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Gene ID: 116519 | APOA5 Antibody Resource


APOA5 Antibody Resource
Gene Full Name: 
apolipoprotein A-V
Uniprot: 
Q6Q788
Protein Name: 
apolipoprotein A-V
Nucleotide: 
NM_001166598
Alias: 
RAP3;APOAV;
Ensembl: 
ENSG00000110243
Location: 
11q23
HPRD: 
06966
NCBI Gene: 
116519
MIM: 
606368

Summary: 
The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009]
Function: 
Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) . Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages.
Subcellular location: 
Secreted .
PTM: 
Phosphoprotein;
Disease: 
Hypertriglyceridemia, familial (FHTR) [MIM:145750]: A common inherited disorder in which the concentration of very low density lipoprotein (VLDL) is elevated in the plasma. This leads to increased risk of heart disease, obesity, and pancreatitis. Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.Hyperlipoproteinemia 5 (HLPP5) [MIM:144650]: Characterized by increased amounts of chylomicrons and very low density lipoprotein (VLDL) and decreased low density lipoprotein (LDL) and high density lipoprotein (HDL) in the plasma after a fast. Numerous conditions cause this phenotype, including insulin-dependent diabetes mellitus, contraceptive steroids, alcohol abuse, and glycogen storage disease type 1A (GSD1A). Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAEB02050 APOA5 Antibody (OAEB02050) Human, Mouse, Rabbit WB 0.1mg $289 Details
Polyclonal Antibody OAAB04426 APOA5 antibody - N-terminal region (OAAB04426) Human WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody OAPB01282 ApoA5 Antibody (OAPB01282) Polyclonal Human; C ELISA, WB 0.1 mg $300 Details
Others OOPA00039 APOA5 Human - Recombinant Human Apolipoprotein A-V (2ug) 2ug $100 Details
Polyclonal Antibody ARP52470_P050 APOA5 Antibody (ARP52470_P050) Polyclonal Dog, Human, Rabbit Not tested 50 ug $125 Details
Polyclonal Antibody ARP52471_P050 APOA5 Antibody (ARP52471_P050) Polyclonal Human Not tested 50 ug $125 Details
Polyclonal Antibody OAEC02487 APOA5 Antibody (OAEC02487) Human WB: 1:500~1:1000 ELISA: 1:1000 100ug $229 Details
Polyclonal Antibody OAAF03290 APOA5 Antibody (OAAF03290) Polyclonal Human WB, ELISA 100 ug $229 Details

Show all APOA5 antibodies


Product Images
APOA5 antibody - N-terminal region (OAAB04426) in HL60 cells using Western Blot

Sample Type: HL60

APOA5 antibody - N-terminal region (OAAB04426) in human hepatocarcinoma cells using Immunohistochemistry

