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Gene ID: 147495 | APCDD1 Antibody Resource


APCDD1 Antibody Resource
Gene Full Name: 
adenomatosis polyposis coli down-regulated 1
Uniprot: 
Q8J025
Protein Name: 
protein APCDD1
Nucleotide: 
NM_153000
Alias: 
HHS;HTS;B7323;DRAPC1;FP7019;
Ensembl: 
Location: 
18p11.22
HPRD: 
09595
NCBI Gene: 
147495
MIM: 
607479

Summary: 
This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.[provided by RefSeq, Sep 2010]
Function: 
Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis.
Subcellular location: 
Cell membrane; Single-pass type I membrane protein .
PTM: 
Glycoprotein;
Disease: 
Hypotrichosis 1 (HYPT1) [MIM:605389]: A rare form of non-syndromic hereditary hypotrichosis without characteristic hair shaft anomalies. Affected individuals typically show normal hair at birth, but hair loss and thinning of the hair shaft start during early childhood and progress with age. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB09671 APCDD1 antibody - N - terminal region (OAAB09671) Human WB, IHC 400ul $289 Details

Show all APCDD1 antibodies


Product Images
APCDD1 antibody - N - terminal region (OAAB09671) in Human Liver cells using Immunohistochemistry

Sample Type: Human Liver

APCDD1 antibody - N - terminal region (OAAB09671) in NCI-H292 cells using Western Blot

Sample Type: NCI-H292


APCDD1 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP69427 African clawed frog APCDD1 antibody; Xenopus laevis APCDD1 antibody Q66KI8 79.0%
ARP69427 African elephant APCDD1 antibody; Loxodonta africana APCDD1 antibody G3T6C4 79.0%
ARP69427 Bovine APCDD1 antibody; Bos taurus APCDD1 antibody F1MNJ4 86.0%
ARP69427 Cat APCDD1 antibody; Felis catus APCDD1 antibody M3WVL1 86.0%
ARP69427 Chicken APCDD1 antibody; Gallus gallus APCDD1 antibody Q5R2I8 86.0%
ARP69427 Chimpanzee APCDD1 antibody; Pan troglodytes APCDD1 antibody H2R6V3 86.0%
ARP69427 Chimpanzee APCDD1 antibody; Pan troglodytes APCDD1 antibody K7AHR8 86.0%
ARP69427 Chinese softshell turtle APCDD1 antibody; Pelodiscus sinensis APCDD1 antibody Q5R2J4 86.0%
ARP69427 Collared flycatcher APCDD1 antibody; Ficedula albicollis APCDD1 antibody U3JV80 86.0%
ARP69427 Common turkey APCDD1 antibody; Meleagris gallopavo APCDD1 antibody G1N9Y6 86.0%
ARP69427 Dog APCDD1 antibody; Canis familiaris APCDD1 antibody E2R569 86.0%
ARP69427 Domestic duck APCDD1 antibody; Anas platyrhynchos APCDD1 antibody U3IG29 86.0%
ARP69427 European domestic ferret APCDD1 antibody; Mustela putorius furo APCDD1 antibody M3XZS3 86.0%
ARP69427 Giant panda APCDD1 antibody; Ailuropoda melanoleuca APCDD1 antibody G1LM69 86.0%
ARP69427 Gray short-tailed opossum APCDD1 antibody; Monodelphis domestica APCDD1 antibody F7BT97 86.0%
ARP69427 Green anole APCDD1 antibody; Anolis carolinensis APCDD1 antibody H9G807 86.0%
ARP69427 Guinea pig APCDD1 antibody; Cavia porcellus APCDD1 antibody H0UWU3 86.0%
ARP69427 Horse APCDD1 antibody; Equus caballus APCDD1 antibody F6ZR00 86.0%
ARP69427 Human APCDD1 antibody; Homo sapiens APCDD1 antibody Q8J025 86.0%
ARP69427 Little brown bat APCDD1 antibody; Myotis lucifugus APCDD1 antibody G1NWM1 86.0%
ARP69427 Mouse APCDD1 antibody; Mus musculus APCDD1 antibody Q3U128 86.0%
ARP69427 Nile tilapia APCDD1 antibody; Oreochromis niloticus APCDD1 antibody I3KQ76 86.0%
ARP69427 Northern white-cheeked gibbon APCDD1 antibody; Nomascus leucogenys APCDD1 antibody G1R5L9 86.0%
ARP69427 Pig APCDD1 antibody; Sus scrofa APCDD1 antibody I3LGT2 86.0%
ARP69427 Pig APCDD1 antibody; Sus scrofa APCDD1 antibody I3LVQ8 86.0%
ARP69427 Rabbit APCDD1 antibody; Oryctolagus cuniculus APCDD1 antibody G1TQ27 86.0%
ARP69427 Rat APCDD1 antibody; Rattus norvegicus APCDD1 antibody F1M5Q7 86.0%
ARP69427 Rhesus macaque APCDD1 antibody; Macaca mulatta APCDD1 antibody F7HQK8 86.0%
ARP69427 Rhesus macaque APCDD1 antibody; Macaca mulatta APCDD1 antibody G7NKC3 86.0%
ARP69427 Small-eared galago APCDD1 antibody; Otolemur garnettii APCDD1 antibody H0XBU3 86.0%
ARP69427 Spotted green pufferfish APCDD1 antibody; Tetraodon nigroviridis APCDD1 antibody H3DBL7 86.0%
ARP69427 Sumatran orangutan APCDD1 antibody; Pongo abelii APCDD1 antibody H2NVU9 86.0%
ARP69427 Thirteen-lined ground squirrel APCDD1 antibody; Spermophilus tridecemlineatus APCDD1 antibody I3MYI6 86.0%
ARP69427 Three-spined stickleback APCDD1 antibody; Gasterosteus aculeatus APCDD1 antibody G3PWM2 86.0%
ARP69427 Three-spined stickleback APCDD1 antibody; Gasterosteus aculeatus APCDD1 antibody G3PWM3 86.0%
ARP69427 Western clawed frog APCDD1 antibody; Xenopus tropicalis APCDD1 antibody F7DZN8 86.0%
ARP69427 Western clawed frog APCDD1 antibody; Xenopus tropicalis APCDD1 antibody Q6DF34 86.0%
ARP69427 White-tufted-ear marmoset APCDD1 antibody; Callithrix jacchus APCDD1 antibody F7HZ27 86.0%
ARP69427 White-tufted-ear marmoset APCDD1 antibody; Callithrix jacchus APCDD1 antibody U3DM60 86.0%
ARP69427 Zebra finch APCDD1 antibody; Taeniopygia guttata APCDD1 antibody H0ZHK2 86.0%

Tissue & Cell Line Gene Expression Data