI60205108_s_atM144.743244.220Details
BioGPS NCI60205108_s_atMALME 3M5.206244.220Details
BioGPS NCI60205108_s_atMCF74.611244.220Details
BioGPS NCI60205108_s_atMD MB2314.882244.220Details
BioGPS NCI60205108_s_atMDA MB4355.153244.220Details
BioGPS NCI60205108_s_atMOLT44.947244.220Details
BioGPS NCI60205108_s_atNCI 4604.942244.220Details
BioGPS NCI60205108_s_atNCI H2264.976244.220Details
BioGPS NCI60205108_s_atNCI H234.787244.220Details
BioGPS NCI60205108_s_atNCI H322M4.772244.220Details
BioGPS NCI60205108_s_atNCVADR RES4.460244.220Details
BioGPS NCI60205108_s_atOVCAR35.098244.220Details
BioGPS NCI60205108_s_atOVCAR44.766244.220Details
BioGPS NCI60205108_s_atOVCAR54.680244.220Details
BioGPS NCI60205108_s_atOVCAR84.437244.220Details
BioGPS NCI60205108_s_atPANC14.835244.220Details
BioGPS NCI60205108_s_atRL74.925244.220Details
BioGPS NCI60205108_s_atRPMI 82264.866244.220Details
BioGPS NCI60205108_s_atRS118465.043244.220Details
BioGPS NCI60205108_s_atRXF3934.754244.220Details
BioGPS NCI60205108_s_atSAOS24.845244.220Details
BioGPS NCI60205108_s_atSF2684.777244.220Details
BioGPS NCI60205108_s_atSF2954.625244.220Details
BioGPS NCI60205108_s_atSF5394.451244.220Details
BioGPS NCI60205108_s_atSHSYSY+RA4.570244.220Details
BioGPS NCI60205108_s_atSHSYSY-RA4.675244.220Details
BioGPS NCI60205108_s_atSKMEL24.770244.220Details
BioGPS NCI60205108_s_atSKMEL284.803244.220Details
BioGPS NCI60205108_s_atSKMEL54.621244.220Details
BioGPS NCI60205108_s_atSKOV35.038244.220Details
BioGPS NCI60205108_s_atSN12C4.744244.220Details
BioGPS NCI60205108_s_atSNB194.469244.220Details
BioGPS NCI60205108_s_atSNB754.725244.220Details
BioGPS NCI60205108_s_atSR4.908244.220Details
BioGPS NCI60205108_s_atSW6204.841244.220Details
BioGPS NCI60205108_s_atT244.890244.220Details
BioGPS NCI60205108_s_atT3M44.983244.220Details
BioGPS NCI60205108_s_atTK104.742244.220Details
BioGPS NCI60205108_s_atU1184.654244.220Details
BioGPS NCI60205108_s_atU1384.484244.220Details
BioGPS NCI60205108_s_atU20S4.654244.220Details
BioGPS NCI60205108_s_atU2514.684244.220Details
BioGPS NCI60205108_s_atU874.609244.220Details
BioGPS NCI60205108_s_atUACC2574.671244.220Details
BioGPS NCI60205108_s_atUACC624.835244.220Details
BioGPS NCI60205108_s_atUO314.590244.220Details
BioGPS NCI60205108_s_atZR75_14.898244.220Details
BioGPS NCI60205108_s_atastrocytes4.831244.220Details
BioGPS NCI60205108_s_athuh-76066.968244.220Details