Sample Type: human hepatocarcinoma

APOA5 Antibody (OAAF03290) in 293 cells using Western Blot

Sample Type: 293

APOA5 Antibody (OAEB02050) in Human Liver cells using Western Blot

Sample Type: Human Liver


APOA5 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP52471 Black crested mangabey APOA5 antibody; Lophocebus aterrimus APOA5 antibody H8XWI0 100.0%
ARP52471 Blue monkey APOA5 antibody; Cercopithecus mitis APOA5 antibody H8XWI1 100.0%
ARP52471 Bornean orangutan APOA5 antibody; Pongo pygmaeus APOA5 antibody H8XWH7 93.0%
ARP52470 Cat APOA5 antibody; Felis catus APOA5 antibody M3WFW9 85.0%
ARP52470 Chimpanzee APOA5 antibody; Pan troglodytes APOA5 antibody H2Q4U1 100.0%
ARP52471 Chimpanzee APOA5 antibody; Pan troglodytes APOA5 antibody H2Q4U1 100.0%
ARP52471 Common gibbon APOA5 antibody; Hylobates lar APOA5 antibody H8XWH3 100.0%
ARP52471 Common squirrel monkey APOA5 antibody; Saimiri sciureus APOA5 antibody H8XWI4 79.0%
ARP52471 Cotton-top tamarin APOA5 antibody; Saguinus oedipus APOA5 antibody H2DJB8 79.0%
ARP52471 Crab-eating macaque APOA5 antibody; Macaca fascicularis APOA5 antibody H8XWH8 100.0%
ARP52470 Dog APOA5 antibody; Canis familiaris APOA5 antibody F1PDH5 85.0%
ARP52470 Dusky titi monkey APOA5 antibody; Callicebus moloch APOA5 antibody B1MTQ7 93.0%
ARP52471 Dusky titi monkey APOA5 antibody; Callicebus moloch APOA5 antibody B1MTQ7 86.0%
ARP52470 European domestic ferret APOA5 antibody; Mustela putorius furo APOA5 antibody M3XYF9 85.0%
ARP52470 Giant panda APOA5 antibody; Ailuropoda melanoleuca APOA5 antibody G1LQ01 85.0%
ARP52471 Goeldi's marmoset APOA5 antibody; Callimico goeldii APOA5 antibody H8XWI3 79.0%
ARP52471 Green monkey APOA5 antibody; Chlorocebus aethiops APOA5 antibody H2DJB6 100.0%
ARP52470 Guinea pig APOA5 antibody; Cavia porcellus APOA5 antibody H0VR17 100.0%
ARP52471 Hanuman langur APOA5 antibody; Semnopithecus entellus APOA5 antibody H8XWH5 100.0%
ARP52470 Horse APOA5 antibody; Equus caballus APOA5 antibody F7DP84 85.0%
ARP52470 Human APOA5 antibody; Homo sapiens APOA5 antibody B0YIW1 100.0%
ARP52471 Human APOA5 antibody; Homo sapiens APOA5 antibody B0YIW1 100.0%
ARP52470 Human APOA5 antibody; Homo sapiens APOA5 antibody C9JZZ0 100.0%
ARP52470 Human APOA5 antibody; Homo sapiens APOA5 antibody Q6Q788 100.0%
ARP52471 Human APOA5 antibody; Homo sapiens APOA5 antibody Q6Q788 100.0%
ARP52471 Mantled guereza APOA5 antibody; Colobus guereza APOA5 antibody H2DJB7 100.0%
ARP52470 Nine-banded armadillo APOA5 antibody; Dasypus novemcinctus APOA5 antibody C3PSW7 83.0%
ARP52471 Olive baboon APOA5 antibody; Papio anubis APOA5 antibody A9CB28 100.0%
ARP52470 Olive baboon APOA5 antibody; Papio anubis APOA5 antibody A9CB28 93.0%
ARP52471 Proboscis monkey APOA5 antibody; Nasalis larvatus APOA5 antibody H2DJB5 100.0%
ARP52470 Rabbit APOA5 antibody; Oryctolagus cuniculus APOA5 antibody B7NZL9 86.0%
ARP52471 Red guenon APOA5 antibody; Erythrocebus patas APOA5 antibody H8XWH9 100.0%
ARP52471 Red-shanked douc langur APOA5 antibody; Pygathrix nemaeus APOA5 antibody H8XWH6 93.0%
ARP52471 Rhesus macaque APOA5 antibody; Macaca mulatta APOA5 antibody F6WX48 100.0%
ARP52470 Rhesus macaque APOA5 antibody; Macaca mulatta APOA5 antibody F6WX48 93.0%
ARP52471 Siamang APOA5 antibody; Hylobates syndactylus APOA5 antibody H8XWH4 100.0%
ARP52470 Small-eared galago APOA5 antibody; Otolemur garnettii APOA5 antibody B5SNQ1 79.0%
ARP52470 Small-eared galago APOA5 antibody; Otolemur garnettii APOA5 antibody H0XPQ1 79.0%
ARP52470 Thirteen-lined ground squirrel APOA5 antibody; Spermophilus tridecemlineatus APOA5 antibody I3MZ02 85.0%
ARP52471 western gorilla APOA5 antibody; Gorilla gorilla APOA5 antibody H2DJB9 93.0%
ARP52470 White-tufted-ear marmoset APOA5 antibody; Callithrix jacchus APOA5 antibody B0KWQ9 93.0%
ARP52471 White-tufted-ear marmoset APOA5 antibody; Callithrix jacchus APOA5 antibody B0KWQ9 86.0%

Tissue & Cell Line Gene Expression Data